Functionalized 3-amino-imidazo[1,2-a]pyridines: A novel class of drug-like Mycobacterium tuberculosis glutamine synthetase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 16, 2009, Pages 4790-4793

  Odell, Luke R ^a   Nilsson, Mikael T ^b   Gising, Johan ^a   Lagerlund, Olof ^a   Muthas, Daniel ^a   Nordqvist, Anneli ^a   Karlén, Anders ^a   Larhed, Mats ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

3 Aminoimidazo 1,2 a pyridine; Glutamine synthetase inhibitors; Microwave; Mycobacterium tuberculosis

Indexed keywords

3 AMINOIMIDAZO[1,2 A]PYRIDINE DERIVATIVE; ENZYME INHIBITOR; GLUTAMATE AMMONIA LIGASE; IMIDAZOPYRIDINE DERIVATIVE; METHIONINE SULFOXIMINE; PHOSPHINOTHRICIN; UNCLASSIFIED DRUG;

ARTICLE; DRUG IDENTIFICATION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; STRUCTURE ANALYSIS;

ANTITUBERCULAR AGENTS; ENZYME INHIBITORS; GLUTAMATE-AMMONIA LIGASE; IMIDAZOLES; MYCOBACTERIUM TUBERCULOSIS; PYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

MYCOBACTERIUM TUBERCULOSIS;

EID: 67651089880     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.06.045     Document Type: Article

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