Fast Pd- and Pd/Cu-catalyzed direct C - H arylation of cyclic nitrones. Application to the synthesis of enantiopure quaternary α-amino esters

Journal of Organic Chemistry

Volumn 77, Issue 18, 2012, Pages 7901-7912

  Demory, Emilien ^a   Farran, Daniel ^a   Baptiste, Benoit ^b   Chavant, Pierre Y ^a   Blandin, Véronique ^a  

^a Equipe SeRCO   (France)

^b UNIVERSITÉ JOSEPH FOURIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ESTERS; ARYLATIONS; COCATALYSIS; COPPER BROMIDE; CYCLIC NITRONES; ENANTIOPURE; LARGE ARRAYS; NITRONES; PALLADIUM-CATALYZED; PIVALIC ACID; PYRIDYL; REACTION CONDITIONS; THIENYL;

BROMINE COMPOUNDS; ESTERIFICATION; ESTERS;

CATALYSIS;

5,5 DIMETHYL 1 PYRROLINE 1 OXIDE; ALPHA METHYL ALPHA ARYLGLYCINE ESTER; CARBON; COPPER; COPPER BROMIDE; COPPER DERIVATIVE; ESTER DERIVATIVE; GLYCINE DERIVATIVE; HALIDE; HYDROGEN; NITRONE DERIVATIVE; PALLADIUM; PIVALIC ACID; UNCLASSIFIED DRUG;

ARTICLE; ARYLATION; BIOTRANSFORMATION; CATALYSIS; CATALYST; CHEMICAL BOND; CHEMICAL REACTION; CHIRALITY; CONTROLLED STUDY; CROSS COUPLING REACTION; CYCLIZATION; ENANTIOMER; ENANTIOSELECTIVITY; GRIGNARD REACTION; STEREOCHEMISTRY; SYNTHESIS;

EID: 84868145121     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo301114k     Document Type: Article

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