Palladium-catalyzed direct arylation of azine and azole N-oxides: Reaction development, scope and applications in synthesis

Journal of the American Chemical Society

Volumn 131, Issue 9, 2009, Pages 3291-3306

  Campeau, Louis Charles ^a   Stuart, David R ^a   Leclerc, Jean Philippe ^a   Bertrand Laperle, Mégan ^a   Villemure, Elisia ^a   Sun, Ho Yan ^a   Lasserre, Sandrine ^a   Guimond, Nicolas ^a   Lecavallier, Melanie ^a   Fagnou, Keith ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; AROMATIC COMPOUNDS; CATALYSIS; FUNCTIONAL GROUPS; PALLADIUM; SODIUM;

ARYLATION REACTIONS; ARYLATIONS; N-OXIDES; POTENTIAL UTILITY; PREFERENTIAL REACTION; SODIUM CHANNEL; TYROSINE KINASE INHIBITOR;

SYNTHESIS (CHEMICAL);

IMIDAZOLE DERIVATIVE; ISOQUINOLINE DERIVATIVE; LIGAND; OXIDE; PALLADIUM; PROTEIN TYROSINE KINASE INHIBITOR; PYRIDINE 1 OXIDE; QUINOLINE DERIVATIVE; SODIUM CHANNEL BLOCKING AGENT; THIAZOLE DERIVATIVE; AMINE OXIDE; ORGANOMETALLIC COMPOUND; PROTEIN KINASE INHIBITOR;

ARTICLE; ARYLATION; CATALYSIS; CHIRALITY; DEOXYGENATION; DRUG POTENCY; DRUG SYNTHESIS; OXIDATION; REACTION OPTIMIZATION; CHEMICAL STRUCTURE; CHEMISTRY; STEREOISOMERISM; SYNTHESIS;

CATALYSIS; CYCLIC N-OXIDES; MOLECULAR STRUCTURE; ORGANOMETALLIC COMPOUNDS; PALLADIUM; PROTEIN KINASE INHIBITORS; SODIUM CHANNEL BLOCKERS; STEREOISOMERISM;

EID: 67749129343     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja808332k     Document Type: Article

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