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Volumn 127, Issue 51, 2005, Pages 18020-18021

A solution to the 2-pyridyl organometallic cross-coupling problem: Regioselective catalytic direct arylation of pyridine N-oxides

Author keywords

[No Author keywords available]

Indexed keywords

ORGANOMETALLIC COMPOUND; POTASSIUM CARBONATE; PYRIDINE 1 OXIDE; PYRIDINE DERIVATIVE; TOLUENE DERIVATIVE;

EID: 29844433863     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja056800x     Document Type: Article
Times cited : (495)

References (34)
  • 4
    • 0038362703 scopus 로고    scopus 로고
    • and references therein
    • For example, see: (a) Molander, G. A.; Biolatto, B. J. Org. Chem. 2003, 68, 4302 and references therein,
    • (2003) J. Org. Chem. , vol.68 , pp. 4302
    • Molander, G.A.1    Biolatto, B.2
  • 28
    • 29844447432 scopus 로고    scopus 로고
    • note
    • Other solvents, such as dioxane, mesitylene, and N,N-dimethylacetamidc, can also be employed.
  • 29
    • 29844439628 scopus 로고    scopus 로고
    • note
    • Free pyridine is unreactive under these conditions.
  • 30
    • 0026262160 scopus 로고
    • o) for pyridine N-oxide, 288 °C; 2,6-lutidine iV-oxide, 288 °C; nicotinic acid N-oxide, 302 °C; γ-picoline N-oxide, 285 °C; picolinic acid N-oxide, 307 °C, from: Ando, T.; Fujimoto, Y.; Morisaki, S. J. Haz. Mater. 1991, 28, 251.
    • (1991) J. Haz. Mater. , vol.28 , pp. 251
    • Ando, T.1    Fujimoto, Y.2    Morisaki, S.3
  • 31
    • 29844433795 scopus 로고    scopus 로고
    • note
    • Under our standard reaction conditions, heteroaryl halides do not cross-couple in acceptable yields. This is under investigation.
  • 33
    • 0030844066 scopus 로고    scopus 로고
    • Similar yields were also obtained using zinc-mediated reduction. See: (b) Aoyagi, Y.; Abe, T.; Ohta, A. Synthesis 1997, 8, 891.
    • (1997) Synthesis , vol.8 , pp. 891
    • Aoyagi, Y.1    Abe, T.2    Ohta, A.3
  • 34
    • 29844453555 scopus 로고    scopus 로고
    • For a recent review, see: Youssif, S. ARKlVOC 2001, 242.
    • (2001) ARKlVOC , vol.242
    • Youssif, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.