Use of 5-hydroxy-4H-benzo[1,4]oxazin-3-ones as β2-adrenoceptor agonists

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 23, 2009, Pages 6640-6644

  Hoenke, Christoph ^a   Bouyssou, Thierry ^a   Tautermann, Christofer S ^a   Rudolf, Klaus ^a   Schnapp, Andreas ^a   Konetzki, Ingo ^a  

^a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

2; Adrenoceptor agonist; Asthma; Benzoxazinone; COPD; LABA

Indexed keywords

5 HYDROXY 4H BENZO[1,4]OXAZIN 3 ONE DERIVATIVE; ACETYLCHOLINE; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BRONCHODILATING AGENT; CARBOXYLIC ACID; FORMOTEROL; FORMOTEROL FUMARATE; ISOPRENALINE; LYSINE; PHENETHYLAMINE; SALIGENINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRONCHODILATATION; BRONCHOSPASM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE DURATION; DOSE RESPONSE; DRUG EFFICACY; DRUG POTENCY; DRUG SELECTIVITY; EXPERIMENTAL GUINEA PIG; FEMALE; HEART RATE; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; ONE POT SYNTHESIS;

BENZOXAZINES; DRUG DESIGN; MODELS, MOLECULAR; MOLECULAR STRUCTURE; RECEPTORS, ADRENERGIC, BETA-2; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

CAVIA;

EID: 71749104946     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.10.013     Document Type: Article

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