Selective stabilization of HIF-1α in renal tubular cells by 2-oxoglutarate analogues

American Journal of Pathology

Volumn 181, Issue 5, 2012, Pages 1595-1606

  Schley, Gunnar ^a   Klanke, Bernd ^a   Schödel, Johannes ^a   Kröning, Sven ^a   Türkoglu, Gazi ^a   Beyer, Andreas ^a   Hagos, Yohannes ^b   Amann, Kerstin ^a   Burckhardt, Birgitta C ^b   Burzlaff, Nicolai ^a   Eckardt, Kai Uwe ^a   Willam, Carsten ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOGLUTARIC ACID; 2,2' BIPYRIDINE; DIMETHYLOXALYLGLYCINE; ERYTHROPOIETIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; N OXALYLGLYCINE; ORGANIC ANION TRANSPORTER; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PYRIDINE 2,4 DICARBOXYLATE; UNCLASSIFIED DRUG; URINARY TRACT AGENT;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG TARGETING; DRUG UPTAKE; GENE ACTIVATION; GENE TARGETING; HUMAN; HUMAN CELL; HYDROPHILICITY; KIDNEY FUNCTION; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE; MALE; MOUSE; NEPHRON; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RENAL PROTECTION; REPERFUSION INJURY;

ACETIC ACID; ACUTE KIDNEY INJURY; AMINO ACIDS, DICARBOXYLIC; ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; CELL SEPARATION; GENE EXPRESSION REGULATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; ISCHEMIA; ISCHEMIC PRECONDITIONING; KETOGLUTARIC ACIDS; KIDNEY FUNCTION TESTS; KIDNEY TUBULES, PROXIMAL; MICE; ORGANIC ANION TRANSPORT PROTEIN 1; PROTEIN STABILITY; PYRIDINES;

EID: 84868095968     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2012.07.010     Document Type: Article

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