메뉴 건너뛰기




Volumn 92, Issue 5, 2012, Pages 622-630

Fruit juices as perpetrators of drug interactions: The role of organic aniontransporting polypeptides

Author keywords

[No Author keywords available]

Indexed keywords

ACEBUTOLOL; ALISKIREN; ATENOLOL; AURANTIIN; CELIPROLOL; CIPROFLOXACIN; CYTOCHROME P450 3A4; EPICATECHIN; FEXOFENADINE; GLIBENCLAMIDE; HESPERETIN; HESPERIDIN; LEVOFLOXACIN; MESSENGER RNA; MONTELUKAST; MULTIDRUG RESISTANCE PROTEIN; NARIRUTIN; ORGANIC ANION TRANSPORTER; ORGANIC ANION TRANSPORTER 1; PHLORIZIN; PITAVASTATIN; PRAVASTATIN; REPAGLINIDE; SLCO2B1 PROTEIN; TALINOLOL; THYROXINE; UNCLASSIFIED DRUG;

EID: 84867886267     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2012.159     Document Type: Review
Times cited : (67)

References (75)
  • 2
    • 34548103493 scopus 로고    scopus 로고
    • Role of OATP transporters in the disposition of drugs
    • DOI 10.2217/14622416.8.7.787
    • Niemi, M. Role of OATP transporters in the disposition of drugs. Pharmacogenomics 8, 787-802 (2007). (Pubitemid 47288978)
    • (2007) Pharmacogenomics , vol.8 , Issue.7 , pp. 787-802
    • Niemi, M.1
  • 3
    • 77649216536 scopus 로고    scopus 로고
    • Membrane transporters in drug development
    • Giacomini, K.M. et al. Membrane transporters in drug development. Nat. Rev. Drug Discov. 9, 215-236 (2010).
    • (2010) Nat. Rev. Drug Discov. , vol.9 , pp. 215-236
    • Giacomini, K.M.1
  • 7
    • 33947420519 scopus 로고    scopus 로고
    • Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice
    • DOI 10.1038/sj.clpt.6100104, PII 6100104
    • Bailey, D.G., Dresser, G.K., Leake, B.F. & Kim, R.B. Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice. Clin. Pharmacol. Ther. 81, 495-502 (2007). (Pubitemid 46452308)
    • (2007) Clinical Pharmacology and Therapeutics , vol.81 , Issue.4 , pp. 495-502
    • Bailey, D.G.1    Dresser, G.K.2    Leake, B.F.3    Kim, R.B.4
  • 8
    • 0037373594 scopus 로고    scopus 로고
    • Itraconazole increases but grapefruit juice greatly decreases plasma concentrations of celiprolol
    • DOI 10.1067/mcp.2003.26
    • Lilja, J.J., Backman, J.T., Laitila, J., Luurila, H. & Neuvonen, P.J. Itraconazole increases but grapefruit juice greatly decreases plasma concentrations of celiprolol. Clin. Pharmacol. Ther. 73, 192-198 (2003). (Pubitemid 36269670)
    • (2003) Clinical Pharmacology and Therapeutics , vol.73 , Issue.3 , pp. 192-198
    • Lilja, J.J.1    Backman, J.T.2    Laitila, J.3    Luurila, H.4    Neuvonen, P.J.5
  • 9
    • 79953906201 scopus 로고    scopus 로고
    • Orange and apple juice greatly reduce the plasma concentrations of the OATP2B1 substrate aliskiren
    • Tapaninen, T., Neuvonen, P.J. & Niemi, M. Orange and apple juice greatly reduce the plasma concentrations of the OATP2B1 substrate aliskiren. Br. J. Clin. Pharmacol. 71, 718-726 (2011).
    • (2011) Br. J. Clin. Pharmacol. , vol.71 , pp. 718-726
    • Tapaninen, T.1    Neuvonen, P.J.2    Niemi, M.3
  • 10
    • 27644463532 scopus 로고    scopus 로고
    • Effects of orange juice on the pharmacokinetics of atenolol
    • DOI 10.1007/s00228-005-0930-9
    • Lilja, J.J., Raaska, K. & Neuvonen, P.J. Effects of orange juice on the pharmacokinetics of atenolol. Eur. J. Clin. Pharmacol. 61, 337-340 (2005). (Pubitemid 41569306)
    • (2005) European Journal of Clinical Pharmacology , vol.61 , Issue.5-6 , pp. 337-340
    • Lilja, J.J.1    Raaska, K.2    Neuvonen, P.J.3
  • 11
    • 33644854071 scopus 로고    scopus 로고
    • Tissue-specific mRNA expression profiles of human ATP-binding cassette and solute carrier transporter superfamilies
    • Nishimura, M. & Naito, S. Tissue-specific mRNA expression profiles of human ATP-binding cassette and solute carrier transporter superfamilies. Drug Metab. Pharmacokinet. 20, 452-477 (2005).
    • (2005) Drug Metab. Pharmacokinet. , vol.20 , pp. 452-477
    • Nishimura, M.1    Naito, S.2
  • 13
    • 33747090656 scopus 로고    scopus 로고
    • Variability in mRNA expression of ABC- and SLC-transporters in human intestinal cells: Comparison between human segments and Caco-2 cells
    • DOI 10.1016/j.ejps.2006.03.003, PII S0928098706000820
    • Seithel, A., Karlsson, J., Hilgendorf, C., Björquist, A. & Ungell, A.L. Variability in mRNA expression of ABC-and SLC-transporters in human intestinal cells: comparison between human segments and Caco-2 cells. Eur. J. Pharm. Sci. 28, 291-299 (2006). (Pubitemid 44218740)
    • (2006) European Journal of Pharmaceutical Sciences , vol.28 , Issue.4 , pp. 291-299
    • Seithel, A.1    Karlsson, J.2    Hilgendorf, C.3    Bjorquist, A.4    Ungell, A.-L.5
  • 14
    • 34547169521 scopus 로고    scopus 로고
    • Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines
    • DOI 10.1124/dmd.107.014902
    • Hilgendorf, C., Ahlin, G., Seithel, A., Artursson, P., Ungell, A.L. & Karlsson, J. Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines. Drug Metab. Dispos. 35, 1333-1340 (2007). (Pubitemid 47121774)
    • (2007) Drug Metabolism and Disposition , vol.35 , Issue.8 , pp. 1333-1340
    • Hilgendorf, C.1    Ahlin, G.2    Seithel, A.3    Artursson, P.4    Ungell, A.-L.5    Karlsson, J.6
  • 16
    • 33747178997 scopus 로고    scopus 로고
    • Expression of transporters potentially involved in the targeting of cytostatic bile acid derivatives to colon cancer and polyps
    • DOI 10.1016/j.bcp.2006.06.007, PII S0006295206003534
    • Ballestero, M.R., Monte, M.J., Briz, O., Jimenez, F., Gonzalez-San Martin, F. & Marin, J.J. Expression of transporters potentially involved in the targeting of cytostatic bile acid derivatives to colon cancer and polyps. Biochem. Pharmacol. 72, 729-738 (2006). (Pubitemid 44233549)
    • (2006) Biochemical Pharmacology , vol.72 , Issue.6 , pp. 729-738
    • Ballestero, M.R.1    Monte, M.J.2    Briz, O.3    Jimenez, F.4    Martin, F.G.-S.5    Marin, J.J.G.6
  • 17
    • 85027940112 scopus 로고    scopus 로고
    • Environmental and genetic factors affecting transport of imatinib by OATP1A2
    • Eechoute, K. et al. Environmental and genetic factors affecting transport of imatinib by OATP1A2. Clin. Pharmacol. Ther. 89, 816-820 (2011).
    • (2011) Clin. Pharmacol. Ther. , vol.89 , pp. 816-820
    • Eechoute, K.1
  • 19
    • 15744367808 scopus 로고    scopus 로고
    • Polymorphisms in human organic anion-transporting polypeptide 1A2 (OATP1A2): Implications for altered drug disposition and central nervous system drug entry
    • DOI 10.1074/jbc.M411092200
    • Lee, W. et al. Polymorphisms in human organic anion-transporting polypeptide 1A2 (OATP1A2): implications for altered drug disposition and central nervous system drug entry. J. Biol. Chem. 280, 9610-9617 (2005). (Pubitemid 40409657)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.10 , pp. 9610-9617
    • Lee, W.1    Glaeser, H.2    Smith, L.H.3    Roberts, R.L.4    Moeckel, G.W.5    Gervasini, G.6    Leake, B.F.7    Kim, R.B.8
  • 20
    • 65649132986 scopus 로고    scopus 로고
    • Pharmacogenetics of the organic anion transporting polypeptide 1A2
    • Franke, R.M., Scherkenbach, L.A. & Sparreboom, A. Pharmacogenetics of the organic anion transporting polypeptide 1A2. Pharmacogenomics 10, 339-344 (2009).
    • (2009) Pharmacogenomics , vol.10 , pp. 339-344
    • Franke, R.M.1    Scherkenbach, L.A.2    Sparreboom, A.3
  • 21
    • 0030895921 scopus 로고    scopus 로고
    • A comparison of selected mRNA and protein abundances in human liver
    • DOI 10.1002/elps.1150180333
    • Anderson, L. & Seilhamer, J. A comparison of selected mRNA and protein abundances in human liver. Electrophoresis 18, 533-537 (1997). (Pubitemid 27174443)
    • (1997) Electrophoresis , vol.18 , Issue.3-4 , pp. 533-537
    • Anderson, L.1    Seilhamer, J.2
  • 22
    • 2442638219 scopus 로고    scopus 로고
    • Human organic anion-transporting polypeptide OATP-A (SLC21A3) acts in concert with P-glycoprotein and multidrug resistance protein 2 in the vectorial transport of Saquinavir in Hep G2 cells
    • Su, Y., Zhang, X. & Sinko, P.J. Human organic anion-transporting polypeptide OATP-A (SLC21A3) acts in concert with P-glycoprotein and multidrug resistance protein 2 in the vectorial transport of Saquinavir in Hep G2 cells. Mol. Pharm. 1, 49-56 (2004).
    • (2004) Mol. Pharm. , vol.1 , pp. 49-56
    • Su, Y.1    Zhang, X.2    Sinko, P.J.3
  • 23
    • 0038637144 scopus 로고    scopus 로고
    • Involvement of human organic anion transporting polypeptide OATP-B (SLC21A9) in pH-dependent transport across intestinal apical membrane
    • DOI 10.1124/jpet.103.051300
    • Kobayashi, D., Nozawa, T., Imai, K., Nezu, J., Tsuji, A. & Tamai, I. Involvement of human organic anion transporting polypeptide OATP-B (SLC21A9) in pH-dependent transport across intestinal apical membrane. J. Pharmacol. Exp. Ther. 306, 703-708 (2003). (Pubitemid 36886171)
    • (2003) Journal of Pharmacology and Experimental Therapeutics , vol.306 , Issue.2 , pp. 703-708
    • Kobayashi, D.1    Nozawa, T.2    Imai, K.3    Nezu, J.-I.4    Tsuji, A.5    Tamai, I.6
  • 25
    • 0033736174 scopus 로고    scopus 로고
    • Duration of effect of grapefruit juice on the pharmacokinetics of the CYP3A4 substrate simvastatin
    • Lilja, J.J., Kivistö, K.T. & Neuvonen, P.J. Duration of effect of grapefruit juice on the pharmacokinetics of the CYP3A4 substrate simvastatin. Clin. Pharmacol. Ther. 68, 384-390 (2000).
    • (2000) Clin. Pharmacol. Ther. , vol.68 , pp. 384-390
    • Lilja, J.J.1    Kivistö, K.T.2    Neuvonen, P.J.3
  • 26
    • 31044455564 scopus 로고    scopus 로고
    • Variation of flavonoids and furanocoumarins in grapefruit juices: A potential source of variability in grapefruit juice-drug interaction studies
    • DOI 10.1021/jf0516944
    • De Castro, W.V., Mertens-Talcott, S., Rubner, A., Butterweck, V. & Derendorf, H. Variation of flavonoids and furanocoumarins in grapefruit juices: a potential source of variability in grapefruit juice-drug interaction studies. J. Agric. Food Chem. 54, 249-255 (2006). (Pubitemid 43119947)
    • (2006) Journal of Agricultural and Food Chemistry , vol.54 , Issue.1 , pp. 249-255
    • De Castro, W.V.1    Mertens-Talcott, S.2    Rubner, A.3    Butterweck, V.4    Derendorf, H.5
  • 28
    • 0342868292 scopus 로고    scopus 로고
    • Role of furanocoumarin derivatives on grapefruit juice-mediated inhibition of human CYP3A activity
    • Guo, L.Q., Fukuda, K., Ohta, T. & Yamazoe, Y. Role of furanocoumarin derivatives on grapefruit juice-mediated inhibition of human CYP3A activity. Drug Metab. Dispos. 28, 766-771 (2000). (Pubitemid 30470826)
    • (2000) Drug Metabolism and Disposition , vol.28 , Issue.7 , pp. 766-771
    • Lian-Qing, G.1    Fukuda, K.2    Ohta, T.3    Yamazoe, Y.4
  • 30
    • 33845282451 scopus 로고
    • Quantitative survey of narirutin, naringin, hesperidin, and neohesperidin in citrus
    • Rouseff, R.L., Martin, S.F. & Youtsey, C.O. Quantitative survey of narirutin, naringin, hesperidin, and neohesperidin in citrus. J. Agric. Food Chem. 35, 1027-1030 (1987).
    • (1987) J. Agric. Food Chem. , vol.35 , pp. 1027-1030
    • Rouseff, R.L.1    Martin, S.F.2    Youtsey, C.O.3
  • 32
    • 79957551963 scopus 로고    scopus 로고
    • Modulation of P-glycoprotein-mediated anticancer drug accumulation, cytotoxicity, and ATPase activity by flavonoid interactions
    • Tran, V.H., Marks, D., Duke, R.K., Bebawy, M., Duke, C.C. & Roufogalis, B.D. Modulation of P-glycoprotein-mediated anticancer drug accumulation, cytotoxicity, and ATPase activity by flavonoid interactions. Nutr. Cancer 63, 435-443 (2011).
    • (2011) Nutr. Cancer , vol.63 , pp. 435-443
    • Tran, V.H.1    Marks, D.2    Duke, R.K.3    Bebawy, M.4    Duke, C.C.5    Roufogalis, B.D.6
  • 34
    • 2142711101 scopus 로고    scopus 로고
    • Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport
    • DOI 10.1124/mol.65.5.1208
    • Zhang, S., Yang, X. & Morris, M.E. Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport. Mol. Pharmacol. 65, 1208-1216 (2004). (Pubitemid 38543491)
    • (2004) Molecular Pharmacology , vol.65 , Issue.5 , pp. 1208-1216
    • Zhang, S.1    Yang, X.2    Morris, M.E.3
  • 35
    • 44249121969 scopus 로고    scopus 로고
    • Hesperidin in orange juice reduces the absorption of celiprolol in rats
    • DOI 10.1002/bdd.603
    • Uesawa, Y. & Mohri, K. Hesperidin in orange juice reduces the absorption of celiprolol in rats. Biopharm. Drug Dispos. 29, 185-188 (2008). (Pubitemid 351722163)
    • (2008) Biopharmaceutics and Drug Disposition , vol.29 , Issue.3 , pp. 185-188
    • Uesawa, Y.1    Mohri, K.2
  • 36
    • 0035794047 scopus 로고    scopus 로고
    • Determination of phenolic acids and flavonoids of apple and pear by high-performance liquid chromatography
    • DOI 10.1016/S0021-9673(00)01217-6, PII S0021967300012176
    • Schieber, A., Keller, P. & Carle, R. Determination of phenolic acids and flavonoids of apple and pear by high-performance liquid chromatography. J. Chromatogr. A 910, 265-273 (2001). (Pubitemid 32126294)
    • (2001) Journal of Chromatography A , vol.910 , Issue.2 , pp. 265-273
    • Schieber, A.1    Keller, P.2    Carle, R.3
  • 37
    • 0037021601 scopus 로고    scopus 로고
    • Activity and concentration of polyphenolic antioxidants in apple juice. 1. Effect of existing production methods
    • DOI 10.1021/jf020115h
    • Van Der Sluis, A.A., Dekker, M., Skrede, G. & Jongen, W.M. Activity and concentration of polyphenolic antioxidants in apple juice. 1. Effect of existing production methods. J. Agric. Food Chem. 50, 7211-7219 (2002). (Pubitemid 35424879)
    • (2002) Journal of Agricultural and Food Chemistry , vol.50 , Issue.25 , pp. 7211-7219
    • Van Der Sluis, A.A.1    Dekker, M.2    Skrede, G.3    Jongen, W.M.F.4
  • 39
    • 27544453625 scopus 로고    scopus 로고
    • Flavonoids as a novel class of human organic anion-transporting polypeptide OATP1B1 (OATP-C) modulators
    • DOI 10.1124/dmd.105.005926
    • Wang, X., Wolkoff, A.W. & Morris, M.E. Flavonoids as a novel class of human organic anion-transporting polypeptide OATP1B1 (OATP-C) modulators. Drug Metab. Dispos. 33, 1666-1672 (2005). (Pubitemid 41539965)
    • (2005) Drug Metabolism and Disposition , vol.33 , Issue.11 , pp. 1666-1672
    • Wang, X.1    Wolkoff, A.W.2    Morris, M.E.3
  • 40
    • 33645100643 scopus 로고    scopus 로고
    • Effects of herbal extracts on the function of human organic anion-transporting polypeptide OATP-B
    • Fuchikami, H., Satoh, H., Tsujimoto, M., Ohdo, S., Ohtani, H. & Sawada, Y. Effects of herbal extracts on the function of human organic anion-transporting polypeptide OATP-B. Drug Metab. Dispos. 34, 577-582 (2006).
    • (2006) Drug Metab. Dispos. , vol.34 , pp. 577-582
    • Fuchikami, H.1    Satoh, H.2    Tsujimoto, M.3    Ohdo, S.4    Ohtani, H.5    Sawada, Y.6
  • 41
    • 77957903556 scopus 로고    scopus 로고
    • Influence of the flavonoids apigenin, kaempferol, and quercetin on the function of organic anion transporting polypeptides 1A2 and 2B1
    • Mandery, K. et al. Influence of the flavonoids apigenin, kaempferol, and quercetin on the function of organic anion transporting polypeptides 1A2 and 2B1. Biochem. Pharmacol. 80, 1746-1753 (2010).
    • (2010) Biochem. Pharmacol. , vol.80 , pp. 1746-1753
    • Mandery, K.1
  • 42
    • 68849107630 scopus 로고    scopus 로고
    • Short-term effect of quercetin on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein, in healthy volunteers
    • Kim, K.A., Park, P.W. & Park, J.Y. Short-term effect of quercetin on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein, in healthy volunteers. Eur. J. Clin. Pharmacol. 65, 609-614 (2009).
    • (2009) Eur. J. Clin. Pharmacol. , vol.65 , pp. 609-614
    • Kim, K.A.1    Park, P.W.2    Park, J.Y.3
  • 43
    • 0030764751 scopus 로고    scopus 로고
    • Characterisation of citrus by chromatographic analysis of flavonoids
    • DOI 10.1002/(SICI)1097-0010(199709)75:1<87::AID-JSFA846>3.0.CO;2-B
    • Robards, K., Li, X., Antolovich, M. & Boyd, S. Characterisation of citrus by chromatographic analysis of flavonoids. J. Sci. Food Agric. 75, 87-101 (1997). (Pubitemid 27389676)
    • (1997) Journal of the Science of Food and Agriculture , vol.75 , Issue.1 , pp. 87-101
    • Robards, K.1    Li, X.2    Antolovich, M.3    Boyd, S.4
  • 44
    • 0036091282 scopus 로고    scopus 로고
    • Grapefruit juice reduces the oral bioavailability of fexofenadine but not desloratadine
    • Banfield, C., Gupta, S., Marino, M., Lim, J. & Affrime, M. Grapefruit juice reduces the oral bioavailability of fexofenadine but not desloratadine. Clin. Pharmacokinet. 41, 311-318 (2002). (Pubitemid 34533758)
    • (2002) Clinical pharmacokinetics , vol.41 , Issue.4 , pp. 311-318
    • Banfield, C.1    Gupta, S.2    Marino, M.3    Lim, J.4    Affrime, M.5
  • 45
    • 13944275994 scopus 로고    scopus 로고
    • Effect of grapefruit juice volume on the reduction of fexofenadine bioavailability: Possible role of organic anion transporting polypeptides
    • DOI 10.1016/j.clpt.2004.10.005
    • Dresser, G.K., Kim, R.B. & Bailey, D.G. Effect of grapefruit juice volume on the reduction of fexofenadine bioavailability: possible role of organic anion transporting polypeptides. Clin. Pharmacol. Ther. 77, 170-177 (2005). (Pubitemid 40269132)
    • (2005) Clinical Pharmacology and Therapeutics , vol.77 , Issue.3 , pp. 170-177
    • Dresser, G.K.1    Kim, R.B.2    Bailey, D.G.3
  • 46
    • 78751614878 scopus 로고    scopus 로고
    • The effects of the SLCO2B1 c.1457C > T polymorphism and apple juice on the pharmacokinetics of fexofenadine and midazolam in humans
    • Imanaga, J. et al. The effects of the SLCO2B1 c.1457C > T polymorphism and apple juice on the pharmacokinetics of fexofenadine and midazolam in humans. Pharmacogenet. Genomics 21, 84-93 (2011).
    • (2011) Pharmacogenet. Genomics , vol.21 , pp. 84-93
    • Imanaga, J.1
  • 47
    • 1642457252 scopus 로고    scopus 로고
    • Functional Characterization of pH-Sensitive Organic Anion Transporting Polypeptide OATP-B in Human
    • DOI 10.1124/jpet.103.060194
    • Nozawa, T., Imai, K., Nezu, J., Tsuji, A. & Tamai, I. Functional characterization of pH-sensitive organic anion transporting polypeptide OATP-B in human. J. Pharmacol. Exp. Ther. 308, 438-445 (2004). (Pubitemid 38134202)
    • (2004) Journal of Pharmacology and Experimental Therapeutics , vol.308 , Issue.2 , pp. 438-445
    • Nozawa, T.1    Imai, K.2    Nezu, J.-I.3    Tsuji, A.4    Tamai, I.5
  • 49
    • 1542346411 scopus 로고    scopus 로고
    • Orange juice substantially reduces the bioavailability of the beta-adrenergic-blocking agent celiprolol
    • DOI 10.1016/j.clpt.2003.11.002, PII S0009923603003369
    • Lilja, J.J., Juntti-Patinen, L. & Neuvonen, P.J. Orange juice substantially reduces the bioavailability of the beta-adrenergic-blocking agent celiprolol. Clin. Pharmacol. Ther. 75, 184-190 (2004). (Pubitemid 38314867)
    • (2004) Clinical Pharmacology and Therapeutics , vol.75 , Issue.3 , pp. 184-190
    • Lilja, J.J.1    Juntti-Patinen, L.2    Neuvonen, P.J.3
  • 50
    • 84859707877 scopus 로고    scopus 로고
    • Microdosing clinical study: Pharmacokinetic, pharmacogenomic (SLCO2B1), and interaction (grapefruit juice) profiles of celiprolol following the oral microdose and therapeutic dose
    • Ieiri, I. et al. Microdosing clinical study: pharmacokinetic, pharmacogenomic (SLCO2B1), and interaction (grapefruit juice) profiles of celiprolol following the oral microdose and therapeutic dose. J. Clin. Pharmacol. 52, 1078-1089 (2012).
    • (2012) J. Clin. Pharmacol. , vol.52 , pp. 1078-1089
    • Ieiri, I.1
  • 51
    • 84867890192 scopus 로고    scopus 로고
    • Apple juice greatly reduces systemic exposure to atenolol
    • e-pub ahead of print 11 May 2012.
    • Jeon, H.et al. Apple juice greatly reduces systemic exposure to atenolol. Br. J. Clin. Pharmacol. (2012), e-pub ahead of print 11 May 2012.
    • (2012) Br. J. Clin. Pharmacol
    • Jeon, H.1
  • 52
    • 67650106075 scopus 로고    scopus 로고
    • Involvement of influx and efflux transport systems in gastrointestinal absorption of celiprolol
    • Kato, Y., Miyazaki, T., Kano, T., Sugiura, T., Kubo, Y. & Tsuji, A. Involvement of influx and efflux transport systems in gastrointestinal absorption of celiprolol. J. Pharm. Sci. 98, 2529-2539 (2009).
    • (2009) J. Pharm. Sci. , vol.98 , pp. 2529-2539
    • Kato, Y.1    Miyazaki, T.2    Kano, T.3    Sugiura, T.4    Kubo, Y.5    Tsuji, A.6
  • 53
    • 73949086125 scopus 로고    scopus 로고
    • Species difference in the effect of grapefruit juice on intestinal absorption of talinolol between human and rat
    • Shirasaka, Y., Kuraoka, E., Spahn-Langguth, H., Nakanishi, T., Langguth, P. & Tamai, I. Species difference in the effect of grapefruit juice on intestinal absorption of talinolol between human and rat. J. Pharmacol. Exp. Ther. 332, 181-189 (2010).
    • (2010) J. Pharmacol. Exp. Ther. , vol.332 , pp. 181-189
    • Shirasaka, Y.1    Kuraoka, E.2    Spahn-Langguth, H.3    Nakanishi, T.4    Langguth, P.5    Tamai, I.6
  • 55
    • 0036202184 scopus 로고    scopus 로고
    • Lack of bioequivalence of ciprofloxacin when administered with calcium-fortified orange juice: A new twist on an old interaction
    • DOI 10.1177/0091270002424013
    • Neuhofel, A.L., Wilton, J.H., Victory, J.M., Hejmanowsk, L.G. & Amsden, G.W. Lack of bioequivalence of ciprofloxacin when administered with calcium-fortified orange juice: a new twist on an old interaction. J. Clin. Pharmacol. 42, 461-466 (2002). (Pubitemid 34259781)
    • (2002) Journal of Clinical Pharmacology , vol.42 , Issue.4 , pp. 461-466
    • Neuhofel, A.L.1    Wilton, J.H.2    Victory, J.M.3    Hejmanowski, L.G.4    Amsden, G.W.5
  • 56
    • 33847235324 scopus 로고    scopus 로고
    • Identification of influx transporter for the quinolone antibacterial agent levofloxacin
    • Maeda, T. et al. Identification of influx transporter for the quinolone antibacterial agent levofloxacin. Mol. Pharm. 4, 85-94 (2007).
    • (2007) Mol. Pharm. , vol.4 , pp. 85-94
    • Maeda, T.1
  • 57
    • 84872600941 scopus 로고    scopus 로고
    • The ciprofloxacin target AUC/MIC ratio is not reached in hospitalized patients with the recommended dosing regimens
    • e-pub ahead of print 23 May 2012.
    • Haeseker, M. et al. The ciprofloxacin target AUC/MIC ratio is not reached in hospitalized patients with the recommended dosing regimens. Br. J. Clin. Pharmacol. (2012), e-pub ahead of print 23 May 2012.
    • (2012) Br. J. Clin. Pharmacol.
    • Haeseker, M.1
  • 59
    • 59549106159 scopus 로고    scopus 로고
    • Absorption of montelukast is transporter mediated: A common variant of OATP2B1 is associated with reduced plasma concentrations and poor response
    • Mougey, E.B., Feng, H., Castro, M., Irvin, C.G. & Lima, J.J. Absorption of montelukast is transporter mediated: a common variant of OATP2B1 is associated with reduced plasma concentrations and poor response. Pharmacogenet. Genomics 19, 129-138 (2009).
    • (2009) Pharmacogenet. Genomics , vol.19 , pp. 129-138
    • Mougey, E.B.1    Feng, H.2    Castro, M.3    Irvin, C.G.4    Lima, J.J.5
  • 62
    • 79955530067 scopus 로고    scopus 로고
    • Effect of citrus juice and SLCO2B1 genotype on the pharmacokinetics of montelukast
    • Mougey, E.B., Lang, J.E., Wen, X. & Lima, J.J. Effect of citrus juice and SLCO2B1 genotype on the pharmacokinetics of montelukast. J. Clin. Pharmacol. 51, 751-760 (2011).
    • (2011) J. Clin. Pharmacol. , vol.51 , pp. 751-760
    • Mougey, E.B.1    Lang, J.E.2    Wen, X.3    Lima, J.J.4
  • 63
    • 14844363404 scopus 로고    scopus 로고
    • Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients
    • DOI 10.1161/01.CIR.0000156466.02908.ED
    • Gradman, A.H., Schmieder, R.E., Lins, R.L., Nussberger, J., Chiang, Y. & Bedigian, M.P. Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients. Circulation 111, 1012-1018 (2005). (Pubitemid 40354519)
    • (2005) Circulation , vol.111 , Issue.8 , pp. 1012-1018
    • Gradman, A.H.1    Schmieder, R.E.2    Lins, R.L.3    Nussberger, J.4    Chiang, Y.5    Bedigian, M.P.6
  • 64
    • 54049086657 scopus 로고    scopus 로고
    • Pharmacokinetics of the oral direct renin inhibitor aliskiren in combination with digoxin, atorvastatin, and ketoconazole in healthy subjects: The role of P-glycoprotein in the disposition of aliskiren
    • Vaidyanathan, S. et al. Pharmacokinetics of the oral direct renin inhibitor aliskiren in combination with digoxin, atorvastatin, and ketoconazole in healthy subjects: the role of P-glycoprotein in the disposition of aliskiren. J. Clin. Pharmacol. 48, 1323-1338 (2008).
    • (2008) J. Clin. Pharmacol. , vol.48 , pp. 1323-1338
    • Vaidyanathan, S.1
  • 65
    • 84864277039 scopus 로고    scopus 로고
    • Intestinal OATP1A2 inhibition as a potential mechanism for the effect of grapefruit juice on aliskiren pharmacokinetics in healthy subjects
    • Rebello, S. et al. Intestinal OATP1A2 inhibition as a potential mechanism for the effect of grapefruit juice on aliskiren pharmacokinetics in healthy subjects. Eur. J. Clin. Pharmacol. 68, 697-708 (2012).
    • (2012) Eur. J. Clin. Pharmacol. , vol.68 , pp. 697-708
    • Rebello, S.1
  • 66
  • 68
    • 77955925948 scopus 로고    scopus 로고
    • Grapefruit juice greatly reduces the plasma concentrations of the OATP2B1 and CYP3A4 substrate aliskiren
    • Tapaninen, T., Neuvonen, P.J. & Niemi, M. Grapefruit juice greatly reduces the plasma concentrations of the OATP2B1 and CYP3A4 substrate aliskiren. Clin. Pharmacol. Ther. 88, 339-342 (2010).
    • (2010) Clin. Pharmacol. Ther. , vol.88 , pp. 339-342
    • Tapaninen, T.1    Neuvonen, P.J.2    Niemi, M.3
  • 69
    • 28244461508 scopus 로고    scopus 로고
    • Effects of grapefruit juice on the pharmacokinetics of acebutolol
    • DOI 10.1111/j.1365-2125.2005.02489.x
    • Lilja, J.J., Raaska, K. & Neuvonen, P.J. Effects of grapefruit juice on the pharmacokinetics of acebutolol. Br. J. Clin. Pharmacol. 60, 659-663 (2005). (Pubitemid 41705387)
    • (2005) British Journal of Clinical Pharmacology , vol.60 , Issue.6 , pp. 659-663
    • Lilja, J.J.1    Raaska, K.2    Neuvonen, P.3
  • 70
    • 34248545606 scopus 로고    scopus 로고
    • Effects of clarithromycin and grapefruit juice on the pharmacokinetics of glibenclamide
    • DOI 10.1111/j.1365-2125.2006.02836.x
    • Lilja, J.J., Niemi, M., Fredrikson, H. & Neuvonen, P.J. Effects of clarithromycin and grapefruit juice on the pharmacokinetics of glibenclamide. Br. J. Clin. Pharmacol. 63, 732-740 (2007). (Pubitemid 46753573)
    • (2007) British Journal of Clinical Pharmacology , vol.63 , Issue.6 , pp. 732-740
    • Lilja, J.J.1    Niemi, M.2    Fredrikson, H.3    Neuvonen, P.J.4
  • 71
    • 0348112532 scopus 로고    scopus 로고
    • Lack of bioequivalence when levofloxacin and calcium-fortified orange juice are coadministered to healthy volunteers
    • Wallace, A.W., Victory, J.M. & Amsden, G.W. Lack of bioequivalence when levofloxacin and calcium-fortified orange juice are coadministered to healthy volunteers. J. Clin. Pharmacol. 43, 539-544 (2003). (Pubitemid 36506155)
    • (2003) Journal of Clinical Pharmacology , vol.43 , Issue.5 , pp. 539-544
    • Wallace, A.W.1    Victory, J.M.2    Amsden, G.W.3
  • 72
    • 24044433942 scopus 로고    scopus 로고
    • Effects of grapefruit juice on the absorption of levothyroxine
    • DOI 10.1111/j.1365-2125.2005.02433.x
    • Lilja, J.J., Laitinen, K. & Neuvonen, P.J. Effects of grapefruit juice on the absorption of levothyroxine. Br. J. Clin. Pharmacol. 60, 337-341 (2005). (Pubitemid 41224144)
    • (2005) British Journal of Clinical Pharmacology , vol.60 , Issue.3 , pp. 337-341
    • Lilja, J.J.1    Laitinen, K.2    Neuvonen, P.J.3
  • 74
    • 0242645646 scopus 로고    scopus 로고
    • Grapefruit juice increases serum concentrations of atorvastatin and has no effect on pravastatin
    • Lilja, J.J., Kivistö, K.T. & Neuvonen, P.J. Grapefruit juice increases serum concentrations of atorvastatin and has no effect on pravastatin. Clin. Pharmacol. Ther. 66, 118-127 (1999). (Pubitemid 29398847)
    • (1999) Clinical Pharmacology and Therapeutics , vol.66 , Issue.2 , pp. 118-127
    • Lilja, J.J.1    Kivisto, K.T.2    Neuvonen, P.J.3
  • 75
    • 1942423683 scopus 로고    scopus 로고
    • Effects of grapefruit juice on pharmacokinetics of atorvastatin and pravastatin in Japanese
    • DOI 10.1046/j.1365-2125.2003.02030.x
    • Fukazawa, I., Uchida, N., Uchida, E. & Yasuhara, H. Effects of grapefruit juice on pharmacokinetics of atorvastatin and pravastatin in Japanese. Br. J. Clin. Pharmacol. 57, 448-455 (2004). (Pubitemid 38519650)
    • (2004) British Journal of Clinical Pharmacology , vol.57 , Issue.4 , pp. 448-455
    • Fukazawa, I.1    Uchida, N.2    Uchida, E.3    Yasuhara, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.