Effects of orange juice on the pharmacokinetics of atenolol

European Journal of Clinical Pharmacology

Volumn 61, Issue 5-6, 2005, Pages 337-340

  Lilja, J J ^a   Raaska, K ^a   Neuvonen, P J ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Atenolol; Bioavailability; Food drug interaction; Orange juice

Indexed keywords

ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT;

ADULT; AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIASTOLIC BLOOD PRESSURE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG ELIMINATION; DRUG EXCRETION; DRUG HALF LIFE; DRUG MECHANISM; FOOD DRUG INTERACTION; HEART RATE; HUMAN; KIDNEY CLEARANCE; MALE; ORANGE JUICE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SYSTOLIC BLOOD PRESSURE;

ADRENERGIC BETA-ANTAGONISTS; ADULT; AREA UNDER CURVE; ATENOLOL; BEVERAGES; BIOLOGICAL AVAILABILITY; BLOOD PRESSURE; CITRUS SINENSIS; CROSS-OVER STUDIES; FEMALE; FOOD-DRUG INTERACTIONS; HALF-LIFE; HEART RATE; HUMANS; MALE; METABOLIC CLEARANCE RATE;

EID: 27644463532     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-005-0930-9     Document Type: Article

References (22)

1. Bailey DG, Spence JD, Munoz C, Arnold JMO (1991) Interaction of citrus juices with felodipine and nifedipine. Lancet 337:268-269
2. Kantola T, Kivistö KT, Neuvonen PJ (1998) Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid. Clin Pharmacol Ther 63:397-402
3. Lilja JJ, Kivistö KT, Neuvonen PJ (1998) Grapefruit juice-simvastatin interaction: effect on serum concentrations of simvastatin, simvastatin acid, and HMG-CoA reductase inhibitors. Clin Pharmacol Ther 64:477-483
4. Kivistö KT, Lilja JJ, Backman JT, Neuvonen PJ (1999) Repeated consumption of grapefruit juice considerably increases plasma concentrations of cisapride. Clin Pharmacol Ther 66:448-453
5. Hukkinen SK, Varhe A, Olkkola KT, Neuvonen PJ (1995) Plasma concentrations of triazolam are increased by concomitant ingestion of grapefruit juice. Clin Pharmacol Ther 58:127-131
6. Lilja JJ, Kivistö KT, Backman JT, Lamberg TS, Neuvonen PJ (1998) Grapefruit juice substantially increases plasma concentrations of buspirone. Clin Pharmacol Ther 64:655-660
7. Jetter A, Kinzig-Schippers M, Walchner-Bonjean M, Hering U, Bulitta J, Schreiner P, Sorgel F, Fuhr U (2002) Effects of grapefruit juice on the pharmacokinetics of sildenafil. Clin Pharmacol Ther 71:21-29
8. Lown KS, Bailey DG, Fontana RJ, Janardan SK, Adair CH, Fortlage LA, Brown MB, Guo W, Watkins PB (1997) Grape-fruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression. J Clin Invest 99:2545-2553
9. Dresser GK, Bailey DG, Leake BF, Schwarz UI, Dawson PA, Freeman DJ, Kim RB (2002) Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine. Clin Pharmacol Ther 71:11-20
10. Lilja JJ, Backman JT, Laitila J, Luurila H, Neuvonen PJ (2003) Itraconazole increases but grapefruit juice greatly decreases plasma concentrations of celiprolol. Clin Pharmacol Ther 73:192-198
11. Lilja JJ, Juntti-Patinen L, Neuvonen PJ (2004) Orange juice substantially reduces the bioavailability of the beta-adrenergic-blocking agent celiprolol. Clin Pharmacol Ther 75:184-190
12. Dollery C (ed) (1999) Therapeutic drugs, vol 1. Churchill Livingstone, Edinburgh, UK, pp A224-A227
13. Wan SH, Koda RT, Maronde RF (1979) Pharmacokinetics, pharmacology of atenolol and effect of renal disease. Br J Clin Pharmacol 7:569-574
14. Karlsson J, Kuo S-M, Ziemniak J, Artursson P (1993) Transport of celiprolol across human intestinal epithelial (Caco-2) cells: mediation of secretion by multiple transporters including P-glycoprotein. Br J Pharmacol 110:1009-1016
15. Läer S, Wauer I, Scholz H (2001) Small blood volumes from children for quantitative sotalol determination using high-performance liquid chromatography. J Chromatogr B Biomed Sci Appl 753:421-425
16. Yee GC, Stanley DL, Pessa LJ, Dalla Costa T, Beltz SE, Ruiz J, Lowenthal DT (1995) Effect of grapefruit juice on blood cyclosporin concentration. Lancet 345:955-956
17. Artursson P (1990) Epithelial transport of drugs in cell culture. I: a model for studying the passive diffusion of drugs over intestinal absorptive (Caco-2) cells. J Pharm Sci 79:476-482
18. Lennernäs H, Ahrenstedt Ö, Ungell A-L (1994) Intestinal drug absorption during induced net water absorption in man; a mechanistic study using antipyrine, atenolol and enalaprilat. Br J Clin Pharmacol 37:589-596
19. Melander A, Stenberg P, Liedholm H, Scherstén B, Wåhlin-Boll E (1979) Food-induced reduction in bioavailability of atenolol. Eur J Clin Pharmacol 16:327-330
20. Barnwell SG, Laudanski T, Dwyer M, Story MJ, Guard P, Cole S, Attwood D (1993) Reduced bioavailability of atenolol in man: the role of bile acids. Int J Pharm 89:245-250
21. Yamaguchi T, Ikeda C, Sekine Y (1986) Intestinal absorption of a beta-adrenergic blocking agent nadolol. II. Mechanism of the inhibitory effect on the intestinal absorption of nadolol by sodium cholate in rats. Chem Pharm Bull 34:3836-3843
22. Yamaguchi T, Oida T, Ikeda C (1986) Intestinal absorption of a beta-adrenergic blocking agent nadolol. III. Nuclear magnetic resonance spectroscopic study on nadolol-sodium cholate micellar complex and intestinal absorption of nadolol derivatives in rats. Chem Pharm Bull 34:4259-4264