메뉴 건너뛰기




Volumn 63, Issue 3, 2011, Pages 435-443

Modulation of P-glycoprotein-mediated anticancer drug accumulation, cytotoxicity, and ATPase activity by flavonoid interactions

Author keywords

[No Author keywords available]

Indexed keywords

4 ,7 DIMETHOXYFLAVONE; 4',6', 7 TRIACETOXYISOFLAVONE; 4',6,7 TRIMETHOXYISOFLAVONE; 4',7 DIHYDROXYFLAVONE; 4',7 DIMETHOXYISOFLAVONE; ABC TRANSPORTER; ACACETIN; ADENOSINE TRIPHOSPHATASE; APIGENIN; BIOCHANIN A; CHRYSIN; CIRSIMARITIN; COLCHICINE; DAIDZEIN; DAUNORUBICIN; FLAVONE; FLAVONOID; GENISTEIN; GLYCOPROTEIN P; HESPERIDIN; NARINGENIN; OSAJIN; PSI BAPTIGENIN ACETATE; QUERCETIN; QUERCITRIN; RUTOSIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VERAPAMIL; VINBLASTINE; VITEXIN;

EID: 79957551963     PISSN: 01635581     EISSN: 15327914     Source Type: Journal    
DOI: 10.1080/01635581.2011.535959     Document Type: Article
Times cited : (37)

References (54)
  • 1
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Role of ATP-dependent transporters
    • Gottesman MM, Fojo T, and Bates SE: Multidrug resistance in cancer: role of ATP-dependent transporters. Nat Rev Cancer 2, 48-58, 2002. (Pubitemid 37328807)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.1 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 2
    • 0033179095 scopus 로고    scopus 로고
    • Frequency and clinical significance of the expression of the multidrug resistance proteins MDR1/P-glycoprotein, MRP1, and LRP in acute myeloid leukemia. A Southwest Oncology Group study
    • Leith C, Kopecky K, Chen I, Eijdems L, Slovak M, et al.: Frequency and clinical significance of the expression of the multidrug resistance proteins MDR1/P-glycoprotein, MRP1, and LRP in acute myeloid leukemia. A Southwest Oncology Group study. Blood 94, 1086-1099, 1999.
    • (1999) Blood , vol.94 , pp. 1086-1099
    • Leith, C.1    Kopecky, K.2    Chen, I.3    Eijdems, L.4    Slovak, M.5
  • 3
    • 0027314191 scopus 로고
    • Expression of the multidrug resistance-associated P-glycoprotein (P-170) in 59 cases of de novo acute lymphoblastic leukemia: Prognostic implications
    • Goasguen JE, Dossot J-M, Fardel O, LeMee F, Le Gall E, et al.: Expression of the multidrug resistance-associated P-glycoprotein (P-170) in 59 cases of de novo acute lymphoblastic leukemia: prognostic implications. Blood 81, 2394-2398, 1993. (Pubitemid 23127076)
    • (1993) Blood , vol.81 , Issue.9 , pp. 2394-2398
    • Goasguen, J.E.1    Dossot, J.-M.2    Fardel, O.3    Le, M.F.4    Le, G.E.5    Leblay, R.6    LePrise, P.Y.7    Chaperon, J.8    Fauchet, R.9
  • 4
    • 0025231784 scopus 로고
    • Immunohistochemical detection of P-glycoprotein: Prognostic correlation in soft tissue sarcoma of childhood
    • Chan HSL, Thorner PS, Haddad G, and Ling V: Immunohistochemical detection of P-glycoprotein: prognostic correlation in soft tissue sarcoma of childhood. J Clin Oncol 8, 689-704, 1990. (Pubitemid 20127254)
    • (1990) Journal of Clinical Oncology , vol.8 , Issue.4 , pp. 689-704
    • Chan, H.S.L.1    Thorner, P.S.2    Haddad, G.3    Ling, V.4
  • 5
    • 0025990960 scopus 로고
    • P-glycoprotein expression as a predictor of the outcome of therapy for neuroblastoma
    • Chan HSL, Haddad G, Thorner PS, DeBoer G, Lin YP, et al.: P-glycoprotein expression as a predictor of the outcome of therapy for neuroblastoma. N Engl J Med 325, 1608-1614, 1991.
    • (1991) N Engl J Med , vol.325 , pp. 1608-1614
    • Chan, H.S.L.1    Haddad, G.2    Thorner, P.S.3    DeBoer, G.4    Lin, Y.P.5
  • 6
    • 0028809430 scopus 로고
    • Expression of P-glycoprotein in high-grade osteosarcomas in relation to clinical outcome
    • Baldini N, Scotlandi K, Barbandi-Brodano G, Manara MC, Maurici D, et al.: Expression of P-glycoprotein in high-grade osteosarcomas in relation to clinical outcome. N Engl J Med 333, 1380-1385, 1995.
    • (1995) N Engl J Med , vol.333 , pp. 1380-1385
    • Baldini, N.1    Scotlandi, K.2    Barbandi-Brodano, G.3    Manara, M.C.4    Maurici, D.5
  • 7
    • 0029131093 scopus 로고
    • Prognostic relevance of P-glycoprotein expression in breast cancer
    • Linn SC, Giaccone G, van Diest PJ, et al.: Prognostic relevance of P-glycoprotein expression in breast cancer. Ann Oncol 6, 679-685, 1995.
    • (1995) Ann Oncol , vol.6 , pp. 679-685
    • Linn, S.C.1    Giaccone, G.2    Van Diest, P.J.3
  • 8
    • 0038813942 scopus 로고    scopus 로고
    • Modulation of p-glycoprotein (P-gp) mediated multidrug resistance (MDR) using chemosensitizers: Recent advances in the design of selective MDR modulators
    • Krishna R and Mayer LD: Modulation of p-glycoprotein (P-gp) mediated multidrug resistance (MDR) using chemosensitizers: recent advances in the design of selective MDR modulators. Curr Med Chem-Anti-Cancer Agents 1, 163-174, 2001.
    • (2001) Curr Med Chem-Anti-Cancer Agents , vol.1 , pp. 163-174
    • Krishna, R.1    Mayer, L.D.2
  • 10
    • 33750958329 scopus 로고    scopus 로고
    • New insights on the anticancer properties of dietary polyphenols
    • DOI 10.1002/med.20060
    • Fresco P, Borges F, Diniz C, and Marques MP: New insights on the anticancer properties of dietary polyphenols. Med Res Rev 26, 747-766, 2006. (Pubitemid 44735552)
    • (2006) Medicinal Research Reviews , vol.26 , Issue.6 , pp. 747-766
    • Fresco, P.1    Borges, F.2    Diniz, C.3    Marques, M.P.M.4
  • 12
    • 16344370794 scopus 로고    scopus 로고
    • Flavonoid compounds: A review of anticancer properties and interactions with cis-diamminedichloroplatinum(II)
    • DOI 10.1002/ddr.10421
    • Kosmider B and Osiecka R: Flavonoid compounds: a review of anticancer properties and interactions with cis-diamminedichloroplatinum(II). Drug Dev Res 63, 200-211, 2004. (Pubitemid 40470659)
    • (2004) Drug Development Research , vol.63 , Issue.4 , pp. 200-211
    • Kosmider, B.1    Osiecka, R.2
  • 13
    • 0036401813 scopus 로고    scopus 로고
    • Flavonoids as anticancer agents: Structure-activity relationship study
    • Lopez-Lazaro M: Flavonoids as anticancer agents: structure-activity relationship study. Curr Med Chem-Anti - Cancer Agents 2, 691-714, 2002.
    • (2002) Curr Med Chem-Anti - Cancer Agents , vol.2 , pp. 691-714
    • Lopez-Lazaro, M.1
  • 14
    • 0034349180 scopus 로고    scopus 로고
    • Flavonoids of leguminous plants: Structure, biological activity, and biosynthesis
    • Toshio A, Tomoyoshi A, and Shinichi A: Flavonoids of leguminous plants: structure, biological activity, and biosynthesis. J Plant Res 113, 475-48, 2000.
    • (2000) J Plant Res , vol.113 , pp. 475-548
    • Toshio, A.1    Tomoyoshi, A.2    Shinichi, A.3
  • 15
    • 0030240388 scopus 로고    scopus 로고
    • Relation between Intake of Flavonoids and Risk for Coronary Heart Disease in Male Health Professionals
    • Rimm EG, Katan MB, Ascherio A, Stampfer MJ, and Willett WC: Relation between intake of flavonoids and risk for coronary heart disease in male health professionals. Ann Intern Med 125, 384-389, 1996. (Pubitemid 126449708)
    • (1996) Annals of Internal Medicine , vol.125 , Issue.5 , pp. 384-389
    • Rimm, E.B.1    Katan, M.B.2    Ascherio, A.3    Stampfer, M.J.4    Willett, W.C.5
  • 16
    • 0036400016 scopus 로고    scopus 로고
    • Dietary flavonoids: Bioavailability, metabolic effects, and safety
    • DOI 10.1146/annurev.nutr.22.111401.144957
    • Ross JA and Kasum CM: Dietary flavonoids: bioavailability, metabolic effects, and safety. Ann Rev Nutr 22, 19-34, 2002. (Pubitemid 35221452)
    • (2002) Annual Review of Nutrition , vol.22 , pp. 19-34
    • Ross, J.A.1    Kasum, C.M.2
  • 17
    • 33747305858 scopus 로고    scopus 로고
    • Modulation of metabolic enzymes by dietary phytochemicals: A review of mechanisms underlying beneficial versus unfavorable effects
    • Mandlekar S, Hong JL, and Kong ANT: Modulation of metabolic enzymes by dietary phytochemicals: a review of mechanisms underlying beneficial versus unfavorable effects. Curr Drug Metab 7, 661-675, 2006.
    • (2006) Curr Drug Metab , vol.7 , pp. 661-675
    • Mandlekar, S.1    Hong, J.L.2    Kong, A.N.T.3
  • 18
    • 33644914487 scopus 로고    scopus 로고
    • Flavonoid-drug interactions: Effects of flavonoids on ABC transporters
    • Morris ME and Zhang S: Flavonoid-drug interactions: effects of flavonoids on ABC transporters. Life Sci 78, 2116-2130, 2006.
    • (2006) Life Sci , vol.78 , pp. 2116-2130
    • Morris, M.E.1    Zhang, S.2
  • 19
    • 0030782511 scopus 로고    scopus 로고
    • Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities
    • Shapiro AB and Ling V: Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities. Eur J Biochem 250, 130-137, 1997. (Pubitemid 27504592)
    • (1997) European Journal of Biochemistry , vol.250 , Issue.1 , pp. 130-137
    • Shapiro, A.B.1    Ling, V.2
  • 20
    • 0032544087 scopus 로고    scopus 로고
    • Flavonoids: A class of modulators with bifunctional interactions at vicinal ATP- And steroid-binding sites on mouse P-glycoprotein
    • Conseil G, Baubichon-Cortay H, Dayan G, Jault JM, Barron D, et al.: Flavonoids: a class of modulators with bifunctional interactions at vicinal ATP- and steroid-binding sites on mouse P-glycoprotein. Proc Natl Acad Sci USA 95, 9831-9836, 1998.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9831-9836
    • Conseil, G.1    Baubichon-Cortay, H.2    Dayan, G.3    Jault, J.M.4    Barron, D.5
  • 21
    • 0031060647 scopus 로고    scopus 로고
    • Inhibition of drug transport by genistein in multidrug-resistant cells expressing P-glycoprotein
    • DOI 10.1016/S0006-2952(96)00657-0, PII S0006295296006570
    • Castro AF and Altenberg GA: Inhibition of drug transport by genistein in multidrug-resistant cells expressing P-glycoprotein. Biochem Pharmacol 53, 89-93, 1997. (Pubitemid 26419790)
    • (1997) Biochemical Pharmacology , vol.53 , Issue.1 , pp. 89-93
    • Castro, A.F.1    Altenberg, G.A.2
  • 22
    • 0345491352 scopus 로고    scopus 로고
    • Flavonoid-related modulators of multidrug resistance: Synthesis, pharmacological activity, and structure-activity relationships
    • Ferte J, Kuhnel JM, Chapius G, Rolland Y, Lewin G, et al.: Flavonoid-related modulators of multidrug resistance: synthesis, pharmacological activity, and structure-activity relationships. J Med Chem 42, 478-489, 1999.
    • (1999) J Med Chem , vol.42 , pp. 478-489
    • Ferte, J.1    Kuhnel, J.M.2    Chapius, G.3    Rolland, Y.4    Lewin, G.5
  • 23
    • 0028172728 scopus 로고
    • Modulation of adriamycin accumulation and efflux by flavonoids in HCT-15 colon cells: Activation of P-glycoprotein as a putative mechanism
    • Critchfield JW, Welsh CJ, Phang JM, and Yeh GC: Modulation of adriamycin accumulation and efflux by flavonoids in HCT-15 colon cells: activation of P-glycoprotein as a putative mechanism. Biochem Pharmacol 48, 1437-1445, 1994.
    • (1994) Biochem Pharmacol , vol.48 , pp. 1437-1445
    • Critchfield, J.W.1    Welsh, C.J.2    Phang, J.M.3    Yeh, G.C.4
  • 24
    • 0027132062 scopus 로고
    • Flavonol-stimulated efflux of 7,12-dimethylbenz(a)anthracene in multidrug- resistant breast cancer cells
    • Phang JM, Poore CM, Lopaczynska J, and Yeh GC: Flavonol - stimulated efflux of 7,12-dimethylbenz(a)anthracene inmultidrug-resistant breast cancer cells. Cancer Res 15, 5977-5981, 1993. (Pubitemid 24006169)
    • (1993) Cancer Research , vol.53 , Issue.24 , pp. 5977-5981
    • Phang, J.M.1    Poore, C.M.2    Lopaczynska, J.3    Grace, C.Y.4
  • 25
    • 0035556276 scopus 로고    scopus 로고
    • Selective modulation of P-glycoprotein-mediated drug resistance
    • Bebawy M, Morris MB, and Roufogalis BD: Selective modulation of P-glycoprotein-mediated drug resistance. Br J Cancer 85, 1998-2003, 2001.
    • (2001) Br J Cancer , vol.85 , pp. 1998-2003
    • Bebawy, M.1    Morris, M.B.2    Roufogalis, B.D.3
  • 26
    • 0031815188 scopus 로고    scopus 로고
    • Reversal of vinblastine transport by chlorpromazine in membrane vesicles from multidrug-resistant human CCRF-CEM leukaemia cells
    • Syed SK, Christopherson RI, and Roufogalis BD: Reversal of vinblastine transport by chlorpromazine inmembrane vesicles from multidrug-resistant human CCRF-CEM leukaemia cells. Br J Cancer 78, 321-327, 1998. (Pubitemid 28336417)
    • (1998) British Journal of Cancer , vol.78 , Issue.3 , pp. 321-327
    • Syed, S.K.1    Christopherson, R.I.2    Roufogalis, B.D.3
  • 28
    • 38849208598 scopus 로고    scopus 로고
    • Differential pharmacological regulation of drug efflux and pharmacoresistant schizophrenia
    • DOI 10.1002/bies.20706
    • Bebawy M and Chetty M: Differential pharmacological regulation of drug efflux and pharmacoresistant schizophrenia. Bioessays 30, 183-188, 2008. (Pubitemid 351196953)
    • (2008) BioEssays , vol.30 , Issue.2 , pp. 183-188
    • Bebawy, M.1    Chetty, M.2
  • 29
    • 85026737771 scopus 로고    scopus 로고
    • Flavonoids in foods
    • Anderson OM and Markham KR (eds.). Boca Raton, FL: CRC Press, Taylor & Francis Group
    • Kyle JAM and Duthie GG: Flavonoids in foods. In: Flavonoids, Chemistry, Biochemistry, and Applications, Anderson OM and Markham KR (eds.). Boca Raton, FL: CRC Press, Taylor & Francis Group, 2006, pp. 219-262.
    • (2006) Flavonoids, Chemistry, Biochemistry, and Applications , pp. 219-262
    • Kyle, J.A.M.1    Duthie, G.G.2
  • 30
    • 68949122548 scopus 로고    scopus 로고
    • Antiproliforative effects of honey and of its polyphenol: A review
    • Article ID 830616
    • Jaganathan SK and Mandal M: Antiproliforative effects of honey and of its polyphenol: a review. J Biomed Biotechnol 2009; Article ID 830616.
    • (2009) J Biomed Biotechnol
    • Jaganathan, S.K.1    Mandal, M.2
  • 31
    • 76849086566 scopus 로고    scopus 로고
    • Phenolic characterization of Northeast Portuguese propolis: Usual and unusual compounds
    • Falcao SI, Vilas-Boas M, Estevinho LM, Barros C, Domingues MR, et al.: Phenolic characterization of Northeast Portuguese propolis: usual and unusual compounds. Anal Bioanal Chem 396, 887-897, 2010.
    • (2010) Anal Bioanal Chem , vol.396 , pp. 887-897
    • Falcao, S.I.1    Vilas-Boas, M.2    Estevinho, L.M.3    Barros, C.4    Domingues, M.R.5
  • 33
    • 64749097275 scopus 로고    scopus 로고
    • Isolation and characterization of osajin and pomiferin: Discovery laboratory exercises for organic chemistry
    • Whaley WL, Rummel JD, Zemenu E, Li W, Yang P, et al.: Isolation and characterization of osajin and pomiferin: discovery laboratory exercises for organic chemistry. Chemical Educator 12, 179-184, 2007.
    • (2007) Chemical Educator , vol.12 , pp. 179-184
    • Whaley, W.L.1    Rummel, J.D.2    Zemenu, E.3    Li, W.4    Yang, P.5
  • 34
    • 0009966526 scopus 로고
    • The identification of twenty-three 5-deoxy and 10-5-hydroxy flavanoid from Baptisia lecontei (Leguminaceae)
    • Markham KR and Mabry TJ: The identification of twenty-three 5-deoxy and 10-5-hydroxy flavanoid from Baptisia lecontei (Leguminaceae). Phytochem 7, 791-801, 1968.
    • (1968) Phytochem , vol.7 , pp. 791-801
    • Markham, K.R.1    Mabry, T.J.2
  • 35
    • 0033765536 scopus 로고    scopus 로고
    • Antigiardial activity of isoflavones from Dalbergia frutescens bark
    • Khan IA, Avery MA, Burrant CL, Goins DK, Mikell JR, et al.: Antigiardial activity of isoflavones from Dalbergia frutescens bark. J Nat Prod 63, 1414-1416, 2000.
    • (2000) J Nat Prod , vol.63 , pp. 1414-1416
    • Khan, I.A.1    Avery, M.A.2    Burrant, C.L.3    Goins, D.K.4    Mikell, J.R.5
  • 36
    • 0027300073 scopus 로고
    • Differentiation and multidrug resistance in response to drug treatment in the K562 human leukaemia cell line
    • Marks DC, Davey MW, Davey RA, and Kidman AD: Differentiation and multidrug resistance in response to drug treatment in the K562 human leukaemia cell line. Br J Haematol 84, 83-89, 1993. (Pubitemid 23158119)
    • (1993) British Journal of Haematology , vol.84 , Issue.1 , pp. 83-89
    • Marks, D.C.1    Davey, M.W.2    Davey, R.A.3    Kidman, A.D.4
  • 37
    • 0023898749 scopus 로고
    • Physical-chemical properties shared by compounds that modulate multidrug resistance in human leukemic cells
    • Zamora JM, Pearce HL, and Beck WT: Physical-chemical properties shared by compounds that modulate multidrug resistance in human leukemic cells. Mol Pharmacol 33, 454-62, 1988.
    • (1988) Mol Pharmacol , vol.33 , pp. 454-462
    • Zamora, J.M.1    Pearce, H.L.2    Beck, W.T.3
  • 38
    • 0037464458 scopus 로고    scopus 로고
    • Comparison of in vitro P-glycoprotein screening assays: Recommendations for their use in drug discovery
    • DOI 10.1021/jm021012t
    • Schwab D, Fischer H, Tabatabaei A, Poli S, and Huwyler J: Comparison of in vitro p-glycoprotein screening assays: recommendations for their use in drug discovery. J Med Chem 46, 1716-1725, 2003. (Pubitemid 36444224)
    • (2003) Journal of Medicinal Chemistry , vol.46 , Issue.9 , pp. 1716-1725
    • Schwab, D.1    Fischer, H.2    Tabatabaei, A.3    Poli, S.4    Huwyler, J.5
  • 39
    • 0030743356 scopus 로고    scopus 로고
    • Competitive, non-competitive and cooperative interactions between substrates of P-glycoproteins as measured by ATPase activity
    • DOI 10.1016/S0925-4439(97)00027-6, PII S0925443997000276
    • Litman T, Zeuthen T, Skovsgaard T, and Stein WD: Competitive, non-competitive, and cooperative interactions between substrates of P-glycoprotein as measured by its ATPase activity. Biochim Biophys Acta - Molecular Basis of Disease 1361, 169-176, 1997. (Pubitemid 27362090)
    • (1997) Biochimica et Biophysica Acta - Molecular Basis of Disease , vol.1361 , Issue.2 , pp. 169-176
    • Litman, T.1    Zeuthen, T.2    Skovsgaard, T.3    Stein, W.D.4
  • 40
    • 0033918159 scopus 로고    scopus 로고
    • Complementary/alternative medicine use in a comprehensive cancer center and the implications for oncology
    • Richardson MA, Sanders T, Palmer JL, Greisinger A, and Singletary SA: Complementary/alternative medicine use in a comprehensive cancer center and the implications for oncology. J Clin Oncol 18, 2505-2514, 2000. (Pubitemid 30432515)
    • (2000) Journal of Clinical Oncology , vol.18 , Issue.13 , pp. 2505-2514
    • Richardson, M.A.1    Sanders, T.2    Palmer, J.L.3    Greisinger, A.4    Singletary, S.E.5
  • 41
    • 0030221523 scopus 로고    scopus 로고
    • Comparison of drug accumulation in P-glycoprotein-expressing and MRP-expressing human leukaemia cells
    • DOI 10.1016/0145-2126(96)00023-9
    • Davey M, Hargrave R, and Davey R: Comparison of drug accumulation in P-glycoprotein-expressing and MRP-expressing human leukeamia cells. Leukemia Res 20, 657-664, 1996. (Pubitemid 26364746)
    • (1996) Leukemia Research , vol.20 , Issue.8 , pp. 657-664
    • Davey, M.W.1    Hargrave, R.M.2    Davey, R.A.3
  • 42
    • 0037371275 scopus 로고    scopus 로고
    • Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport
    • DOI 10.1124/jpet.102.044412
    • Zhang S and Morris ME: Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport. J Pharmacol Exp Ther 304, 1258-1267, 2003. (Pubitemid 36254439)
    • (2003) Journal of Pharmacology and Experimental Therapeutics , vol.304 , Issue.3 , pp. 1258-1267
    • Zhang, S.1    Morris, M.E.2
  • 43
    • 0037196568 scopus 로고    scopus 로고
    • Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols
    • Jodoin J, Demeule M, and Beliveau R: Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols. Biochim Biophys Acta 1542, 149-159, 2002.
    • (2002) Biochim Biophys Acta , vol.1542 , pp. 149-159
    • Jodoin, J.1    Demeule, M.2    Beliveau, R.3
  • 46
    • 53849146739 scopus 로고    scopus 로고
    • Pure dietary flavonoids quercetin and (-)-epicatechin augment nitric oxide products and reduce endothelin-1 acutely in healthy men
    • Loke WM, Hodgson JM, Proudfoot JM, McKinley AJ, Puddey IB, et al.: Pure dietary flavonoids quercetin and (-)-epicatechin augment nitric oxide products and reduce endothelin-1 acutely in healthy men. Am J Clin Nutr 88, 1018-1025, 2008.
    • (2008) Am J Clin Nutr , vol.88 , pp. 1018-1025
    • Loke, W.M.1    Hodgson, J.M.2    Proudfoot, J.M.3    McKinley, A.J.4    Puddey, I.B.5
  • 47
    • 0030976331 scopus 로고    scopus 로고
    • Phyto-oestrogens and Western diseases
    • Aldercreutz H and Mazur W: Phyto-oestrogens and Western diseases. Ann Med 29, 95-120, 1997.
    • (1997) Ann Med , vol.29 , pp. 95-120
    • Aldercreutz, H.1    Mazur, W.2
  • 49
    • 0035022576 scopus 로고    scopus 로고
    • Anti-genotoxicity of galangin as a cancer chemopreventive agent candidate
    • DOI 10.1016/S1383-5742(01)00054-0, PII S1383574201000540
    • Heo MY, Sohn SJ, and Au WW: Antigenotoxicity of galangin as a cancer chemopreventive agent candidate. Mut Res 488, 135-150, 2001. (Pubitemid 32436428)
    • (2001) Mutation Research - Reviews in Mutation Research , vol.488 , Issue.2 , pp. 135-150
    • Heo, M.Y.1    Sohn, S.J.2    Au, W.W.3
  • 51
    • 0021736054 scopus 로고
    • Evidence by in vivo and in vitro studies that binding of pycnogenols to elastin affects its rate of degradation by elastases
    • DOI 10.1016/0006-2952(84)90004-2
    • Tixier JM, Godeau G, Robert AM, and Hornebeck W: Evidence by in vivo and in vitro studies that binding of pycnogenols to elastin affects its rate of degradation by elastases. Biochem Pharmacol 33, 3933-3939, 1984. (Pubitemid 15135022)
    • (1984) Biochemical Pharmacology , vol.33 , Issue.24 , pp. 3933-3939
    • Tixier, J.M.1    Godeau, G.2    Robert, A.M.3    Hornebeck, W.4
  • 52
    • 0039552151 scopus 로고    scopus 로고
    • Correlation between the affinity of flavonoids binding to cytosolic site of Leishmania tropica multidrug trans-porter and their efficiency to revert parasite resistance to daunomycin
    • Perez-Victoria JM, Chiquero MJ, Conseil G, Dayan G, Di Pietro A, et al.: Correlation between the affinity of flavonoids binding to cytosolic site of Leishmania tropica multidrug trans-porter and their efficiency to revert parasite resistance to daunomycin. Biochem 38, 1736-1743, 1999.
    • (1999) Biochem , vol.38 , pp. 1736-1743
    • Perez-Victoria, J.M.1    Chiquero, M.J.2    Conseil, G.3    Dayan, G.4    Di Pietro, A.5
  • 54
    • 0034599915 scopus 로고    scopus 로고
    • Efficacies of tea components on doxorubicin induced antitumor activity and reversal of multidrug resistance
    • DOI 10.1016/S0378-4274(99)00290-8, PII S0378427499002908
    • Sadzuka Y, Sugiyama T, and Sonobe T: Efficacies of tea components on doxorubicin induced antitumor activity and reversal ofmultidrug resistance. Toxicol Lett 114, 155-162, 2000. (Pubitemid 30125452)
    • (2000) Toxicology Letters , vol.114 , Issue.1-3 , pp. 155-162
    • Sadzuka, Y.1    Sugiyama, T.2    Sonobe, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.