-
1
-
-
38049010515
-
Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease
-
Lovell MA, Markesbery WR (2007) Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease. Nucleic Acids Res 35, 7497-7504.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 7497-7504
-
-
Lovell, M.A.1
Markesbery, W.R.2
-
2
-
-
0034923434
-
Oxidative damage is the earliest event in Alzheimer disease
-
Nunomura A, Perry G, Aliev G, Hirai K, Takeda A, Balraj EK, Jones PK, Ghanbari H,Wataya T, Shimohama S, Chiba S, Atwood CS, Petersen RB, Smith MA (2001) Oxidative damage is the earliest event in Alzheimer disease. J Neuropathol Exp Neurol 60, 759-767.
-
(2001)
J Neuropathol Exp Neurol
, vol.60
, pp. 759-767
-
-
Nunomura, A.1
Perry, G.2
Aliev, G.3
Hirai, K.4
Takeda, A.5
Balraj, E.K.6
Jones, P.K.7
Ghanbari, H.8
Wataya, T.9
Shimohama, S.10
Chiba, S.11
Atwood, C.S.12
Petersen, R.B.13
Smith, M.A.14
-
3
-
-
0033397009
-
Neuronal rna oxidation in alzheimer's disease and down's syndrome
-
Nunomura A, Perry G, Hirai K, Aliev G, Takeda A, Chiba S, Smith MA (1999) Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome. Ann N Y Acad Sci 893, 362-364.
-
(1999)
Ann N y Acad Sci
, vol.893
, pp. 362-364
-
-
Nunomura, A.1
Perry, G.2
Hirai, K.3
Aliev, G.4
Takeda, A.5
Chiba, S.6
Smith, M.A.7
-
4
-
-
0038417076
-
The identification and characterization of oxidized rnas in alzheimer's disease
-
Shan X, Tashiro H, Lin CL (2003) The identification and characterization of oxidized RNAs in Alzheimer's disease. J Neurosci 23, 4913-4921.
-
(2003)
J Neurosci
, vol.23
, pp. 4913-4921
-
-
Shan, X.1
Tashiro, H.2
Lin, C.L.3
-
5
-
-
75149118997
-
Role of oxidative stress in the progression of Alzheimer's disease
-
Sultana R, Butterfield DA (2010) Role of oxidative stress in the progression of Alzheimer's disease. J Alzheimers Dis 19, 341-353.
-
(2010)
J Alzheimers Dis
, vol.19
, pp. 341-353
-
-
Sultana, R.1
Butterfield, D.A.2
-
6
-
-
0034834620
-
Increased oxidative stress in Alzheimer's disease as assessed with 4-hydroxynonenal but not malondialdehyde
-
McGarth LT, McGleenon BM, Brennan S, McColl D, McIlroy S, Passmore AP (2001) Increased oxidative stress in Alzheimer's disease as assessed with 4-hydroxynonenal but not malondialdehyde. Q J Med 94, 385-490.
-
(2001)
Q J Med
, vol.94
, pp. 385-490
-
-
McGarth, L.T.1
McGleenon, B.M.2
Brennan, S.3
McColl, D.4
McIlroy, S.5
Passmore, A.P.6
-
7
-
-
0035112495
-
Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures
-
Lovell MA, Xie C, Markesbery WR (2001) Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures. Neurobiol Aging 22, 187-194.
-
(2001)
Neurobiol Aging
, vol.22
, pp. 187-194
-
-
Lovell, M.A.1
Xie, C.2
Markesbery, W.R.3
-
8
-
-
0031980065
-
Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease
-
Markesbery WR, Lovell MA (1998) Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease. Neurobiol Aging 19, 33-36.
-
(1998)
Neurobiol Aging
, vol.19
, pp. 33-36
-
-
Markesbery, W.R.1
Lovell, M.A.2
-
9
-
-
33744935554
-
Increased levels of 4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's disease
-
Williams TI, Lynn BC, Markesbery WR, Lovell MA (2006) Increased levels of 4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's disease. Neurobiol Aging 27, 1094-1099.
-
(2006)
Neurobiol Aging
, vol.27
, pp. 1094-1099
-
-
Williams, T.I.1
Lynn, B.C.2
Markesbery, W.R.3
Lovell, M.A.4
-
10
-
-
77953690754
-
Preclinical Alzheimer disease: Brain oxidative stress, Abeta peptide and proteomics
-
Aluise CD, Robinson RA, Beckett TL, Murphy MP, Cai J, Pierce WM,Markesbery WR, Butterfield DA (2010) Preclinical Alzheimer disease: Brain oxidative stress, Abeta peptide and proteomics. Neurobiol Dis 39, 221-228.
-
(2010)
Neurobiol Dis
, vol.39
, pp. 221-228
-
-
Aluise, C.D.1
Robinson, R.A.2
Beckett, T.L.3
Murphy, M.P.4
Cai, J.5
Pierce, W.M.6
Markesbery, W.R.7
Butterfield, D.A.8
-
11
-
-
79951560784
-
Redox proteomics analysis of brains from subjects with amnestic mild cognitive impairment compared to brains from subjects with preclinical Alzheimer disease: Insights into memory loss in MCI
-
Aluise CD, Robinson RA, Cai J, Pierce WM, Markesbery WR, Butterfield DA (2011) Redox proteomics analysis of brains from subjects with amnestic mild cognitive impairment compared to brains from subjects with preclinical Alzheimer disease: Insights into memory loss in MCI. J Alzheimers Dis 23, 257-269.
-
(2011)
J Alzheimers Dis
, vol.23
, pp. 257-269
-
-
Aluise, C.D.1
Robinson, R.A.2
Cai, J.3
Pierce, W.M.4
Markesbery, W.R.5
Butterfield, D.A.6
-
12
-
-
77952672909
-
Increased levels of 4-hydroxynonenal and acrolein in the brain in preclinical Alzheimer disease
-
Bradley MA, Markesbery WR, Lovell MA (2010) Increased levels of 4-hydroxynonenal and acrolein in the brain in preclinical Alzheimer disease. Free Radic Biol Med 48, 1570-1576.
-
(2010)
Free Radic Biol Med
, vol.48
, pp. 1570-1576
-
-
Bradley, M.A.1
Markesbery, W.R.2
Lovell, M.A.3
-
13
-
-
84859510372
-
Elevated 4-hydroxyhexenal in Alzheimer's disease (AD) progression
-
Bradley MA, Xiong-Fister S, Markesbery WR, Lovell MA (2012) Elevated 4-hydroxyhexenal in Alzheimer's disease (AD) progression. Neurobiol Aging 33, 1034-1044.
-
(2012)
Neurobiol Aging
, vol.33
, pp. 1034-1044
-
-
Bradley, M.A.1
Xiong-Fister, S.2
Markesbery, W.R.3
Lovell, M.A.4
-
14
-
-
13244271257
-
F2-isoprostanes in Alzheimer and other neurodegenerative diseases
-
Montine TJ, Montine KS, McMahan W, Markesbery WR, Quinn JF, Morrow JD (2005) F2-isoprostanes in Alzheimer and other neurodegenerative diseases. Antioxid Redox Signal 7, 269-275.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 269-275
-
-
Montine, T.J.1
Montine, K.S.2
McMahan, W.3
Markesbery, W.R.4
Quinn, J.F.5
Morrow, J.D.6
-
15
-
-
57249095767
-
Lipid peroxidation of membrane phopholipids generates hydroxy-alkenals and oxidized phopholipids active in physiological and/or pathological conditions
-
Catala A (2009) Lipid peroxidation of membrane phopholipids generates hydroxy-alkenals and oxidized phopholipids active in physiological and/or pathological conditions. Chem Physics Lipids 157, 1-11.
-
(2009)
Chem Physics Lipids
, vol.157
, pp. 1-11
-
-
Catala, A.1
-
16
-
-
0025099678
-
4-hydroxhexenal: A lipid peroxidation product derived from oxidized docosahexaenoic acid
-
Van Kuijk FJ, Holte LL, Dratz EA (1990) 4-hydroxhexenal: A lipid peroxidation product derived from oxidized docosahexaenoic acid. Biochim Biophys Acta 1043, 116-118.
-
(1990)
Biochim Biophys Acta
, vol.1043
, pp. 116-118
-
-
Van Kuijk, F.J.1
Holte, L.L.2
Dratz, E.A.3
-
17
-
-
42149161725
-
Molecular mechanisms of the conjugated alpha, beta-unsaturated carbonyl derivatives: Relevance to neurotoxicity and neurodegenerative diseases
-
LoPachin RM, Barber DS, Gavin T (2008) Molecular mechanisms of the conjugated alpha, beta-unsaturated carbonyl derivatives: Relevance to neurotoxicity and neurodegenerative diseases. Toxicol Sci 104, 235-249.
-
(2008)
Toxicol Sci
, vol.104
, pp. 235-249
-
-
Lopachin, R.M.1
Barber, D.S.2
Gavin, T.3
-
18
-
-
70349492687
-
Molecular mechanisms of 4-hydroxy-2-nonenal and acrolein toxicity: Nucleophilic targets and adduct formation
-
LoPachin RM, Gavin T, Petersen DR, Barber DS (2009) Molecular mechanisms of 4-hydroxy-2-nonenal and acrolein toxicity: Nucleophilic targets and adduct formation. Chem Res Toxicol 22, 1499-1508.
-
(2009)
Chem Res Toxicol
, vol.22
, pp. 1499-1508
-
-
Lopachin, R.M.1
Gavin, T.2
Petersen, D.R.3
Barber, D.S.4
-
19
-
-
0035112495
-
Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures
-
Lovell MA, Xie C, Markesbery WR (2001) Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures. Neurobiol Aging 22, 187-194.
-
(2001)
Neurobiol Aging
, vol.22
, pp. 187-194
-
-
Lovell, M.A.1
Xie, C.2
Markesbery, W.R.3
-
20
-
-
0031028437
-
Immunohistochemical detection of 4-hydroxy-2-nonenal adducts in Alzheimer's disease is associated with inheritance of APOE4
-
Montine KS, Olson SJ, Amarnath V, Whetsell WO Jr, Graham DG, Montine TJ (1997) Immunohistochemical detection of 4-hydroxy-2-nonenal adducts in Alzheimer's disease is associated with inheritance of APOE4. Am J Pathol 150, 437-443.
-
(1997)
Am J Pathol
, vol.150
, pp. 437-443
-
-
Montine, K.S.1
Olson, S.J.2
Amarnath, V.3
Whetsell Jr., W.O.4
Graham, D.G.5
Montine, T.J.6
-
21
-
-
0030714092
-
Elevated 4-hydroxynonenal in ventricular fluid in Alzheimer's disease
-
Lovell MA, Ehmann WD, Mattson MP, Markesbery WR (1997) Elevated 4-hydroxynonenal in ventricular fluid in Alzheimer's disease. Neurobiol Aging 18, 457-461.
-
(1997)
Neurobiol Aging
, vol.18
, pp. 457-461
-
-
Lovell, M.A.1
Ehmann, W.D.2
Mattson, M.P.3
Markesbery, W.R.4
-
22
-
-
84859510372
-
Elevated 4-hydroxyhexenal in Alzheimer's disease (AD) progression
-
Bradley MA, Xiong-Fister S, Markesbery WR, Lovell MA (2012) Elevated 4-hydroxyhexenal in Alzheimer's disease (AD) progression. Neurobiol Aging 33, 1034-1044.
-
(2012)
Neurobiol Aging
, vol.33
, pp. 1034-1044
-
-
Bradley, M.A.1
Xiong-Fister, S.2
Markesbery, W.R.3
Lovell, M.A.4
-
23
-
-
0034667741
-
Acrolein, a product of lipid peroxidation, inhibits glucose and glutamate uptake in primary neuronal cultures
-
Lovell MA, Xie C, Markesbery WR (2000) Acrolein, a product of lipid peroxidation, inhibits glucose and glutamate uptake in primary neuronal cultures. Free Radic Biol Med 29, 714-720.
-
(2000)
Free Radic Biol Med
, vol.29
, pp. 714-720
-
-
Lovell, M.A.1
Xie, C.2
Markesbery, W.R.3
-
24
-
-
0031020476
-
A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide
-
Mark RJ, Lovell MA, Markesbery WR, Uchida K, Mattson MP (1997) A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide. J Neurochem 68, 255-264.
-
(1997)
J Neurochem
, vol.68
, pp. 255-264
-
-
Mark, R.J.1
Lovell, M.A.2
Markesbery, W.R.3
Uchida, K.4
Mattson, M.P.5
-
25
-
-
0030608841
-
17Beta-estradiol attenuates oxidative impairment of synaptic Na+/K+-ATPase activity, glucose transport, and glutamate transport induced by amyloid beta-peptide and iron
-
Keller JN, Germeyer A, Begley JG, Mattson MP (1997) 17Beta-estradiol attenuates oxidative impairment of synaptic Na+/K+-ATPase activity, glucose transport, and glutamate transport induced by amyloid beta-peptide and iron. J Neurosci Res 50, 522-530.
-
(1997)
J Neurosci Res
, vol.50
, pp. 522-530
-
-
Keller, J.N.1
Germeyer, A.2
Begley, J.G.3
Mattson, M.P.4
-
26
-
-
1342306400
-
Acrolein inhibits NADH-linked mitochondrial enzyme activity: Implications for Alzheimer's disease
-
Pocernich CB, Butterfield DA (2003) Acrolein inhibits NADH-linked mitochondrial enzyme activity: Implications for Alzheimer's disease. Neurotox Res 5, 515-520.
-
(2003)
Neurotox Res
, vol.5
, pp. 515-520
-
-
Pocernich, C.B.1
Butterfield, D.A.2
-
27
-
-
0030797336
-
4-Hydroxynonenal, a product of lipid peroxidation, inhibits dephosphorylation of the microtubule-associated protein tau
-
Mattson MP, Fu W, Waeg G, Uchida K (1997) 4-Hydroxynonenal, a product of lipid peroxidation, inhibits dephosphorylation of the microtubule-associated protein tau. Neuroreport 8, 2275-2281.
-
(1997)
Neuroreport
, vol.8
, pp. 2275-2281
-
-
Mattson, M.P.1
Fu, W.2
Waeg, G.3
Uchida, K.4
-
28
-
-
42449100496
-
Trans-4-hydroxy-2-hexenal is a neurotoxic product of docosahexaenoic (22:6; N-3) acid oxidation
-
Long EK, Murphy TC, Leiphon LJ,Watt J, MorrowJD, Milne GL, Howard JR, Picklo MJ Sr (2008) Trans-4-hydroxy-2-hexenal is a neurotoxic product of docosahexaenoic (22:6; n-3) acid oxidation. J Neurochem 105, 714-724.
-
(2008)
J Neurochem
, vol.105
, pp. 714-724
-
-
Long, E.K.1
Murphy, T.C.2
Leiphon, L.J.3
Watt, J.4
Morrow, J.D.5
Milne, G.L.6
Howard, J.R.7
Picklo Sr., M.J.8
-
29
-
-
73449134762
-
Ethanol withdrawal increases glutathione adducts of 4-hydroxy-2-hexenal but not 4-hydroxyl-2-nonenal in the rat cerebral cortex
-
Long EK, Rosenberger TA, PickloMJSr (2010) Ethanol withdrawal increases glutathione adducts of 4-hydroxy-2-hexenal but not 4-hydroxyl-2-nonenal in the rat cerebral cortex. Free Radic Biol Med 48, 384-390.
-
(2010)
Free Radic Biol Med
, vol.48
, pp. 384-390
-
-
Long, E.K.1
Rosenberger, T.A.2
Picklo Sr., M.J.3
-
30
-
-
0032988610
-
Mild cognitive impairment: Clinical characterization and outcome
-
Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Kokmen E (1999) Mild cognitive impairment: Clinical characterization and outcome. Arch Neurol 56, 303-308.
-
(1999)
Arch Neurol
, vol.56
, pp. 303-308
-
-
Petersen, R.C.1
Smith, G.E.2
Waring, S.C.3
Ivnik, R.J.4
Tangalos, E.G.5
Kokmen, E.6
-
31
-
-
0021271971
-
Clinical diagnosis of Alzheimer's disease: Report of the nincds-adrda work group under the auspices of department of health and human services task force on alzheimer's disease
-
McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34, 939-944.
-
(1984)
Neurology
, vol.34
, pp. 939-944
-
-
McKhann, G.1
Drachman, D.2
Folstein, M.3
Katzman, R.4
Price, D.5
Stadlan, E.M.6
-
32
-
-
30344469658
-
Neuropathologic substrate of mild cognitive impairment
-
Markesbery WR, Schmitt FA, Kryscio RJ, Davis DG, Smith CD, Wekstein DR (2006) Neuropathologic substrate of mild cognitive impairment. Arch Neurol 63, 38-46.
-
(2006)
Arch Neurol
, vol.63
, pp. 38-46
-
-
Markesbery, W.R.1
Schmitt, F.A.2
Kryscio, R.J.3
Davis, D.G.4
Smith, C.D.5
Wekstein, D.R.6
-
33
-
-
0030681215
-
-
National Institute on Aging and the Reagan Institute Working on Group Diagnostic Criteria for the Neuropathological Assessment of Alzheimer's disease. Consensus recommendations for the postmortem diagnosis of Alzheimer's disease
-
National Institute on Aging and the Reagan Institute Working on Group Diagnostic Criteria for the Neuropathological Assessment of Alzheimer's disease. Consensus recommendations for the postmortem diagnosis of Alzheimer's disease (1997). Neurobiol Aging 18, S1-S2.
-
(1997)
Neurobiol Aging
, vol.18
-
-
-
34
-
-
18444393054
-
Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation
-
Wiltfang J, Esselmann H, Bibl M, Smirnov A, Otto M, Paul S, Schmidt B, Klafki HW, Maler M, Dyrks T, Bienert M, Beyermann M, Ruther E, Kornhuber J (2002) Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation. J Neurochem 81, 481-496.
-
(2002)
J Neurochem
, vol.81
, pp. 481-496
-
-
Wiltfang, J.1
Esselmann, H.2
Bibl, M.3
Smirnov, A.4
Otto, M.5
Paul, S.6
Schmidt, B.7
Klafki, H.W.8
Maler, M.9
Dyrks, T.10
Bienert, M.11
Beyermann, M.12
Ruther, E.13
Kornhuber, J.14
-
35
-
-
0030754962
-
4-Hydroxynonenal, an aldehydic product of membrane lipid peroxidation, impairs glutamate transport and mitochondrial function in synaptosomes
-
Keller JN, Mark RJ, Bruce AJ, Blanc E, Rothstein JD, Uchida K, Waeg G, Mattson MP (1997) 4-Hydroxynonenal, an aldehydic product of membrane lipid peroxidation, impairs glutamate transport and mitochondrial function in synaptosomes. Neuroscience 80, 685-696.
-
(1997)
Neuroscience
, vol.80
, pp. 685-696
-
-
Keller, J.N.1
Mark, R.J.2
Bruce, A.J.3
Blanc, E.4
Rothstein, J.D.5
Uchida, K.6
Waeg, G.7
Mattson, M.P.8
-
36
-
-
0023221068
-
Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay
-
Koh JY, Choi DW (1987) Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay. J Neurosci Methods 20, 83-90.
-
(1987)
J Neurosci Methods
, vol.20
, pp. 83-90
-
-
Koh, J.Y.1
Choi, D.W.2
-
37
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 65, 55-63.
-
(1983)
J Immunol Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
38
-
-
0026482507
-
Astrocyte glutamate uptake during chemical hypoxia in vitro
-
SwansonRA(1992) Astrocyte glutamate uptake during chemical hypoxia in vitro. Neurosci Lett 147, 143-146.
-
(1992)
Neurosci Lett
, vol.147
, pp. 143-146
-
-
Swanson, R.A.1
-
39
-
-
0035200103
-
Endothelin-1 decreases glutamate uptake in primary cultured rat astrocytes
-
Leonova J, Thorlin T, Aberg ND, Eriksson PS, Ronnback L, Hansson E (2001) Endothelin-1 decreases glutamate uptake in primary cultured rat astrocytes. Am J Physiol 281, C1495-C1503.
-
(2001)
Am J Physiol
, vol.281
-
-
Leonova, J.1
Thorlin, T.2
Aberg, N.D.3
Eriksson, P.S.4
Ronnback, L.5
Hansson, E.6
-
40
-
-
34648843243
-
Pathologically activated therapeutics for neuroprotection
-
Lipton SA (2007) Pathologically activated therapeutics for neuroprotection. Nat Rev Neurosci 8, 803-808.
-
(2007)
Nat Rev Neurosci
, vol.8
, pp. 803-808
-
-
Lipton, S.A.1
-
41
-
-
51649106793
-
Loss of VGLUT1 and VGLUT2 in the prefrontal cortex is correlated with cognitive decline in Alzheimer disease
-
Kashani A, Lepicard E, Poirel O, Videau C, David JP, Fallet-Bianco C, Simon A, Delacourte A, Giros B, Epelbaum J, Betancur C, El Mestikawy S (2008) Loss of VGLUT1 and VGLUT2 in the prefrontal cortex is correlated with cognitive decline in Alzheimer disease. Neurobiol Aging 29, 1619-1630.
-
(2008)
Neurobiol Aging
, vol.29
, pp. 1619-1630
-
-
Kashani, A.1
Lepicard, E.2
Poirel, O.3
Videau, C.4
David, J.P.5
Fallet-Bianco, C.6
Simon, A.7
Delacourte, A.8
Giros, B.9
Epelbaum, J.10
Betancur, C.11
El Mestikawy, S.12
-
42
-
-
0034069313
-
Glutamate uptake is decreased in platelets from Alzheimer's disease patients
-
Ferrarese C, Begni B, Canevari C, Zoia C, Piolti R, Frigo M, Appollonio I, Frattola L (2000) Glutamate uptake is decreased in platelets from Alzheimer's disease patients. Ann Neurol 47, 641-643.
-
(2000)
Ann Neurol
, vol.47
, pp. 641-643
-
-
Ferrarese, C.1
Begni, B.2
Canevari, C.3
Zoia, C.4
Piolti, R.5
Frigo, M.6
Appollonio, I.7
Frattola, L.8
-
43
-
-
0035936606
-
Decreased platelet glutamate uptake in patients with amyotrophic lateral sclerosis
-
Ferrarese C, Sala G, Riva R, Begni B, Zoia C, Tremolizzo L, Galimberti G, Millul A, Bastone A, Mennini T, Balzarini C, Frattola L, Beghi E (2001) Decreased platelet glutamate uptake in patients with amyotrophic lateral sclerosis. Neurology 56, 270-272.
-
(2001)
Neurology
, vol.56
, pp. 270-272
-
-
Ferrarese, C.1
Sala, G.2
Riva, R.3
Begni, B.4
Zoia, C.5
Tremolizzo, L.6
Galimberti, G.7
Millul, A.8
Bastone, A.9
Mennini, T.10
Balzarini, C.11
Frattola, L.12
Beghi, E.13
-
44
-
-
33846217457
-
Transporters for L-glutamate: An update on their molecular pharmacology and pathological involvement
-
Beart PM, O'Shea RD (2007) Transporters for L-glutamate: An update on their molecular pharmacology and pathological involvement. Br J Pharmacol 150, 5-17.
-
(2007)
Br J Pharmacol
, vol.150
, pp. 5-17
-
-
Beart, P.M.1
O'Shea, R.D.2
-
45
-
-
0023253244
-
Sodium dependent D-[3H]aspartate binding in cerebral cortex in patients with Alzheimer's and Parkinson's diseases
-
Cross AJ, Slater P, Simpson M, Royston C, Deakin JF, Perry RH, Perry EK (1987) Sodium dependent D-[3H]aspartate binding in cerebral cortex in patients with Alzheimer's and Parkinson's diseases. Neurosci Lett 79, 213-217.
-
(1987)
Neurosci Lett
, vol.79
, pp. 213-217
-
-
Cross, A.J.1
Slater, P.2
Simpson, M.3
Royston, C.4
Deakin, J.F.5
Perry, R.H.6
Perry, E.K.7
-
46
-
-
0023270315
-
Region-specific loss of glutamate innervation in Alzheimer's disease
-
Hardy J, Cowburn R, Barton A, Reynolds G, Lofdahl E, O'Carroll AM, Wester P, Winblad B (1987) Region-specific loss of glutamate innervation in Alzheimer's disease. Neurosci Lett 73, 77-80.
-
(1987)
Neurosci Lett
, vol.73
, pp. 77-80
-
-
Hardy, J.1
Cowburn, R.2
Barton, A.3
Reynolds, G.4
Lofdahl, E.5
O'Carroll, A.M.6
Wester, P.7
Winblad, B.8
-
47
-
-
0036318856
-
Effects of estrogen treatment on glutamate uptake in cultured human astrocytes derived from cortex of Alzheimer's disease patients
-
Liang Z, Valla J, Sefidvash-Hockley S, Rogers J, Li R (2002) Effects of estrogen treatment on glutamate uptake in cultured human astrocytes derived from cortex of Alzheimer's disease patients. J Neurochem 80, 807-814.
-
(2002)
J Neurochem
, vol.80
, pp. 807-814
-
-
Liang, Z.1
Valla, J.2
Sefidvash-Hockley, S.3
Rogers, J.4
Li, R.5
-
48
-
-
79952899104
-
Glutamate transporter variants reduce glutamate uptake in Alzheimer's disease
-
Scott HA, Gebhardt FM, Mitrovic AD, Vandenberg RJ, Dodd PR (2011) Glutamate transporter variants reduce glutamate uptake in Alzheimer's disease. Neurobiol Aging 32, 553.e1-e11.
-
(2011)
Neurobiol Aging
, vol.32
, Issue.553
-
-
Scott, H.A.1
Gebhardt, F.M.2
Mitrovic, A.D.3
Vandenberg, R.J.4
Dodd, P.R.5
-
49
-
-
77954721991
-
Aberrant detergent-insoluble excitatory amino acid transporter 2 accumulates in Alzheimer disease
-
Woltjer RL, Duerson K, Fullmer JM, Mookherjee P, Ryan AM, Montine TJ, Kaye JA, Quinn JF, Silbert L, Erten-Lyons D, Leverenz JB, Bird TD, Pow DV, Tanaka K, Watson GS, Cook DG (2010) Aberrant detergent-insoluble excitatory amino acid transporter 2 accumulates in Alzheimer disease. J Neuropathol Exp Neurol 69, 667-676.
-
(2010)
J Neuropathol Exp Neurol
, vol.69
, pp. 667-676
-
-
Woltjer, R.L.1
Duerson, K.2
Fullmer, J.M.3
Mookherjee, P.4
Ryan, A.M.5
Montine, T.J.6
Kaye, J.A.7
Quinn, J.F.8
Silbert, L.9
Erten-Lyons, D.10
Leverenz, J.B.11
Bird, T.D.12
Pow, D.V.13
Tanaka, K.14
Watson, G.S.15
Cook, D.G.16
-
50
-
-
0033779559
-
Astrocyte glutamate transport: Review of properties, regulation, and physiological functions
-
Anderson CM, Swanson RA (2000) Astrocyte glutamate transport: Review of properties, regulation, and physiological functions. Glia 32, 1-14.
-
(2000)
Glia
, vol.32
, pp. 1-14
-
-
Anderson, C.M.1
Swanson, R.A.2
-
51
-
-
0027136017
-
A new family of neurotransmitter transporters: The high-affinity glutamate transporters
-
Kanai Y, Smith CP, Hediger MA (1993) A new family of neurotransmitter transporters: The high-affinity glutamate transporters. FASEB J 7, 1450-1459.
-
(1993)
FASEB J.
, vol.7
, pp. 1450-1459
-
-
Kanai, Y.1
Smith, C.P.2
Hediger, M.A.3
-
52
-
-
0035001341
-
Glutamate uptake
-
Danbolt NC (2001) Glutamate uptake. Prog Neurobiol 65, 1-105.
-
(2001)
Prog Neurobiol
, vol.65
, pp. 1-105
-
-
Danbolt, N.C.1
-
53
-
-
54549086447
-
A quantitative assessment of glutamate uptake into hippocampal synaptic terminals and astrocytes: New insights into a neuronal role for excitatory amino acid transporter 2 (EAAT2
-
Furness DN, Dehnes Y, Akhtar AQ, Rossi DJ, Hamann M, Grutle NJ, Gundersen V, Holmseth S, Lehre KP, Ullensvang K,Wojewodzic M, Zhou Y, Attwell D, Danbolt NC (2008) A quantitative assessment of glutamate uptake into hippocampal synaptic terminals and astrocytes: New insights into a neuronal role for excitatory amino acid transporter 2 (EAAT2). Neuroscience 157, 80-94.
-
(2008)
Neuroscience
, vol.157
, pp. 80-94
-
-
Furness, D.N.1
Dehnes, Y.2
Akhtar, A.Q.3
Rossi, D.J.4
Hamann, M.5
Grutle, N.J.6
Gundersen, V.7
Holmseth, S.8
Lehre, K.P.9
Ullensvang, K.10
Wojewodzic, M.11
Zhou, Y.12
Attwell, D.13
Danbolt, N.C.14
-
54
-
-
0032194950
-
The number of glutamate transporter subtype molecules at glutamatergic synapses: Chemical and stereological quantification in young adult rat brain
-
Lehre KP, Danbolt NC (1998) The number of glutamate transporter subtype molecules at glutamatergic synapses: Chemical and stereological quantification in young adult rat brain. J Neurosci 18, 8751-8757.
-
(1998)
J Neurosci
, vol.18
, pp. 8751-8757
-
-
Lehre, K.P.1
Danbolt, N.C.2
-
55
-
-
34848821581
-
Extracellular glutamate concentration in hippocampal slice
-
Herman MA, Jahr CE (2007) Extracellular glutamate concentration in hippocampal slice. J Neurosci 27, 9736-9741.
-
(2007)
J Neurosci
, vol.27
, pp. 9736-9741
-
-
Herman, M.A.1
Jahr, C.E.2
-
56
-
-
70350454809
-
Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling
-
Abdul HM, Sama MA, Furman JL, Mathis DM, Beckett TL, Weidner AM, Patel ES, Baig I, Murphy MP, LeVine H 3rd, Kraner SD, Norris CM (2009) Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling. J Neurosci 29, 12957-12969.
-
(2009)
J Neurosci
, vol.29
, pp. 12957-12969
-
-
Abdul, H.M.1
Sama, M.A.2
Furman, J.L.3
Mathis, D.M.4
Beckett, T.L.5
Weidner, A.M.6
Patel, E.S.7
Baig, I.8
Murphy, M.P.9
LeVine III, H.10
Kraner, S.D.11
Norris, C.M.12
-
57
-
-
33847725506
-
Alterations in expression of glutamatergic transporters and receptors in sporadic Alzheimer's disease
-
Jacob CP, Koutsilieri E, Bartl J, Neuen-Jacob E, Arzberger T, Zander N, Ravid R, Roggendorf W, Riederer P, Grunblatt E (2007) Alterations in expression of glutamatergic transporters and receptors in sporadic Alzheimer's disease. J Alzheimers Dis 11, 97-116.
-
(2007)
J Alzheimers Dis
, vol.11
, pp. 97-116
-
-
Jacob, C.P.1
Koutsilieri, E.2
Bartl, J.3
Neuen-Jacob, E.4
Arzberger, T.5
Zander, N.6
Ravid, R.7
Roggendorf, W.8
Riederer, P.9
Grunblatt, E.10
-
58
-
-
0029811226
-
Deficient glutamate transport is associated with neurodegeneration in Alzheimer's disease
-
Masliah E, Alford M, DeTeresa R, Mallory M, Hansen L (1996) Deficient glutamate transport is associated with neurodegeneration in Alzheimer's disease. Ann Neurol 40, 759-766.
-
(1996)
Ann Neurol
, vol.40
, pp. 759-766
-
-
Masliah, E.1
Alford, M.2
Deteresa, R.3
Mallory, M.4
Hansen, L.5
-
59
-
-
0030872412
-
Glutamate transporter alterations in Alzheimer disease are possibly associated with abnormal APP expression
-
Li S, Mallory M, Alford M,Tanaka S, MasliahE(1997) Glutamate transporter alterations in Alzheimer disease are possibly associated with abnormal APP expression. J Neuropathol Exp Neurol 56, 901-911.
-
(1997)
J Neuropathol Exp Neurol
, vol.56
, pp. 901-911
-
-
Li, S.1
Mallory, M.2
Alford, M.3
Tanaka, S.4
Masliah, E.5
-
60
-
-
67649336238
-
Excitatory amino acid transporter 2 associates with phosphorylated tau and is localized in neurofibrillary tangles of tauopathic brains
-
Sasaki K, Shimura H, Itaya M, Tanaka R, Mori H, Mizuno Y, Kosik KS, Tanaka S, Hattori N (2009) Excitatory amino acid transporter 2 associates with phosphorylated tau and is localized in neurofibrillary tangles of tauopathic brains. FEBS Lett 583, 2194-2200.
-
(2009)
FEBS Lett
, vol.583
, pp. 2194-2200
-
-
Sasaki, K.1
Shimura, H.2
Itaya, M.3
Tanaka, R.4
Mori, H.5
Mizuno, Y.6
Kosik, K.S.7
Tanaka, S.8
Hattori, N.9
-
61
-
-
0033556396
-
Interindividual differences in the levels of the glutamate transporters GLAST and GLT, but no clear correlation with Alzheimer's disease
-
Beckstrom H, Julsrud L, Haugeto O, Dewar D, Graham DI, Lehre KP, Storm-Mathisen J, Danbolt NC (1999) Interindividual differences in the levels of the glutamate transporters GLAST and GLT, but no clear correlation with Alzheimer's disease. J Neurosci Res 55, 218-229.
-
(1999)
J Neurosci Res
, vol.55
, pp. 218-229
-
-
Beckstrom, H.1
Julsrud, L.2
Haugeto, O.3
Dewar, D.4
Graham, D.I.5
Lehre, K.P.6
Storm-Mathisen, J.7
Danbolt, N.C.8
-
62
-
-
1642371041
-
Altered expression of the glutamate transporter EAAT2b in neurological disease
-
Maragakis NJ, Dykes-HobergM, Rothstein JD (2004) Altered expression of the glutamate transporter EAAT2b in neurological disease. Ann Neurol 55, 469-477.
-
(2004)
Ann Neurol
, vol.55
, pp. 469-477
-
-
Maragakis, N.J.1
Dykes-Hoberg, M.2
Rothstein, J.D.3
-
63
-
-
0034088054
-
Beneficial effects of dietary restriction on cerebral cortical synaptic terminals: Preservation of glucose and glutamate transport and mitochondrial function after exposure to amyloid betapeptide, iron, and 3-nitropropionic acid
-
Guo Z, Ersoz A, Butterfield DA, Mattson MP (2000) Beneficial effects of dietary restriction on cerebral cortical synaptic terminals: Preservation of glucose and glutamate transport and mitochondrial function after exposure to amyloid betapeptide, iron, and 3-nitropropionic acid. J Neurochem 75, 314-320.
-
(2000)
J Neurochem
, vol.75
, pp. 314-320
-
-
Guo, Z.1
Ersoz, A.2
Butterfield, D.A.3
Mattson, M.P.4
-
64
-
-
0002639306
-
Neurotrophic factors protect cortical synaptic terminals against amyloid and oxidative stress-induced impairment of glucose transport, glutamate transport and mitochondrial function
-
Guo ZH, Mattson MP (2000) Neurotrophic factors protect cortical synaptic terminals against amyloid and oxidative stress-induced impairment of glucose transport, glutamate transport and mitochondrial function. Cereb Cortex 10, 50-57.
-
(2000)
Cereb Cortex
, vol.10
, pp. 50-57
-
-
Guo, Z.H.1
Mattson, M.P.2
-
65
-
-
0030966546
-
Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid beta-peptide: Role of the lipid peroxidation product 4-hydroxynonenal
-
Keller JN, Pang Z, Geddes JW, Begley JG, Germeyer A,Waeg G, Mattson MP (1997) Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid beta-peptide: Role of the lipid peroxidation product 4-hydroxynonenal. J Neurochem 69, 273-284.
-
(1997)
J Neurochem
, vol.69
, pp. 273-284
-
-
Keller, J.N.1
Pang, Z.2
Geddes, J.W.3
Begley, J.G.4
Germeyer, A.5
Waeg, G.6
Mattson, M.P.7
-
66
-
-
0034925118
-
The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: The role of Abeta1-42
-
Lauderback CM, Hackett JM, Huang FF, Keller JN, Szweda LI, Markesbery WR, Butterfield DA (2001) The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: The role of Abeta1-42. J Neurochem 78, 413-416.
-
(2001)
J Neurochem
, vol.78
, pp. 413-416
-
-
Lauderback, C.M.1
Hackett, J.M.2
Huang, F.F.3
Keller, J.N.4
Szweda, L.I.5
Markesbery, W.R.6
Butterfield, D.A.7
-
67
-
-
0028980414
-
Beta-Amyloid peptide-derived, oxygen-dependent free radicals inhibit glutamate uptake in cultured astrocytes: Implications for Alzheimer's disease
-
Harris ME, Carney JM, Cole PS, Hensley K, Howard BJ, Martin L, Bummer P, Wang Y, Pedigo NW Jr, Butterfield DA(1995) beta-Amyloid peptide-derived, oxygen-dependent free radicals inhibit glutamate uptake in cultured astrocytes: Implications for Alzheimer's disease. Neuroreport 6, 1875-1879.
-
(1995)
Neuroreport
, vol.6
, pp. 1875-1879
-
-
Harris, M.E.1
Carney, J.M.2
Cole, P.S.3
Hensley, K.4
Howard, B.J.5
Martin, L.6
Bummer, P.7
Wang, Y.8
Pedigo Jr., N.W.9
Butterfield, D.A.10
-
68
-
-
0029889640
-
Amyloid beta peptide (25-35) inhibits Na+-dependent glutamate uptake in rat hippocampal astrocyte cultures
-
Harris ME, Wang Y, Pedigo NW Jr, Hensley K, Butterfield DA, Carney JM(1996) Amyloid beta peptide (25-35) inhibits Na+-dependent glutamate uptake in rat hippocampal astrocyte cultures. J Neurochem 67, 277-286.
-
(1996)
J Neurochem
, vol.67
, pp. 277-286
-
-
Harris, M.E.1
Wang, Y.2
Pedigo Jr., N.W.3
Hensley, K.4
Butterfield, D.A.5
Carney, J.M.6
-
69
-
-
67249087641
-
Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake
-
Li S, Hong S, Shepardson NE, Walsh DM, Shankar GM, Selkoe D (2009) Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake. Neuron 62, 788-801.
-
(2009)
Neuron
, vol.62
, pp. 788-801
-
-
Li, S.1
Hong, S.2
Shepardson, N.E.3
Walsh, D.M.4
Shankar, G.M.5
Selkoe, D.6
-
70
-
-
4043050074
-
Oxidative stress impairs glutamate uptake in fibroblasts from patients with Alzheimer's disease
-
Begni B, Brighina L, Sirtori E, Fumagalli L, Andreoni S, Beretta S, Oster T, Malaplate-Armand C, Isella V, Appollonio I, Ferrarese C (2004) Oxidative stress impairs glutamate uptake in fibroblasts from patients with Alzheimer's disease. Free Radic Biol Med 37, 892-901.
-
(2004)
Free Radic Biol Med
, vol.37
, pp. 892-901
-
-
Begni, B.1
Brighina, L.2
Sirtori, E.3
Fumagalli, L.4
Andreoni, S.5
Beretta, S.6
Oster, T.7
Malaplate-Armand, C.8
Isella, V.9
Appollonio, I.10
Ferrarese, C.11
|