Aloe-emodin induces apoptosis of human nasopharyngeal carcinoma cells via caspase-8-mediated activation of the mitochondrial death pathway

Cancer Letters

Volumn 291, Issue 1, 2010, Pages 46-58

  Lin, Meng Liang ^a,b   Lu, Yao Cheng ^a   Chung, Jing Gung ^b   Li, Yi Chen ^c   Wang, Shyang Guang ^a   NG, Sue Hwee ^b   Wu, Chia Yin ^b   Su, Hong Lin ^d   Chen, Shih Shun ^a  

^a CENTRAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c LIN SHIN HOSPITAL   (Taiwan)

^d NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

Aloe emodin; Caspase 8; Mitochondrial death pathway; Nasopharyngeal carcinoma

Indexed keywords

ALOE EMODIN; APOPTOSIS INDUCING FACTOR; BENZYLOXYCARBONYLISOLEUCYLGLUTAMYLTHREONYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLLEUCYLGLUTAMYLHISTIDYLASPARTYL FLUOROMETHYL KETONE; CALCIUM ION; CASPASE 3; CASPASE 8; CASPASE 9; CELL CYCLE PROTEIN; CYCLIN B1; CYCLOSPORIN A; CYTOCHROME C; DNA; ENDONUCLEASE G; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID; PROTEIN CDC2; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL LEVEL; CELL STRUCTURE; CONTROLLED STUDY; DNA FRAGMENTATION; ENZYME ACTIVATION; ENZYME RELEASE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; NASOPHARYNX CARCINOMA; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ANTHRAQUINONES; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CASPASE 3; CASPASE 8; CELL CYCLE; CELL LINE, TUMOR; CYCLIN B; CYCLIN B1; HUMANS; MITOCHONDRIA; NASOPHARYNGEAL NEOPLASMS; REACTIVE OXYGEN SPECIES;

ALOE; RHEUM PALMATUM;

EID: 77950076456     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2009.09.016     Document Type: Article

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