Combination of arsenic trioxide and BCNU synergistically triggers redox-mediated autophagic cell death in human solid tumors

Free Radical Biology and Medicine

Volumn 51, Issue 12, 2011, Pages 2195-2209

  Kuo, Ching Chuan ^a,b   Wu, Tsang ^a   Chen, Li Tzong ^a,b,c   Shiah, Her Shyong ^a   Wu, Ching Ming ^b   Cheng, Yen Ting ^a   Pan, Wen Yu ^a   Liu, Jin Fen ^a   Chen, Kuo Li ^a   Yang, Yun Ning ^d   Chen, Shan Na ^a   Chang, Jang Yang ^a,c  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

^d NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

Author keywords

Arsenic trioxide; Autophagy; BCNU; Cancer therapy; Free radicals; Redox; Synergism

Indexed keywords

ARSENIC TRIOXIDE; CAMPTOTHECIN; CARMUSTINE; CISPLATIN; ETOPOSIDE; FLUOROURACIL; GLUTATHIONE; GLUTATHIONE REDUCTASE; PACLITAXEL; REACTIVE OXYGEN METABOLITE;

ARTICLE; AUTOPHAGY; CATALYSIS; CELL TYPE; CYTOTOXICITY; DRUG POTENTIATION; HUMAN; HUMAN CELL; IC 50; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; SOLID TUMOR;

ANTINEOPLASTIC AGENTS; ARSENICALS; AUTOPHAGY; CARMUSTINE; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; DRUG SCREENING ASSAYS, ANTITUMOR; GLUTATHIONE; GLUTATHIONE REDUCTASE; HUMANS; OXIDATION-REDUCTION; OXIDES; REACTIVE OXYGEN SPECIES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 81855176014     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.09.023     Document Type: Article

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