메뉴 건너뛰기




Volumn 21, Issue 21, 2002, Pages 5756-5765

Stress-induced decrease in TRAF2 stability is mediated by Siah2

Author keywords

JNK; NF ; Siah2; Stress; TRAF2

Indexed keywords

CYTOKINE; DACTINOMYCIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JANUS KINASE; MUTANT PROTEIN; PROTEIN SIAH2; REGULATOR PROTEIN; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; UNCLASSIFIED DRUG;

EID: 0036846371     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdf576     Document Type: Article
Times cited : (109)

References (45)
  • 1
    • 0031962348 scopus 로고    scopus 로고
    • 4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor KB
    • Arch, R.H. and Thompson, C.B. (1998) 4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor KB. Mol. Cell. Biol., 18, 558-565.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 558-565
    • Arch, R.H.1    Thompson, C.B.2
  • 2
    • 0032530455 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor associated factors (TRAFs) - A family of adapter proteins that regulates life and death
    • Arch, R.H., Gedrich, R.W. and Thompson, C.B. (1998) Tumor necrosis factor receptor associated factors (TRAFs) - A family of adapter proteins that regulates life and death. Genes Dev., 12, 2821-2830.
    • (1998) Genes Dev. , vol.12 , pp. 2821-2830
    • Arch, R.H.1    Gedrich, R.W.2    Thompson, C.B.3
  • 3
    • 0033563101 scopus 로고    scopus 로고
    • Signaling by proinflammatory cytokines: Oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain
    • Baud, V., Liu, Z.G., Bennett, B., Suzuki, N., Xia, Y. and Karin, M. (1999) Signaling by proinflammatory cytokines: Oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain Genes Dev., 13, 1297-1308.
    • (1999) Genes Dev. , vol.13 , pp. 1297-1308
    • Baud, V.1    Liu, Z.G.2    Bennett, B.3    Suzuki, N.4    Xia, Y.5    Karin, M.6
  • 4
    • 0035421173 scopus 로고    scopus 로고
    • Regulation of BOB.1/OBF.1 stability by SIAH
    • Boehm, J., He, Y., Greiner, A., Staudt, L. and Wirth, T. (2001) Regulation of BOB.1/OBF.1 stability by SIAH. EMBO J., 20, 4153-4162.
    • (2001) EMBO J. , vol.20 , pp. 4153-4162
    • Boehm, J.1    He, Y.2    Greiner, A.3    Staudt, L.4    Wirth, T.5
  • 5
    • 0035896734 scopus 로고    scopus 로고
    • Differential signaling and tumor necrosis factor receptor-associated factor (TRAF) degradation mediated by CD40 and the Epstein-Barr virus oncoprotein latent membrane protein 1 (LMP1)
    • Brown, K.D., Hostager, B.S. and Bishop, G.A. (2001) Differential signaling and tumor necrosis factor receptor-associated factor (TRAF) degradation mediated by CD40 and the Epstein-Barr virus oncoprotein latent membrane protein 1 (LMP1). J. Exp. Med., 193, 943-954.
    • (2001) J. Exp. Med. , vol.193 , pp. 943-954
    • Brown, K.D.1    Hostager, B.S.2    Bishop, G.A.3
  • 6
    • 0027262424 scopus 로고
    • Isolation and characterisation of murine homologues of the Drosophila seven in absentia gene (sina)
    • Della, N.G., Senior, P.V. and Bowtell, D.D.L. (1993) Isolation and characterisation of murine homologues of the Drosophila seven in absentia gene (sina). Development, 117, 1333-1343.
    • (1993) Development , vol.117 , pp. 1333-1343
    • Della, N.G.1    Senior, P.V.2    Bowtell, D.D.L.3
  • 7
    • 0033725155 scopus 로고    scopus 로고
    • The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation
    • Devin, A., Cook, A., Lin, Y., Rodriguez, Y., Kelliher, M. and Liu, Z.G. (2000) The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation. Immunity, 12, 419-429.
    • (2000) Immunity , vol.12 , pp. 419-429
    • Devin, A.1    Cook, A.2    Lin, Y.3    Rodriguez, Y.4    Kelliher, M.5    Liu, Z.G.6
  • 8
    • 0030828690 scopus 로고    scopus 로고
    • CD30-dependent degradation of TRAF2: Implications for negative regulation of TRAF signaling and the control of cell survival
    • Duckett, C.S. and Thompson, C.B. (1997) CD30-dependent degradation of TRAF2: Implications for negative regulation of TRAF signaling and the control of cell survival. Genes Dev., 11, 2810-2821.
    • (1997) Genes Dev. , vol.11 , pp. 2810-2821
    • Duckett, C.S.1    Thompson, C.B.2
  • 9
  • 10
    • 0035092687 scopus 로고    scopus 로고
    • The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27
    • Ganoth, D., Bornstein, G., Ko, T.K., Larsen, B., Tyers, M., Pagano, M. and Hershko, A. (2001) The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27. Nat. Cell Biol., 3, 321-324.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 321-324
    • Ganoth, D.1    Bornstein, G.2    Ko, T.K.3    Larsen, B.4    Tyers, M.5    Pagano, M.6    Hershko, A.7
  • 12
    • 0034619767 scopus 로고    scopus 로고
    • SIAH-1 interacts with α-tubulin and degrades the kinesin Kid by the proteasome pathway during mitosis
    • Germani, A., Bruzzoni-Giovanelli, H., Fellous, A., Gisselbrecht, S., Varin-Blank, N. and Calvo, F. (2000) SIAH-1 interacts with α-tubulin and degrades the kinesin Kid by the proteasome pathway during mitosis. Oncogene, 19, 5997-6006.
    • (2000) Oncogene , vol.19 , pp. 5997-6006
    • Germani, A.1    Bruzzoni-Giovanelli, H.2    Fellous, A.3    Gisselbrecht, S.4    Varin-Blank, N.5    Calvo, F.6
  • 13
    • 0030032106 scopus 로고    scopus 로고
    • TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
    • Hsu, H., Shu, H.B., Pan, M.G. and Goeddel, D.V. (1996) TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell, 84, 299-308.
    • (1996) Cell , vol.84 , pp. 299-308
    • Hsu, H.1    Shu, H.B.2    Pan, M.G.3    Goeddel, D.V.4
  • 14
    • 0032933351 scopus 로고    scopus 로고
    • Slab-1 N-terminal RING domain is required for proteolysis function and C-terminal sequences regulate oligomerization and binding to target proteins
    • Hu, G. and Fearon, E.R. (1999) Slab-1 N-terminal RING domain is required for proteolysis function and C-terminal sequences regulate oligomerization and binding to target proteins. Mol. Cell. Biol., 19, 724-732.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 724-732
    • Hu, G.1    Fearon, E.R.2
  • 15
    • 0030827862 scopus 로고    scopus 로고
    • Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway
    • Hu, G., Zhang, S., Vidal, M., Baer, J.L., Xu, T. and Fearon, E.R. (1997) Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway. Genes Dev., 11, 2701-2714.
    • (1997) Genes Dev. , vol.11 , pp. 2701-2714
    • Hu, G.1    Zhang, S.2    Vidal, M.3    Baer, J.L.4    Xu, T.5    Fearon, E.R.6
  • 16
    • 0035953398 scopus 로고    scopus 로고
    • Expression of ring finger-deleted TRAF2 sensitizes metastatic melanoma cells to apoptosis via up-regulation of p38, TNFα and suppression of NF-κB activities
    • Ivanov, V.N., Fodstad, O. and Ronai, Z. (2001) Expression of ring finger-deleted TRAF2 sensitizes metastatic melanoma cells to apoptosis via up-regulation of p38, TNFα and suppression of NF-κB activities. Oncogene, 20, 2243.
    • (2001) Oncogene , vol.20 , pp. 2243
    • Ivanov, V.N.1    Fodstad, O.2    Ronai, Z.3
  • 17
    • 0034266806 scopus 로고    scopus 로고
    • RING finger proteins: Mediators of ubiquitin ligase activity
    • Joazeiro, C.A.P. and Weissman, A.M. (2000) RING finger proteins: Mediators of ubiquitin ligase activity. Cell, 102, 549-552.
    • (2000) Cell , vol.102 , pp. 549-552
    • Joazeiro, C.A.P.1    Weissman, A.M.2
  • 18
    • 0025756330 scopus 로고
    • Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific
    • Lewis, M., Tartaglia, L.A., Lee, A., Bennett, G.L., Rice, G.C., Wong, G.H., Chen, E.Y. and Goeddel, D.V. (1991) Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific. Proc. Natl. Acad. Sci. USA, 88, 2830-2834.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 2830-2834
    • Lewis, M.1    Tartaglia, L.A.2    Lee, A.3    Bennett, G.L.4    Rice, G.C.5    Wong, G.H.6    Chen, E.Y.7    Goeddel, D.V.8
  • 19
    • 0037149542 scopus 로고    scopus 로고
    • TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2
    • Li, X., Yang, Y. and Ashwell, J.D. (2002) TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2. Nature, 416, 345-347.
    • (2002) Nature , vol.416 , pp. 345-347
    • Li, X.1    Yang, Y.2    Ashwell, J.D.3
  • 20
    • 0035947083 scopus 로고    scopus 로고
    • Siah-1 mediates a novel β-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein
    • Liu, J., Stevens, J., Rote, C.A., Yost, H.J., Hu, Y., Neufeld, K.L., White, R.L. and Matsunami, N. (2001) Siah-1 mediates a novel β-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein. Mol. Cell, 7, 927-936.
    • (2001) Mol. Cell , vol.7 , pp. 927-936
    • Liu, J.1    Stevens, J.2    Rote, C.A.3    Yost, H.J.4    Hu, Y.5    Neufeld, K.L.6    White, R.L.7    Matsunami, N.8
  • 21
    • 0030298294 scopus 로고    scopus 로고
    • Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death
    • Liu, Z.G., Hsu, H., Goeddel, D.V. and Karin, M. (1996) Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death Cell, 87, 565-576.
    • (1996) Cell , vol.87 , pp. 565-576
    • Liu, Z.G.1    Hsu, H.2    Goeddel, D.V.3    Karin, M.4
  • 22
    • 0033561039 scopus 로고    scopus 로고
    • TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40 and LPS signaling
    • Lomaga, M.A. et al. (1999) TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40 and LPS signaling. Genes Dev., 13, 1015-1024.
    • (1999) Genes Dev. , vol.13 , pp. 1015-1024
    • Lomaga, M.A.1
  • 23
    • 0035947080 scopus 로고    scopus 로고
    • Siah-1, SIP and Ebi collaborate in a novel pathway for β-catenin degradation linked to p53 responses
    • Matsuzawa, S. and Reed, J.C. (2001) Siah-1, SIP and Ebi collaborate in a novel pathway for β-catenin degradation linked to p53 responses. Mol. Cell, 7, 915-926.
    • (2001) Mol. Cell , vol.7 , pp. 915-926
    • Matsuzawa, S.1    Reed, J.C.2
  • 24
    • 0032525309 scopus 로고    scopus 로고
    • p53-inducible human homologue of Drosophila seven in absentia (Siah) inhibits cell growth: Suppression by BAG-1
    • Matsuzawa, S., Takayama, S., Froesch, B.A., Zapata, J.M. and Reed, J.C. (1998) p53-inducible human homologue of Drosophila seven in absentia (Siah) inhibits cell growth: Suppression by BAG-1. EMBO J., 17, 2736-2747.
    • (1998) EMBO J. , vol.17 , pp. 2736-2747
    • Matsuzawa, S.1    Takayama, S.2    Froesch, B.A.3    Zapata, J.M.4    Reed, J.C.5
  • 26
  • 28
    • 0033198702 scopus 로고    scopus 로고
    • TRAF2 deficiency results in hyperactivity of certain TNFR1 signals and impairment of CD40-mediated responses
    • Nguyen, L.T. et al. (1999) TRAF2 deficiency results in hyperactivity of certain TNFR1 signals and impairment of CD40-mediated responses. Immunity, 11, 379-389.
    • (1999) Immunity , vol.11 , pp. 379-389
    • Nguyen, L.T.1
  • 29
    • 0001033803 scopus 로고    scopus 로고
    • Structural basis for self-association and receptor recognition of human TRAF2
    • Park, Y.C., Burkitt, V., Villa, A.R., Tong, L. and Wu, H. (1999) Structural basis for self-association and receptor recognition of human TRAF2. Nature, 398, 533-538.
    • (1999) Nature , vol.398 , pp. 533-538
    • Park, Y.C.1    Burkitt, V.2    Villa, A.R.3    Tong, L.4    Wu, H.5
  • 31
    • 0031906851 scopus 로고    scopus 로고
    • Peg3/Pw1 is an imprinted gene involved in the TNF-NFκB signal transduction pathway
    • Relaix, F., Wei, X.J., Wu, X. and Sassoon, D.A. (1998) Peg3/Pw1 is an imprinted gene involved in the TNF-NFκB signal transduction pathway. Nat. Genet., 18, 287-291.
    • (1998) Nat. Genet. , vol.18 , pp. 287-291
    • Relaix, F.1    Wei, X.J.2    Wu, X.3    Sassoon, D.A.4
  • 32
  • 33
    • 0033529217 scopus 로고    scopus 로고
    • SIAH-1 promotes apoptosis and tumor suppression through a network involving the regulation of protein folding, unfolding and trafficking: Identification of common effectors with p53 and p21(Waf1)
    • Roperch, J.P. et al. (1999) SIAH-1 promotes apoptosis and tumor suppression through a network involving the regulation of protein folding, unfolding and trafficking: Identification of common effectors with p53 and p21(Waf1). Proc. Natl. Acad. Sci. USA. 96, 8070-8073.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 8070-8073
    • Roperch, J.P.1
  • 34
    • 0028978626 scopus 로고
    • TRAF2-mediated activation of NF-κB by TNF receptor 2 and CD40
    • Rothe, M., Sarma, V., Dixit, V.M. and Goeddel, D.V. (1995) TRAF2-mediated activation of NF-κB by TNF receptor 2 and CD40. Science, 269, 1424-1427.
    • (1995) Science , vol.269 , pp. 1424-1427
    • Rothe, M.1    Sarma, V.2    Dixit, V.M.3    Goeddel, D.V.4
  • 35
    • 0031437885 scopus 로고    scopus 로고
    • Activation of stress-activated protein kinase/c-Jun N-terminal kinase, but not NF-κB, by the tumor necrosis factor (TNF) receptor 1 through a TNF receptor-associated factor 2-and germinal center kinase related-dependent pathway
    • Shi, C.S. and Kehrl, J.H. (1997) Activation of stress-activated protein kinase/c-Jun N-terminal kinase, but not NF-κB, by the tumor necrosis factor (TNF) receptor 1 through a TNF receptor-associated factor 2-and germinal center kinase related-dependent pathway. J. Biol. Chem., 272, 32102-32107.
    • (1997) J. Biol. Chem. , vol.272 , pp. 32102-32107
    • Shi, C.S.1    Kehrl, J.H.2
  • 36
    • 0030447483 scopus 로고    scopus 로고
    • The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex
    • Shu, H.B., Takeuchi, M. and Goeddel, D.V. (1996) The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex. Proc. Natl. Acad. Sci. USA, 93, 13973-13978.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13973-13978
    • Shu, H.B.1    Takeuchi, M.2    Goeddel, D.V.3
  • 38
    • 0034735773 scopus 로고    scopus 로고
    • T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ
    • Takayanagi, H. et al. (2000) T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ. Nature, 408, 600-605.
    • (2000) Nature , vol.408 , pp. 600-605
    • Takayanagi, H.1
  • 39
    • 0030849728 scopus 로고    scopus 로고
    • PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism
    • Tang, A.H., Neufeld, T.P., Kwan, E. and Rubin, G.M. (1997) PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism. Cell, 90, 459-467.
    • (1997) Cell , vol.90 , pp. 459-467
    • Tang, A.H.1    Neufeld, T.P.2    Kwan, E.3    Rubin, G.M.4
  • 40
    • 0035421257 scopus 로고    scopus 로고
    • The RING finger protein Siah-1 regulates the level of the transcriptional coactivator OBF-1
    • Tiedt, R., Bartholdy, B.A., Matthias, G., Newell, J.W. and Matthias, P. (2001) The RING finger protein Siah-1 regulates the level of the transcriptional coactivator OBF-1. EMBO J., 20, 4143-4152.
    • (2001) EMBO J. , vol.20 , pp. 4143-4152
    • Tiedt, R.1    Bartholdy, B.A.2    Matthias, G.3    Newell, J.W.4    Matthias, P.5
  • 41
    • 0035122689 scopus 로고    scopus 로고
    • The TNF-receptor-associated factor family: Scaffold molecules for cytokine receptors, kinases and their regulators
    • Wajant, H. and Scheurich, P. (2001) The TNF-receptor-associated factor family: Scaffold molecules for cytokine receptors, kinases and their regulators. Int. J. Biochem. Cell Biol., 33, 19-32.
    • (2001) Int. J. Biochem. Cell Biol. , vol.33 , pp. 19-32
    • Wajant, H.1    Scheurich, P.2
  • 42
    • 0032508414 scopus 로고    scopus 로고
    • NF-κB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
    • Wang, C.Y., Mayo, M.W., Korneluk, R.G., Goeddel, D.V. and Baldwin, A.S., Jr (1998) NF-κB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science, 281, 1680-1683.
    • (1998) Science , vol.281 , pp. 1680-1683
    • Wang, C.Y.1    Mayo, M.W.2    Korneluk, R.G.3    Goeddel, D.V.4    Baldwin, A.S.5
  • 43
    • 0031463025 scopus 로고    scopus 로고
    • Early lethality, functional NF-κB activation and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice
    • Yeh, W.C. et al. (1997) Early lethality, functional NF-κB activation and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice. Immunity, 7, 715-725.
    • (1997) Immunity , vol.7 , pp. 715-725
    • Yeh, W.C.1
  • 44
    • 0034326624 scopus 로고    scopus 로고
    • TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies
    • Zapata, J.M. et al. (2000) TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies. J. Immunol., 165, 5084-5096.
    • (2000) J. Immunol. , vol.165 , pp. 5084-5096
    • Zapata, J.M.1
  • 45
    • 0032526024 scopus 로고    scopus 로고
    • Proteasomal regulation of nuclear receptor corepressor-mediated repression
    • Zhang, J., Guenther, M.G., Carthew, R.W. and Lazar, M.A. (1998) Proteasomal regulation of nuclear receptor corepressor-mediated repression. Genes Dev., 12, 1775-1780.
    • (1998) Genes Dev. , vol.12 , pp. 1775-1780
    • Zhang, J.1    Guenther, M.G.2    Carthew, R.W.3    Lazar, M.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.