EGCG inhibits transforming growth factor-β-mediated epithelial-to-mesenchymal transition via the inhibition of smad2 and Erk1/2 signaling pathways in nonsmall cell lung cancer cells

Journal of Agricultural and Food Chemistry

Volumn 60, Issue 39, 2012, Pages 9863-9873

  Liu, Liang Chih ^a,b,c,d   Tsao, Thomas Chang Yao ^e   Hsu, Shu Rong ^a   Wang, Hwei Chung ^b   Tsai, Tsuen Chiuan ^f   Kao, Jung Yie ^a   Way, Tzong Der ^a,g  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

^d FENG YUAN HOSPITAL   (Taiwan)

^e CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^f I SHOU UNIVERSITY   (Taiwan)

^g CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

EGCG; EMT; nonsmall cell lung cancer; Smad2; TGF

Indexed keywords

CANCER CELL GROWTH; DOWN-REGULATION; E-CADHERINS; EGCG; EMT; EPITHELIAL-MESENCHYMAL TRANSITION; HUMAN LUNG CANCER CELLS; IMMUNOFLUORESCENT STAINING; IN-VITRO; LUNG CANCER; MORPHOLOGICAL CHANGES; NON SMALL CELL LUNG CANCER; NUCLEAR TRANSLOCATIONS; PRE-TREATMENT; REPORTER ASSAY; SIGNALING PATHWAYS; SMAD2; TRANSCRIPTIONAL LEVELS; TRANSFORMING GROWTH FACTORS; TUMORIGENESIS; VIMENTIN; WOUND HEALING;

BIOLOGICAL ORGANS; CYTOLOGY; DISEASES; GLYCOPROTEINS; PHOSPHORYLATION; TRANSCRIPTION; TRANSCRIPTION FACTORS;

CELLS;

CATECHIN; DRUG DERIVATIVE; EPIGALLOCATECHIN GALLATE; PLANT EXTRACT; SMAD2 PROTEIN; SMAD2 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; DOWN REGULATION; DRUG EFFECT; EPITHELIAL MESENCHYMAL TRANSITION; GENETICS; HUMAN; LUNG NON SMALL CELL CANCER; LUNG TUMOR; METABOLISM; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

CARCINOMA, NON-SMALL-CELL LUNG; CATECHIN; CELL LINE, TUMOR; DOWN-REGULATION; EPITHELIAL-MESENCHYMAL TRANSITION; HUMANS; LUNG NEOPLASMS; MAP KINASE SIGNALING SYSTEM; PLANT EXTRACTS; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

GASTROPODA;

EID: 84867045697     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf303690x     Document Type: Article

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