(-)-epigallocatechin gallate induces Fas/CD95-mediated apoptosis through inhibiting constitutive and IL-6-induced JAK/STAT3 signaling in head and neck squamous cell carcinoma cells

Journal of Agricultural and Food Chemistry

Volumn 60, Issue 10, 2012, Pages 2480-2489

  Lin, Hui Yi ^a   Hou, Shin Chen ^b   Chen, Shi Chen ^a   Kao, Ming Ching ^b   Yu, Chien Chih ^a   Funayama, Shinji ^c   Ho, Chi Tang ^d   Way, Tzong Der ^b,e  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c NIHON PHARMACEUTICAL UNIVERSITY   (Japan)

^d RUTGERS UNIVERSITY   (United States)

^e NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

EGCG; Fas CD95; HNSCC; IL 6; STAT3

Indexed keywords

EGCG; FAS/CD95; HNSCC; IL-6; STAT3;

CELL DEATH; CYTOTOXICITY; GENE EXPRESSION REGULATION; PHOSPHORYLATION; TRANSCRIPTION;

IMMUNOLOGY;

CATECHIN; DRUG DERIVATIVE; EPIGALLOCATECHIN GALLATE; FAS LIGAND; INTERLEUKIN 6; STAT3 PROTEIN;

APOPTOSIS; ARTICLE; DOWN REGULATION; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HEAD AND NECK TUMOR; HUMAN; METABOLISM; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA;

APOPTOSIS; CARCINOMA, SQUAMOUS CELL; CATECHIN; DOWN-REGULATION; FAS LIGAND PROTEIN; GENE EXPRESSION REGULATION, NEOPLASTIC; HEAD AND NECK NEOPLASMS; HUMANS; INTERLEUKIN-6; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 84863351545     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf204362n     Document Type: Article

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