Transforming growth factor-β and epidermal growth factor synergistically stimulate epithelial to mesenchymal transition (EMT) through a MEK-dependent mechanism in primary cultured pig thyrocytes

Journal of Cell Science

Volumn 115, Issue 22, 2002, Pages 4227-4236

  Grände, Mats ^a   Franzen, Åsa ^b   Karlsson, Jan Olof ^a   Ericson, Lars E ^a   Heldin, Nils Erik ^b   Nilsson, Mikael ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Claudin; E cadherin; EGF; EMT; Erk; N cadherin; Occludin; TGF ; Thyroid

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; CLAUDIN 1; EPIDERMAL GROWTH FACTOR; GROWTH FACTOR; INULIN; MITOGEN ACTIVATED PROTEIN KINASE; NERVE CELL ADHESION MOLECULE; OCCLUDIN; TRANSFORMING GROWTH FACTOR BETA; TRITIUM; UVOMORULIN; CADHERIN; ENZYME INHIBITOR; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; PROTEIN SERINE THREONINE KINASE;

ANIMAL CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL INVASION; CELL JUNCTION; CELL STIMULATION; CELL STRUCTURE; CELL TRANSFORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EPITHELIUM CELL; FIBROBLAST; INHIBITION KINETICS; MESENCHYME CELL; MITOSIS INHIBITION; NONHUMAN; OBSERVATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVIEW; SWINE; THYROID CELL; TIGHT JUNCTION; TIME; TRANSPORT KINETICS; TUMOR GROWTH; ANIMAL; ARTICLE; CANCER INVASION; CELL SIZE; CYTOLOGY; DRUG EFFECT; DRUG INTERACTION; ELECTRON MICROSCOPY; ENZYMOLOGY; GENETICS; MESODERM; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; THYROID GLAND; ULTRASTRUCTURE;

ANIMALIA; SUS SCROFA; TRITIUM;

ADHERENS JUNCTIONS; ANIMALS; CADHERINS; CELL DIFFERENTIATION; CELL SIZE; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; DOWN-REGULATION; DRUG INTERACTIONS; ENZYME INHIBITORS; EPIDERMAL GROWTH FACTOR; EPITHELIAL CELLS; MAP KINASE KINASE 1; MEMBRANE PROTEINS; MESODERM; MICROSCOPY, ELECTRON; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASM INVASIVENESS; PROTEIN-SERINE-THREONINE KINASES; SUS SCROFA; THYROID GLAND; TIGHT JUNCTIONS; TRANSFORMING GROWTH FACTOR BETA;

EID: 18744362996     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.00091     Document Type: Review

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