Identification and analysis of hepatitis C virus NS3 helicase inhibitors using nucleic acid binding assays

Nucleic Acids Research

Volumn 40, Issue 17, 2012, Pages 8607-8621

  Mukherjee, Sourav ^a   Hanson, Alicia M ^a   Shadrick, William R ^a   Ndjomou, Jean ^a   Sweeney, Noreena L ^a   Hernandez, John J ^a   Bartczak, Diana ^a   Li, Kelin ^b   Frankowski, Kevin J ^b   Heck, Julie A ^c,d   Arnold, Leggy A ^b   Schoenen, Frank J ^b   Frick, David N ^a  

^a UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

^b UNIVERSITY OF KANSAS   (United States)

^c NEW YORK MEDICAL COLLEGE   (United States)

^d 931 College Mall   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AURINTRICARBOXYLIC ACID; DIRECT YELLOW 7; DNA; ENZYME INHIBITOR; HELICASE; HEPATITIS C VIRUS NONSTRUCTURAL PROTEIN 3 HELICASE INHIBITOR; NF 023; NONSTRUCTURAL PROTEIN 3; PRIMULIN; SINGLE STRANDED DNA BINDING PROTEIN; SURAMIN; TITAN YELLOW; TYRPHOSTIN AG 538; UNCLASSIFIED DRUG;

ALPHASCREEN ASSAY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DNA PROTEIN COMPLEX; DRUG IDENTIFICATION; ESCHERICHIA COLI; FLUORESCENCE POLARIZATION; FLUORESCENCE POLARIZATION BASED DNA BINDING ASSAY; GEL MOBILITY SHIFT ASSAY; HEPATITIS C VIRUS; HIGH THROUGHPUT SCREENING; HOMOGENEOUS TIME RESOLVED FLUORESCENCE POLARIZATION; IC 50; NONHUMAN; NUCLEIC ACID ANALYSIS; PRIORITY JOURNAL; REPLICON; VIRUS REPLICATION;

DNA; DNA-BINDING PROTEINS; ENZYME ASSAYS; ENZYME INHIBITORS; ESCHERICHIA COLI PROTEINS; FLUORESCENCE POLARIZATION; HEPACIVIRUS; HIGH-THROUGHPUT SCREENING ASSAYS; RNA HELICASES; SMALL MOLECULE LIBRARIES; VIRAL NONSTRUCTURAL PROTEINS;

ESCHERICHIA COLI; HEPATITIS C VIRUS;

EID: 84866952771     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gks623     Document Type: Article

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