Structure-based discovery of triphenylmethane derivatives as inhibitors of hepatitis C virus helicase

Journal of Medicinal Chemistry

Volumn 52, Issue 9, 2009, Pages 2716-2723

  Chen, Chien Shu ^a,b   Chiou, Chun Tang ^a,c   Chen, Grace Shiahuy ^d   Chen, Sheng Chia ^e   Hu, Chih Yung ^e   Chi, Wei Kuang ^f   Chu, Yi Ding ^f   Hwang, Lih Hwa ^a   Chen, Pei Jer ^a   Chen, Ding Shinn ^a   Liaw, Shwu Huey ^e   Chern, Ji Wang ^a,g  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^d PROVIDENCE UNIVERSITY   (Taiwan)

^e NATIONAL YANG MING UNIVERSITY   (Taiwan)

^f DEVELOPMENT CENTER FOR BIOTECHNOLOGY   (Taiwan)

^g NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

4 [1 (3 BROMO 4 HYDROXYPHENYL) 1 [4 [2 (3 BROMO 4 YDROXYPHENYL)PROPAN 2 YL]PHENYL]ETHYL] 2 BROMOPHENOL; ANTIVIRUS AGENT; HELICASE; HELICASE INHIBITOR; TRIPHENYLMETHANE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; ENZYME INHIBITOR INTERACTION; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; IC 50; STRUCTURE ACTIVITY RELATION;

EID: 84984532074     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm8011905     Document Type: Article

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