The serine protease domain of hepatitis C viral NS3 activates RNA helicase activity by promoting the binding of RNA substrate

Journal of Biological Chemistry

Volumn 282, Issue 48, 2007, Pages 34913-34920

  Beran, Rudolf K F ^a   Serebrov, Victor ^a   Pyle, Anna Marie ^a,b  

^a YALE UNIVERSITY   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUNCTIONAL MODULES; HELICASE FUNCTIONS; REPLICATIVE COMPLEX;

BINDING SITES; BIOACTIVITY; RNA;

ENZYME ACTIVITY;

MONTIRELIN; OLIGONUCLEOTIDE; RNA HELICASE; SERINE PROTEINASE; VIRUS RNA;

AMINO TERMINAL SEQUENCE; ARTICLE; ENZYMATIC ASSAY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME CONFORMATION; ENZYME SUBSTRATE COMPLEX; GENE SEQUENCE; HEPATITIS C VIRUS; LIFE CYCLE; MOLECULAR CLONING; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN PURIFICATION; PROTEIN RNA BINDING; PROTEIN STRUCTURE; RNA BINDING; VIRUS STRAIN; WESTERN BLOTTING;

ADENOSINE TRIPHOSPHATASES; ALLOSTERIC SITE; CLONING, MOLECULAR; ELECTROSTATICS; HEPACIVIRUS; KINETICS; MOLECULAR CONFORMATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RNA HELICASES; RNA, VIRAL; SUBSTRATE SPECIFICITY; VIRAL NONSTRUCTURAL PROTEINS;

HEPATITIS C VIRUS;

EID: 36849075152     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M707165200     Document Type: Article

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