-
1
-
-
48949098577
-
Gene therapy progress and prospects: Synthetic polymer-based systems
-
D. Schaffert, and E. Wagner Gene therapy progress and prospects: synthetic polymer-based systems Gene Ther. 15 2008 1131 1138
-
(2008)
Gene Ther.
, vol.15
, pp. 1131-1138
-
-
Schaffert, D.1
Wagner, E.2
-
2
-
-
79951579332
-
Flotillin-dependent endocytosis and a phagocytosis-like mechanism for cellular internalization of disulfide-based poly(amido amine)/DNA polyplexes
-
D. Vercauteren, M. Piest, L.J. van der Aa, M. Al Soraj, A.T. Jones, J.F.J. Engbersen, S.C. De Smedt, and K. Braeckmans Flotillin-dependent endocytosis and a phagocytosis-like mechanism for cellular internalization of disulfide-based poly(amido amine)/DNA polyplexes Biomaterials 32 2011 3072 3084
-
(2011)
Biomaterials
, vol.32
, pp. 3072-3084
-
-
Vercauteren, D.1
Piest, M.2
Van Der Aa, L.J.3
Al Soraj, M.4
Jones, A.T.5
Engbersen, J.F.J.6
De Smedt, S.C.7
Braeckmans, K.8
-
3
-
-
79952614101
-
In vivo nucleic acid delivery with PEI and its derivatives: Current status and perspectives
-
W.F. Lai In vivo nucleic acid delivery with PEI and its derivatives: current status and perspectives Expert Rev. Med. Devices 8 2011 173 185
-
(2011)
Expert Rev. Med. Devices
, vol.8
, pp. 173-185
-
-
Lai, W.F.1
-
4
-
-
33645224674
-
Targeting of Polyplexes: Toward Synthetic Virus Vector Systems
-
DOI 10.1016/S0065-2660(05)53013-X, PII S006526600553013X, Non-Viral Vectors for Gene Therapy, Second Edition: Part 1
-
E. Wagner, C. Culmsee, and S. Boeckle Targeting of polyplexes: toward synthetic virus vector systems Adv. Genet. 53PA 2005 333 354 (Pubitemid 43580674)
-
(2005)
Advances in Genetics
, vol.53
, pp. 333-354
-
-
Wagner, E.1
Culmsee, C.2
Boeckle, S.3
-
5
-
-
70049099303
-
Functional polymers for targeted delivery of nucleic acid drugs
-
H. Mok, and T.G. Park Functional polymers for targeted delivery of nucleic acid drugs Macromol. Biosci. 9 2009 731 743
-
(2009)
Macromol. Biosci.
, vol.9
, pp. 731-743
-
-
Mok, H.1
Park, T.G.2
-
6
-
-
80855148160
-
Combined MUC1-specific nanobody-tagged PEG-polyethylenimine polyplex targeting and transcriptional targeting of tBid transgene for directed killing of MUC1 over-expressing tumour cells
-
E. Sadeqzadeh, F. Rahbarizadeh, D. Ahmadvand, M.J. Rasaee, L. Parhamifar, and S.M. Moghimi Combined MUC1-specific nanobody-tagged PEG-polyethylenimine polyplex targeting and transcriptional targeting of tBid transgene for directed killing of MUC1 over-expressing tumour cells J. Control. Release 156 2011 85 91
-
(2011)
J. Control. Release
, vol.156
, pp. 85-91
-
-
Sadeqzadeh, E.1
Rahbarizadeh, F.2
Ahmadvand, D.3
Rasaee, M.J.4
Parhamifar, L.5
Moghimi, S.M.6
-
7
-
-
34547572345
-
Polymer systems for gene delivery-Past, present, and future
-
DOI 10.1016/j.progpolymsci.2007.05.007, PII S0079670007000718, Polymers in Biomedical Applications
-
S.Y. Wong, J.M. Pelet, and D. Putnam Polymer systems for gene delivery - past, present, and future Prog. Polym. Sci. 32 2007 799 837 (Pubitemid 47198291)
-
(2007)
Progress in Polymer Science (Oxford)
, vol.32
, Issue.8-9
, pp. 799-837
-
-
Wong, S.Y.1
Pelet, J.M.2
Putnam, D.3
-
8
-
-
63649115668
-
Targeting of the beta(2)-adrenoceptor increases nonviral gene delivery to pulmonary epithelial cells in vitro and lungs in vivo
-
M. Elfinger, J. Geiger, G. Hasenpusch, S. Uzgun, N. Sieverling, M.K. Aneja, C. Maucksch, and C. Rudolph Targeting of the beta(2)-adrenoceptor increases nonviral gene delivery to pulmonary epithelial cells in vitro and lungs in vivo J. Control. Release 135 2009 234 241
-
(2009)
J. Control. Release
, vol.135
, pp. 234-241
-
-
Elfinger, M.1
Geiger, J.2
Hasenpusch, G.3
Uzgun, S.4
Sieverling, N.5
Aneja, M.K.6
Maucksch, C.7
Rudolph, C.8
-
9
-
-
1642578411
-
Mechanism of improved gene transfer by the N-terminal stearylation of octaarginine: Enhanced cellular association by hydrophobic core formation
-
DOI 10.1038/sj.gt.3302128
-
I.A. Khalil, S. Futaki, M. Niwa, Y. Baba, N. Kaji, H. Kamiya, and H. Harashima Mechanism of improved gene transfer by the N-terminal stearylation of octaarginine: enhanced cellular association by hydrophobic core formation Gene Ther. 11 2004 636 644 (Pubitemid 38455982)
-
(2004)
Gene Therapy
, vol.11
, Issue.7
, pp. 636-644
-
-
Khalil, I.A.1
Futaki, S.2
Niwa, M.3
Baba, Y.4
Kaji, N.5
Kamiya, H.6
Harashima, H.7
-
10
-
-
33847309821
-
A comparison of the effectiveness of cationic polymers poly-l-lysine (PLL) and polyethylenimine (PEI) for non-viral delivery of plasmid DNA to bone marrow stromal cells (BMSC)
-
L.L. Farrell, J. Pepin, C. Kucharski, X. Lin, Z. Xu, and H. Uludag A comparison of the effectiveness of cationic polymers poly-l-lysine (PLL) and polyethylenimine (PEI) for non-viral delivery of plasmid DNA to bone marrow stromal cells (BMSC) Eur. J. Pharm. Biopharm. 65 2007 388 397
-
(2007)
Eur. J. Pharm. Biopharm.
, vol.65
, pp. 388-397
-
-
Farrell, L.L.1
Pepin, J.2
Kucharski, C.3
Lin, X.4
Xu, Z.5
Uludag, H.6
-
11
-
-
77956734528
-
Differential uptake of DNA-poly(ethylenimine) polyplexes in cells cultured on collagen and fibronectin surfaces
-
A. Dhaliwal, M. Maldonado, Z. Han, and T. Segura Differential uptake of DNA-poly(ethylenimine) polyplexes in cells cultured on collagen and fibronectin surfaces Acta Biomater. 6 2010 3436 3447
-
(2010)
Acta Biomater.
, vol.6
, pp. 3436-3447
-
-
Dhaliwal, A.1
Maldonado, M.2
Han, Z.3
Segura, T.4
-
12
-
-
77957343707
-
Chemical vectors for gene delivery: Uptake and intracellular trafficking
-
C. Pichon, L. Billiet, and P. Midoux Chemical vectors for gene delivery: uptake and intracellular trafficking Curr. Opin. Biotechnol. 21 2010 640 645
-
(2010)
Curr. Opin. Biotechnol.
, vol.21
, pp. 640-645
-
-
Pichon, C.1
Billiet, L.2
Midoux, P.3
-
13
-
-
33751226915
-
Evaluating the intracellular stability and unpacking of DNA nanocomplexes by quantum dots-FRET
-
DOI 10.1016/j.jconrel.2006.09.005, PII S0168365906004548
-
Y.P. Ho, H.H. Chen, K.W. Leong, and T.H. Wang Evaluating the intracellular stability and unpacking of DNA nanocomplexes by quantum dots-FRET J. Control. Release 116 2006 83 89 (Pubitemid 44792304)
-
(2006)
Journal of Controlled Release
, vol.116
, Issue.1
, pp. 83-89
-
-
Ho, Y.-P.1
Chen, H.H.2
Leong, K.W.3
Wang, T.-H.4
-
14
-
-
38649099106
-
Quantitative comparison of intracellular unpacking kinetics of polyplexes by a model constructed from quantum Dot-FRET
-
DOI 10.1038/sj.mt.6300392, PII 6300392
-
H.H. Chen, Y.P. Ho, X. Jiang, H.Q. Mao, T.H. Wang, and K.W. Leong Quantitative comparison of intracellular unpacking kinetics of polyplexes by a model constructed from quantum dot-FRET Mol. Ther. 16 2008 324 332 (Pubitemid 351168042)
-
(2008)
Molecular Therapy
, vol.16
, Issue.2
, pp. 324-332
-
-
Chen, H.H.1
Ho, Y.-P.2
Jiang, X.3
Mao, H.-Q.4
Wang, T.-H.5
Leong, K.W.6
-
15
-
-
77957569447
-
Intracellular trafficking and decondensation kinetics of chitosan-pDNA polyplexes
-
M. Thibault, S. Nimesh, M. Lavertu, and M.D. Buschmann Intracellular trafficking and decondensation kinetics of chitosan-pDNA polyplexes Mol. Ther. 18 2010 1787 1795
-
(2010)
Mol. Ther.
, vol.18
, pp. 1787-1795
-
-
Thibault, M.1
Nimesh, S.2
Lavertu, M.3
Buschmann, M.D.4
-
16
-
-
78650878303
-
Properties of PEI-based polyplex nanoparticles that correlate with their transfection efficacy
-
A.V. Ulasov, Y.V. Khramtsov, G.A. Trusov, A.A. Rosenkranz, E.D. Sverdlov, and A.S. Sobolev Properties of PEI-based polyplex nanoparticles that correlate with their transfection efficacy Mol. Ther. 19 2011 103 112
-
(2011)
Mol. Ther.
, vol.19
, pp. 103-112
-
-
Ulasov, A.V.1
Khramtsov, Y.V.2
Trusov, G.A.3
Rosenkranz, A.A.4
Sverdlov, E.D.5
Sobolev, A.S.6
-
17
-
-
79956206514
-
Investigation of transport and unpacking mechanisms of polyplexes for transfection efficacy on different cell lines
-
G.A. Trusov, A.V. Ulasov, E.A. Beletkaia, Y.V. Khramtsov, M.O. Durymanov, A.A. Rosenkranz, E.D. Sverdlov, and A.S. Sobolev Investigation of transport and unpacking mechanisms of polyplexes for transfection efficacy on different cell lines Dokl. Biochem. Biophys. 437 2011 77 79
-
(2011)
Dokl. Biochem. Biophys.
, vol.437
, pp. 77-79
-
-
Trusov, G.A.1
Ulasov, A.V.2
Beletkaia, E.A.3
Khramtsov, Y.V.4
Durymanov, M.O.5
Rosenkranz, A.A.6
Sverdlov, E.D.7
Sobolev, A.S.8
-
19
-
-
80051959840
-
Comprehensive field synopsis and systematic meta-analyses of genetic association studies in cutaneous melanoma
-
F. Chatzinasiou, C.M. Lill, K. Kypreou, I. Stefanaki, V. Nicolaou, G. Spyrou, E. Evangelou, J.T. Roehr, E. Kodela, A. Katsambas, H. Tsao, J.P. Ioannidis, L. Bertram, and A.J. Stratigos Comprehensive field synopsis and systematic meta-analyses of genetic association studies in cutaneous melanoma J. Natl. Cancer Inst. 103 2011 1227 1235
-
(2011)
J. Natl. Cancer Inst.
, vol.103
, pp. 1227-1235
-
-
Chatzinasiou, F.1
Lill, C.M.2
Kypreou, K.3
Stefanaki, I.4
Nicolaou, V.5
Spyrou, G.6
Evangelou, E.7
Roehr, J.T.8
Kodela, E.9
Katsambas, A.10
Tsao, H.11
Ioannidis, J.P.12
Bertram, L.13
Stratigos, A.J.14
-
20
-
-
0024407943
-
Characterization of receptors for α-melanocyte stimulating hormone on human melanoma cells
-
W. Siegrist, F. Solca, S. Stutz, L. Giuffre, S. Carrel, J. Girard, and A.N. Eberle Characterization of receptors for alpha-melanocyte-stimulating hormone on human melanoma cells Cancer Res. 49 1989 6352 6358 (Pubitemid 20000936)
-
(1989)
Cancer Research
, vol.49
, Issue.22
, pp. 6352-6358
-
-
Siegrist, W.1
Solca, F.2
Stutz, S.3
Giuffre, L.4
Carrel, S.5
Girard, J.6
Eberle, A.N.7
-
21
-
-
0030467197
-
Melanotropic peptide receptors: Membrane markers of human melanoma cells
-
DOI 10.1111/j.1600-0625.1996.tb00136.x
-
J. Jiang, S.D. Sharma, J.L. Fink, M.E. Hadley, and V.J. Hruby Melanotropic peptide receptors: membrane markers of human melanoma cells Exp. Dermatol. 5 1996 325 333 (Pubitemid 27060540)
-
(1996)
Experimental Dermatology
, vol.5
, Issue.6
, pp. 325-333
-
-
Jiang, J.1
Sharma, S.D.2
Fink, J.L.3
Hadley, M.E.4
Hruby, V.J.5
-
22
-
-
18544367370
-
Tissue distribution and differential expression of melanocortin 1 receptor, a malignant melanoma marker
-
DOI 10.1038/sj.bjc.6600441
-
F. Salazar-Onfray, M. López, A. Lundqvist, A. Aguirre, A. Escobar, A. Serrano, C. Korenblit, M. Petersson, V. Chhajlani, O. Larsson, and R. Kiessling Tissue distribution and differential expression of melanocortin 1 receptor, a malignant melanoma marker Br. J. Cancer 87 2002 414 422 (Pubitemid 34983565)
-
(2002)
British Journal of Cancer
, vol.87
, Issue.4
, pp. 414-422
-
-
Salazar-Onfray, F.1
Lopez, M.2
Lundqvist, A.3
Aguirre, A.4
Escobar, A.5
Serrano, A.6
Korenblit, C.7
Petersson, M.8
Chhajlani, V.9
Larsson, O.10
Kiessling, R.11
-
23
-
-
34047246838
-
Melanocortin 1 receptor is expressed by uveal malignant melanoma and can be considered a new target for diagnosis and immunotherapy
-
DOI 10.1167/iovs.06-0090
-
M.N. López, C. Pereda, M. Ramírez, A. Mendoza-Naranjo, A. Serrano, A. Ferreira, R. Poblete, A.M. Kalergis, R. Kiessling, and F. Salazar-Onfray Melanocortin 1 receptor is expressed by uveal malignant melanoma and can be considered a new target for diagnosis and immunotherapy Invest. Ophthalmol. Vis. Sci. 48 2007 1219 1227 (Pubitemid 351261417)
-
(2007)
Investigative Ophthalmology and Visual Science
, vol.48
, Issue.3
, pp. 1219-1227
-
-
Lopez, M.N.1
Pereda, C.2
Ramirez, M.3
Mendoza-Naranjo, A.4
Serrano, A.5
Ferreira, A.6
Poblete, R.7
Kalergis, A.M.8
Kiessling, R.9
Salazar-Onfray, F.10
-
24
-
-
0030063467
-
Immunological localisation of melanocortin 1 receptor on the cell surface of WM266-4 human melanoma cells
-
DOI 10.1016/0304-3835(95)04015-3
-
Y. Xia, R. Muceniece, and J.E. Wikberg Immunological localisation of melanocortin 1 receptor on the cell surface of WM266-4 human melanoma cells Cancer Lett. 98 1996 157 162 (Pubitemid 26013142)
-
(1996)
Cancer Letters
, vol.98
, Issue.2
, pp. 157-162
-
-
Xia, Y.1
Muceniece, R.2
Wikberg, J.E.S.3
-
25
-
-
0345476306
-
Detection of melanocortin-1 receptor antigenicity on human skin cells in culture and in situ
-
M. Bohm, D. Metze, U. Schulte, E. Becher, T.A. Luger, and T. Brzoska Detection of melanocortin-1 receptor antigenicity on human skin cells in culture and in situ Exp. Dermatol. 8 1999 453 461
-
(1999)
Exp. Dermatol.
, vol.8
, pp. 453-461
-
-
Bohm, M.1
Metze, D.2
Schulte, U.3
Becher, E.4
Luger, T.A.5
Brzoska, T.6
-
26
-
-
0028237203
-
The human melanocyte stimulating hormone receptor has evolved to become super-sensitive to melanocortin peptides
-
K.G. Mountjoy The human melanocyte stimulating hormone receptor has evolved to become super-sensitive to melanocortin peptides Mol. Cell. Endocrinol. 102 1994 7 11
-
(1994)
Mol. Cell. Endocrinol.
, vol.102
, pp. 7-11
-
-
Mountjoy, K.G.1
-
27
-
-
0034126009
-
1 receptor
-
DOI 10.1016/S0196-9781(99)00207-7, PII S0196978199002077
-
M. Szardenings, R. Muceniece, I. Mutule, F. Mutulis, and J.E. Wikberg New highly specific agonistic peptides for human melanocortin MC(1) receptor Peptides 21 2000 239 243 (Pubitemid 30182487)
-
(2000)
Peptides
, vol.21
, Issue.2
, pp. 239-243
-
-
Szardenings, M.1
Muceniece, R.2
Mutule, I.3
Mutulis, F.4
Wikberg, J.E.S.5
-
28
-
-
0021716406
-
A short amino acid sequence able to specify nuclear location
-
D. Kalderon, B.L. Roberts, W.D. Richardson, and A.E. Smith A short amino acid sequence able to specify nuclear location Cell 39 1984 499 509 (Pubitemid 15198589)
-
(1984)
Cell
, vol.39
, Issue.3
, pp. 499-509
-
-
Kalderon, D.1
Roberts, B.L.2
Richardson, W.D.3
Smith, A.E.4
-
29
-
-
0014121452
-
Analysis of polyethylenimine by spectrophotometry of its copper chelate
-
T.D. Perrine, and W.R. Landis Analysis of polyethylenimine by spectrophotometry of its copper chelate J. Polym. Sci. A1 5 1967 1993 2003
-
(1967)
J. Polym. Sci.
, vol.1 A
, Issue.5
, pp. 1993-2003
-
-
Perrine, T.D.1
Landis, W.R.2
-
30
-
-
0036293628
-
The structure of PEG-modified poly(ethylene imines) influences biodistribution and pharmacokinetics of their complexes with NF-κB decoy in mice
-
DOI 10.1023/A:1016152831963
-
K. Kunath, A. von Harpe, H. Petersen, D. Fischer, K. Voigt, T. Kissel, and U. Bickel The structure of PEG-modified poly(ethylene imines) influences biodistribution and pharmacokinetics of their complexes with NF-kappaB decoy in mice Pharm. Res. 19 2002 810 817 (Pubitemid 34686740)
-
(2002)
Pharmaceutical Research
, vol.19
, Issue.6
, pp. 810-817
-
-
Kunath, K.1
Von Harpe, A.2
Petersen, H.3
Fischer, D.4
Voigt, K.5
Kissel, T.6
Bickel, U.7
-
31
-
-
33845943770
-
Discarded free PEG-based assay for obtaining the modification extent of pegylated proteins
-
DOI 10.1016/j.talanta.2006.04.010, PII S0039914006002736
-
X.W. Gong, D.Z. Wei, M.L. He, and Y.C. Xiong Discarded free PEG-based assay for obtaining the modification extent of pegylated proteins Talanta 71 2007 381 384 (Pubitemid 46038414)
-
(2007)
Talanta
, vol.71
, Issue.1
, pp. 381-384
-
-
Gong, X.W.1
Wei, D.Z.2
He, M.L.3
Xiong, Y.C.4
-
32
-
-
0016801410
-
Spectrofluorometric determination of pharmaceuticals containing aromatic or aliphatic primary amino groups as their fluorescamine (fluram) derivatives
-
J.A. De Silva, and N. Strojny Spectrofluorometric determination of pharmaceuticals containing aromatic or aliphatic primary amino groups as their fluorescamine (fluram) derivatives Anal. Chem. 47 1975 714 718
-
(1975)
Anal. Chem.
, vol.47
, pp. 714-718
-
-
De Silva, J.A.1
Strojny, N.2
-
33
-
-
79959868818
-
DNA nuclear targeting sequences for non-viral gene delivery
-
E.V. van Gaal, R.S. Oosting, R. van Eijk, M. Bakowska, D. Feyen, R.J. Kok, W.E. Hennink, D.J. Crommelin, and E. Mastrobattista DNA nuclear targeting sequences for non-viral gene delivery Pharm. Res. 28 2011 1707 1722
-
(2011)
Pharm. Res.
, vol.28
, pp. 1707-1722
-
-
Van Gaal, E.V.1
Oosting, R.S.2
Van Eijk, R.3
Bakowska, M.4
Feyen, D.5
Kok, R.J.6
Hennink, W.E.7
Crommelin, D.J.8
Mastrobattista, E.9
-
34
-
-
79955524103
-
Efficient gene delivery of primary human cells using peptide linked polyethylenimine polymer hybrid
-
D. Dey, M. Inayathullah, A.S. Lee, M. Limiuex, X. Zhang, Y. Wu, D. Nag, P.E. De Almeida, L. Han, J. Rajadas, and J.C. Wu Efficient gene delivery of primary human cells using peptide linked polyethylenimine polymer hybrid Biomaterials 32 2011 4647 4658
-
(2011)
Biomaterials
, vol.32
, pp. 4647-4658
-
-
Dey, D.1
Inayathullah, M.2
Lee, A.S.3
Limiuex, M.4
Zhang, X.5
Wu, Y.6
Nag, D.7
De Almeida, P.E.8
Han, L.9
Rajadas, J.10
Wu, J.C.11
-
35
-
-
79959356569
-
Controlled release of plasmid DNA from hyaluronan nanoparticles
-
S. Mahor, E. Collin, B.C. Dash, and A. Pandit Controlled release of plasmid DNA from hyaluronan nanoparticles Curr. Drug Deliv. 8 2011 354 362
-
(2011)
Curr. Drug Deliv.
, vol.8
, pp. 354-362
-
-
Mahor, S.1
Collin, E.2
Dash, B.C.3
Pandit, A.4
-
37
-
-
0024354304
-
Determination of subcutaneous tumor size in athymic (nude) mice
-
DOI 10.1007/BF00300234
-
M.M. Tomayko, and C.P. Reynolds Determination of subcutaneous tumor size in athymic (nude) mice Cancer Chemother. Pharmacol. 24 1989 148 154 (Pubitemid 19163397)
-
(1989)
Cancer Chemotherapy and Pharmacology
, vol.24
, Issue.3
, pp. 148-154
-
-
Tomayko, M.M.1
Reynolds, C.P.2
-
38
-
-
0347137958
-
Melanocortin receptor-mediated mobilization of intracellular free calcium in HEK293 cells
-
K.G. Mountjoy, P.L. Kong, J.A. Taylor, D.H. Willard, and W.O. Wilkison Melanocortin receptor-mediated mobilization of intracellular free calcium in HEK293 cells Physiol. Genomics 5 2001 11 19 (Pubitemid 33675198)
-
(2001)
Physiological Genomics
, vol.2001
, Issue.5
, pp. 11-19
-
-
Mountjoy, K.G.1
Kong, P.L.2
Taylor, J.A.3
Willard, D.H.4
Wilkison, W.O.5
-
40
-
-
33749247082
-
The Internalization Route Resulting in Successful Gene Expression Depends on both Cell Line and Polyethylenimine Polyplex Type
-
DOI 10.1016/j.ymthe.2006.07.006, PII S1525001606002620
-
S.C. De Smedt, E. Wagner, and M. Ogris The internalization route resulting in successful gene expression depends on both cell line and polyethylenimine polyplex type Mol. Ther. 14 2006 745 753 (Pubitemid 44480760)
-
(2006)
Molecular Therapy
, vol.14
, Issue.5
, pp. 745-753
-
-
Von Gersdorff, K.1
Sanders, N.N.2
Vandenbroucke, R.3
De Smedt, S.C.4
Wagner, E.5
Ogris, M.6
-
41
-
-
33746214697
-
Entry of feline calicivirus is dependent on clathrin-mediated endocytosis and acidification in endosomes
-
DOI 10.1128/JVI.02452-05
-
A.D. Stuart, and T.D. Brown Entry of feline calicivirus is dependent on clathrin-mediated endocytosis and acidification in endosomes J. Virol. 80 2006 7500 7509 (Pubitemid 44092572)
-
(2006)
Journal of Virology
, vol.80
, Issue.15
, pp. 7500-7509
-
-
Stuart, A.D.1
Brown, T.D.K.2
-
42
-
-
79960098388
-
Unconventional internalization mechanisms underlying functional delivery of antisense oligonucleotides via cationic lipoplexes and polyplexes
-
X. Ming, K. Sato, and R.L. Juliano Unconventional internalization mechanisms underlying functional delivery of antisense oligonucleotides via cationic lipoplexes and polyplexes J. Control. Release 153 2011 83 92
-
(2011)
J. Control. Release
, vol.153
, pp. 83-92
-
-
Ming, X.1
Sato, K.2
Juliano, R.L.3
-
43
-
-
15244345318
-
Validation of pharmacodynamic assays to evaluate the clinical efficacy of an antisense compound (AEG 35156) targeted to the X-linked inhibitor of apoptosis protein XIAP
-
DOI 10.1038/sj.bjc.6602363
-
J. Cummings, T.H. Ward, E. La Casse, C. Lefebvre, M. St-Jean, J. Durkin, M. Ranson, and C. Dive Validation of pharmacodynamic assays to evaluate the clinical efficacy of an antisense compound (AEG 35156) targeted to the X-linked inhibitor of apoptosis protein XIAP Br. J. Cancer 14 2005 532 538 (Pubitemid 40395534)
-
(2005)
British Journal of Cancer
, vol.92
, Issue.3
, pp. 532-538
-
-
Cummings, J.1
Ward, T.H.2
LaCasse, E.3
Lefebvre, C.4
St-Jean, M.5
Durkin, J.6
Ranson, M.7
Dive, C.8
-
44
-
-
0037072576
-
Prospects for cationic polymers in gene and oligonucleotide therapy against cancer
-
DOI 10.1016/S0169-409X(02)00046-7, PII S0169409X02000467
-
T. Merdan, J. Kopecek, and T. Kissel Prospects for cationic polymers in gene and oligonucleotide therapy against cancer Adv. Drug Deliv. Rev. 54 2002 715 758 (Pubitemid 35247524)
-
(2002)
Advanced Drug Delivery Reviews
, vol.54
, Issue.5
, pp. 715-758
-
-
Merdan, T.1
Kopecek, J.2
Kissel, T.3
-
45
-
-
0032962975
-
Metabolic instability of plasmid DNA in the cytosol: A potential barrier to gene transfer
-
DOI 10.1038/sj.gt.3300867
-
D. Lechardeur, K.J. Sohn, M. Haardt, P.B. Joshi, M. Monck, R.W. Graham, B. Beatty, J. Squire, H. O'Brodovich, and G.L. Lukacs Metabolic instability of plasmid DNA in the cytosol: a potential barrier to gene transfer Gene Ther. 6 1999 482 497 (Pubitemid 29192657)
-
(1999)
Gene Therapy
, vol.6
, Issue.4
, pp. 482-497
-
-
Lechardeur, D.1
Sohn, K.-J.2
Haardt, M.3
Joshi, P.B.4
Monck, M.5
Graham, R.W.6
Beatty, B.7
Squire, J.8
O'Brodovich, H.9
Lukacs, G.L.10
-
46
-
-
1642443376
-
Quantitative three-dimensional analysis of the intracellular trafficking of plasmid DNA transfected by a nonviral gene delivery system using confocal laser scanning microscopy
-
DOI 10.1016/j.ymthe.2004.01.005
-
H. Akita, R. Ito, I.A. Khalil, S. Futaki, and H. Harashima Quantitative three-dimensional analysis of the intracellular trafficking of plasmid DNA transfected by a nonviral gene delivery system using confocal laser scanning microscopy Mol. Ther. 9 2004 443 451 (Pubitemid 38404534)
-
(2004)
Molecular Therapy
, vol.9
, Issue.3
, pp. 443-451
-
-
Akita, H.1
Ito, R.2
Khalil, I.A.3
Futaki, S.4
Harashima, H.5
-
47
-
-
33751048740
-
Cell signaling and trafficking of human melanocortin receptors in real time using two-photon fluorescence and confocal laser microscopy: Differentiation of agonists and antagonists
-
DOI 10.1111/j.1747-0285.2006.00432.x
-
M.Y. Cai, E.V. Varga, M. Stankova, A. Mayorov, J.W. Perry, H.I. Yamamura, D. Trivedi, and V.J. Hruby Cell signaling and trafficking of human melanocortin receptors in real time using two-photon fluorescence and confocal laser microscopy: differentiation of agonists and antagonists Chem. Biol. Drug Des. 68 2006 183 193 (Pubitemid 44760243)
-
(2006)
Chemical Biology and Drug Design
, vol.68
, Issue.4
, pp. 183-193
-
-
Cai, M.1
Varga, E.V.2
Stankova, M.3
Mayorov, A.4
Perry, J.W.5
Yamamura, H.I.6
Trivedi, D.7
Hruby, V.J.8
-
48
-
-
34047270236
-
Regulation of human melanocortin 1 receptor signaling and trafficking by Thr-308 and Ser-316 and its alteration in variant alleles associated with red hair and skin cancer
-
DOI 10.1074/jbc.M606865200
-
B.L. Sanchez-Laorden, C. Jimenez-Cervantes, and J.C. Garcia-Borron Regulation of human melanocortin 1 receptor signaling and trafficking by Thr-308 and Ser-316 and its alteration in variant alleles associated with red hair and skin cancer J. Biol. Chem. 282 2007 3241 3251 (Pubitemid 47084357)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.5
, pp. 3241-3251
-
-
Sanchez-Laorden, B.L.1
Jimenez-Cervantes, C.2
Garcia-Borron, J.C.3
-
49
-
-
78751704216
-
Polymer-related off-target effects in non-viral siRNA delivery
-
O.M. Merkel, A. Beyerle, B.M. Beckmann, M. Zheng, R.K. Hartmann, T. Stöger, and T.H. Kissel Polymer-related off-target effects in non-viral siRNA delivery Biomaterials 32 2011 2388 2398
-
(2011)
Biomaterials
, vol.32
, pp. 2388-2398
-
-
Merkel, O.M.1
Beyerle, A.2
Beckmann, B.M.3
Zheng, M.4
Hartmann, R.K.5
Stöger, T.6
Kissel, T.H.7
-
50
-
-
79952195039
-
The mechanism of selective transfection mediated by pentablock copolymers; Part I: Investigation of cellular uptake
-
B. Zhang, and S. Mallapragada The mechanism of selective transfection mediated by pentablock copolymers; part I: investigation of cellular uptake Acta Biomater. 7 2011 1570 1579
-
(2011)
Acta Biomater.
, vol.7
, pp. 1570-1579
-
-
Zhang, B.1
Mallapragada, S.2
-
51
-
-
33750976822
-
DNA polyplexes based on degradable oligoethylenimine-derivatives: Combination with EGF receptor targeting and endosomal release functions
-
DOI 10.1016/j.jconrel.2006.07.002, PII S0168365906003300
-
J. Kloeckner, S. Boeckle, D. Persson, W. Roedl, M. Ogris, K. Berg, and E. Wagner DNA polyplexes based on degradable oligoethylenimine-derivatives: combination with EGF receptor targeting and endosomal release functions J. Control. Release 116 2006 115 122 (Pubitemid 44854278)
-
(2006)
Journal of Controlled Release
, vol.116
, Issue.2 SPEC. ISSUE
, pp. 115-122
-
-
Kloeckner, J.1
Boeckle, S.2
Persson, D.3
Roedl, W.4
Ogris, M.5
Berg, K.6
Wagner, E.7
-
52
-
-
34447340202
-
Dual-ligand effect of transferrin and transforming growth factor alpha on polyethyleneimine-mediated gene delivery
-
DOI 10.1016/j.jconrel.2007.05.001, PII S0168365907002106
-
S. Kakimoto, T. Moriyama, T. Tanabe, S. Shinkai, and T. Nagasaki Dual-ligand effect of transferrin and transforming growth factor alpha on polyethyleneimine-mediated gene delivery J. Control. Release 120 2007 242 249 (Pubitemid 47058638)
-
(2007)
Journal of Controlled Release
, vol.120
, Issue.3
, pp. 242-249
-
-
Kakimoto, S.1
Moriyama, T.2
Tanabe, T.3
Shinkai, S.4
Nagasaki, T.5
-
53
-
-
0345357073
-
Transferrin-Containing, Cyclodextrin Polymer-Based Particles for Tumor-Targeted Gene Delivery
-
DOI 10.1021/bc034125f
-
N.C. Bellocq, S.H. Pun, G.S. Jensen, and M.E. Davis Transferrin- containing, cyclodextrin polymer-based particles for tumor-targeted gene delivery Bioconjug. Chem. 14 2003 1122 1132 (Pubitemid 37449039)
-
(2003)
Bioconjugate Chemistry
, vol.14
, Issue.6
, pp. 1122-1132
-
-
Bellocq, N.C.1
Pun, S.H.2
Jensen, G.S.3
Davis, M.E.4
-
54
-
-
39649095864
-
Degradable PEG-folate coated poly(DMAEA-co-BA)phosphazene-based polyplexes exhibit receptor-specific gene expression
-
J. Luten, M.J. van Steenbergen, M.C. Lok, A.M. de Graaff, C.F. van Nostrum, H. Talsma, and W.E. Hennink Degradable PEG-folate coated poly(DMAEA-co-BA)phosphazene-based polyplexes exhibit receptor-specific gene expression Eur. J. Pharm. Sci. 33 2008 241 251
-
(2008)
Eur. J. Pharm. Sci.
, vol.33
, pp. 241-251
-
-
Luten, J.1
Van Steenbergen, M.J.2
Lok, M.C.3
De Graaff, A.M.4
Van Nostrum, C.F.5
Talsma, H.6
Hennink, W.E.7
-
55
-
-
67649218953
-
Integrin alphaVbeta3 targeted gene delivery using RGD peptidomimetic conjugates with copolymers of PEGylated poly(ethylene imine)
-
O.M. Merkel, O. Germershaus, C.K. Wada, P.J. Tarcha, T. Merdan, and T. Kissel Integrin alphaVbeta3 targeted gene delivery using RGD peptidomimetic conjugates with copolymers of PEGylated poly(ethylene imine) Bioconjug. Chem. 20 2009 1270 1280
-
(2009)
Bioconjug. Chem.
, vol.20
, pp. 1270-1280
-
-
Merkel, O.M.1
Germershaus, O.2
Wada, C.K.3
Tarcha, P.J.4
Merdan, T.5
Kissel, T.6
-
56
-
-
34250768172
-
Cellular dynamics of EGF receptor-targeted synthetic viruses
-
DOI 10.1038/sj.mt.6300176, PII 6300176
-
K. de Bruin, N. Ruthardt, K. von Gersdorff, R. Bausinger, E. Wagner, M. Ogris, and C. Bräuchle Cellular dynamics of EGF receptor-targeted synthetic viruses Mol. Ther. 15 2007 1297 1305 (Pubitemid 46965326)
-
(2007)
Molecular Therapy
, vol.15
, Issue.7
, pp. 1297-1305
-
-
De Bruin, K.1
Ruthardt, N.2
Von Gersdorff, K.3
Bausinger, R.4
Wagner, E.5
Ogris, M.6
Brauchle, C.7
-
57
-
-
3042857264
-
A model for non-viral gene delivery: Through syndecan adhesion molecules and powered by actin
-
DOI 10.1002/jgm.558
-
I. Kopatz, J.S. Remy, and J.-P. Behr A model for non-viral gene delivery: through syndecan adhesion molecules and powered by actin J. Gene Med. 6 2004 769 776 (Pubitemid 40228093)
-
(2004)
Journal of Gene Medicine
, vol.6
, Issue.7
, pp. 769-776
-
-
Kopatz, I.1
Remy, J.-S.2
Behr, J.-P.3
-
58
-
-
77950504616
-
Syndecan signaling: When, where and why?
-
H.A. Multhaupt, A. Yoneda, J.R. Whiteford, E.S. Oh, W. Lee, and J.R. Couchman Syndecan signaling: when, where and why? J. Physiol. Pharmacol. 60 Suppl. 4 2009 31 38
-
(2009)
J. Physiol. Pharmacol.
, vol.60
, Issue.SUPPL. 4
, pp. 31-38
-
-
Multhaupt, H.A.1
Yoneda, A.2
Whiteford, J.R.3
Oh, E.S.4
Lee, W.5
Couchman, J.R.6
-
59
-
-
33746960721
-
A critical role for endocytosis in Wnt signaling
-
J.T. Blitzer, and R. Nusse A critical role for endocytosis in Wnt signaling BMC Cell Biol. 7 2006 28
-
(2006)
BMC Cell Biol.
, vol.7
, pp. 28
-
-
Blitzer, J.T.1
Nusse, R.2
-
60
-
-
43149107462
-
Opposing roles of syndecan-1 and syndecan-2 in polyethyleneimine-mediated gene delivery
-
S. Paris, A. Burlacu, and Y. Durocher Opposing roles of syndecan-1 and syndecan-2 in polyethyleneimine-mediated gene delivery J. Biol. Chem. 283 2008 7697 7704
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 7697-7704
-
-
Paris, S.1
Burlacu, A.2
Durocher, Y.3
-
61
-
-
0035823546
-
Extracellular glycosaminoglycans modify cellular trafficking of lipoplexes and polyplexes
-
M. Ruponen, S. Ronkko, P. Honkakoski, J. Pelkonen, M. Tammi, and A. Urtti Extracellular glycosaminoglycans modify cellular trafficking of lipoplexes and polyplexes J. Biol. Chem. 276 2001 33875 33880
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 33875-33880
-
-
Ruponen, M.1
Ronkko, S.2
Honkakoski, P.3
Pelkonen, J.4
Tammi, M.5
Urtti, A.6
-
62
-
-
41149086686
-
Extracellular barriers to in vivo PEI and PEGylated PEI polyplex-mediated gene delivery to the liver
-
DOI 10.1021/bc700388u
-
R.S. Burke, and S.H. Pun Extracellular barriers to in vivo PEI and PEGylated PEI polyplex-mediated gene delivery to the liver Bioconjug. Chem. 19 2008 693 704 (Pubitemid 351431402)
-
(2008)
Bioconjugate Chemistry
, vol.19
, Issue.3
, pp. 693-704
-
-
Burke, R.S.1
Pun, S.H.2
-
63
-
-
70350399516
-
Heparan sulfate proteoglycan modulation of Wnt5A signal transduction in metastatic melanoma cells
-
M.P. O'Connell, J.L. Fiori, E.K. Kershner, B.P. Frank, F.E. Indig, D.D. Taub, K.S. Hoek, and A.T. Weeraratna Heparan sulfate proteoglycan modulation of Wnt5A signal transduction in metastatic melanoma cells J. Biol. Chem. 284 2009 28704 28712
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 28704-28712
-
-
O'Connell, M.P.1
Fiori, J.L.2
Kershner, E.K.3
Frank, B.P.4
Indig, F.E.5
Taub, D.D.6
Hoek, K.S.7
Weeraratna, A.T.8
-
64
-
-
70350452116
-
Syndecan-2 regulates the migratory potential of melanoma cells
-
J.H. Lee, H. Park, H. Chung, S. Choi, Y. Kim, H. Yoo, T.Y. Kim, H.J. Hann, I. Seong, J. Kim, K.G. Kang, I.O. Han, and E.S. Oh Syndecan-2 regulates the migratory potential of melanoma cells J. Biol. Chem. 284 2009 27167 27175
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 27167-27175
-
-
Lee, J.H.1
Park, H.2
Chung, H.3
Choi, S.4
Kim, Y.5
Yoo, H.6
Kim, T.Y.7
Hann, H.J.8
Seong, I.9
Kim, J.10
Kang, K.G.11
Han, I.O.12
Oh, E.S.13
-
65
-
-
70350100352
-
Hear the Wnt Ror: How melanoma cells adjust to changes in Wnt
-
M.P. O'Connell, and A.T. Weeraratna Hear the Wnt Ror: how melanoma cells adjust to changes in Wnt Pigment Cell Melanoma Res. 22 2009 724 739
-
(2009)
Pigment Cell Melanoma Res.
, vol.22
, pp. 724-739
-
-
O'Connell, M.P.1
Weeraratna, A.T.2
-
66
-
-
11844290850
-
Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer
-
DOI 10.1002/jgm.598
-
S. Boeckle, K. von Gersdorff, S. van der Piepen, C. Culmsee, E. Wagner, and M. Ogris Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer J. Gene Med. 6 2004 1102 1111 (Pubitemid 40228122)
-
(2004)
Journal of Gene Medicine
, vol.6
, Issue.10
, pp. 1102-1111
-
-
Boeckle, S.1
Von Gersdorff, K.2
Van Der Piepen, S.3
Culmsee, C.4
Wagner, E.5
Ogris, M.6
-
67
-
-
79960860841
-
Mechanisms of polyethylenimine-mediated DNA delivery: Free carrier helps to overcome the barrier of cell-surface glycosaminoglycans
-
M. Hanzlikova, M. Ruponen, E. Galli, A. Raasmaja, V. Aseyev, H. Tenhu, A. Urtti, and M. Yliperttula Mechanisms of polyethylenimine-mediated DNA delivery: free carrier helps to overcome the barrier of cell-surface glycosaminoglycans J. Gene Med. 13 2011 402 409
-
(2011)
J. Gene Med.
, vol.13
, pp. 402-409
-
-
Hanzlikova, M.1
Ruponen, M.2
Galli, E.3
Raasmaja, A.4
Aseyev, V.5
Tenhu, H.6
Urtti, A.7
Yliperttula, M.8
-
68
-
-
0034694930
-
Receptor-mediated targeting of gene delivery vectors: Insights from molecular mechanisms for improved vehicle design
-
C.M. Varga, T.J. Wickham, and D.A. Lauffenburger Receptor-mediated targeting of gene delivery vectors: insights from molecular mechanisms for improved vehicle design Biotechnol. Bioeng. 70 2000 593 605
-
(2000)
Biotechnol. Bioeng.
, vol.70
, pp. 593-605
-
-
Varga, C.M.1
Wickham, T.J.2
Lauffenburger, D.A.3
-
69
-
-
0035189482
-
Quantitative analysis of synthetic gene delivery vector design properties
-
DOI 10.1006/mthe.2001.0475
-
C.M. Varga, K. Hong, and D.A. Lauffenburger Quantitative analysis of synthetic gene delivery vector design properties Mol. Ther. 4 2001 438 446 (Pubitemid 33100281)
-
(2001)
Molecular Therapy
, vol.4
, Issue.5
, pp. 438-446
-
-
Varga, C.M.1
Hong, K.2
Lauffenburger, D.A.3
-
70
-
-
0141851072
-
A model for the analysis of nonviral gene therapy
-
DOI 10.1038/sj.gt.3302076
-
G.A. Banks, R.J. Roselli, R. Chen, and T.D. Giorgio A model for the analysis of nonviral gene therapy Gene Ther. 10 2003 1766 1775 (Pubitemid 37121048)
-
(2003)
Gene Therapy
, vol.10
, Issue.20
, pp. 1766-1775
-
-
Banks, G.A.1
Roselli, R.J.2
Chen, R.3
Giorgio, T.D.4
-
71
-
-
21744462256
-
Quantitative comparison of polyethylenimine formulations and adenoviral vectors in terms of intracellular gene delivery processes
-
DOI 10.1038/sj.gt.3302495
-
C.M. Varga, N.C. Tedford, M. Thomas, A.M. Klibanov, L.G. Griffith, and D.A. Lauffenburger Quantitative comparison of polyethylenimine formulations and adenoviral vectors in terms of intracellular gene delivery processes Gene Ther. 12 2005 1023 1032 (Pubitemid 40946144)
-
(2005)
Gene Therapy
, vol.12
, Issue.13
, pp. 1023-1032
-
-
Varga, C.M.1
Tedford, N.C.2
Thomas, M.3
Klibanov, A.M.4
Griffith, L.G.5
Lauffenburger, D.A.6
-
72
-
-
33846796031
-
Understanding intracellular transport processes pertinent to synthetic gene delivery via stochastic simulations and sensitivity analyses
-
DOI 10.1529/biophysj.106.095521
-
A.T. Dinh, C. Pangarkar, T. Theofanous, and S. Mitragotri Understanding intracellular transport processes pertinent to synthetic gene delivery via stochastic simulations and sensitivity analyses Biophys. J. 92 2007 831 846 (Pubitemid 46203213)
-
(2007)
Biophysical Journal
, vol.92
, Issue.3
, pp. 831-846
-
-
Dinh, A.-T.1
Pangarkar, C.2
Theofanous, T.3
Mitragotri, S.4
-
73
-
-
0032561334
-
Optimization of cell surface binding enhances efficiency and specificity of molecular conjugate gene delivery
-
DOI 10.1074/jbc.273.43.28004
-
D.V. Schaffer, and D.A. Lauffenburger Optimization of cell surface binding enhances efficiency and specificity of molecular conjugate gene delivery J. Biol. Chem. 273 1998 28004 28009 (Pubitemid 28496092)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.43
, pp. 28004-28009
-
-
Schaffer, D.V.1
Lauffenburger, D.A.2
|