메뉴 건너뛰기




Volumn 163, Issue 2, 2012, Pages 211-219

Subcellular trafficking and transfection efficacy of polyethylenimine- polyethylene glycol polyplex nanoparticles with a ligand to melanocortin receptor-1

Author keywords

Intracellular trafficking; Melanocortin receptor 1; Polyethylene glycol; Polyethylenimine; Polyplexes; Transfection

Indexed keywords

INTRACELLULAR TRAFFICKING; MELANOCORTIN RECEPTOR-1; POLYETHYLENIMINES; POLYPLEXES; TRANSFECTION;

EID: 84866690470     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.08.027     Document Type: Article
Times cited : (37)

References (73)
  • 1
    • 48949098577 scopus 로고    scopus 로고
    • Gene therapy progress and prospects: Synthetic polymer-based systems
    • D. Schaffert, and E. Wagner Gene therapy progress and prospects: synthetic polymer-based systems Gene Ther. 15 2008 1131 1138
    • (2008) Gene Ther. , vol.15 , pp. 1131-1138
    • Schaffert, D.1    Wagner, E.2
  • 2
    • 79951579332 scopus 로고    scopus 로고
    • Flotillin-dependent endocytosis and a phagocytosis-like mechanism for cellular internalization of disulfide-based poly(amido amine)/DNA polyplexes
    • D. Vercauteren, M. Piest, L.J. van der Aa, M. Al Soraj, A.T. Jones, J.F.J. Engbersen, S.C. De Smedt, and K. Braeckmans Flotillin-dependent endocytosis and a phagocytosis-like mechanism for cellular internalization of disulfide-based poly(amido amine)/DNA polyplexes Biomaterials 32 2011 3072 3084
    • (2011) Biomaterials , vol.32 , pp. 3072-3084
    • Vercauteren, D.1    Piest, M.2    Van Der Aa, L.J.3    Al Soraj, M.4    Jones, A.T.5    Engbersen, J.F.J.6    De Smedt, S.C.7    Braeckmans, K.8
  • 3
    • 79952614101 scopus 로고    scopus 로고
    • In vivo nucleic acid delivery with PEI and its derivatives: Current status and perspectives
    • W.F. Lai In vivo nucleic acid delivery with PEI and its derivatives: current status and perspectives Expert Rev. Med. Devices 8 2011 173 185
    • (2011) Expert Rev. Med. Devices , vol.8 , pp. 173-185
    • Lai, W.F.1
  • 4
    • 33645224674 scopus 로고    scopus 로고
    • Targeting of Polyplexes: Toward Synthetic Virus Vector Systems
    • DOI 10.1016/S0065-2660(05)53013-X, PII S006526600553013X, Non-Viral Vectors for Gene Therapy, Second Edition: Part 1
    • E. Wagner, C. Culmsee, and S. Boeckle Targeting of polyplexes: toward synthetic virus vector systems Adv. Genet. 53PA 2005 333 354 (Pubitemid 43580674)
    • (2005) Advances in Genetics , vol.53 , pp. 333-354
    • Wagner, E.1    Culmsee, C.2    Boeckle, S.3
  • 5
    • 70049099303 scopus 로고    scopus 로고
    • Functional polymers for targeted delivery of nucleic acid drugs
    • H. Mok, and T.G. Park Functional polymers for targeted delivery of nucleic acid drugs Macromol. Biosci. 9 2009 731 743
    • (2009) Macromol. Biosci. , vol.9 , pp. 731-743
    • Mok, H.1    Park, T.G.2
  • 6
    • 80855148160 scopus 로고    scopus 로고
    • Combined MUC1-specific nanobody-tagged PEG-polyethylenimine polyplex targeting and transcriptional targeting of tBid transgene for directed killing of MUC1 over-expressing tumour cells
    • E. Sadeqzadeh, F. Rahbarizadeh, D. Ahmadvand, M.J. Rasaee, L. Parhamifar, and S.M. Moghimi Combined MUC1-specific nanobody-tagged PEG-polyethylenimine polyplex targeting and transcriptional targeting of tBid transgene for directed killing of MUC1 over-expressing tumour cells J. Control. Release 156 2011 85 91
    • (2011) J. Control. Release , vol.156 , pp. 85-91
    • Sadeqzadeh, E.1    Rahbarizadeh, F.2    Ahmadvand, D.3    Rasaee, M.J.4    Parhamifar, L.5    Moghimi, S.M.6
  • 7
    • 34547572345 scopus 로고    scopus 로고
    • Polymer systems for gene delivery-Past, present, and future
    • DOI 10.1016/j.progpolymsci.2007.05.007, PII S0079670007000718, Polymers in Biomedical Applications
    • S.Y. Wong, J.M. Pelet, and D. Putnam Polymer systems for gene delivery - past, present, and future Prog. Polym. Sci. 32 2007 799 837 (Pubitemid 47198291)
    • (2007) Progress in Polymer Science (Oxford) , vol.32 , Issue.8-9 , pp. 799-837
    • Wong, S.Y.1    Pelet, J.M.2    Putnam, D.3
  • 8
    • 63649115668 scopus 로고    scopus 로고
    • Targeting of the beta(2)-adrenoceptor increases nonviral gene delivery to pulmonary epithelial cells in vitro and lungs in vivo
    • M. Elfinger, J. Geiger, G. Hasenpusch, S. Uzgun, N. Sieverling, M.K. Aneja, C. Maucksch, and C. Rudolph Targeting of the beta(2)-adrenoceptor increases nonviral gene delivery to pulmonary epithelial cells in vitro and lungs in vivo J. Control. Release 135 2009 234 241
    • (2009) J. Control. Release , vol.135 , pp. 234-241
    • Elfinger, M.1    Geiger, J.2    Hasenpusch, G.3    Uzgun, S.4    Sieverling, N.5    Aneja, M.K.6    Maucksch, C.7    Rudolph, C.8
  • 9
    • 1642578411 scopus 로고    scopus 로고
    • Mechanism of improved gene transfer by the N-terminal stearylation of octaarginine: Enhanced cellular association by hydrophobic core formation
    • DOI 10.1038/sj.gt.3302128
    • I.A. Khalil, S. Futaki, M. Niwa, Y. Baba, N. Kaji, H. Kamiya, and H. Harashima Mechanism of improved gene transfer by the N-terminal stearylation of octaarginine: enhanced cellular association by hydrophobic core formation Gene Ther. 11 2004 636 644 (Pubitemid 38455982)
    • (2004) Gene Therapy , vol.11 , Issue.7 , pp. 636-644
    • Khalil, I.A.1    Futaki, S.2    Niwa, M.3    Baba, Y.4    Kaji, N.5    Kamiya, H.6    Harashima, H.7
  • 10
    • 33847309821 scopus 로고    scopus 로고
    • A comparison of the effectiveness of cationic polymers poly-l-lysine (PLL) and polyethylenimine (PEI) for non-viral delivery of plasmid DNA to bone marrow stromal cells (BMSC)
    • L.L. Farrell, J. Pepin, C. Kucharski, X. Lin, Z. Xu, and H. Uludag A comparison of the effectiveness of cationic polymers poly-l-lysine (PLL) and polyethylenimine (PEI) for non-viral delivery of plasmid DNA to bone marrow stromal cells (BMSC) Eur. J. Pharm. Biopharm. 65 2007 388 397
    • (2007) Eur. J. Pharm. Biopharm. , vol.65 , pp. 388-397
    • Farrell, L.L.1    Pepin, J.2    Kucharski, C.3    Lin, X.4    Xu, Z.5    Uludag, H.6
  • 11
    • 77956734528 scopus 로고    scopus 로고
    • Differential uptake of DNA-poly(ethylenimine) polyplexes in cells cultured on collagen and fibronectin surfaces
    • A. Dhaliwal, M. Maldonado, Z. Han, and T. Segura Differential uptake of DNA-poly(ethylenimine) polyplexes in cells cultured on collagen and fibronectin surfaces Acta Biomater. 6 2010 3436 3447
    • (2010) Acta Biomater. , vol.6 , pp. 3436-3447
    • Dhaliwal, A.1    Maldonado, M.2    Han, Z.3    Segura, T.4
  • 12
    • 77957343707 scopus 로고    scopus 로고
    • Chemical vectors for gene delivery: Uptake and intracellular trafficking
    • C. Pichon, L. Billiet, and P. Midoux Chemical vectors for gene delivery: uptake and intracellular trafficking Curr. Opin. Biotechnol. 21 2010 640 645
    • (2010) Curr. Opin. Biotechnol. , vol.21 , pp. 640-645
    • Pichon, C.1    Billiet, L.2    Midoux, P.3
  • 13
    • 33751226915 scopus 로고    scopus 로고
    • Evaluating the intracellular stability and unpacking of DNA nanocomplexes by quantum dots-FRET
    • DOI 10.1016/j.jconrel.2006.09.005, PII S0168365906004548
    • Y.P. Ho, H.H. Chen, K.W. Leong, and T.H. Wang Evaluating the intracellular stability and unpacking of DNA nanocomplexes by quantum dots-FRET J. Control. Release 116 2006 83 89 (Pubitemid 44792304)
    • (2006) Journal of Controlled Release , vol.116 , Issue.1 , pp. 83-89
    • Ho, Y.-P.1    Chen, H.H.2    Leong, K.W.3    Wang, T.-H.4
  • 14
    • 38649099106 scopus 로고    scopus 로고
    • Quantitative comparison of intracellular unpacking kinetics of polyplexes by a model constructed from quantum Dot-FRET
    • DOI 10.1038/sj.mt.6300392, PII 6300392
    • H.H. Chen, Y.P. Ho, X. Jiang, H.Q. Mao, T.H. Wang, and K.W. Leong Quantitative comparison of intracellular unpacking kinetics of polyplexes by a model constructed from quantum dot-FRET Mol. Ther. 16 2008 324 332 (Pubitemid 351168042)
    • (2008) Molecular Therapy , vol.16 , Issue.2 , pp. 324-332
    • Chen, H.H.1    Ho, Y.-P.2    Jiang, X.3    Mao, H.-Q.4    Wang, T.-H.5    Leong, K.W.6
  • 15
    • 77957569447 scopus 로고    scopus 로고
    • Intracellular trafficking and decondensation kinetics of chitosan-pDNA polyplexes
    • M. Thibault, S. Nimesh, M. Lavertu, and M.D. Buschmann Intracellular trafficking and decondensation kinetics of chitosan-pDNA polyplexes Mol. Ther. 18 2010 1787 1795
    • (2010) Mol. Ther. , vol.18 , pp. 1787-1795
    • Thibault, M.1    Nimesh, S.2    Lavertu, M.3    Buschmann, M.D.4
  • 18
    • 28044450150 scopus 로고    scopus 로고
    • Melanocortin-1 receptor structure and functional regulation
    • DOI 10.1111/j.1600-0749.2005.00278.x
    • J.C. García-Borrón, B.L. Sánchez-Laorden, and C. Jiménez-Cervantes Melanocortin-1 receptor structure and functional regulation Pigment Cell Res. 18 2005 393 410 (Pubitemid 41691455)
    • (2005) Pigment Cell Research , vol.18 , Issue.6 , pp. 393-410
    • Garcia-Borron, J.C.1    Sanchez-Laorden, B.L.2    Jimenez-Cervantes, C.3
  • 20
    • 0024407943 scopus 로고
    • Characterization of receptors for α-melanocyte stimulating hormone on human melanoma cells
    • W. Siegrist, F. Solca, S. Stutz, L. Giuffre, S. Carrel, J. Girard, and A.N. Eberle Characterization of receptors for alpha-melanocyte-stimulating hormone on human melanoma cells Cancer Res. 49 1989 6352 6358 (Pubitemid 20000936)
    • (1989) Cancer Research , vol.49 , Issue.22 , pp. 6352-6358
    • Siegrist, W.1    Solca, F.2    Stutz, S.3    Giuffre, L.4    Carrel, S.5    Girard, J.6    Eberle, A.N.7
  • 21
    • 0030467197 scopus 로고    scopus 로고
    • Melanotropic peptide receptors: Membrane markers of human melanoma cells
    • DOI 10.1111/j.1600-0625.1996.tb00136.x
    • J. Jiang, S.D. Sharma, J.L. Fink, M.E. Hadley, and V.J. Hruby Melanotropic peptide receptors: membrane markers of human melanoma cells Exp. Dermatol. 5 1996 325 333 (Pubitemid 27060540)
    • (1996) Experimental Dermatology , vol.5 , Issue.6 , pp. 325-333
    • Jiang, J.1    Sharma, S.D.2    Fink, J.L.3    Hadley, M.E.4    Hruby, V.J.5
  • 24
    • 0030063467 scopus 로고    scopus 로고
    • Immunological localisation of melanocortin 1 receptor on the cell surface of WM266-4 human melanoma cells
    • DOI 10.1016/0304-3835(95)04015-3
    • Y. Xia, R. Muceniece, and J.E. Wikberg Immunological localisation of melanocortin 1 receptor on the cell surface of WM266-4 human melanoma cells Cancer Lett. 98 1996 157 162 (Pubitemid 26013142)
    • (1996) Cancer Letters , vol.98 , Issue.2 , pp. 157-162
    • Xia, Y.1    Muceniece, R.2    Wikberg, J.E.S.3
  • 25
    • 0345476306 scopus 로고    scopus 로고
    • Detection of melanocortin-1 receptor antigenicity on human skin cells in culture and in situ
    • M. Bohm, D. Metze, U. Schulte, E. Becher, T.A. Luger, and T. Brzoska Detection of melanocortin-1 receptor antigenicity on human skin cells in culture and in situ Exp. Dermatol. 8 1999 453 461
    • (1999) Exp. Dermatol. , vol.8 , pp. 453-461
    • Bohm, M.1    Metze, D.2    Schulte, U.3    Becher, E.4    Luger, T.A.5    Brzoska, T.6
  • 26
    • 0028237203 scopus 로고
    • The human melanocyte stimulating hormone receptor has evolved to become super-sensitive to melanocortin peptides
    • K.G. Mountjoy The human melanocyte stimulating hormone receptor has evolved to become super-sensitive to melanocortin peptides Mol. Cell. Endocrinol. 102 1994 7 11
    • (1994) Mol. Cell. Endocrinol. , vol.102 , pp. 7-11
    • Mountjoy, K.G.1
  • 27
    • 0034126009 scopus 로고    scopus 로고
    • 1 receptor
    • DOI 10.1016/S0196-9781(99)00207-7, PII S0196978199002077
    • M. Szardenings, R. Muceniece, I. Mutule, F. Mutulis, and J.E. Wikberg New highly specific agonistic peptides for human melanocortin MC(1) receptor Peptides 21 2000 239 243 (Pubitemid 30182487)
    • (2000) Peptides , vol.21 , Issue.2 , pp. 239-243
    • Szardenings, M.1    Muceniece, R.2    Mutule, I.3    Mutulis, F.4    Wikberg, J.E.S.5
  • 28
    • 0021716406 scopus 로고
    • A short amino acid sequence able to specify nuclear location
    • D. Kalderon, B.L. Roberts, W.D. Richardson, and A.E. Smith A short amino acid sequence able to specify nuclear location Cell 39 1984 499 509 (Pubitemid 15198589)
    • (1984) Cell , vol.39 , Issue.3 , pp. 499-509
    • Kalderon, D.1    Roberts, B.L.2    Richardson, W.D.3    Smith, A.E.4
  • 29
    • 0014121452 scopus 로고
    • Analysis of polyethylenimine by spectrophotometry of its copper chelate
    • T.D. Perrine, and W.R. Landis Analysis of polyethylenimine by spectrophotometry of its copper chelate J. Polym. Sci. A1 5 1967 1993 2003
    • (1967) J. Polym. Sci. , vol.1 A , Issue.5 , pp. 1993-2003
    • Perrine, T.D.1    Landis, W.R.2
  • 30
    • 0036293628 scopus 로고    scopus 로고
    • The structure of PEG-modified poly(ethylene imines) influences biodistribution and pharmacokinetics of their complexes with NF-κB decoy in mice
    • DOI 10.1023/A:1016152831963
    • K. Kunath, A. von Harpe, H. Petersen, D. Fischer, K. Voigt, T. Kissel, and U. Bickel The structure of PEG-modified poly(ethylene imines) influences biodistribution and pharmacokinetics of their complexes with NF-kappaB decoy in mice Pharm. Res. 19 2002 810 817 (Pubitemid 34686740)
    • (2002) Pharmaceutical Research , vol.19 , Issue.6 , pp. 810-817
    • Kunath, K.1    Von Harpe, A.2    Petersen, H.3    Fischer, D.4    Voigt, K.5    Kissel, T.6    Bickel, U.7
  • 31
    • 33845943770 scopus 로고    scopus 로고
    • Discarded free PEG-based assay for obtaining the modification extent of pegylated proteins
    • DOI 10.1016/j.talanta.2006.04.010, PII S0039914006002736
    • X.W. Gong, D.Z. Wei, M.L. He, and Y.C. Xiong Discarded free PEG-based assay for obtaining the modification extent of pegylated proteins Talanta 71 2007 381 384 (Pubitemid 46038414)
    • (2007) Talanta , vol.71 , Issue.1 , pp. 381-384
    • Gong, X.W.1    Wei, D.Z.2    He, M.L.3    Xiong, Y.C.4
  • 32
    • 0016801410 scopus 로고
    • Spectrofluorometric determination of pharmaceuticals containing aromatic or aliphatic primary amino groups as their fluorescamine (fluram) derivatives
    • J.A. De Silva, and N. Strojny Spectrofluorometric determination of pharmaceuticals containing aromatic or aliphatic primary amino groups as their fluorescamine (fluram) derivatives Anal. Chem. 47 1975 714 718
    • (1975) Anal. Chem. , vol.47 , pp. 714-718
    • De Silva, J.A.1    Strojny, N.2
  • 35
    • 79959356569 scopus 로고    scopus 로고
    • Controlled release of plasmid DNA from hyaluronan nanoparticles
    • S. Mahor, E. Collin, B.C. Dash, and A. Pandit Controlled release of plasmid DNA from hyaluronan nanoparticles Curr. Drug Deliv. 8 2011 354 362
    • (2011) Curr. Drug Deliv. , vol.8 , pp. 354-362
    • Mahor, S.1    Collin, E.2    Dash, B.C.3    Pandit, A.4
  • 37
    • 0024354304 scopus 로고
    • Determination of subcutaneous tumor size in athymic (nude) mice
    • DOI 10.1007/BF00300234
    • M.M. Tomayko, and C.P. Reynolds Determination of subcutaneous tumor size in athymic (nude) mice Cancer Chemother. Pharmacol. 24 1989 148 154 (Pubitemid 19163397)
    • (1989) Cancer Chemotherapy and Pharmacology , vol.24 , Issue.3 , pp. 148-154
    • Tomayko, M.M.1    Reynolds, C.P.2
  • 38
    • 0347137958 scopus 로고    scopus 로고
    • Melanocortin receptor-mediated mobilization of intracellular free calcium in HEK293 cells
    • K.G. Mountjoy, P.L. Kong, J.A. Taylor, D.H. Willard, and W.O. Wilkison Melanocortin receptor-mediated mobilization of intracellular free calcium in HEK293 cells Physiol. Genomics 5 2001 11 19 (Pubitemid 33675198)
    • (2001) Physiological Genomics , vol.2001 , Issue.5 , pp. 11-19
    • Mountjoy, K.G.1    Kong, P.L.2    Taylor, J.A.3    Willard, D.H.4    Wilkison, W.O.5
  • 40
    • 33749247082 scopus 로고    scopus 로고
    • The Internalization Route Resulting in Successful Gene Expression Depends on both Cell Line and Polyethylenimine Polyplex Type
    • DOI 10.1016/j.ymthe.2006.07.006, PII S1525001606002620
    • S.C. De Smedt, E. Wagner, and M. Ogris The internalization route resulting in successful gene expression depends on both cell line and polyethylenimine polyplex type Mol. Ther. 14 2006 745 753 (Pubitemid 44480760)
    • (2006) Molecular Therapy , vol.14 , Issue.5 , pp. 745-753
    • Von Gersdorff, K.1    Sanders, N.N.2    Vandenbroucke, R.3    De Smedt, S.C.4    Wagner, E.5    Ogris, M.6
  • 41
    • 33746214697 scopus 로고    scopus 로고
    • Entry of feline calicivirus is dependent on clathrin-mediated endocytosis and acidification in endosomes
    • DOI 10.1128/JVI.02452-05
    • A.D. Stuart, and T.D. Brown Entry of feline calicivirus is dependent on clathrin-mediated endocytosis and acidification in endosomes J. Virol. 80 2006 7500 7509 (Pubitemid 44092572)
    • (2006) Journal of Virology , vol.80 , Issue.15 , pp. 7500-7509
    • Stuart, A.D.1    Brown, T.D.K.2
  • 42
    • 79960098388 scopus 로고    scopus 로고
    • Unconventional internalization mechanisms underlying functional delivery of antisense oligonucleotides via cationic lipoplexes and polyplexes
    • X. Ming, K. Sato, and R.L. Juliano Unconventional internalization mechanisms underlying functional delivery of antisense oligonucleotides via cationic lipoplexes and polyplexes J. Control. Release 153 2011 83 92
    • (2011) J. Control. Release , vol.153 , pp. 83-92
    • Ming, X.1    Sato, K.2    Juliano, R.L.3
  • 43
    • 15244345318 scopus 로고    scopus 로고
    • Validation of pharmacodynamic assays to evaluate the clinical efficacy of an antisense compound (AEG 35156) targeted to the X-linked inhibitor of apoptosis protein XIAP
    • DOI 10.1038/sj.bjc.6602363
    • J. Cummings, T.H. Ward, E. La Casse, C. Lefebvre, M. St-Jean, J. Durkin, M. Ranson, and C. Dive Validation of pharmacodynamic assays to evaluate the clinical efficacy of an antisense compound (AEG 35156) targeted to the X-linked inhibitor of apoptosis protein XIAP Br. J. Cancer 14 2005 532 538 (Pubitemid 40395534)
    • (2005) British Journal of Cancer , vol.92 , Issue.3 , pp. 532-538
    • Cummings, J.1    Ward, T.H.2    LaCasse, E.3    Lefebvre, C.4    St-Jean, M.5    Durkin, J.6    Ranson, M.7    Dive, C.8
  • 44
    • 0037072576 scopus 로고    scopus 로고
    • Prospects for cationic polymers in gene and oligonucleotide therapy against cancer
    • DOI 10.1016/S0169-409X(02)00046-7, PII S0169409X02000467
    • T. Merdan, J. Kopecek, and T. Kissel Prospects for cationic polymers in gene and oligonucleotide therapy against cancer Adv. Drug Deliv. Rev. 54 2002 715 758 (Pubitemid 35247524)
    • (2002) Advanced Drug Delivery Reviews , vol.54 , Issue.5 , pp. 715-758
    • Merdan, T.1    Kopecek, J.2    Kissel, T.3
  • 46
    • 1642443376 scopus 로고    scopus 로고
    • Quantitative three-dimensional analysis of the intracellular trafficking of plasmid DNA transfected by a nonviral gene delivery system using confocal laser scanning microscopy
    • DOI 10.1016/j.ymthe.2004.01.005
    • H. Akita, R. Ito, I.A. Khalil, S. Futaki, and H. Harashima Quantitative three-dimensional analysis of the intracellular trafficking of plasmid DNA transfected by a nonviral gene delivery system using confocal laser scanning microscopy Mol. Ther. 9 2004 443 451 (Pubitemid 38404534)
    • (2004) Molecular Therapy , vol.9 , Issue.3 , pp. 443-451
    • Akita, H.1    Ito, R.2    Khalil, I.A.3    Futaki, S.4    Harashima, H.5
  • 47
    • 33751048740 scopus 로고    scopus 로고
    • Cell signaling and trafficking of human melanocortin receptors in real time using two-photon fluorescence and confocal laser microscopy: Differentiation of agonists and antagonists
    • DOI 10.1111/j.1747-0285.2006.00432.x
    • M.Y. Cai, E.V. Varga, M. Stankova, A. Mayorov, J.W. Perry, H.I. Yamamura, D. Trivedi, and V.J. Hruby Cell signaling and trafficking of human melanocortin receptors in real time using two-photon fluorescence and confocal laser microscopy: differentiation of agonists and antagonists Chem. Biol. Drug Des. 68 2006 183 193 (Pubitemid 44760243)
    • (2006) Chemical Biology and Drug Design , vol.68 , Issue.4 , pp. 183-193
    • Cai, M.1    Varga, E.V.2    Stankova, M.3    Mayorov, A.4    Perry, J.W.5    Yamamura, H.I.6    Trivedi, D.7    Hruby, V.J.8
  • 48
    • 34047270236 scopus 로고    scopus 로고
    • Regulation of human melanocortin 1 receptor signaling and trafficking by Thr-308 and Ser-316 and its alteration in variant alleles associated with red hair and skin cancer
    • DOI 10.1074/jbc.M606865200
    • B.L. Sanchez-Laorden, C. Jimenez-Cervantes, and J.C. Garcia-Borron Regulation of human melanocortin 1 receptor signaling and trafficking by Thr-308 and Ser-316 and its alteration in variant alleles associated with red hair and skin cancer J. Biol. Chem. 282 2007 3241 3251 (Pubitemid 47084357)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.5 , pp. 3241-3251
    • Sanchez-Laorden, B.L.1    Jimenez-Cervantes, C.2    Garcia-Borron, J.C.3
  • 50
    • 79952195039 scopus 로고    scopus 로고
    • The mechanism of selective transfection mediated by pentablock copolymers; Part I: Investigation of cellular uptake
    • B. Zhang, and S. Mallapragada The mechanism of selective transfection mediated by pentablock copolymers; part I: investigation of cellular uptake Acta Biomater. 7 2011 1570 1579
    • (2011) Acta Biomater. , vol.7 , pp. 1570-1579
    • Zhang, B.1    Mallapragada, S.2
  • 51
    • 33750976822 scopus 로고    scopus 로고
    • DNA polyplexes based on degradable oligoethylenimine-derivatives: Combination with EGF receptor targeting and endosomal release functions
    • DOI 10.1016/j.jconrel.2006.07.002, PII S0168365906003300
    • J. Kloeckner, S. Boeckle, D. Persson, W. Roedl, M. Ogris, K. Berg, and E. Wagner DNA polyplexes based on degradable oligoethylenimine-derivatives: combination with EGF receptor targeting and endosomal release functions J. Control. Release 116 2006 115 122 (Pubitemid 44854278)
    • (2006) Journal of Controlled Release , vol.116 , Issue.2 SPEC. ISSUE , pp. 115-122
    • Kloeckner, J.1    Boeckle, S.2    Persson, D.3    Roedl, W.4    Ogris, M.5    Berg, K.6    Wagner, E.7
  • 52
    • 34447340202 scopus 로고    scopus 로고
    • Dual-ligand effect of transferrin and transforming growth factor alpha on polyethyleneimine-mediated gene delivery
    • DOI 10.1016/j.jconrel.2007.05.001, PII S0168365907002106
    • S. Kakimoto, T. Moriyama, T. Tanabe, S. Shinkai, and T. Nagasaki Dual-ligand effect of transferrin and transforming growth factor alpha on polyethyleneimine-mediated gene delivery J. Control. Release 120 2007 242 249 (Pubitemid 47058638)
    • (2007) Journal of Controlled Release , vol.120 , Issue.3 , pp. 242-249
    • Kakimoto, S.1    Moriyama, T.2    Tanabe, T.3    Shinkai, S.4    Nagasaki, T.5
  • 53
    • 0345357073 scopus 로고    scopus 로고
    • Transferrin-Containing, Cyclodextrin Polymer-Based Particles for Tumor-Targeted Gene Delivery
    • DOI 10.1021/bc034125f
    • N.C. Bellocq, S.H. Pun, G.S. Jensen, and M.E. Davis Transferrin- containing, cyclodextrin polymer-based particles for tumor-targeted gene delivery Bioconjug. Chem. 14 2003 1122 1132 (Pubitemid 37449039)
    • (2003) Bioconjugate Chemistry , vol.14 , Issue.6 , pp. 1122-1132
    • Bellocq, N.C.1    Pun, S.H.2    Jensen, G.S.3    Davis, M.E.4
  • 55
    • 67649218953 scopus 로고    scopus 로고
    • Integrin alphaVbeta3 targeted gene delivery using RGD peptidomimetic conjugates with copolymers of PEGylated poly(ethylene imine)
    • O.M. Merkel, O. Germershaus, C.K. Wada, P.J. Tarcha, T. Merdan, and T. Kissel Integrin alphaVbeta3 targeted gene delivery using RGD peptidomimetic conjugates with copolymers of PEGylated poly(ethylene imine) Bioconjug. Chem. 20 2009 1270 1280
    • (2009) Bioconjug. Chem. , vol.20 , pp. 1270-1280
    • Merkel, O.M.1    Germershaus, O.2    Wada, C.K.3    Tarcha, P.J.4    Merdan, T.5    Kissel, T.6
  • 57
    • 3042857264 scopus 로고    scopus 로고
    • A model for non-viral gene delivery: Through syndecan adhesion molecules and powered by actin
    • DOI 10.1002/jgm.558
    • I. Kopatz, J.S. Remy, and J.-P. Behr A model for non-viral gene delivery: through syndecan adhesion molecules and powered by actin J. Gene Med. 6 2004 769 776 (Pubitemid 40228093)
    • (2004) Journal of Gene Medicine , vol.6 , Issue.7 , pp. 769-776
    • Kopatz, I.1    Remy, J.-S.2    Behr, J.-P.3
  • 59
    • 33746960721 scopus 로고    scopus 로고
    • A critical role for endocytosis in Wnt signaling
    • J.T. Blitzer, and R. Nusse A critical role for endocytosis in Wnt signaling BMC Cell Biol. 7 2006 28
    • (2006) BMC Cell Biol. , vol.7 , pp. 28
    • Blitzer, J.T.1    Nusse, R.2
  • 60
    • 43149107462 scopus 로고    scopus 로고
    • Opposing roles of syndecan-1 and syndecan-2 in polyethyleneimine-mediated gene delivery
    • S. Paris, A. Burlacu, and Y. Durocher Opposing roles of syndecan-1 and syndecan-2 in polyethyleneimine-mediated gene delivery J. Biol. Chem. 283 2008 7697 7704
    • (2008) J. Biol. Chem. , vol.283 , pp. 7697-7704
    • Paris, S.1    Burlacu, A.2    Durocher, Y.3
  • 61
    • 0035823546 scopus 로고    scopus 로고
    • Extracellular glycosaminoglycans modify cellular trafficking of lipoplexes and polyplexes
    • M. Ruponen, S. Ronkko, P. Honkakoski, J. Pelkonen, M. Tammi, and A. Urtti Extracellular glycosaminoglycans modify cellular trafficking of lipoplexes and polyplexes J. Biol. Chem. 276 2001 33875 33880
    • (2001) J. Biol. Chem. , vol.276 , pp. 33875-33880
    • Ruponen, M.1    Ronkko, S.2    Honkakoski, P.3    Pelkonen, J.4    Tammi, M.5    Urtti, A.6
  • 62
    • 41149086686 scopus 로고    scopus 로고
    • Extracellular barriers to in vivo PEI and PEGylated PEI polyplex-mediated gene delivery to the liver
    • DOI 10.1021/bc700388u
    • R.S. Burke, and S.H. Pun Extracellular barriers to in vivo PEI and PEGylated PEI polyplex-mediated gene delivery to the liver Bioconjug. Chem. 19 2008 693 704 (Pubitemid 351431402)
    • (2008) Bioconjugate Chemistry , vol.19 , Issue.3 , pp. 693-704
    • Burke, R.S.1    Pun, S.H.2
  • 65
    • 70350100352 scopus 로고    scopus 로고
    • Hear the Wnt Ror: How melanoma cells adjust to changes in Wnt
    • M.P. O'Connell, and A.T. Weeraratna Hear the Wnt Ror: how melanoma cells adjust to changes in Wnt Pigment Cell Melanoma Res. 22 2009 724 739
    • (2009) Pigment Cell Melanoma Res. , vol.22 , pp. 724-739
    • O'Connell, M.P.1    Weeraratna, A.T.2
  • 66
    • 11844290850 scopus 로고    scopus 로고
    • Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer
    • DOI 10.1002/jgm.598
    • S. Boeckle, K. von Gersdorff, S. van der Piepen, C. Culmsee, E. Wagner, and M. Ogris Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer J. Gene Med. 6 2004 1102 1111 (Pubitemid 40228122)
    • (2004) Journal of Gene Medicine , vol.6 , Issue.10 , pp. 1102-1111
    • Boeckle, S.1    Von Gersdorff, K.2    Van Der Piepen, S.3    Culmsee, C.4    Wagner, E.5    Ogris, M.6
  • 67
    • 79960860841 scopus 로고    scopus 로고
    • Mechanisms of polyethylenimine-mediated DNA delivery: Free carrier helps to overcome the barrier of cell-surface glycosaminoglycans
    • M. Hanzlikova, M. Ruponen, E. Galli, A. Raasmaja, V. Aseyev, H. Tenhu, A. Urtti, and M. Yliperttula Mechanisms of polyethylenimine-mediated DNA delivery: free carrier helps to overcome the barrier of cell-surface glycosaminoglycans J. Gene Med. 13 2011 402 409
    • (2011) J. Gene Med. , vol.13 , pp. 402-409
    • Hanzlikova, M.1    Ruponen, M.2    Galli, E.3    Raasmaja, A.4    Aseyev, V.5    Tenhu, H.6    Urtti, A.7    Yliperttula, M.8
  • 68
    • 0034694930 scopus 로고    scopus 로고
    • Receptor-mediated targeting of gene delivery vectors: Insights from molecular mechanisms for improved vehicle design
    • C.M. Varga, T.J. Wickham, and D.A. Lauffenburger Receptor-mediated targeting of gene delivery vectors: insights from molecular mechanisms for improved vehicle design Biotechnol. Bioeng. 70 2000 593 605
    • (2000) Biotechnol. Bioeng. , vol.70 , pp. 593-605
    • Varga, C.M.1    Wickham, T.J.2    Lauffenburger, D.A.3
  • 69
    • 0035189482 scopus 로고    scopus 로고
    • Quantitative analysis of synthetic gene delivery vector design properties
    • DOI 10.1006/mthe.2001.0475
    • C.M. Varga, K. Hong, and D.A. Lauffenburger Quantitative analysis of synthetic gene delivery vector design properties Mol. Ther. 4 2001 438 446 (Pubitemid 33100281)
    • (2001) Molecular Therapy , vol.4 , Issue.5 , pp. 438-446
    • Varga, C.M.1    Hong, K.2    Lauffenburger, D.A.3
  • 70
    • 0141851072 scopus 로고    scopus 로고
    • A model for the analysis of nonviral gene therapy
    • DOI 10.1038/sj.gt.3302076
    • G.A. Banks, R.J. Roselli, R. Chen, and T.D. Giorgio A model for the analysis of nonviral gene therapy Gene Ther. 10 2003 1766 1775 (Pubitemid 37121048)
    • (2003) Gene Therapy , vol.10 , Issue.20 , pp. 1766-1775
    • Banks, G.A.1    Roselli, R.J.2    Chen, R.3    Giorgio, T.D.4
  • 71
    • 21744462256 scopus 로고    scopus 로고
    • Quantitative comparison of polyethylenimine formulations and adenoviral vectors in terms of intracellular gene delivery processes
    • DOI 10.1038/sj.gt.3302495
    • C.M. Varga, N.C. Tedford, M. Thomas, A.M. Klibanov, L.G. Griffith, and D.A. Lauffenburger Quantitative comparison of polyethylenimine formulations and adenoviral vectors in terms of intracellular gene delivery processes Gene Ther. 12 2005 1023 1032 (Pubitemid 40946144)
    • (2005) Gene Therapy , vol.12 , Issue.13 , pp. 1023-1032
    • Varga, C.M.1    Tedford, N.C.2    Thomas, M.3    Klibanov, A.M.4    Griffith, L.G.5    Lauffenburger, D.A.6
  • 72
    • 33846796031 scopus 로고    scopus 로고
    • Understanding intracellular transport processes pertinent to synthetic gene delivery via stochastic simulations and sensitivity analyses
    • DOI 10.1529/biophysj.106.095521
    • A.T. Dinh, C. Pangarkar, T. Theofanous, and S. Mitragotri Understanding intracellular transport processes pertinent to synthetic gene delivery via stochastic simulations and sensitivity analyses Biophys. J. 92 2007 831 846 (Pubitemid 46203213)
    • (2007) Biophysical Journal , vol.92 , Issue.3 , pp. 831-846
    • Dinh, A.-T.1    Pangarkar, C.2    Theofanous, T.3    Mitragotri, S.4
  • 73
    • 0032561334 scopus 로고    scopus 로고
    • Optimization of cell surface binding enhances efficiency and specificity of molecular conjugate gene delivery
    • DOI 10.1074/jbc.273.43.28004
    • D.V. Schaffer, and D.A. Lauffenburger Optimization of cell surface binding enhances efficiency and specificity of molecular conjugate gene delivery J. Biol. Chem. 273 1998 28004 28009 (Pubitemid 28496092)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.43 , pp. 28004-28009
    • Schaffer, D.V.1    Lauffenburger, D.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.