Regulation of human melanocortin 1 receptor signaling and trafficking by Thr-308 and Ser-316 and its alteration in variant alleles associated with red hair and skin cancer

Journal of Biological Chemistry

Volumn 282, Issue 5, 2007, Pages 3241-3251

  Sánchez Laorden, Berta L ^a   Jiménez Cervantes, Celia ^a   García Borrón, José C ^a  

^a UNIVERSITY OF MURCIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN MELANOCORTIN 1 RECEPTOR; PHOTOPROTECTIVE EUMELANINS; SKIN CANCER RISK;

CELLS; MUTAGENESIS; ONCOLOGY; PHOSPHORYLATION; PIGMENTS; PROTEINS; SKIN;

NEUROLOGY;

G PROTEIN COUPLED RECEPTOR KINASE; G PROTEIN COUPLED RECEPTOR KINASE 2; MELANOCORTIN 1 RECEPTOR; SERINE; THREONINE; CYCLIC AMP; RECOMBINANT PROTEIN;

ALLELE; ANIMAL CELL; ARTICLE; CANCER RISK; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYTOSOL; DESENSITIZATION; EMBRYO; ENDOSOME; ENZYME SPECIFICITY; GENETIC ASSOCIATION; GENETIC VARIABILITY; HAIR COLOR; HUMAN; HUMAN CELL; INTERNALIZATION; MELANOCYTE; MELANOGENESIS; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SKIN CANCER; AMINO ACID SEQUENCE; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; PROTEIN CONFORMATION; SKIN TUMOR;

AMINO ACID SEQUENCE; CELL LINE; CYCLIC AMP; HAIR COLOR; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; RECEPTOR, MELANOCORTIN, TYPE 1; RECOMBINANT PROTEINS; SERINE; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; THREONINE; TRANSFECTION; VARIATION (GENETICS);

EID: 34047270236     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M606865200     Document Type: Article

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