Genetic Inhibition of CaMKII in Dorsal Striatal Medium Spiny Neurons Reduces Functional Excitatory Synapses and Enhances Intrinsic Excitability

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Klug, Jason R ^a   Mathur, Brian N ^c   Kash, Thomas L ^a,e   Wang, Hui Dong ^b   Matthews, Robert T ^a,b   Robison, A J ^a,f   Anderson, Mark E ^d   Deutch, Ariel Y ^a,b   Lovinger, David M ^c   Colbran, Roger J ^a,b   Winder, Danny G ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^d UNIVERSITY OF IOWA   (United States)

^e UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^f MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPA RECEPTOR; AMPA RECEPTOR GLUA1; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CELL PROTEIN; GLUTAMIC ACID; LYSYLLYSYLALANYLLEUCYLHISTIDYLARGINYLGLUTAMINYLGLUTAMYLALANYLVALYLASPARTYLALANYLLEUCINE; NEUROTRANSMITTER; PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DENSITY; CELL FUNCTION; CONTROLLED STUDY; DENDRITIC SPINE; DORSAL STRIATAL MEDIUM SPINY NEURON; ENZYME INHIBITION; ENZYME REGULATION; EXCITATORY POSTSYNAPTIC POTENTIAL; FEMALE; GENE OVEREXPRESSION; GENETIC REGULATION; HIPPOCAMPUS; MALE; MOUSE; NERVE CELL EXCITABILITY; NERVE CELL MEMBRANE STEADY POTENTIAL; NEUROTRANSMITTER RELEASE; NONHUMAN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SPINAL CORD NERVE CELL; SYNAPSE; SYNAPTIC TRANSMISSION;

ANIMALS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CORPUS STRIATUM; EXCITATORY POSTSYNAPTIC POTENTIALS; FEMALE; MALE; MICE; MICE, TRANSGENIC; NEURONS; PEPTIDES; RECEPTORS, AMPA; SYNAPTIC TRANSMISSION;

MUS; MUS MUSCULUS;

EID: 84866637875     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0045323     Document Type: Article

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