Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation

Science

Volumn 284, Issue 5421, 1999, Pages 1811-1816

  Shi, Song Hai ^a   Hayashi, Yasunori ^a   Petralia, Ronald S ^b   Zaman, Shahid H ^a   Wenthold, Robert J ^b   Svoboda, Karel ^a   Malinow, Roberto ^a  

^a Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^b NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPA RECEPTOR; GLUTAMATE RECEPTOR; GREEN FLUORESCENT PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; RECEPTOR SUBUNIT;

ARTICLE; CELL STIMULATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DENDRITE; ENZYME ACTIVATION; HIPPOCAMPUS; HUMAN; HUMAN CELL; LONG TERM POTENTIATION; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; BRAIN NERVE CELL; DENDRITIC SPINE; GENETIC TRANSFECTION; NERVE CELL CULTURE; OLIGOMERIZATION;

ANIMALS; CELLS, CULTURED; DENDRITES; ELECTRIC STIMULATION; HIPPOCAMPUS; HUMANS; LONG-TERM POTENTIATION; NEURONAL PLASTICITY; NEURONS; ORGAN CULTURE TECHNIQUES; RATS; RECEPTOR AGGREGATION; RECEPTORS, AMPA; RECEPTORS, N-METHYL-D-ASPARTATE; RECOMBINANT FUSION PROTEINS; SYNAPSES; SYNAPTIC TRANSMISSION; TETANY;

EID: 0033546052     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.284.5421.1811     Document Type: Article

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55. We thank S. Schlesinger for Sindbis virus expression system; P. De Camilli for antibody against synapsin I; C. S. Zucker for antibody to GFP; J. Boulter, S. F. Heinemann, and P. H. Seeburg for cDNA clones; N. Dawkins-Pisani, B. Burbach, and P. O'Brian for technical assistance; and Y.-X. Wang for assistance in the immunogold studies. Y.H. is a recipient of research fellowships from Japan Society for the Promotion of Science and Uehara Memorial Foundation. S.H.Z. was a recipient of Wellcome Trust Fellowship. This study was supported by the NIH (R.M. and K.S.), the Mathers Foundation (R.M.), and the Human Frontier Science Program, Pew, and Whitaker Foundations (K.S).