Postsynaptically silent synapses in single neuron cultures

Neuron

Volumn 21, Issue 6, 1998, Pages 1443-1451

  Gomperts, Stephen N ^a   Rao, Anuradha ^c   Craig, Ann Marie ^c   Malenka, Robert C ^b   Nicoll, Roger A ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPA RECEPTOR; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; HIPPOCAMPUS; IMMUNOCYTOCHEMISTRY; NERVE CELL CULTURE; NERVE CELL NETWORK; NEUROPHYSIOLOGY; NEWBORN; NONHUMAN; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; SYNAPTIC TRANSMISSION;

EID: 0032408313     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(00)80662-5     Document Type: Article

References (23)

1. Bardoni, R., Magherini, P.C., and MacDermott, A.B. (1998). NMDA EPSCs at glutamatergic synapses in the spinal cord dorsal horn of the postnatal rat. J. Neurosci. 18, 6558-6567.
2. Bekkers, J.M., and Stevens, C.F. (1989). NMDA and non-NMDA receptors are co-localized at individual excitatory synapses in cultured rat hippocampus. Nature 341, 230-233.
3. Craig, A.M., Blackstone, C.D., Huganir, R.L., and Banker, G. (1993). The distribution of glutamate receptors in cultured rat hippocampal neurons: postsynaptic clustering of AMPA-selective subunits. Neuron 10, 1055-1068.
4. Durand, G.M., Kovalchuk, Y., and Konnerth, A. (1996). Long-term potentiation and functional synapse induction in developing hippocampus. Nature 381, 71-75.
5. Goda, Y., and Stevens, C.F. (1994). Two components of transmitter release at a central synapse. Proc. Natl. Acad. Sci. USA 91, 12942-12946.
6. Goslin, K., Asmussen, H., and Banker, G. (1998). Rat hippocampal neurons in low-density culture. In Culturing Nerve Cells, Second Edition, G. Banker and K. Goslin, eds. (Cambridge, MA: MIT Press), pp. 339-370.
7. Isaac, J.T.R., Nicoll, R.A., and Malenka, R.C. (1995). Evidence for silent synapses: implications for the expression of LTP. Neuron 15, 427-434.
8. Isaac, J.T.R., Crair, M.C., Nicoll, R.A., and Malenka, R.C. (1997). Silent synapses during development of thalamocortical inputs. Neuron 18, 269-280.
9. Kiyosue, K., Kasai, M., and Taguchi, T. (1997). Selective formation of silent synapses on immature postsynaptic cells in cocultures of chick neurons of different ages. Dev. Brain Res. 99, 201-207.
10. Kullmann, D.M. (1994). Amplitude fluctuations of dual-component EPSCs in hippocampal pyramidal cells: implications for long-term potentiation. Neuron 12, 1111-1120.
11. Kullmann, D.M., and Asztely, F. (1998). Extrasynaptic glutamate spill-over in the hippocampus: evidence and implications. Trends Neurosci. 21, 8-14.
12. Kullmann, D.M., Erdemli, G., and Asztely, F. (1996). LTP of AMPA and NMDA receptor-mediated signals: evidence for presynaptic expression and extrasynaptic glutamate spill-over. Neuron 17, 461-474.
13. Li, P., and Zhuo, M. (1998). Silent glutamatergic synapses and nociception in mammalian spinal cord. Nature 393, 695-698.
14. Liao, D., Hessler, N.A., and Malinow, R. (1995). Activation of postsynaptically silent synapses during pairing-induced LTP in CA1 region of hippocampal slice. Nature 375, 400-404.
15. Lissin, D.V., Gomperts, S.N., Carroll, R.C., Christine, C.W., Kalman, D., Kitamura, M., Hardy, S., Nicoll, R.A., Malenka, R.C., and von Zastrow, M. (1998). Activity differentially regulates the surface expression of synaptic AMPA and NMDA glutamate receptors. Proc. Natl. Acad. Sci. USA 95, 7097-7102.
16. Niu, Y.-P., Xiao, M.-Y., and Wigström, H. (1998). Variability of AMPA and NMDA receptor mediated responses in CA1 pyramidal cells of young rats. Brain Res. 800, 253-259.
17. Nusser, Z., Lujan, R., Laube, G., Roberts, J.D.B., Molar, E., and Somogyi, P. (1998). Cell type and pathway dependence of synaptic AMPA receptor number and variability in the hippocampus. Neuron 21, 545-559.
18. Rao, A., and Craig, A.M. (1997). Activity regulates the synaptic localization of the NMDA receptor in hippocampal neurons. Neuron 19, 801-812.
19. Rao, A., Kim, E., Sheng, M., and Craig, A.M. (1998). Heterogeneity in the molecular composition of excitatory postsynaptic sites during development of hippocampal neurons in culture. J. Neurosci. 18, 1217-1229.
20. Segal, M.M., and Furshpan, E.J. (1990). Epileptiform activity in microcultures containing small numbers of hippocampal neurons. J. Neurophysiol. 64, 1390-1399.
21. Selig, D.K., Hjelmstad, G.O., Herron, C., Nicoll, R.A., and Malenka, R.C. (1995). Independent mechanisms for long-term depression of AMPA and NMDA responses. Neuron 15, 417-426.
22. Tong, G., and Jahr, C.E. (1994). Block of glutamate transporters potentiates postsynaptic excitation. Neuron 13, 1195-1203.
23. Wu, G., Malinow, R., and Cline, H.T. (1996). Maturation of a central glutamatergic synapse. Science 274, 972-976.