메뉴 건너뛰기




Volumn 5, Issue 4, 2012, Pages 509-518

Oxidative stress, nox isoforms and complications of diabetes-potential targets for novel therapies

Author keywords

Cardiovascular disease; Diabetes mellitus; Diabetic nephropathy; NADPH oxidase; Nox isoforms

Indexed keywords

ENZYME INHIBITOR; GKT 136901; GKT 137831; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 3; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4 INHIBITOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 5; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 6; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 7; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE INHIBITOR; UNCLASSIFIED DRUG; VAS 2870; VAS 3947;

EID: 84866068439     PISSN: 19375387     EISSN: 19375395     Source Type: Journal    
DOI: 10.1007/s12265-012-9387-2     Document Type: Article
Times cited : (106)

References (112)
  • 1
    • 77953821528 scopus 로고    scopus 로고
    • Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: A collaborative meta-analysis of 102 prospective studies
    • Emerging Risk Factors Collaboration
    • Emerging Risk Factors Collaboration, Sarwar, N.,Gao, P., Seshasai, S. R., Gobin, R., Kaptoge, S., et al. (2010). Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies. Lancet, 375, 2215-2222.
    • (2010) Lancet , vol.375 , pp. 2215-2222
    • Sarwar, N.1    Gao, P.2    Seshasai, S.R.3    Gobin, R.4    Kaptoge, S.5
  • 2
    • 84872210958 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention. National diabetes fact sheet: national estimates and general information on diabetes and prediabetes in the United States, (2011). Atlanta: Department of Health and Human Services, Centers for Disease Control and Prevention
    • Centers for Disease Control and Prevention. National diabetes fact sheet: national estimates and general information on diabetes and prediabetes in the United States, (2011). Atlanta: Department of Health and Human Services, Centers for Disease Control and Prevention.
  • 3
    • 84859382440 scopus 로고    scopus 로고
    • Clinical practice. Glycemic management of type 2 diabetes mellitus
    • Ismail-Beigi, F. (2012). Clinical practice. Glycemic management of type 2 diabetes mellitus. The New England Journal of Medicine, 366(14), 1319-1327.
    • (2012) The New England Journal of Medicine , vol.366 , Issue.14 , pp. 1319-1327
    • Ismail-Beigi, F.1
  • 6
    • 84878893878 scopus 로고    scopus 로고
    • Acute and chronic fluctuations in blood glucose levels can increase oxidative stress in type 2 diabetes mellitus
    • 2012 May 1. [Epub ahead of print]
    • Chang, C.M., Hsieh, C.J., Huang, J.C., Huang, I.C. (2012). Acute and chronic fluctuations in blood glucose levels can increase oxidative stress in type 2 diabetes mellitus. Acta Diabetologia. 2012 May 1. [Epub ahead of print].
    • (2012) Acta Diabetologia
    • Chang, C.M.1    Hsieh, C.J.2    Huang, J.C.3    Huang, I.C.4
  • 7
    • 84863847452 scopus 로고    scopus 로고
    • Aldose reductase, oxidative stress, and diabetic mellitus
    • Tang, W. H., Martin, K. A., & Hwa, J. (2012). Aldose reductase, oxidative stress, and diabetic mellitus. Frontiers in Pharmacology, 3, 87-90.
    • (2012) Frontiers in Pharmacology , vol.3 , pp. 87-90
    • Tang, W.H.1    Martin, K.A.2    Hwa, J.3
  • 8
    • 84865657612 scopus 로고    scopus 로고
    • Oxidative stress in the cardiorenal metabolic syndrome
    • May 13. [Epub ahead of print]
    • Whaley-Connell, A., Sowers, J.R. (2012). Oxidative stress in the cardiorenal metabolic syndrome. Current Hypertension Reports. May 13. [Epub ahead of print].
    • (2012) Current Hypertension Reports
    • Whaley-Connell, A.1    Sowers, J.R.2
  • 10
    • 30344486998 scopus 로고    scopus 로고
    • Oxidative stress and diabetic cardiovascular complications
    • Jay, D., Hitomi, H., & Griendling, K. K. (2006). Oxidative stress and diabetic cardiovascular complications. Free Radical Biology & Medicine, 40(2), 183-192.
    • (2006) Free Radical Biology & Medicine , vol.40 , Issue.2 , pp. 183-192
    • Jay, D.1    Hitomi, H.2    Griendling, K.K.3
  • 11
    • 81755177460 scopus 로고    scopus 로고
    • The renin-angiotensin-aldosterone system and glucose homeostasis
    • Luther, J. M., & Brown, N. (2011). The renin-angiotensin-aldosterone system and glucose homeostasis. Trends in Pharmacological Sciences, 32(12), 734-739.
    • (2011) Trends in Pharmacological Sciences , vol.32 , Issue.12 , pp. 734-739
    • Luther, J.M.1    Brown, N.2
  • 12
    • 77950915621 scopus 로고    scopus 로고
    • Oxidative stress and diabetic cardiovascular disorders: Roles of mitochondria and NADPH oxidase
    • Shen, G. X. (2010). Oxidative stress and diabetic cardiovascular disorders: roles of mitochondria and NADPH oxidase. Canadian Journal of Physiology and Pharmacology, 88(3), 241-248.
    • (2010) Canadian Journal of Physiology and Pharmacology , vol.88 , Issue.3 , pp. 241-248
    • Shen, G.X.1
  • 13
    • 33847346061 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase uncoupling impairs endothelial progenitor cell mobilization and function in diabetes
    • Thum, T., Fraccarollo, D., Schultheiss, M., Froese, S., Galuppo, P., Widder, J. D., et al. (2007). Endothelial nitric oxide synthase uncoupling impairs endothelial progenitor cell mobilization and function in diabetes. Diabetes, 56(3), 666-674.
    • (2007) Diabetes , vol.56 , Issue.3 , pp. 666-674
    • Thum, T.1    Fraccarollo, D.2    Schultheiss, M.3    Froese, S.4    Galuppo, P.5    Widder, J.D.6
  • 16
    • 42549085269 scopus 로고    scopus 로고
    • NADPH oxidase-derived reactive oxygen species in the regulation of endothelial phenotype
    • Dworakowski, R., Alom-Ruiz, S. P., & Shah, A. M. (2008). NADPH oxidase-derived reactive oxygen species in the regulation of endothelial phenotype. Pharmacological Reports, 60(1), 21-28.
    • (2008) Pharmacological Reports , vol.60 , Issue.1 , pp. 21-28
    • Dworakowski, R.1    Alom-Ruiz, S.P.2    Shah, A.M.3
  • 17
    • 80054704273 scopus 로고    scopus 로고
    • NADPH oxidases in cardiovascular disease: Insights from in vivo models and clinical studies
    • Sirker, A., Zhang, M., & Shah, A. M. (2011). NADPH oxidases in cardiovascular disease: insights from in vivo models and clinical studies. Basic Research in Cardiology, 106(5), 735-4.
    • (2011) Basic Research in Cardiology , vol.106 , Issue.5 , pp. 735-744
    • Sirker, A.1    Zhang, M.2    Shah, A.M.3
  • 18
    • 84857610644 scopus 로고    scopus 로고
    • The NOX-ROS connection: Targeting Nox1 control of N-cadherin shedding in vascular smooth muscle cells
    • Redmond, E. M., & Cahill, P. A. (2012). The NOX-ROS connection: targeting Nox1 control of N-cadherin shedding in vascular smooth muscle cells. Cardiovascular Research, 93(3), 386-390.
    • (2012) Cardiovascular Research , vol.93 , Issue.3 , pp. 386-390
    • Redmond, E.M.1    Cahill, P.A.2
  • 20
    • 84859042805 scopus 로고    scopus 로고
    • Activation of thromboxane receptor modulates interleukin-1β-induced monocyte adhesion - A novel role of Nox1
    • Bayat, H., Schröder, K., Pimentel, D. R., Brandes, R. P., Verbeuren, T. J., Cohen, R. A., et al. (2012). Activation of thromboxane receptor modulates interleukin-1β-induced monocyte adhesion - a novel role of Nox1. Free Radical Biology&Medicine, 52(9), 1760-1766.
    • (2012) Free Radical Biology&Medicine , vol.52 , Issue.9 , pp. 1760-1766
    • Bayat, H.1    Schröder, K.2    Pimentel, D.R.3    Brandes, R.P.4    Verbeuren, T.J.5    Cohen, R.A.6
  • 21
    • 38549161561 scopus 로고    scopus 로고
    • Renal redox-sensitive signaling, but not blood pressure, is attenuated by Nox1 knockout in angiotensin II-dependent chronic hypertension
    • Yogi, A., Mercure, C., Touyz, J., Callera, G. E., Montezano, A. C., Aranha, A. B., et al. (2008). Renal redox-sensitive signaling, but not blood pressure, is attenuated by Nox1 knockout in angiotensin II-dependent chronic hypertension. Hypertension, 51(2), 500-506.
    • (2008) Hypertension , vol.51 , Issue.2 , pp. 500-506
    • Yogi, A.1    Mercure, C.2    Touyz, J.3    Callera, G.E.4    Montezano, A.C.5    Aranha, A.B.6
  • 22
    • 79955091590 scopus 로고    scopus 로고
    • The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91(phox) mediate hepatic fibrosis in mice
    • Paik, Y. H., Iwaisako, K., Seki, E., Inokuchi, S., Schnabl, B., Osterreicher, C. H., et al. (2011). The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91(phox) mediate hepatic fibrosis in mice. Hepatology, 53(5), 1730-1741.
    • (2011) Hepatology , vol.53 , Issue.5 , pp. 1730-1741
    • Paik, Y.H.1    Iwaisako, K.2    Seki, E.3    Inokuchi, S.4    Schnabl, B.5    Osterreicher, C.H.6
  • 25
    • 84866134987 scopus 로고    scopus 로고
    • The p47(phox)- and NADPH oxidase organiser 1 (NOXO1)-dependent activation of NADPH oxidase 1 (NOX1) mediates endothelial nitric oxide synthase (eNOS) uncoupling and endothelial dysfunction in a streptozotocin-induced murine model of diabetes
    • Youn, J.Y., Gao, L., Cai, H. (2012). The p47(phox)- and NADPH oxidase organiser 1 (NOXO1)-dependent activation of NADPH oxidase 1 (NOX1) mediates endothelial nitric oxide synthase (eNOS) uncoupling and endothelial dysfunction in a streptozotocin-induced murine model of diabetes. Diabetologia 55, 2069-2079.
    • (2012) Diabetologia , vol.55 , pp. 2069-2079
    • Youn, J.Y.1    Gao, L.2    Cai, H.3
  • 26
    • 4644363091 scopus 로고    scopus 로고
    • Gene transfer of NAD(P)H oxidase inhibitor to the vascular adventitia attenuates medial smooth muscle hypertrophy
    • Liu, J., Ormsby, A., Oja-Tebbe, N., & Pagano, P. J. (2004). Gene transfer of NAD(P)H oxidase inhibitor to the vascular adventitia attenuates medial smooth muscle hypertrophy. Circulation Research, 95(6), 587-594.
    • (2004) Circulation Research , vol.95 , Issue.6 , pp. 587-594
    • Liu, J.1    Ormsby, A.2    Oja-Tebbe, N.3    Pagano, P.J.4
  • 27
    • 15744384153 scopus 로고    scopus 로고
    • Angiotensin II-dependent chronic hypertension and cardiac hypertrophy in mice do not require gp91phox-containing NADPH oxidase
    • Touyz, R. M., Mercure, C., He, Y., Javeshghani, D., Yao, G., & Reudelhuber, T. (2005). Angiotensin II-dependent chronic hypertension and cardiac hypertrophy in mice do not require gp91phox-containing NADPH oxidase. Hypertension, 45, 530-537.
    • (2005) Hypertension , vol.45 , pp. 530-537
    • Touyz, R.M.1    Mercure, C.2    He, Y.3    Javeshghani, D.4    Yao, G.5    Reudelhuber, T.6
  • 28
    • 80755184724 scopus 로고    scopus 로고
    • Increased phagocyte-like NADPH oxidase and ROS generation in type 2 diabetic ZDF rat and human islets: Role of Rac1-JNK1/2 signaling pathway in mitochondrial dysregulation in the diabetic islet
    • Syed, I., Kyathanahalli, C. N., Jayaram, B., Govind, S., Rhodes, C. J., Kowluru, R. A., et al. (2011). Increased phagocyte-like NADPH oxidase and ROS generation in type 2 diabetic ZDF rat and human islets: role of Rac1-JNK1/2 signaling pathway in mitochondrial dysregulation in the diabetic islet. Diabetes, 60 (11), 2843-2852.
    • (2011) Diabetes , vol.60 , Issue.11 , pp. 2843-2852
    • Syed, I.1    Kyathanahalli, C.N.2    Jayaram, B.3    Govind, S.4    Rhodes, C.J.5    Kowluru, R.A.6
  • 29
    • 79951870207 scopus 로고    scopus 로고
    • NOX3 NADPH oxidase couples transient receptor potential vanilloid 1 to signal transducer and activator of transcription 1-mediated inflammation and hearing loss
    • Mukherjea, D., Jajoo, S., Sheehan, K., Kaur, T., Sheth, S., Bunch, J., et al. (2011). NOX3 NADPH oxidase couples transient receptor potential vanilloid 1 to signal transducer and activator of transcription 1-mediated inflammation and hearing loss. Antioxidants & Redox Signaling, 14(6), 999-1010.
    • (2011) Antioxidants & Redox Signaling , vol.14 , Issue.6 , pp. 999-1010
    • Mukherjea, D.1    Jajoo, S.2    Sheehan, K.3    Kaur, T.4    Sheth, S.5    Bunch, J.6
  • 30
    • 33847279372 scopus 로고    scopus 로고
    • A genome-wide search for linkage to renal function phenotypes in West Africans with type 2 diabetes
    • Chen, G., Adeyemo, A. A., Zhou, J., Chen, Y., Doumatey, A., Lashley, K., et al. (2007). A genome-wide search for linkage to renal function phenotypes in West Africans with type 2 diabetes. American Journal of Kidney Diseases, 49(3), 394-400.
    • (2007) American Journal of Kidney Diseases , vol.49 , Issue.3 , pp. 394-400
    • Chen, G.1    Adeyemo, A.A.2    Zhou, J.3    Chen, Y.4    Doumatey, A.5    Lashley, K.6
  • 31
    • 33748169328 scopus 로고    scopus 로고
    • Oxidative stress mediates the stimulation of sympathetic nerve activity in the phenol renal injury model of hypertension
    • Ye, S., Zhong, H., Yanamadala, S., & Campese, V. M. (2006). Oxidative stress mediates the stimulation of sympathetic nerve activity in the phenol renal injury model of hypertension. Hypertension, 48(2), 309-132.
    • (2006) Hypertension , vol.48 , Issue.2 , pp. 309-132
    • Ye, S.1    Zhong, H.2    Yanamadala, S.3    Campese, V.M.4
  • 32
    • 84866117902 scopus 로고    scopus 로고
    • Opportunity Nox: The future of NADPH oxidases as therapeutic targets in cardiovascular disease
    • doi: 10.1111
    • Streeter, J., Thiel, W., Brieger, K., Miller, Jr F. J. (2012). Opportunity Nox: the future of NADPH oxidases as therapeutic targets in cardiovascular disease. Cardiovascular Therapeutics. doi: 10.1111.
    • (2012) Cardiovascular Therapeutics
    • Streeter, J.1    Thiel, W.2    Brieger, K.3    Miller Jr., F.J.4
  • 33
    • 84555188779 scopus 로고    scopus 로고
    • Hyperglycemia enhances IGF-I-stimulated Src activation via increasing Nox4-derived reactive oxygen species in a PKCζ-dependent manner in vascular smooth muscle cells
    • Xi, G., Shen, X., Maile, L. A.,Wai, C., Gollahon, K., & Clemmons, D. R. (2012). Hyperglycemia enhances IGF-I-stimulated Src activation via increasing Nox4-derived reactive oxygen species in a PKCζ-dependent manner in vascular smooth muscle cells. Diabetes, 61(1), 104-113.
    • (2012) Diabetes , vol.61 , Issue.1 , pp. 104-113
    • Xi, G.1    Shen, X.2    Maile, A.3    Wai, L.C.4    Gollahon, K.5    Clemmons, D.R.6
  • 34
    • 70349316712 scopus 로고    scopus 로고
    • Nox5 and the regulation of cellular function
    • Fulton, D. J. (2009). Nox5 and the regulation of cellular function. Antioxidants & Redox Signaling, 11(10), 2443-2452.
    • (2009) Antioxidants & Redox Signaling , vol.11 , Issue.10 , pp. 2443-2452
    • Fulton, D.J.1
  • 35
    • 69249246990 scopus 로고    scopus 로고
    • Poldip2, a novel regulator of Nox4 and cytoskeletal integrity in vascular smooth muscle cells
    • Lyle, A. N., Deshpande, N. N., Taniyama, Y., Seidel-Rogol, B., Pounkova, L., Du, P., et al. (2009). Poldip2, a novel regulator of Nox4 and cytoskeletal integrity in vascular smooth muscle cells. Circulation Research, 105(3), 249-259.
    • (2009) Circulation Research , vol.105 , Issue.3 , pp. 249-259
    • Lyle, A.N.1    Deshpande, N.N.2    Taniyama, Y.3    Seidel-Rogol, B.4    Pounkova, L.5    Du, P.6
  • 41
    • 77958495432 scopus 로고    scopus 로고
    • Upregulation of Nox4 by TGF{beta}1 oxidizes SERCA and inhibits NO in arterial smooth muscle of the prediabetic Zucker rat
    • Tong, X., Hou, X., Jourd'heuil, D., Weisbrod, R. M., & Cohen, R. A. (2010). Upregulation of Nox4 by TGF{beta}1 oxidizes SERCA and inhibits NO in arterial smooth muscle of the prediabetic Zucker rat. Circulation Research, 107, 975-983.
    • (2010) Circulation Research , vol.107 , pp. 975-983
    • Tong, X.1    Hou, X.2    Jourd'Heuil, D.3    Weisbrod, R.M.4    Cohen, R.A.5
  • 42
    • 84862776887 scopus 로고    scopus 로고
    • NOX4 pathway as a source of selective insulin resistance and responsiveness
    • Wu, X., & Williams, K. J. (2012). NOX4 pathway as a source of selective insulin resistance and responsiveness. Arteriosclerosis, Thrombosis, and Vascular Biology, 32(5), 1236-1245.
    • (2012) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.32 , Issue.5 , pp. 1236-1245
    • Wu, X.1    Williams, K.J.2
  • 44
    • 79954546899 scopus 로고    scopus 로고
    • High glucose concentration affects the oxidant-antioxidant balance in cultured mouse podocytes
    • Piwkowska, A., Rogacka, D., Audzeyenka, I., Jankowski, M., & Angielski, S. (2011). High glucose concentration affects the oxidant-antioxidant balance in cultured mouse podocytes. Journal of Cellular Biochemistry, 112(6), 1661-1672.
    • (2011) Journal of Cellular Biochemistry , vol.112 , Issue.6 , pp. 1661-1672
    • Piwkowska, A.1    Rogacka, D.2    Audzeyenka, I.3    Jankowski, M.4    Angielski, S.5
  • 45
    • 78649913769 scopus 로고    scopus 로고
    • Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney: Implications in type 2 diabetic nephropathy
    • Sedeek, M., Callera, G., Montezano, A., Gutsol, A., Heitz, F., Szyndralewiez, C., et al. (2010). Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney: implications in type 2 diabetic nephropathy. American Journal of Physiology. Renal Physiology, 299(6), F1348-F1358.
    • (2010) American Journal of Physiology. Renal Physiology , vol.299 , Issue.6
    • Sedeek, M.1    Callera, G.2    Montezano, A.3    Gutsol, A.4    Heitz, F.5    Szyndralewiez, C.6
  • 48
    • 84858435562 scopus 로고    scopus 로고
    • Positive regulation of NADPH oxidase 5 by proinflammatory-related mechanisms in human aortic smooth muscle cells
    • Manea, A., Manea, S. A., Florea, I. C., Luca, C. M., & Raicu, M. (2012). Positive regulation of NADPH oxidase 5 by proinflammatory-related mechanisms in human aortic smooth muscle cells. Free Radical Biology & Medicine, 52(9), 1497-1507.
    • (2012) Free Radical Biology & Medicine , vol.52 , Issue.9 , pp. 1497-1507
    • Manea, A.1    Manea, S.A.2    Florea, I.C.3    Luca, C.M.4    Raicu, M.5
  • 49
    • 84861637163 scopus 로고    scopus 로고
    • NOX5 expression is increased in intramyocardial blood vessels and cardiomyocytes after acute myocardial infarction in humans
    • Hahn, N. E., Meischl, C., Kawahara, T., Musters, R. J., Verhoef, V. M., van der Velden, J., et al. (2012). NOX5 expression is increased in intramyocardial blood vessels and cardiomyocytes after acute myocardial infarction in humans. American Journal of Pathology, 180(6), 2222-2229.
    • (2012) American Journal of Pathology , vol.180 , Issue.6 , pp. 2222-2229
    • Hahn, N.E.1    Meischl, C.2    Kawahara, T.3    Musters, R.J.4    Verhoef, V.M.5    Van Der Velden, J.6
  • 52
    • 0032543872 scopus 로고    scopus 로고
    • Pathogenesis, prevention, and treatment of diabetic nephropathy
    • Cooper, M. E. (1998). Pathogenesis, prevention, and treatment of diabetic nephropathy. Lancet, 352(9123), 213-219.
    • (1998) Lancet , vol.352 , Issue.9123 , pp. 213-219
    • Cooper, M.E.1
  • 53
    • 48249085391 scopus 로고    scopus 로고
    • Oxidative stress as a major culprit in kidney disease in diabetes
    • Forbes, J. M., Coughlan, M. T., & Cooper, M. E. (2008). Oxidative stress as a major culprit in kidney disease in diabetes. Diabetes, 57(6), 1446-1454.
    • (2008) Diabetes , vol.57 , Issue.6 , pp. 1446-1454
    • Forbes, J.M.1    Coughlan, M.T.2    Cooper, M.E.3
  • 54
    • 65549157823 scopus 로고    scopus 로고
    • Mechanisms of podocyte injury in diabetes: Role of cytochrome P450 and NADPH oxidases
    • Eid, A. A., Gorin, Y., Faff, B. M., Maalouf, R., Barnes, J. L., Block, K., et al. (2009). Mechanisms of podocyte injury in diabetes: role of cytochrome P450 and NADPH oxidases. Diabetes, 58(5), 1201-1211.
    • (2009) Diabetes , vol.58 , Issue.5 , pp. 1201-1211
    • Eid, A.A.1    Gorin, Y.2    Faff, B.M.3    Maalouf, R.4    Barnes, J.L.5    Block, K.6
  • 55
    • 0042864155 scopus 로고    scopus 로고
    • Increased expression of NAD(P)H oxidase subunits, NOX4 and p22phox, in the kidney of streptozotocin-induced diabetic rats and its reversibility by interventive insulin treatment
    • Etoh, T., Inoguchi, T., Kakimoto, M., Sonoda, N., Kobayashi, K., Kuroda, J., et al. (2003). Increased expression of NAD(P)H oxidase subunits, NOX4 and p22phox, in the kidney of streptozotocin-induced diabetic rats and its reversibility by interventive insulin treatment. Diabetologia, 46(10), 1428-1437.
    • (2003) Diabetologia , vol.46 , Issue.10 , pp. 1428-1437
    • Etoh, T.1    Inoguchi, T.2    Kakimoto, M.3    Sonoda, N.4    Kobayashi, K.5    Kuroda, J.6
  • 57
    • 0141755311 scopus 로고    scopus 로고
    • Translocation of glomerular p47phox and p67phox by protein kinase C-beta activation is required for oxidative stress in diabetic nephropathy
    • Kitada, M., Koya, D., Sugimoto, T., Isono, M., Araki, S., Kashiwagi, A., et al. (2003). Translocation of glomerular p47phox and p67phox by protein kinase C-beta activation is required for oxidative stress in diabetic nephropathy. Diabetes, 52(10), 2603-2614.
    • (2003) Diabetes , vol.52 , Issue.10 , pp. 2603-2614
    • Kitada, M.1    Koya, D.2    Sugimoto, T.3    Isono, M.4    Araki, S.5    Kashiwagi, A.6
  • 58
    • 33845522286 scopus 로고    scopus 로고
    • Reduction of diabetes-induced oxidative stress, fibrotic cytokine expression, and renal dysfunction in protein kinase Cbeta-null mice
    • Ohshiro, Y., Ma, R. C., Yasuda, Y., Hiraoka-Yamamoto, J., Clermont, A. C., Isshiki, K., et al. (2006). Reduction of diabetes-induced oxidative stress, fibrotic cytokine expression, and renal dysfunction in protein kinase Cbeta-null mice. Diabetes, 55(11), 3112-3120.
    • (2006) Diabetes , vol.55 , Issue.11 , pp. 3112-3120
    • Ohshiro, Y.1    Ma, R.C.2    Yasuda, Y.3    Hiraoka-Yamamoto, J.4    Clermont, A.C.5    Isshiki, K.6
  • 59
    • 77749264564 scopus 로고    scopus 로고
    • AGER1 regulates endothelial cell NADPH oxidase-dependent oxidant stress via PKC-delta: Implications for vascular disease
    • Cai, W., Torreggiani, M., Zhu, L., Chen, X., He, J. C., Striker, G. E., et al. (2010). AGER1 regulates endothelial cell NADPH oxidase-dependent oxidant stress via PKC-delta: implications for vascular disease. American Journal of Physiology. Cell Physiology, 298(3), C624-C634.
    • (2010) American Journal of Physiology. Cell Physiology , vol.298 , Issue.3
    • Cai, W.1    Torreggiani, M.2    Zhu, L.3    Chen, X.4    He, J.C.5    Striker, G.E.6
  • 60
  • 62
    • 0037369404 scopus 로고    scopus 로고
    • Melatonin reduces renal interstitial inflammation and improves hypertension in spontaneously hypertensive rats
    • Nava, M., Quiroz, Y., Vaziri, N., & Rodriguez-Iturbe, B. (2003). Melatonin reduces renal interstitial inflammation and improves hypertension in spontaneously hypertensive rats. American Journal of Physiology. Renal Physiology, 284(3), F447-F454.
    • (2003) American Journal of Physiology. Renal Physiology , vol.284 , Issue.3
    • Nava, M.1    Quiroz, Y.2    Vaziri, N.3    Rodriguez-Iturbe, B.4
  • 63
    • 0036209325 scopus 로고    scopus 로고
    • Role of high glucose-induced nuclear factor-kappaB activation in monocyte chemoattractant protein-1 expression by mesangial cells
    • Ha, H., Yu, M. R., Choi, Y. J., Kitamura, M., & Lee, H. B. (2002). Role of high glucose-induced nuclear factor-kappaB activation in monocyte chemoattractant protein-1 expression by mesangial cells. Journal of the American Society of Nephrology, 13(4), 894-902.
    • (2002) Journal of the American Society of Nephrology , vol.13 , Issue.4 , pp. 894-902
    • Ha, H.1    Yu, M.R.2    Choi, Y.J.3    Kitamura, M.4    Lee, H.B.5
  • 66
    • 33644783770 scopus 로고    scopus 로고
    • Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy
    • Susztak, K., Raff, A. C., Schiffer, M., & Böttinger, E. P. (2006). Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy. Diabetes, 55(1), 225-233.
    • (2006) Diabetes , vol.55 , Issue.1 , pp. 225-233
    • Susztak, K.1    Raff, A.C.2    Schiffer, M.3    Böttinger, E.P.4
  • 67
    • 84859030420 scopus 로고    scopus 로고
    • Global prevalence and major risk factors of diabetic retinopathy
    • Meta-Analysis for Eye Disease (META-EYE) Study Group.
    • Yau, J. W., Rogers, S. L., Kawasaki, R., Lamoureux, E. L., Kowalski, J. W., Bek, T., Wong, T. Y., & Meta-Analysis for Eye Disease (META-EYE) Study Group. (2012). Global prevalence and major risk factors of diabetic retinopathy. Diabetes Care, 35(3), 556-564.
    • (2012) Diabetes Care , vol.35 , Issue.3 , pp. 556-564
    • Yau, J.W.1    Rogers, S.L.2    Kawasaki, R.3    Lamoureux, E.L.4    Kowalski, J.W.5    Bek, T.6    Wong, T.Y.7
  • 68
    • 0042932653 scopus 로고    scopus 로고
    • Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales
    • Wilkinson, C. P., Ferris, F. L., 3rd, Klein, R. E., Lee, P. P., Agardh, C. D., Davis, M., et al. (2003). Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales. Ophthalmology, 110, 1677-1682.
    • (2003) Ophthalmology , vol.110 , pp. 1677-1682
    • Wilkinson, C.P.1    Ferris III, F.L.2    Klein, R.E.3    Lee, P.P.4    Agardh, C.D.5    Davis, M.6
  • 69
    • 80053471739 scopus 로고    scopus 로고
    • Hypoxia and oxidative stress in the causation of diabetic retinopathy
    • Arden, G. B., & Sivaprasad, S. (2011). Hypoxia and oxidative stress in the causation of diabetic retinopathy. Current Diabetes Reviews, 7, 291-304.
    • (2011) Current Diabetes Reviews , vol.7 , pp. 291-304
    • Arden, G.B.1    Sivaprasad, S.2
  • 71
    • 77953200258 scopus 로고    scopus 로고
    • Inhibition of reactive oxygen species by Lovastatin downregulates vascular endothelial growth factor expression and ameliorates blood-retinal barrier breakdown in db/db mice: Role of NADPH oxidase 4
    • Li, J., Wang, J. J., Yu, Q., Chen, K., Mahadev, K., & Zhang, S. X. (2010). Inhibition of reactive oxygen species by Lovastatin downregulates vascular endothelial growth factor expression and ameliorates blood-retinal barrier breakdown in db/db mice: role of NADPH oxidase 4. Diabetes, 59, 1528-1538.
    • (2010) Diabetes , vol.59 , pp. 1528-1538
    • Li, J.1    Wang, J.J.2    Yu, Q.3    Chen, K.4    Mahadev, K.5    Zhang, S.X.6
  • 72
    • 84861155984 scopus 로고    scopus 로고
    • Neuronal NAD(P)H oxidases contribute to ROS production and mediate RGC death after ischemia
    • Dvoriantchikova et al. (2012) Neuronal NAD(P)H oxidases contribute to ROS production and mediate RGC death after ischemia. Investigative Ophthalmology & Visual Science 53, 2823-2830.
    • (2012) Investigative Ophthalmology & Visual Science , vol.53 , pp. 2823-2830
    • Dvoriantchikova1
  • 73
    • 77952299343 scopus 로고    scopus 로고
    • Rod and cone photoreceptor cells produce ROS in response to stress in a live retinal explant system
    • Bhatt, L., Groeger, G., McDermott, K., & Cotter, T. G. (2010). Rod and cone photoreceptor cells produce ROS in response to stress in a live retinal explant system. Molecular Vision, 16, 283-293.
    • (2010) Molecular Vision , vol.16 , pp. 283-293
    • Bhatt, L.1    Groeger, G.2    McDermott, K.3    Cotter, T.G.4
  • 76
    • 84856219135 scopus 로고    scopus 로고
    • Cellular crosstalk between TNF-alpha, NADPH oxidase, PKCbeta2, and C2GNT in human leukocytes
    • Tarr, J. M., Ding, N., Kaul, K., Antonell, A., Perez-Jurado, L. A., & Chibber, R. (2012). Cellular crosstalk between TNF-alpha, NADPH oxidase, PKCbeta2, and C2GNT in human leukocytes. Cellular Signalling, 24, 873-878.
    • (2012) Cellular Signalling , vol.24 , pp. 873-878
    • Tarr, J.M.1    Ding, N.2    Kaul, K.3    Antonell, A.4    Perez-Jurado, L.A.5    Chibber, R.6
  • 78
    • 79951539813 scopus 로고    scopus 로고
    • Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARalpha mediated mechanism
    • Garrido-Urbani, S., Jemelin, S., Deffert, C., Carnesecchi, S., Basset, O., Szyndralewiez, C., et al. (2011). Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARalpha mediated mechanism. PLoS One, 6, e14665.
    • (2011) PLoS One , vol.6
    • Garrido-Urbani, S.1    Jemelin, S.2    Deffert, C.3    Carnesecchi, S.4    Basset, O.5    Szyndralewiez, C.6
  • 80
    • 34250660448 scopus 로고    scopus 로고
    • Inhibition of NAD(P)H oxidase reduces apoptosis and avascular retina in an animal model of retinopathy of prematurity
    • Saito, Y., Geisen, P., Uppal, A., & Hartnett, M. E. (2007). Inhibition of NAD(P)H oxidase reduces apoptosis and avascular retina in an animal model of retinopathy of prematurity. Molecular Vision, 13, 840-853.
    • (2007) Molecular Vision , vol.13 , pp. 840-853
    • Saito, Y.1    Geisen, P.2    Uppal, A.3    Hartnett, M.E.4
  • 83
    • 59449102868 scopus 로고    scopus 로고
    • Suppression of retinal peroxisome proliferator-activated receptor gamma in experimental diabetes and oxygen-induced retinopathy: Role of NADPH oxidase
    • Tawfik, A., Sanders, T., Kahook, K., AkeeL, S., Elmarakby, A., & Al-Shabrawey, M. (2009). Suppression of retinal peroxisome proliferator- activated receptor gamma in experimental diabetes and oxygen-induced retinopathy: role of NADPH oxidase. Investigative Ophthalmology and Visual Science, 50, 878-884.
    • (2009) Investigative Ophthalmology and Visual Science , vol.50 , pp. 878-884
    • Tawfik, A.1    Sanders, T.2    Kahook, K.3    Akeel, S.4    Elmarakby, A.5    Al-Shabrawey, M.6
  • 84
    • 77952933119 scopus 로고    scopus 로고
    • RILLKKMPSV influences the vasculature, neurons and glia, and (pro)renin receptor expression in the retina
    • Wilkinson-Berka, J. L., Heine, R., Tan, G., Cooper, M. E., Hatzopoulos, K. M., Fletcher, E. L., et al. (2010). RILLKKMPSV influences the vasculature, neurons and glia, and (pro)renin receptor expression in the retina. Hypertension, 55, 1454-1460.
    • (2010) Hypertension , vol.55 , pp. 1454-1460
    • Wilkinson-Berka, J.L.1    Heine, R.2    Tan, G.3    Cooper, M.E.4    Hatzopoulos, K.M.5    Fletcher, E.L.6
  • 87
    • 53849107495 scopus 로고    scopus 로고
    • Involvement of angiotensin II-dependent vascular endothelial growth factor gene expression via NADPH oxidase in the retina in a type 2 diabetic rat model
    • Fukumoto, M., Takai, S., Ishizaki, E., Sugiyama, T., Oku, H., Jin, D., et al. (2008). Involvement of angiotensin II-dependent vascular endothelial growth factor gene expression via NADPH oxidase in the retina in a type 2 diabetic rat model. Current Eye Research, 33, 885-891.
    • (2008) Current Eye Research , vol.33 , pp. 885-891
    • Fukumoto, M.1    Takai, S.2    Ishizaki, E.3    Sugiyama, T.4    Oku, H.5    Jin, D.6
  • 88
    • 33749873445 scopus 로고    scopus 로고
    • Activation of nicotinamide adenine dinucleotide phosphate (reduced form) oxidase by advanced glycation end products links oxidative stress to altered retinal vascular endothelial growth factor expression
    • Li, L., & Renier, G. (2006). Activation of nicotinamide adenine dinucleotide phosphate (reduced form) oxidase by advanced glycation end products links oxidative stress to altered retinal vascular endothelial growth factor expression. Metabolism, 55, 1516-1523.
    • (2006) Metabolism , vol.55 , pp. 1516-1523
    • Li, L.1    Renier, G.2
  • 89
    • 33746019939 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor inhibits advanced glycation end product-induced retinal vascular hyperpermeability by blocking reactive oxygen species-mediated vascular endothelial growth factor expression
    • Yamagishi, S., Nakamura, K., Matsui, T., Inagaki, Y., Takenaka, K., Jinnouchi, Y., et al. (2006). Pigment epithelium-derived factor inhibits advanced glycation end product-induced retinal vascular hyperpermeability by blocking reactive oxygen species-mediated vascular endothelial growth factor expression. Journal of Biological Chemistry, 281(29), 20213-20220.
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.29 , pp. 20213-20220
    • Yamagishi, S.1    Nakamura, K.2    Matsui, T.3    Inagaki, Y.4    Takenaka, K.5    Jinnouchi, Y.6
  • 90
    • 78650044928 scopus 로고    scopus 로고
    • Candesartan attenuates diabetic retinal vascular pathology by restoring glyoxalase-I function
    • Miller, A. G., Tan, G., Binger, K. J., Pickering, R. J., Thomas, M. C., Nagaraj, R. H., et al. (2010). Candesartan attenuates diabetic retinal vascular pathology by restoring glyoxalase-I function. Diabetes, 59, 3208-3215.
    • (2010) Diabetes , vol.59 , pp. 3208-3215
    • Miller, A.G.1    Tan, G.2    Binger, K.J.3    Pickering, R.J.4    Thomas, M.C.5    Nagaraj, R.H.6
  • 92
  • 93
    • 27444447834 scopus 로고    scopus 로고
    • Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice
    • Dikalova, A., Clempus, R., Lassegue, B., Cheng, G., Mccoy, J., Dikalov, S., et al. (2005). Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice. Circulation, 112, 2668-2676.
    • (2005) Circulation , vol.112 , pp. 2668-2676
    • Dikalova, A.1    Clempus, R.2    Lassegue, B.3    Cheng, G.4    McCoy, J.5    Dikalov, S.6
  • 94
    • 78349257749 scopus 로고    scopus 로고
    • Protein tyrosine phosphatase PTPepsilonM negatively regulates PDGF beta-receptor signaling induced by high glucose and PDGF in vascular smooth muscle cells
    • Shimizu, H., Nakagawa, Y., Murakami, C., Aoki, N., Kim- Mitsuyama, S., & Miyazaki, H. (2010). Protein tyrosine phosphatase PTPepsilonM negatively regulates PDGF beta-receptor signaling induced by high glucose and PDGF in vascular smooth muscle cells. American Journal of Physiology. Cell Physiology, 299(5), C1144-C1145.
    • (2010) American Journal of Physiology. Cell Physiology , vol.299 , Issue.5
    • Shimizu, H.1    Nakagawa, Y.2    Murakami, C.3    Aoki, N.4    Kim- Mitsuyama, S.5    Miyazaki, H.6
  • 95
    • 79251591938 scopus 로고    scopus 로고
    • Ultrastructural analysis and electron microscopic localization of Nox4 in healthy and atherosclerotic human aorta
    • Perrotta, I., Sciangula, A., Perrotta, E., Donato, G., & Cassese, M. (2011). Ultrastructural analysis and electron microscopic localization of Nox4 in healthy and atherosclerotic human aorta. Ultrastructural Pathology, 35(1), 1-6.
    • (2011) Ultrastructural Pathology , vol.35 , Issue.1 , pp. 1-6
    • Perrotta, I.1    Sciangula, A.2    Perrotta, E.3    Donato, G.4    Cassese, M.5
  • 96
    • 79957933001 scopus 로고    scopus 로고
    • Tyrphostin AG490 reduces NAPDH oxidase activity and expression in the aorta of hypercholesterolemic apolipoprotein Edeficient mice
    • Fenyo, I. M., Florea, I. C., Raicu, M., & Manea, A. (2011). Tyrphostin AG490 reduces NAPDH oxidase activity and expression in the aorta of hypercholesterolemic apolipoprotein Edeficient mice. Vascular Pharmacology, 54(3-6), 100-106.
    • (2011) Vascular Pharmacology , vol.54 , Issue.3-6 , pp. 100-106
    • Fenyo, I.M.1    Florea, I.C.2    Raicu, M.3    Manea, A.4
  • 98
    • 27444441677 scopus 로고    scopus 로고
    • Nox1 is involved in angiotensin IImediated hypertension: A study in Nox1-deficient mice
    • Matsuno, K., Yamada, H., Iwata, K., Jin, D., Katsuyama, M., Matsuki, M., et al. (2005). Nox1 is involved in angiotensin IImediated hypertension: a study in Nox1-deficient mice. Circulation, 112, 2677-2685.
    • (2005) Circulation , vol.112 , pp. 2677-2685
    • Matsuno, K.1    Yamada, H.2    Iwata, K.3    Jin, D.4    Katsuyama, M.5    Matsuki, M.6
  • 99
    • 0026722306 scopus 로고
    • Effect of apocynin on the induction of ulcerative lesions in rat skin injected with tubercle bacteria
    • Hart, B. A., Elferink, J. G., & Nibbering, P. H. (1992). Effect of apocynin on the induction of ulcerative lesions in rat skin injected with tubercle bacteria. International Journal of Immunopharmacology, 14(6), 953-961.
    • (1992) International Journal of Immunopharmacology , vol.14 , Issue.6 , pp. 953-961
    • Hart, B.A.1    Elferink, J.G.2    Nibbering, P.H.3
  • 100
    • 0017134735 scopus 로고
    • The effects of diphenyleneiodonium on mitochondrial reactions. Relation of binding of diphenylene[125I]iodonium to mitochondria to the extent of inhibition of oxygen uptake
    • Gatley, S. J., & Sherratt, H. A. S. (1976). The effects of diphenyleneiodonium on mitochondrial reactions. Relation of binding of diphenylene[125I]iodonium to mitochondria to the extent of inhibition of oxygen uptake. Biochemical Journal, 158, 307-315.
    • (1976) Biochemical Journal , vol.158 , pp. 307-315
    • Gatley, S.J.1    Sherratt, H.A.S.2
  • 103
    • 79957890939 scopus 로고    scopus 로고
    • Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets
    • Drummond, G. R., Selemidis, S., Griendling, K. K., & Sobey, C. G. (2011). Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets. Nature Reviews. Drug Discovery, 10(6), 453-457.
    • (2011) Nature Reviews. Drug Discovery , vol.10 , Issue.6 , pp. 453-457
    • Drummond, G.R.1    Selemidis, S.2    Griendling, K.K.3    Sobey, C.G.4
  • 105
    • 84872220175 scopus 로고    scopus 로고
    • http://www.genkyotex.com/cdpdf/1320395578-GenKyoTex-Phase-I-Release-31- 10-11.pdf.
  • 106
    • 78149268561 scopus 로고    scopus 로고
    • First in class, potent, and orally bioavailable NADPH oxidase isoform 4 (Nox4) inhibitors for the treatment of idiopathic pulmonary fibrosis
    • Laleu, B., Gaggini, F., Orchard, M., Fioraso-Cartier, I., Cagnon, I., Houngninou-Molango, S., et al. (2010). First in class, potent, and orally bioavailable NADPH oxidase isoform 4 (Nox4) inhibitors for the treatment of idiopathic pulmonary fibrosis. Journal of Medicinal Chemistry, 53, 7715-7730.
    • (2010) Journal of Medicinal Chemistry , vol.53 , pp. 7715-7730
    • Laleu, B.1    Gaggini, F.2    Orchard, M.3    Fioraso-Cartier, I.4    Cagnon, I.5    Houngninou-Molango, S.6
  • 109
  • 110
    • 67649255876 scopus 로고    scopus 로고
    • A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish
    • Niethammer, P., Grabher, C., Look, A. T., & Mitchison, T. J. (2009). A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish. Nature, 459, 996-999.
    • (2009) Nature , vol.459 , pp. 996-999
    • Niethammer, P.1    Grabher, C.2    Look, A.T.3    Mitchison, T.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.