-
1
-
-
0027370108
-
The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
-
The Diabetes Control and Complications Trial Research Group: The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 329: 977-986, 1993
-
(1993)
N Engl J Med
, vol.329
, pp. 977-986
-
-
-
2
-
-
0032511583
-
Intensive blood glucose control with sulphonylurea or insulin compared with conventional treatment and the risk of complication in patients with type 2 diabetes
-
United Kingdom Prospective Diabetes Study 33: Intensive blood glucose control with sulphonylurea or insulin compared with conventional treatment and the risk of complication in patients with type 2 diabetes. Lancet 352: 837-853, 1998
-
(1998)
Lancet
, vol.352
, pp. 837-853
-
-
-
3
-
-
0036209325
-
Role of high glucose-induced nuclear factor-κB activation in monocyte chemoattractant protein-1 expression by mesangial cells
-
Ha H, Yu MR, Choi YJ, Kitamura M, Lee HB: Role of high glucose-induced nuclear factor-κB activation in monocyte chemoattractant protein-1 expression by mesangial cells. J Am Soc Nephrol 13: 894-902, 2002
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 894-902
-
-
Ha, H.1
Yu, M.R.2
Choi, Y.J.3
Kitamura, M.4
Lee, H.B.5
-
4
-
-
0033851574
-
Reactive oxygen species as glucose signaling molecules in mesangial cells cultured under high glucose
-
Ha H, Lee HB: Reactive oxygen species as glucose signaling molecules in mesangial cells cultured under high glucose. Kidney Int 58[Suppl 77]: S19-S25, 2000
-
(2000)
Kidney Int
, vol.58
, Issue.SUPPL. 77
-
-
Ha, H.1
Lee, H.B.2
-
5
-
-
0028218461
-
Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by autocrine activation of transforming growth factor-β
-
Ziyadeh FN, Sharma K, Ericksen M, Wolf G: Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by autocrine activation of transforming growth factor-β. J Clin Invest 93: 536-542, 1994
-
(1994)
J Clin Invest
, vol.93
, pp. 536-542
-
-
Ziyadeh, F.N.1
Sharma, K.2
Ericksen, M.3
Wolf, G.4
-
6
-
-
7844251526
-
Sequential effects of high glucose on mesangial cell transforming growth factor-β and fibronectin synthesis
-
Oh JH, Ha H, Yu MR, Lee HB: Sequential effects of high glucose on mesangial cell transforming growth factor-β and fibronectin synthesis. Kidney Int 54: 1872-1878, 1998
-
(1998)
Kidney Int
, vol.54
, pp. 1872-1878
-
-
Oh, J.H.1
Ha, H.2
Yu, M.R.3
Lee, H.B.4
-
7
-
-
0025369136
-
High glucose causes an increase in extracellular matrix proteins in cultured mesangial cells
-
Ayo SH, Radnik RA, Garoni JA, Glass WF II, Kreisberg JI: High glucose causes an increase in extracellular matrix proteins in cultured mesangial cells. Am J Pathol 136: 1339-1348, 1990
-
(1990)
Am J Pathol
, vol.136
, pp. 1339-1348
-
-
Ayo, S.H.1
Radnik, R.A.2
Garoni, J.A.3
Glass W.F. II4
Kreisberg, J.I.5
-
8
-
-
0035171881
-
Hydrogen peroxide increases extracellular matrix mRNA through TGF-beta in human mesangial cells
-
Iglesias-De La Cruz MC, Ruiz-Torres P, Alcami J, Diez-Marques L, Ortega-Velazquez R, Chen S, Rodriguez-Puyol M, Ziyadeh FN, Rodriguez-Puyol D: Hydrogen peroxide increases extracellular matrix mRNA through TGF-beta in human mesangial cells. Kidney Int 59: 87-95, 2001
-
(2001)
Kidney Int
, vol.59
, pp. 87-95
-
-
Iglesias-De La Cruz, M.C.1
Ruiz-Torres, P.2
Alcami, J.3
Diez-Marques, L.4
Ortega-Velazquez, R.5
Chen, S.6
Rodriguez-Puyol, M.7
Ziyadeh, F.N.8
Rodriguez-Puyol, D.9
-
9
-
-
0041360266
-
Role of reactive oxygen species in TGF-β1-induced epithelial-mesenchymal transition
-
Yang Y, Ha H, Lee HB: Role of reactive oxygen species in TGF-β1-induced epithelial-mesenchymal transition [Abstract]. Nephrol Dial Transplant 18[suppl 4]: 300, 2003
-
(2003)
Nephrol Dial Transplant
, vol.18
, Issue.SUPPL. 4
, pp. 300
-
-
Yang, Y.1
Ha, H.2
Lee, H.B.3
-
10
-
-
0030838053
-
Antioxidant inhibition of protein kinase C-signaled increase in transforming growth factor-beta in mesangial cells
-
Studer RK, Craven PA, Derubertis FR: Antioxidant inhibition of protein kinase C-signaled increase in transforming growth factor-beta in mesangial cells. Metabolism 46: 918-925, 1997
-
(1997)
Metabolism
, vol.46
, pp. 918-925
-
-
Studer, R.K.1
Craven, P.A.2
Derubertis, F.R.3
-
11
-
-
0030972189
-
Effects of rebamipide in a model of experimental diabetes and on the synthesis of transforming growth factor-beta and fibronectin, and lipid peroxidation induced by high glucose in cultured mesangial cells
-
Ha H, Lee SH, Kim KH: Effects of rebamipide in a model of experimental diabetes and on the synthesis of transforming growth factor-beta and fibronectin, and lipid peroxidation induced by high glucose in cultured mesangial cells. J Pharmacol Exp Ther 281: 1457-1462, 1997
-
(1997)
J Pharmacol Exp Ther
, vol.281
, pp. 1457-1462
-
-
Ha, H.1
Lee, S.H.2
Kim, K.H.3
-
12
-
-
4243462154
-
Mechanisms of reactive oxygen species generation in LLC-PK1 cells cultured under high glucose
-
Ha H, Yang Y, Lee HB: Mechanisms of reactive oxygen species generation in LLC-PK1 cells cultured under high glucose [Abstract]. J Am Soc Nephrol 13: 531A, 2002
-
(2002)
J Am Soc Nephrol
, vol.13
-
-
Ha, H.1
Yang, Y.2
Lee, H.B.3
-
13
-
-
0033765672
-
High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C-dependent activation of NAD(P)H oxidase in cultured vascular cells
-
Inoguchi T, Li P, Umeda F, Yu HY, Kakimoto M, Imamura M, Aoki T, Etoh T, Hashimoto T, Naruse M, Sano H, Utsumi H, Nawata H: High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C-dependent activation of NAD(P)H oxidase in cultured vascular cells. Diabetes 49: 1939-1945, 2000
-
(2000)
Diabetes
, vol.49
, pp. 1939-1945
-
-
Inoguchi, T.1
Li, P.2
Umeda, F.3
Yu, H.Y.4
Kakimoto, M.5
Imamura, M.6
Aoki, T.7
Etoh, T.8
Hashimoto, T.9
Naruse, M.10
Sano, H.11
Utsumi, H.12
Nawata, H.13
-
14
-
-
0037129803
-
Phosphorylation of p47phox sites by PKCα βII, δ, and η: Effect on binding to p 22phox and on NADPH oxidase activation
-
Fontayne A, Dang PM, Gougerot-Pocidalo MA, El-Benna J: Phosphorylation of p47phox sites by PKCα βII, δ, and η: Effect on binding to p22phox and on NADPH oxidase activation. Biochemistry 41: 7743-7750, 2002
-
(2002)
Biochemistry
, vol.41
, pp. 7743-7750
-
-
Fontayne, A.1
Dang, P.M.2
Gougerot-Pocidalo, M.A.3
El-Benna, J.4
-
15
-
-
0037123435
-
PKCη regulates TNF-α-induced activation of NADPH oxidase in endothelial cells
-
Frey RS, Rahman A, Kefer JC, Minshall RD, Malik AB: PKCη regulates TNF-α-induced activation of NADPH oxidase in endothelial cells. Circ Res 17: 1012-1019, 2002
-
(2002)
Circ Res
, vol.17
, pp. 1012-1019
-
-
Frey, R.S.1
Rahman, A.2
Kefer, J.C.3
Minshall, R.D.4
Malik, A.B.5
-
16
-
-
0034677947
-
NAD(P)H oxidase: Role in cardiovascular biology and disease
-
Griendling KK, Sorescu D, Ushio-Fukai M: NAD(P)H oxidase: Role in cardiovascular biology and disease. Circ Res 86: 494-501, 2000
-
(2000)
Circ Res
, vol.86
, pp. 494-501
-
-
Griendling, K.K.1
Sorescu, D.2
Ushio-Fukai, M.3
-
17
-
-
0037205457
-
Intracellular localization and preassembly of the NADPH oxidase complex in cultured endothelial cells
-
Li N-M, Shah AM: Intracellular localization and preassembly of the NADPH oxidase complex in cultured endothelial cells. J Biol Chem 277: 19952-19960, 2002
-
(2002)
J Biol Chem
, vol.277
, pp. 19952-19960
-
-
Li, N.-M.1
Shah, A.M.2
-
18
-
-
0034643340
-
Normalizing mitochondrial superoxide production blocks three different pathways of hyperglycemic damage
-
Nishikawa T, Edelstein D Du XL, Yamagishi S, Matsumura T, Kaneda Y, Yorek MA, Bee be D, Oates PJ, Hammes H-P, Giardino I, Brownlee M: Normalizing mitochondrial superoxide production blocks three different pathways of hyperglycemic damage. Nature 404: 787-790, 2000
-
(2000)
Nature
, vol.404
, pp. 787-790
-
-
Nishikawa, T.1
Edelstein, D.2
Du, X.L.3
Yamagishi, S.4
Matsumura, T.5
Kaneda, Y.6
Yorek, M.A.7
Bee be, D.8
Oates, P.J.9
Hammes, H.-P.10
Giardino, I.11
Brownlee, M.12
-
19
-
-
0033996388
-
AGEs induce oxidative stress and activate protein kinase C-βII in neonatal mesangial cells
-
Scivittaro V, Ganz MB, Weiss MF: AGEs induce oxidative stress and activate protein kinase C-βII in neonatal mesangial cells. Am J Physiol 278: F676-F683, 2000
-
(2000)
Am J Physiol
, vol.278
-
-
Scivittaro, V.1
Ganz, M.B.2
Weiss, M.F.3
-
20
-
-
0037246065
-
Advanced glycation end products inhibit de novo protein synthesis and induce TGF-β overexpression in proximal tubular cells
-
Yamagishi S-I, Inagaki Y, Okamoto T, Amano S, Koga K, Takeuchi M: Advanced glycation end products inhibit de novo protein synthesis and induce TGF-β overexpression in proximal tubular cells. Kidney Int 63: 464-473, 2003
-
(2003)
Kidney Int
, vol.63
, pp. 464-473
-
-
Yamagishi, S.-I.1
Inagaki, Y.2
Okamoto, T.3
Amano, S.4
Koga, K.5
Takeuchi, M.6
-
21
-
-
0034996659
-
Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE
-
Wautier MP, Chappey O, Corda S, Stern DM, Schmidt AM, Wautier JL: Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE. Am J Physiol 280: E685-E694, 2001
-
(2001)
Am J Physiol
, vol.280
-
-
Wautier, M.P.1
Chappey, O.2
Corda, S.3
Stern, D.M.4
Schmidt, A.M.5
Wautier, J.L.6
-
22
-
-
0036098848
-
Role of oxidative stress in advanced glycation end product-induced mesangial cell activation
-
Lal MA, Brismar H, Eklof AC, Aperia A: Role of oxidative stress in advanced glycation end product-induced mesangial cell activation. Kidney Int 61: 2006-2014, 2002
-
(2002)
Kidney Int
, vol.61
, pp. 2006-2014
-
-
Lal, M.A.1
Brismar, H.2
Eklof, A.C.3
Aperia, A.4
-
23
-
-
0031708389
-
Angiotensin II induces superoxide anion production by mesangial cells
-
Jaimes EA, Galceran JM, Raij L: Angiotensin II induces superoxide anion production by mesangial cells. Kidney Int 54: 775-784, 1998
-
(1998)
Kidney Int
, vol.54
, pp. 775-784
-
-
Jaimes, E.A.1
Galceran, J.M.2
Raij, L.3
-
24
-
-
0037032024
-
Angiotensin II stimulation of NAD(P)H oxidase activity: Upstream mediators
-
Seshiah PN, Weber DS, Rocic P, Valppu L, Tanuyama Y, Griendling KK: Angiotensin II stimulation of NAD(P)H oxidase activity: Upstream mediators. Circ Res 91: 406-413, 2002
-
(2002)
Circ Res
, vol.91
, pp. 406-413
-
-
Seshiah, P.N.1
Weber, D.S.2
Rocic, P.3
Valppu, L.4
Tanuyama, Y.5
Griendling, K.K.6
-
25
-
-
0034817425
-
Activation of protein kinase C-δ and C-ε by oxidative stress in early diabetic rat kidney
-
Ha H, Yu MR, Choi YJ, Lee HB: Activation of protein kinase C-δ and C-ε by oxidative stress in early diabetic rat kidney. Am J Kidney Dis 38[Suppl 1]: S204-S207, 2001
-
(2001)
Am J Kidney Dis
, vol.38
, Issue.SUPPL. 1
-
-
Ha, H.1
Yu, M.R.2
Choi, Y.J.3
Lee, H.B.4
-
26
-
-
0033930127
-
Small heat shock protein alteration provide a mechanism to reduce mesangial cell contractility in diabetes and oxidative stress
-
Dunlop ME, Muggli EE: Small heat shock protein alteration provide a mechanism to reduce mesangial cell contractility in diabetes and oxidative stress. Kidney Int 57: 464-475, 2000
-
(2000)
Kidney Int
, vol.57
, pp. 464-475
-
-
Dunlop, M.E.1
Muggli, E.E.2
-
27
-
-
0035720552
-
Chronic exposure of human mesangial cells to high glucose environment activates the p38 MAPK pathway
-
Wilmer WA, Dixon CL, Herbert C: Chronic exposure of human mesangial cells to high glucose environment activates the p38 MAPK pathway. Kidney Int 60: 858-871, 2001
-
(2001)
Kidney Int
, vol.60
, pp. 858-871
-
-
Wilmer, W.A.1
Dixon, C.L.2
Herbert, C.3
-
28
-
-
0037369950
-
Delayed treatment with lithospermate B attenuates experimental diabetic renal injury
-
Lee GT, Ha H, Jung M, Li HR, Hong SW, Cha BS, Lee HC, Cho DH: Delayed treatment with lithospermate B attenuates experimental diabetic renal injury. J Am Soc Nephrol 14: 709-720, 2003
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 709-720
-
-
Lee, G.T.1
Ha, H.2
Jung, M.3
Li, H.R.4
Hong, S.W.5
Cha, B.S.6
Lee, H.C.7
Cho, D.H.8
-
29
-
-
4243797428
-
Reversal of extracellular signal-regulated kinase activation by lithospermate B in experimental diabetes
-
Ha H, Yu MR, Lee GT, Lee HC, Lee HB: Reversal of extracellular signal-regulated kinase activation by lithospermate B in experimental diabetes [Abstract]. J Am Soc Nephrol 12: 836A, 2001
-
(2001)
J Am Soc Nephrol
, vol.12
-
-
Ha, H.1
Yu, M.R.2
Lee, G.T.3
Lee, H.C.4
Lee, H.B.5
-
30
-
-
0036894194
-
Inhibition of the JAK/STAT signaling pathway prevents the high glucose-induced increase in TGF-β and fibronectin synthesis in mesangial cells
-
Wang X, Shaw S, Amiri F, Eaton DC, Marrero MB: Inhibition of the JAK/STAT signaling pathway prevents the high glucose-induced increase in TGF-β and fibronectin synthesis in mesangial cells. Diabetes 51: 3505-3509, 2002
-
(2002)
Diabetes
, vol.51
, pp. 3505-3509
-
-
Wang, X.1
Shaw, S.2
Amiri, F.3
Eaton, D.C.4
Marrero, M.B.5
-
32
-
-
0034533082
-
Reactive oxygen species in cell signaling
-
Thannickal VJ, Fanburg BL: Reactive oxygen species in cell signaling. Am J Physiol 279: L1005-L1028, 2000
-
(2000)
Am J Physiol
, vol.279
-
-
Thannickal, V.J.1
Fanburg, B.L.2
-
33
-
-
0037213082
-
Mycophenolate mofetil prevents the development of glomerular injury in experimental diabetes
-
Utimura R, Fujihara CK, Mattar AL, Malheiros DMAC, de Lourdes Noronha I, Zatz R: Mycophenolate mofetil prevents the development of glomerular injury in experimental diabetes. Kidney Int 63: 209-216, 2003
-
(2003)
Kidney Int
, vol.63
, pp. 209-216
-
-
Utimura, R.1
Fujihara, C.K.2
Mattar, A.L.3
Malheiros, D.M.A.C.4
De Lourdes Noronha, I.5
Zatz, R.6
-
34
-
-
0033806619
-
Upregulation of monocyte chemoattractant protein-1 in tubulointerstitial lesions of human diabetic nephropathy
-
Wada T, Furuichi K, Sakai N, Iwata Y, Yoshimoto K, Shimizu M, Takeda SI, Takasawa K, Yoshimura M, Kida H, Kobayashi KI, Mukaida N, Naito T, Matsushima K, Yokoyama H: Upregulation of monocyte chemoattractant protein-1 in tubulointerstitial lesions of human diabetic nephropathy. Kidney Int 58: 1492-1499, 2000
-
(2000)
Kidney Int
, vol.58
, pp. 1492-1499
-
-
Wada, T.1
Furuichi, K.2
Sakai, N.3
Iwata, Y.4
Yoshimoto, K.5
Shimizu, M.6
Takeda, S.I.7
Takasawa, K.8
Yoshimura, M.9
Kida, H.10
Kobayashi, K.I.11
Mukaida, N.12
Naito, T.13
Matsushima, K.14
Yokoyama, H.15
-
35
-
-
0033760187
-
AP-1 proteins mediate hyperglycemia-induced activation of the human TGF-β1 promoter in mesangial cells
-
Weigert C, Sauer U, Brodbeck K, Pfilffer A, Haering HU, Schleicher ED: AP-1 proteins mediate hyperglycemia-induced activation of the human TGF-β1 promoter in mesangial cells. J Am Soc Nephrol 11: 2007-2016, 2000
-
(2000)
J Am Soc Nephrol
, vol.11
, pp. 2007-2016
-
-
Weigert, C.1
Sauer, U.2
Brodbeck, K.3
Pfilffer, A.4
Haering, H.U.5
Schleicher, E.D.6
-
36
-
-
0034710891
-
Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation
-
Du XL, Edelstein D, Rossetti L, Fantus IG, Goldberg H, Ziyadeh F, Wu J, Brownlee M: Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation. Proc Natl Acad Sci U S A 97: 12222-12226, 2000
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 12222-12226
-
-
Du, X.L.1
Edelstein, D.2
Rossetti, L.3
Fantus, I.G.4
Goldberg, H.5
Ziyadeh, F.6
Wu, J.7
Brownlee, M.8
-
37
-
-
0034608948
-
Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal anti-transforming growth factor-β antibody in db/db mice
-
Ziyadeh FN, Hoffman BB, Iglesias-De La Cruz MC, Han DC, Hong SW, Isono M, Chen S, Mcwan T, Sharma K: Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal anti-transforming growth factor-β antibody in db/db mice. Proc Natl Acad Sci U S A 97: 8015-8020, 2000
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 8015-8020
-
-
Ziyadeh, F.N.1
Hoffman, B.B.2
Iglesias-De La Cruz, M.C.3
Han, D.C.4
Hong, S.W.5
Isono, M.6
Chen, S.7
Mcwan, T.8
Sharma, K.9
-
38
-
-
0035661067
-
Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE)
-
Oldfield MD, Bach LS, Forbes JM, Nikolic-Pateerson D, McRobert A, Thallas V, Atkins RC, Osicka T, Jerums G, Cooper ME: Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE). J Clin Invest 108: 1853-1863, 2001
-
(2001)
J Clin Invest
, vol.108
, pp. 1853-1863
-
-
Oldfield, M.D.1
Bach, L.S.2
Forbes, J.M.3
Nikolic-Pateerson, D.4
McRobert, A.5
Thallas, V.6
Atkins, R.C.7
Osicka, T.8
Jerums, G.9
Cooper, M.E.10
-
39
-
-
0032983588
-
Transforming growth factor-β is a potent inhibitor of extracellular matrix degradation by cultured human mesangial cells
-
Baricos WH, Cortez SL, Deboisblanc M, Xin S: Transforming growth factor-β is a potent inhibitor of extracellular matrix degradation by cultured human mesangial cells. J Am Soc Nephrol 10: 790-795, 1999
-
(1999)
J Am Soc Nephrol
, vol.10
, pp. 790-795
-
-
Baricos, W.H.1
Cortez, S.L.2
Deboisblanc, M.3
Xin, S.4
-
40
-
-
4243664187
-
Reactive oxygen species mediate upregulation of plasminogen activator inhibitor-1 secretion by mesangial cells cultured under high glucose
-
Ha H, Seo J, Lee EA, Kim YS, Lee HB: Reactive oxygen species mediate upregulation of plasminogen activator inhibitor-1 secretion by mesangial cells cultured under high glucose [Abstract]. J Am Soc Nephrol 12: 836A, 2001
-
(2001)
J Am Soc Nephrol
, vol.12
-
-
Ha, H.1
Seo, J.2
Lee, E.A.3
Kim, Y.S.4
Lee, H.B.5
-
41
-
-
0032923362
-
Melatonin and taurine reduce early glomerulopathy in diabetic rats
-
Ha H, Yu MR, Kim KH: Melatonin and taurine reduce early glomerulopathy in diabetic rats. Free Radic Biol Med 26: 944-950, 1999
-
(1999)
Free Radic Biol Med
, vol.26
, pp. 944-950
-
-
Ha, H.1
Yu, M.R.2
Kim, K.H.3
|