Potential role of the NADPH oxidase NOX1 in the pathogenesis of 5-fluorouracil-induced intestinal mucositis in mice

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 302, Issue 10, 2012, Pages

  Yasuda, Masashi ^a   Kato, Shinichi ^a   Yamanaka, Naoki ^a   Iimori, Maho ^a   Utsumi, Daichi ^a   Kitahara, Yumeno ^a   Iwata, Kazumi ^b   Matsuno, Kuniharu ^b   Amagase, Kikuko ^a   Yabe Nishimura, Chihiro ^b   Takeuchi, Koji ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Apoptosis; Caspase; Inflammatory cytokines; Nox1 knock out mice; Reactive oxygen species

Indexed keywords

CASPASE 3; CASPASE 8; FLUOROURACIL; INTERLEUKIN 1BETA; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BODY WEIGHT; CELL DAMAGE; CELL PROLIFERATION; CONTROLLED STUDY; CRYPT CELL; DIARRHEA; DIGESTIVE SYSTEM DISEASE; DISEASE SEVERITY; ENZYME ACTIVATION; INTESTINE CRYPT; INTESTINE VILLUS; MOUSE; MUCOSA INFLAMMATION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; WILD TYPE;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CASPASE 3; CYTOKINES; FLUOROURACIL; INTESTINAL MUCOSA; MICE; MICE, KNOCKOUT; MUCOSITIS; NADH, NADPH OXIDOREDUCTASES; REACTIVE OXYGEN SPECIES; SEVERITY OF ILLNESS INDEX; UP-REGULATION; WEIGHT LOSS;

EID: 84861173445     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00535.2011     Document Type: Article

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