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Volumn 20, Issue 13, 2000, Pages 4745-4753

Bcl-2 retards cell cycle entry through p27(Kip1), pRB relative p130, and altered E2F regulation

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN BCL 2; PROTEIN P130; PROTEIN P27; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F;

EID: 0034082459     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.13.4745-4753.2000     Document Type: Article
Times cited : (129)

References (51)
  • 1
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Arbiters of cell survival
    • Adams, J. M., and S. Cory. 1998. The Bcl-2 protein family: arbiters of cell survival. Science 281:1322-1326.
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 2
    • 0029666094 scopus 로고    scopus 로고
    • Repression of p27kip1 synthesis by platelet-derived growth factor in BALB/c 3T3 cells
    • Agrawal, D., P. Hauser, F. McPherson, F. Dong, A. Garcia, and W. J. Pledger. 1996. Repression of p27kip1 synthesis by platelet-derived growth factor in BALB/c 3T3 cells. Mol. Cell. Biol. 16:4327-4336.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4327-4336
    • Agrawal, D.1    Hauser, P.2    McPherson, F.3    Dong, F.4    Garcia, A.5    Pledger, W.J.6
  • 4
    • 0030449990 scopus 로고    scopus 로고
    • Baxα perturbs T cell development and affects cell cycle entry of T cells
    • Brady, H. J. M., G. Gil-Gómez, J. Kirberg, and A. J. M. Berns. 1996. Baxα perturbs T cell development and affects cell cycle entry of T cells. EMBO J. 15:6991-7001.
    • (1996) EMBO J. , vol.15 , pp. 6991-7001
    • Brady, H.J.M.1    Gil-Gómez, G.2    Kirberg, J.3    Berns, A.J.M.4
  • 5
    • 0031865232 scopus 로고    scopus 로고
    • Dual cyclin-binding domains are required for p107 to function as a kinase inhibitor
    • Castaño, E., Y. Kleyner, and B. D. Dynlacht. 1998. Dual cyclin-binding domains are required for p107 to function as a kinase inhibitor. Mol. Cell. Biol. 18:5380-5391.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 5380-5391
    • Castaño, E.1    Kleyner, Y.2    Dynlacht, B.D.3
  • 10
    • 0032146274 scopus 로고    scopus 로고
    • The regulation of E2F by pRB-family proteins
    • Dyson, N. 1998. The regulation of E2F by pRB-family proteins. Genes Dev. 12:2245-2262.
    • (1998) Genes Dev. , vol.12 , pp. 2245-2262
    • Dyson, N.1
  • 11
    • 0032575705 scopus 로고    scopus 로고
    • A matter of life and cell death
    • Evan, G., and T. Littlewood. 1998. A matter of life and cell death. Science 281:1317-1321.
    • (1998) Science , vol.281 , pp. 1317-1321
    • Evan, G.1    Littlewood, T.2
  • 13
    • 0033547366 scopus 로고    scopus 로고
    • Loss of anti-mitotic effects of Bcl-2 with retention of anti-apoptotic activity during tumor progression in a mouse model
    • Furth, P. A., U. Bar-Peled, M. Li, A. Lewis, R. Laucirica, R. Jäger, H. Weiher, and R. G. Russell. 1999. Loss of anti-mitotic effects of Bcl-2 with retention of anti-apoptotic activity during tumor progression in a mouse model. Oncogene 18:6589-6596.
    • (1999) Oncogene , vol.18 , pp. 6589-6596
    • Furth, P.A.1    Bar-Peled, U.2    Li, M.3    Lewis, A.4    Laucirica, R.5    Jäger, R.6    Weiher, H.7    Russell, R.G.8
  • 14
    • 0033580436 scopus 로고    scopus 로고
    • Transcriptional repression of the E2F-1 gene by interferon-α is mediated through induction of E2F-4/pRB and E2F-4/p130 complexes
    • Furukawa, Y., S. Iwase, J. Kikuchi, M. Nakamura, H. Yamada, and M. Matsuda. 1999. Transcriptional repression of the E2F-1 gene by interferon-α is mediated through induction of E2F-4/pRB and E2F-4/p130 complexes. Oncogene 18:2003-2014.
    • (1999) Oncogene , vol.18 , pp. 2003-2014
    • Furukawa, Y.1    Iwase, S.2    Kikuchi, J.3    Nakamura, M.4    Yamada, H.5    Matsuda, M.6
  • 16
    • 0029670477 scopus 로고    scopus 로고
    • Translational control of p27Kip1 accumulation during the cell cycle
    • Hengst, L., and S. I. Reed. 1996. Translational control of p27Kip1 accumulation during the cell cycle. Science 271:1861-1864.
    • (1996) Science , vol.271 , pp. 1861-1864
    • Hengst, L.1    Reed, S.I.2
  • 17
    • 0030794452 scopus 로고    scopus 로고
    • The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry
    • Huang, D. C. S., L. A. O'Reilly, A. Strasser, and S. Cory. 1997. The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry. EMBO J. 16:4628-4638.
    • (1997) EMBO J. , vol.16 , pp. 4628-4638
    • Huang, D.C.S.1    O'Reilly, L.A.2    Strasser, A.3    Cory, S.4
  • 18
    • 15444353328 scopus 로고    scopus 로고
    • pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes
    • Hurford, R. K., Jr., D. Cobrinik, M.-H. Lee, and N. Dyson. 1997. pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes. Genes Dev. 11:1447-1463.
    • (1997) Genes Dev. , vol.11 , pp. 1447-1463
    • Hurford R.K., Jr.1    Cobrinik, D.2    Lee, M.-H.3    Dyson, N.4
  • 19
    • 0032933352 scopus 로고    scopus 로고
    • E2F and histone deacetylase mediate transforming growth factor beta repression of cdc25A during keratinocyte cell cycle arrest
    • Iavarone, A., and J. Massague. 1999. E2F and histone deacetylase mediate transforming growth factor beta repression of cdc25A during keratinocyte cell cycle arrest. Mol. Cell. Biol. 19:916-922.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 916-922
    • Iavarone, A.1    Massague, J.2
  • 20
    • 0029868367 scopus 로고    scopus 로고
    • A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation
    • Ikeda, M., L. Jakoi, and J. R. Nevins. 1996. A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation. Proc. Natl. Acad. Sci. USA 93:3215-3220.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 3215-3220
    • Ikeda, M.1    Jakoi, L.2    Nevins, J.R.3
  • 21
    • 0028791305 scopus 로고
    • Regulation of E2F-1 gene expression by p130 (Rb2) and D-type cyclin kinase activity
    • Johnson, D. G. 1995. Regulation of E2F-1 gene expression by p130 (Rb2) and D-type cyclin kinase activity. Oncogene 11:1685-1692.
    • (1995) Oncogene , vol.11 , pp. 1685-1692
    • Johnson, D.G.1
  • 24
    • 0033118927 scopus 로고    scopus 로고
    • Timing of cyclin E gene expression depends on the regulated association of a bipartite repressor element with a novel E2F complex
    • Le Cam, L., J. Polanowska, E. Fabbrizio, M. Olivier, A. Philips, E. Ng Eaton, M. Classon, Y. Geng, and C. Sardet. 1999. Timing of cyclin E gene expression depends on the regulated association of a bipartite repressor element with a novel E2F complex. EMBO J. 18:1878-1890.
    • (1999) EMBO J. , vol.18 , pp. 1878-1890
    • Le Cam, L.1    Polanowska, J.2    Fabbrizio, E.3    Olivier, M.4    Philips, A.5    Ng Eaton, E.6    Classon, M.7    Geng, Y.8    Sardet, C.9
  • 26
    • 0032528027 scopus 로고    scopus 로고
    • E2F3 activity is regulated during the cell cycle and is required for the induction of S phase
    • Leone, G., J. DeGregori, Z. Yan, L. Jakoi, S. Ishida, R. S. Williams, and J. R. Nevins. 1998. E2F3 activity is regulated during the cell cycle and is required for the induction of S phase. Genes Dev. 12:2120-2130.
    • (1998) Genes Dev. , vol.12 , pp. 2120-2130
    • Leone, G.1    DeGregori, J.2    Yan, Z.3    Jakoi, L.4    Ishida, S.5    Williams, R.S.6    Nevins, J.R.7
  • 28
    • 0033136278 scopus 로고    scopus 로고
    • Bcl-2-induced changes in E2F regulatory complexes reveal the potential for integrated cell cycle and cell death functions
    • Lind, E. F., J. Wayne, Q.-Z. Wang, T. Staeva, A. Stolzer, and H. T. Petrie. 1999. Bcl-2-induced changes in E2F regulatory complexes reveal the potential for integrated cell cycle and cell death functions. J. Immunol. 162:5374-5379.
    • (1999) J. Immunol. , vol.162 , pp. 5374-5379
    • Lind, E.F.1    Wayne, J.2    Wang, Q.-Z.3    Staeva, T.4    Stolzer, A.5    Petrie, H.T.6
  • 29
    • 0029843941 scopus 로고    scopus 로고
    • Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation
    • Linette, G. P., Y. Li, K. Roth, and S. J. Korsmeyer. 1996. Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation. Proc. Natl. Acad. Sci. USA 93:9545-9552.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 9545-9552
    • Linette, G.P.1    Li, Y.2    Roth, K.3    Korsmeyer, S.J.4
  • 30
    • 0029938724 scopus 로고    scopus 로고
    • Regulation of cell division cycle progression by bcl-2 expression: A potential mechanism for inhibition of programmed cell death
    • Mazel, S., D. Burtrum, and H. T. Petrie. 1996. Regulation of cell division cycle progression by bcl-2 expression: a potential mechanism for inhibition of programmed cell death. J. Exp. Med. 183:2219-2226.
    • (1996) J. Exp. Med. , vol.183 , pp. 2219-2226
    • Mazel, S.1    Burtrum, D.2    Petrie, H.T.3
  • 31
    • 15144357686 scopus 로고    scopus 로고
    • Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest
    • Millard, S. S., J. S. Yan, H. Nguyen, M. Pagano, H. Kiyokawa, and A. Koff. 1997. Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest. J. Biol. Chem. 272:7093-7098.
    • (1997) J. Biol. Chem. , vol.272 , pp. 7093-7098
    • Millard, S.S.1    Yan, J.S.2    Nguyen, H.3    Pagano, M.4    Kiyokawa, H.5    Koff, A.6
  • 32
    • 0029978325 scopus 로고    scopus 로고
    • E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry
    • Moberg, K., M. A. Starz, and J. A. Lees. 1996. E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry. Mol. Cell. Biol. 16:1436-1449.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1436-1449
    • Moberg, K.1    Starz, M.A.2    Lees, J.A.3
  • 33
    • 0033547304 scopus 로고    scopus 로고
    • Bcl-2 expression delays mammary tumor development in dimethylbenz(a)anthracene-treated transgenic mice
    • Murphy, K. L., F. S. Kittrell, J. P. Gay, R. Jäger, D. Medina, and J. M. Rosen. 1999. Bcl-2 expression delays mammary tumor development in dimethylbenz(a)anthracene-treated transgenic mice. Oncogene 18:6597-6604.
    • (1999) Oncogene , vol.18 , pp. 6597-6604
    • Murphy, K.L.1    Kittrell, F.S.2    Gay, J.P.3    Jäger, R.4    Medina, D.5    Rosen, J.M.6
  • 34
    • 0031815596 scopus 로고    scopus 로고
    • Toward an understanding of the functional complexity of the E2F and retinoblastoma families
    • Nevins, J. R. 1998. Toward an understanding of the functional complexity of the E2F and retinoblastoma families. Cell Growth Differ. 9:585-593.
    • (1998) Cell Growth Differ. , vol.9 , pp. 585-593
    • Nevins, J.R.1
  • 35
    • 0030476922 scopus 로고    scopus 로고
    • The cell death inhibitor Bcl-2 and its homologues influence control of cell cycle entry
    • O'Reilly, L. A., D. C. S. Huang, and A. Strasser. 1996. The cell death inhibitor Bcl-2 and its homologues influence control of cell cycle entry. EMBO J. 15:6979-6990.
    • (1996) EMBO J. , vol.15 , pp. 6979-6990
    • O'Reilly, L.A.1    Huang, D.C.S.2    Strasser, A.3
  • 38
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr, C. J. 1996. Cancer cell cycles. Science 274:1672-1677.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 39
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: Positive and negative regulators of G1-phase progression
    • Sherr, C. J., and J. M. Roberts. 1999. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 13:1501-1512.
    • (1999) Genes Dev. , vol.13 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 40
    • 0030813562 scopus 로고    scopus 로고
    • p27Kip1 induces an accumulation of the repressor complexes of E2F and inhibits expression of the E2F-regulated genes
    • Shiyanov, P., S. Hayes, N. Chen, D. G. Pestov, L. F. Lau, and P. Raychaudhuri. 1997. p27Kip1 induces an accumulation of the repressor complexes of E2F and inhibits expression of the E2F-regulated genes. Mol. Biol. Cell 8:1815-1827.
    • (1997) Mol. Biol. Cell , vol.8 , pp. 1815-1827
    • Shiyanov, P.1    Hayes, S.2    Chen, N.3    Pestov, D.G.4    Lau, L.F.5    Raychaudhuri, P.6
  • 41
    • 0031815206 scopus 로고    scopus 로고
    • Distinct mechanisms control the accumulation of the Rb-related p107 and p130 proteins during cell growth
    • Smith, E. J., G. Leone, and J. R. Nevins. 1998. Distinct mechanisms control the accumulation of the Rb-related p107 and p130 proteins during cell growth. Cell Growth Differ. 9:297-303.
    • (1998) Cell Growth Differ. , vol.9 , pp. 297-303
    • Smith, E.J.1    Leone, G.2    Nevins, J.R.3
  • 42
    • 0025786164 scopus 로고
    • Bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship
    • Strasser, A., A. W. Harris, and S. Cory. 1991. Bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship. Cell 67:889-899.
    • (1991) Cell , vol.67 , pp. 889-899
    • Strasser, A.1    Harris, A.W.2    Cory, S.3
  • 43
    • 0031975921 scopus 로고    scopus 로고
    • E2f-1 and E2f-3 are functionally distinct in their ability to promote myeloid cell cycle progression and block granulocyte differentiation
    • Strom, D. K., J. L. Cleveland, S. Chellappan, J. Nip, and S. W. Hiebert. 1998. E2f-1 and E2f-3 are functionally distinct in their ability to promote myeloid cell cycle progression and block granulocyte differentiation. Cell Growth Differ. 9:59-69.
    • (1998) Cell Growth Differ. , vol.9 , pp. 59-69
    • Strom, D.K.1    Cleveland, J.L.2    Chellappan, S.3    Nip, J.4    Hiebert, S.W.5
  • 45
    • 0029895458 scopus 로고    scopus 로고
    • Deletion of a nonconserved region of Bcl-2 confers a novel gain of function: Suppression of apoptosis with concomitant cell proliferation
    • Uhlmann, E. J., C. D'Sa-Eipper, T. Subramanian, A. J. Wagner, N. Hay, and G. Chinnadurai. 1996. Deletion of a nonconserved region of Bcl-2 confers a novel gain of function: suppression of apoptosis with concomitant cell proliferation. Cancer Res. 56:2506-2509.
    • (1996) Cancer Res. , vol.56 , pp. 2506-2509
    • Uhlmann, E.J.1    D'Sa-Eipper, C.2    Subramanian, T.3    Wagner, A.J.4    Hay, N.5    Chinnadurai, G.6
  • 46
    • 0029805403 scopus 로고    scopus 로고
    • Bcl-2 has a cell cycle inhibitory function separable from its enhancement of cell survival
    • Vairo, G., K. M. Innes, and J. M. Adams. 1996. Bcl-2 has a cell cycle inhibitory function separable from its enhancement of cell survival. Oncogene 13:1511-1519.
    • (1996) Oncogene , vol.13 , pp. 1511-1519
    • Vairo, G.1    Innes, K.M.2    Adams, J.M.3
  • 47
    • 0028902381 scopus 로고
    • Functional interaction between E2F-4 and p130: Evidence for distinct mechanisms underlying growth suppression by different retinoblastoma protein family members
    • Vairo, G., D. M. Livingston, and D. Ginsberg. 1995. Functional interaction between E2F-4 and p130: evidence for distinct mechanisms underlying growth suppression by different retinoblastoma protein family members. Genes Dev. 9:869-881.
    • (1995) Genes Dev. , vol.9 , pp. 869-881
    • Vairo, G.1    Livingston, D.M.2    Ginsberg, D.3
  • 49
    • 0031816342 scopus 로고    scopus 로고
    • Inhibition of cyclin D1 kinase activity is associated with E2F-mediated inhibition of cyclin D1 promoter activity through E2F and Sp1
    • Watanabe, G., C. Albanese, R. J. Lee, A. Reutens, G. Vairo, B. Henglein, and R. G. Pestell. 1998. Inhibition of cyclin D1 kinase activity is associated with E2F-mediated inhibition of cyclin D1 promoter activity through E2F and Sp1. Mol. Cell. Biol. 18:3212-3222.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 3212-3222
    • Watanabe, G.1    Albanese, C.2    Lee, R.J.3    Reutens, A.4    Vairo, G.5    Henglein, B.6    Pestell, R.G.7
  • 50
    • 0029091312 scopus 로고
    • Role of pRb-related proteins in simian virus 40 large-T-antigen-mediated transformation
    • Zalvide, J., and J. A. DeCaprio. 1995. Role of pRb-related proteins in simian virus 40 large-T-antigen-mediated transformation. Mol. Cell. Biol. 15:5800-5810.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 5800-5810
    • Zalvide, J.1    DeCaprio, J.A.2
  • 51
    • 0029054133 scopus 로고
    • Differential roles of two tandem E2F sites in repression of the human p107 promoter by retinoblastoma and p107 proteins
    • Zhu, L., L. Zhu, E. Xie, and L. S. Chang. 1995. Differential roles of two tandem E2F sites in repression of the human p107 promoter by retinoblastoma and p107 proteins. Mol. Cell. Biol. 15:3552-3562.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3552-3562
    • Zhu, L.1    Zhu, L.2    Xie, E.3    Chang, L.S.4


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