Human cells enter mitosis with damaged DNA after treatment with pharmacological concentrations of genotoxic agents

Biochemical Journal

Volumn 446, Issue 3, 2012, Pages 373-381

  Kubara, Philip M ^a   Kernéis Golsteyn, Sophie ^a   Studény, Aurélie ^b   Lanser, Brittany B ^a   Meijer, Laurent ^c   Golsteyn, Roy M ^a  

^a UNIVERSITY OF LETHBRIDGE   (Canada)

^b INSTITUT DE RECHERCHES SERVIER   (France)

^c STATION BIOLOGIQUE   (France)

Author keywords

Camptothecin; Checkpoint adaptation; Checkpoint kinase 1 (Chk1); Cyclin dependent kinase 1 (Cdk1); Mitosis; Mitotic catastrophe

Indexed keywords

CHECKPOINT KINASE 1; CYCLIN DEPENDENT KINASE 1; POLO LIKE KINASE 1;

ARTICLE; CELL CYCLE; DNA DAMAGE; GENOTOXICITY; HUMAN; HUMAN CELL; MITOSIS; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

CDC2 PROTEIN KINASE; CELL CYCLE; CELL CYCLE PROTEINS; DNA; DNA DAMAGE; GENOME; HT29 CELLS; HUMANS; MITOSIS; MUTAGENS; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS;

EID: 84865609599     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20120385     Document Type: Article

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