Bone repair: New developments in growth factor delivery systems and their mathematical modeling

Journal of Controlled Release

Volumn 162, Issue 3, 2012, Pages 502-520

  Lauzon, Marc Antoine ^a   Bergeron, Éric ^b   Marcos, Bernard ^a   Faucheux, Nathalie ^a  

^a UNIVERSITÉ DE SHERBROOKE   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

BMPs; Collagen; Cytokines; Mass transport; Peptides; Scaffold

Indexed keywords

AGING POPULATION; BIOLOGICAL EFFECTS; BMPS; BONE DEFECT; BONE GRAFT; BONE HEALING; BONE MORPHOGENETIC PROTEINS; BONE REPAIR; CYTOKINES; DELIVERY SYSTEMS; DRUG DELIVERY SYSTEM; FOOD AND DRUG ADMINISTRATION; GROWTH FACTOR; GROWTH FACTOR DELIVERY; NEW STUDY; PHYSIOLOGICAL ENVIRONMENT; SYNTHETIC BIOMATERIALS; TRANSPORT PHENOMENA;

BIOLOGICAL MATERIALS; COLLAGEN; DRUG DELIVERY; HYDROGELS; MASS TRANSFER; MATHEMATICAL MODELS; PEPTIDES; SCAFFOLDS;

BONE;

ANGIOPOIETIN; BIOMATERIAL; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 14; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 9; CALCIUM PHOSPHATE; CALCIUM PHOSPHATE DIBASIC; CHITOSAN; COLLAGEN TYPE 1; COPOLYMER; CYTOKINE; FIBROBLAST GROWTH FACTOR; GLYCOSAMINOGLYCAN; GROWTH FACTOR; HYALURONIC ACID; HYDROXYAPATITE; INORGANIC COMPOUND; MICROSPHERE; ORGANIC COMPOUND; OSTEOGENIC PROTEIN 1; PLATELET DERIVED GROWTH FACTOR; POLYGLACTIN; POLYMER; SILK FIBROIN; SOMATOMEDIN; TISSUE SCAFFOLD; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULOTROPIN;

ADSORPTION; ANGIOGENESIS; BINDING AFFINITY; BIOCHEMICAL COMPOSITION; BIOCOMPATIBILITY; BONE CONDUCTION; BONE GRAFT; BONE MATRIX; BONE REMODELING; CARTILAGE; CELL DIFFERENTIATION; CHONDROGENESIS; CYTOKINE RELEASE; DIFFUSION; DRUG DELIVERY SYSTEM; DRUG POTENCY; DRUG TRANSPORT; ENCAPSULATION; ENCHONDRAL OSSIFICATION; FOOD AND DRUG ADMINISTRATION; FRACTURE HEALING; HUMAN; HYDROGEL; INFLAMMATION; MATHEMATICAL MODEL; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCLAST; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; SUSTAINED DRUG RELEASE; WETTABILITY;

ANIMALS; BONE REGENERATION; DRUG DELIVERY SYSTEMS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MODELS, THEORETICAL;

EID: 84865585993     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.07.041     Document Type: Review

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