Spatiotemporal delivery of bone morphogenetic protein enhances functional repair of segmental bone defects

Bone

Volumn 49, Issue 3, 2011, Pages 485-492

  Kolambkar, Yash M ^a   Boerckel, Joel D ^b   Dupont, Kenneth M ^b   Bajin, Mehmet ^a   Huebsch, Nathaniel ^c   Mooney, David J ^c   Hutmacher, Dietmar W ^d   Guldberg, Robert E ^b  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^c HARVARD UNIVERSITY   (United States)

^d QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

Author keywords

Alginate; Bone morphogenetic protein; Bone regeneration; Collagen; Drug delivery; Nanofiber mesh

Indexed keywords

ALGINIC ACID; COLLAGEN SPONGE; NANOFIBER; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BONE DEFECT; BONE MATRIX; BONE MINERALIZATION; BONE REGENERATION; BONE REMODELING; CONTROLLED STUDY; DISEASE MODEL; DRUG DELIVERY SYSTEM; DRUG EFFICACY; FEMALE; HYDROGEL; INTERMETHOD COMPARISON; NONHUMAN; OSSIFICATION; RAT;

ANIMALS; BIOMECHANICS; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEINS; BONE REGENERATION; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FEMALE; FEMUR; HUMANS; NANOFIBERS; OSTEOGENESIS; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; STRESS, MECHANICAL; TRANSFORMING GROWTH FACTOR BETA; X-RAY MICROTOMOGRAPHY;

EID: 79960581511     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2011.05.010     Document Type: Article

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