Sequential release kinetics of two (gentamicin and BMP-2) or three (gentamicin, IGF-I and BMP-2) substances from a one-component polymeric coating on implants

Journal of Controlled Release

Volumn 156, Issue 1, 2011, Pages 37-45

  Strobel, Catrin ^a   Bormann, Nicole ^a   Kadow Romacker, Anke ^a   Schmidmaier, Gerhard ^b   Wildemann, Britt ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

Antibiotic; Bioactivity; Drug release; Growth factors; Polymer coating

Indexed keywords

ANTIBIOTICS; BIOACTIVITY; BONE; CELL PROLIFERATION; METABOLISM; PHOSPHATASES; PLASTIC COATINGS; POLYMERIC IMPLANTS; TAPE COATINGS; TARGETED DRUG DELIVERY;

ALKALINE PHOSPHATASE ACTIVITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; GROWTH FACTOR; POLY (D ,L-LACTIDE); POLYMER COATING; POLYMER CONCENTRATIONS; PRIMARY OSTEOBLASTS;

CONTROLLED DRUG DELIVERY;

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; GENTAMICIN; POLYLACTIDE; SOMATOMEDIN C;

ANIMAL CELL; ANTIMICROBIAL ACTIVITY; ARTICLE; BONE INFECTION; CELL PROLIFERATION; CONTROLLED DRUG RELEASE; DRUG COATING; DRUG DELIVERY SYSTEM; ENZYME ACTIVITY; FRACTURE HEALING; HUMAN; HUMAN CELL; MYOBLAST; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL;

EID: 80855130884     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.07.006     Document Type: Article

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