The effects of rhBMP-2 released from biodegradable polyurethane/microsphere composite scaffolds on new bone formation in rat femora

Biomaterials

Volumn 30, Issue 35, 2009, Pages 6768-6779

  Li, Bing ^a,b   Yoshii, Toshitaka ^b   Hafeman, Andrea E ^a,b   Nyman, Jeffry S ^b,c   Wenke, Joseph C ^d   Guelcher, Scott A ^a,b  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c DEPARTMENT OF VETERANS AFFAIRS   (United States)

^d US ARMY INSTITUTE OF SURGICAL RESEARCH   (United States)

Author keywords

BMP (bone morphogenetic protein); Bone regeneration; Drug delivery; In vivo test; Polyurethane

Indexed keywords

BIODEGRADABLE POLYURETHANES; BMP (BONE MORPHOGENETIC PROTEIN); BONE FORMATION; BONE REGENERATION; BONE TISSUE ENGINEERING; BURST RELEASE; COMPOSITE SCAFFOLDS; DELIVERY SYSTEMS; DRY POWDERS; FOAMING REACTIONS; HUMAN BONE MORPHOGENETIC PROTEIN; IN VIVO TEST; MATRIX; OSTEOCONDUCTIVE; PLGA MICROSPHERES; POST-IMPLANTATION; RHBMP-2; SUSTAINED RELEASE; TREATMENT GROUP;

BIOLOGICAL MEMBRANES; DRUG DELIVERY; MICROSPHERES; POWDERS; PROTEINS; SCAFFOLDS; TISSUE ENGINEERING;

BONE;

MICROSPHERE; POLYGLACTIN; POLYURETHAN; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; TISSUE SCAFFOLD;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIODEGRADABILITY; BONE DEFECT; BONE REGENERATION; COMPOSITE MATERIAL; CONTROLLED STUDY; DRY POWDER; FEMUR; IMPLANTATION; MALE; MICROENCAPSULATION; MOUSE; NONHUMAN; OSSIFICATION; PARTICLE SIZE; PRIORITY JOURNAL; RAT;

ANIMALS; BIOCOMPATIBLE MATERIALS; BONE MORPHOGENETIC PROTEIN 2; FEMUR; HUMANS; IMPLANTS, EXPERIMENTAL; MALE; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; OSTEOGENESIS; POLYURETHANES; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; TIME FACTORS; TISSUE SCAFFOLDS;

RATTUS;

EID: 70349871404     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.08.038     Document Type: Article

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