메뉴 건너뛰기




Volumn 17, Issue 13-14, 2011, Pages 1735-1746

Improving bone formation in a rat femur segmental defect by controlling bone morphogenetic protein-2 release

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; COMPUTERIZED TOMOGRAPHY; DEFECTS; FRACTURE; PHARMACOKINETICS; RATS; SCAFFOLDS (BIOLOGY);

EID: 79959555090     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2010.0446     Document Type: Article
Times cited : (138)

References (53)
  • 2
    • 30344432435 scopus 로고    scopus 로고
    • rhBMP-2/calcium phosphate matrix accelerates osteotomy-site healing in a nonhuman primate model at multiple treatment times and concentrations
    • Seeherman, H., Li, R., Bouxsein, M., Kim, H., Li, X. J., Smith-Adaline, E. A., Aiolova, M., and Wozney, J. M. rhBMP-2/calcium phosphate matrix accelerates osteotomy-site healing in a nonhuman primate model at multiple treatment times and concentrations. J Bone Joint Surg 88-A, 144, 2006.
    • (2006) J. Bone Joint Surg. , vol.88 A , pp. 144
    • Seeherman, H.1    Li, R.2    Bouxsein, M.3    Kim, H.4    Li, X.J.5    Smith-Adaline, E.A.6    Aiolova, M.7    Wozney, J.M.8
  • 3
    • 0142210215 scopus 로고    scopus 로고
    • rhBMP-2 injected ina calcium phospahte paste (alpha-BSM) accelerates healing in the rabbit ulnar osteotomy model
    • Li, R. H., Bouxsein, M. L., Blake, C. A., D'Augusta, D., Kim, H., Li, X. L., Wozney, J. M., and Seeherman, H. J. rhBMP-2 injected ina calcium phospahte paste (alpha-BSM) accelerates healing in the rabbit ulnar osteotomy model. J Orthop Res 21, 997, 2001.
    • (2001) J. Orthop. Res. , vol.21 , pp. 997
    • Li, R.H.1    Bouxsein, M.L.2    Blake, C.A.3    D'Augusta, D.4    Kim, H.5    Li, X.L.6    Wozney, J.M.7    Seeherman, H.J.8
  • 4
    • 0036148960 scopus 로고    scopus 로고
    • Osteogenic protein-1 induced bone formation in an infected segmental defect in the rat femur
    • Chen, X. Q., Kidder, L. S., and Lew, W. D. Osteogenic protein-1 induced bone formation in an infected segmental defect in the rat femur. J Orthopaedic Res 20, 142, 2002.
    • (2002) J. Orthopaedic Res. , vol.20 , pp. 142
    • Chen, X.Q.1    Kidder, L.S.2    Lew, W.D.3
  • 5
    • 51449094036 scopus 로고    scopus 로고
    • Dual delivery of an angiogenic and an osteogenic growth factor for bone regeneration in a critical size defect model
    • Patel, Z. S., Young, S., Tabata, Y., Jansen, J. A., Wong, M. E., and Mikos, A. G. Dual delivery of an angiogenic and an osteogenic growth factor for bone regeneration in a critical size defect model. Bone 43, 931, 2008.
    • (2008) Bone , vol.43 , pp. 931
    • Patel, Z.S.1    Young, S.2    Tabata, Y.3    Jansen, J.A.4    Wong, M.E.5    Mikos, A.G.6
  • 6
    • 64549129642 scopus 로고    scopus 로고
    • Effect of autologous BMSCs seeding and BMP-2 delivery on ectopic bone formation in a microsphere/poly (propylene fumarate) composite
    • Kempen, D. H., Kruyt, M. C., Lu, L., Wilson, C. E., Florschutz, A. V., Creemers, L. B., Yaszemski, M. J., and Dhert, W. J. Effect of autologous BMSCs seeding and BMP-2 delivery on ectopic bone formation in a microsphere/poly (propylene fumarate) composite. Tissue Eng Part A 15, 587, 2009.
    • (2009) Tissue Eng. Part A , vol.15 , pp. 587
    • Kempen, D.H.1    Kruyt, M.C.2    Lu, L.3    Wilson, C.E.4    Florschutz, A.V.5    Creemers, L.B.6    Yaszemski, M.J.7    Dhert, W.J.8
  • 9
    • 0031093601 scopus 로고    scopus 로고
    • Bone morphogenetic protein: The molecularization of the skeletal system
    • Urist, M. R. Bone morphogenetic protein: the molecularization of the skeletal system. J Bone Min Res 12, 343, 1997.
    • (1997) J. Bone Min Res. , vol.12 , pp. 343
    • Urist, M.R.1
  • 11
    • 0036035005 scopus 로고    scopus 로고
    • BMP-2, BMP-4, and PDGF-bb stimulate chemotactic migration of primary human mesenchymal progenitor cells
    • Fiedler, J., Roderer, G., Gunther, K. P., and Brenner, R. E. BMP-2, BMP-4, and PDGF-bb stimulate chemotactic migration of primary human mesenchymal progenitor cells. J Cell Biochem 87, 305, 2002.
    • (2002) J. Cell. Biochem. , vol.87 , pp. 305
    • Fiedler, J.1    Roderer, G.2    Gunther, K.P.3    Brenner, R.E.4
  • 12
    • 0012248154 scopus 로고    scopus 로고
    • Delivery systems for BMPS: Factors contributing to the protein retention at an application site
    • Uludag, H., Gao, T., Porter, T., Friess, W., and Wozney, J. Delivery systems for BMPS: factors contributing to the protein retention at an application site. J Bone Joint Surg 83-A, S128, 2001.
    • (2001) J. Bone Joint Surg. , vol.83 A
    • Uludag, H.1    Gao, T.2    Porter, T.3    Friess, W.4    Wozney, J.5
  • 13
    • 21344473040 scopus 로고    scopus 로고
    • Delivery of bone morphogenetic proteins for orthopedic tissue regeneration
    • Seeherman, H., and Wozney, J. M. Delivery of bone morphogenetic proteins for orthopedic tissue regeneration. Cytokine Growth Factor Rev 16, 329, 2005.
    • (2005) Cytokine Growth Factor Rev. , vol.16 , pp. 329
    • Seeherman, H.1    Wozney, J.M.2
  • 14
    • 0036181393 scopus 로고    scopus 로고
    • Differential temporal expression of members of the transforming growth factor beta superfamily during murine fracture healing
    • Cho, T. J., Gerstenfeld, L. C., and Einhorn, T. A. Differential temporal expression of members of the transforming growth factor beta superfamily during murine fracture healing. J Bone Miner Res 17, 513, 2002.
    • (2002) J. Bone Miner. Res. , vol.17 , pp. 513
    • Cho, T.J.1    Gerstenfeld, L.C.2    Einhorn, T.A.3
  • 15
    • 17944404659 scopus 로고    scopus 로고
    • No augmentation of morselized and impacted bone graft by OP-1 in a weight-bearing model
    • Tagil, M., Jeppsson, C., Wang, J. S., and Aspenberg, P. No augmentation of morselized and impacted bone graft by OP-1 in a weight-bearing model. Acta Orthop Scand 74, 742, 2003.
    • (2003) Acta Orthop. Scand. , vol.74 , pp. 742
    • Tagil, M.1    Jeppsson, C.2    Wang, J.S.3    Aspenberg, P.4
  • 18
    • 51449094036 scopus 로고    scopus 로고
    • Dual delivery of an angiogenic and an osteogenic growth factor for bone regeneration in a critical size defect model
    • Patel, Z. S., Young, S., Tabata, Y., Jansen, J. A., Wong, M. E., and Mikos, A. G. Dual delivery of an angiogenic and an osteogenic growth factor for bone regeneration in a critical size defect model. Bone 43, 931, 2008.
    • (2008) Bone , vol.43 , pp. 931
    • Patel, Z.S.1    Young, S.2    Tabata, Y.3    Jansen, J.A.4    Wong, M.E.5    Mikos, A.G.6
  • 19
    • 64549129642 scopus 로고    scopus 로고
    • Effect of autologous bone marrow stromal cell seeding and bone morphogenetic protein-2 delivery on ectopic bone formation in a microsphere/poly (propylene fumarate) composite
    • Kempen, D. H., Kruyt, M. C., Lu, L., Wilson, C. E., Florschutz, A. V., Creemers, L. B., Yaszemski, M. J., and Dhert, W. J. Effect of autologous bone marrow stromal cell seeding and bone morphogenetic protein-2 delivery on ectopic bone formation in a microsphere/poly (propylene fumarate) composite. Tissue Eng Part A 15, 587, 2009.
    • (2009) Tissue Eng. Part A , vol.15 , pp. 587
    • Kempen, D.H.1    Kruyt, M.C.2    Lu, L.3    Wilson, C.E.4    Florschutz, A.V.5    Creemers, L.B.6    Yaszemski, M.J.7    Dhert, W.J.8
  • 20
    • 51849089563 scopus 로고    scopus 로고
    • Orthotopic bone formation by implantation of apatite-coated poly (lactide-co-glycolide)/hydroxyapatite composite particulates and bone morphogenetic protein-2
    • Kim, S. S., Gwak, S. J., and Kim, B. S. Orthotopic bone formation by implantation of apatite-coated poly (lactide-co-glycolide)/hydroxyapatite composite particulates and bone morphogenetic protein-2. J Biomed Mater Res A 87, 245, 2008.
    • (2008) J. Biomed. Mater. Res. A , vol.87 , pp. 245
    • Kim, S.S.1    Gwak, S.J.2    Kim, B.S.3
  • 21
    • 40849083442 scopus 로고    scopus 로고
    • Long-term delivery enhances in vivo osteogenic efficacy of bone morphogenetic protein-2 compared to short-term delivery
    • Jeon, O., Song, S. J., Yang, H. S., Bhang, S. H., Kang, S. W., Sung, M. A, Lee, J. H. and Kim, B. S. Long-term delivery enhances in vivo osteogenic efficacy of bone morphogenetic protein-2 compared to short-term delivery. Biochem Biophys Res Commun 369, 774, 2008.
    • (2008) Biochem. Biophys. Res. Commun. , vol.369 , pp. 774
    • Jeon, O.1    Song, S.J.2    Yang, H.S.3    Bhang, S.H.4    Kang, S.W.5    Sung, M.A.6    Lee, J.H.7    Kim, B.S.8
  • 23
    • 0035400037 scopus 로고    scopus 로고
    • Delivering on the promise of bone morphogenetic proteins
    • Li, R. H., and Wozney, J. M. Delivering on the promise of bone morphogenetic proteins. Trends Biotechnol 19, 255, 2001.
    • (2001) Trends Biotechnol. , vol.19 , pp. 255
    • Li, R.H.1    Wozney, J.M.2
  • 24
    • 73949143647 scopus 로고    scopus 로고
    • Delivery of recombinant bone morphogenetic proteins for bone regeneration and repair. Part B: Delivery systems for BMPs in orthopaedic and craniofacial tissue engineering
    • Haidar, Z. S., Hamdy, R. C., and Tabrizian, M. Delivery of recombinant bone morphogenetic proteins for bone regeneration and repair. Part B: Delivery systems for BMPs in orthopaedic and craniofacial tissue engineering. Biotechnol Lett 31, 1825, 2009.
    • (2009) Biotechnol. Lett. , vol.31 , pp. 1825
    • Haidar, Z.S.1    Hamdy, R.C.2    Tabrizian, M.3
  • 25
    • 73949119177 scopus 로고    scopus 로고
    • Delivery of recombinant bone morphogenetic proteins for bone regeneration and repair. Part A: Current challenges in BMP delivery
    • Haidar, Z. S., Hamdy, R. C., and Tabrizian, M. Delivery of recombinant bone morphogenetic proteins for bone regeneration and repair. Part A: Current challenges in BMP delivery. Biotechnol Lett 31, 1817, 2009.
    • (2009) Biotechnol. Lett. , vol.31 , pp. 1817
    • Haidar, Z.S.1    Hamdy, R.C.2    Tabrizian, M.3
  • 26
    • 34249913427 scopus 로고    scopus 로고
    • Biodegradable elastomeric scaffolds with basic fibroblast growth factor release
    • Guan, J., Stankus, J. J., and Wagner, W. R. Biodegradable elastomeric scaffolds with basic fibroblast growth factor release. J Control Release 120, 70, 2007.
    • (2007) J. Control Release , vol.120 , pp. 70
    • Guan, J.1    Stankus, J.J.2    Wagner, W.R.3
  • 27
    • 67349250425 scopus 로고    scopus 로고
    • The effect of the local delivery of platelet-derived growth factor from reactive two-component polyurethane scaffolds on the healing in rat skin excisional wounds
    • Li, B., Davidson, J. M., and Guelcher, S. A. The effect of the local delivery of platelet-derived growth factor from reactive two-component polyurethane scaffolds on the healing in rat skin excisional wounds. Biomaterials 30, 3486, 2009.
    • (2009) Biomaterials , vol.30 , pp. 3486
    • Li, B.1    Davidson, J.M.2    Guelcher, S.A.3
  • 28
    • 51649125144 scopus 로고    scopus 로고
    • Injectable biodegradable polyurethane scaffolds with release of platelet-derived growth factor for tissue repair and regeneration
    • Hafeman, A., Li, B., Yoshii, T., Zienkiewicz, K., Davidson, J. M., and Guelcher, S. A. Injectable biodegradable polyurethane scaffolds with release of platelet-derived growth factor for tissue repair and regeneration. Pharm Res 25, 2387, 2008.
    • (2008) Pharm. Res. , vol.25 , pp. 2387
    • Hafeman, A.1    Li, B.2    Yoshii, T.3    Zienkiewicz, K.4    Davidson, J.M.5    Guelcher, S.A.6
  • 29
    • 77954309514 scopus 로고    scopus 로고
    • Sustained release of vancomycin from polyurethane scaffolds inhibits infection of bone wounds in a rat femoral segmental defect model
    • Li, B., Brown, K. V., Wenke, J. C., and Guelcher, S. A. Sustained release of vancomycin from polyurethane scaffolds inhibits infection of bone wounds in a rat femoral segmental defect model. J Control Release 145, 221, 2010
    • (2010) J. Control Release , vol.145 , pp. 221
    • Li, B.1    Brown, K.V.2    Wenke, J.C.3    Guelcher, S.A.4
  • 31
    • 0036772732 scopus 로고    scopus 로고
    • Synthesis, biodegradability, and biocompatibility of lysine diisocyanate-glucose polymers
    • Zhang, J. Y., Beckman, E. J, Hu, J., Yuang, G. G., Agarwal, S., and Hollinger, J. O. Synthesis, biodegradability, and biocompatibility of lysine diisocyanate-glucose polymers. Tissue Eng 8, 771, 2002.
    • (2002) Tissue Eng. , vol.8 , pp. 771
    • Zhang, J.Y.1    Beckman, E.J.2    Hu, J.3    Yuang, G.G.4    Agarwal, S.5    Hollinger, J.O.6
  • 32
    • 0034038523 scopus 로고    scopus 로고
    • A new peptide-based urethane polymer: Synthesis, biodegradation, and potential to support cell growth in vitro
    • Zhang J. Y., Beckman, E. J., Piesco, N. J., and Agarwal, S. A new peptide-based urethane polymer: synthesis, biodegradation, and potential to support cell growth in vitro. Biomaterials 21, 1247, 2000.
    • (2000) Biomaterials , vol.21 , pp. 1247
    • Zhang, J.Y.1    Beckman, E.J.2    Piesco, N.J.3    Agarwal, S.4
  • 33
    • 0037097177 scopus 로고    scopus 로고
    • Biodegradable polyurethanes for implants. II. In vitro degradation and calcification of materials from poly (epsilon-caprolactone)-poly (ethylene oxide) diols and various chain extenders
    • Gorna, K., and Gogolewski, S. Biodegradable polyurethanes for implants. II. In vitro degradation and calcification of materials from poly (epsilon-caprolactone)-poly (ethylene oxide) diols and various chain extenders. J Biomed Mater Res 60, 592, 2002.
    • (2002) J. Biomed. Mater. Res. , vol.60 , pp. 592
    • Gorna, K.1    Gogolewski, S.2
  • 35
    • 77956064777 scopus 로고    scopus 로고
    • Synthesis and characterization of an injectable allograft bone/polymer composite bone void filler with tunable mechanical properties
    • Dumas, J. E., Zienkiewicz, K., Tanner, S. A., Prieto, E. M., Bhattacharyya, S., and Guelcher, S. A. Synthesis and characterization of an injectable allograft bone/polymer composite bone void filler with tunable mechanical properties. Tissue Eng Part A 16, 2505, 2010
    • (2010) Tissue Eng. Part A , vol.16 , pp. 2505
    • Dumas, J.E.1    Zienkiewicz, K.2    Tanner, S.A.3    Prieto, E.M.4    Bhattacharyya, S.5    Guelcher, S.A.6
  • 36
    • 34548656406 scopus 로고    scopus 로고
    • Synthesis, in vitro degradation, and mechanical properties of twocomponent poly (ester urethane) urea scaffolds: Effects of water and polyol composition
    • Guelcher, S., Srinivasan, A., Hafeman, A., Gallagher, K., Doctor, J., Khetan, S., McBride, S., and Hollinger, J. Synthesis, In vitro degradation, and mechanical properties of twocomponent poly (ester urethane) urea scaffolds: effects of water and polyol composition. Tissue Eng 13, 2321, 2007.
    • (2007) Tissue Eng. , vol.13 , pp. 2321
    • Guelcher, S.1    Srinivasan, A.2    Hafeman, A.3    Gallagher, K.4    Doctor, J.5    Khetan, S.6    McBride, S.7    Hollinger, J.8
  • 37
    • 70349871404 scopus 로고    scopus 로고
    • The effects of rhBMP-2 released from biodegradable polyurethane/ microsphere composite scaffolds on new bone formation in rat femora
    • Li, B., Yoshii, T., Hafeman, A. E., Nyman, J. S., Wenke, J. C., and Guelcher, S. A. The effects of rhBMP-2 released from biodegradable polyurethane/microsphere composite scaffolds on new bone formation in rat femora. Biomaterials 30, 6768, 2009.
    • (2009) Biomaterials , vol.30 , pp. 6768
    • Li, B.1    Yoshii, T.2    Hafeman, A.E.3    Nyman, J.S.4    Wenke, J.C.5    Guelcher, S.A.6
  • 38
    • 0035319688 scopus 로고    scopus 로고
    • Effects of carrier release kinetics on bone morphogenetic protein-2-induced periodontal regeneration in vivo
    • Talwar, R., Di Silvio, L., Hughes, F. J., and King, G. N. Effects of carrier release kinetics on bone morphogenetic protein-2-induced periodontal regeneration in vivo. J Clin Periodontol 28, 340, 2001.
    • (2001) J. Clin. Periodontol , vol.28 , pp. 340
    • Talwar, R.1    Di Silvio, L.2    Hughes, F.J.3    King, G.N.4
  • 39
    • 0141960886 scopus 로고    scopus 로고
    • Defect repair in the rat mandible with bone morphogenic protein 5 and prostaglandin E1
    • Arosarena, O. A., and Collins, W. L. Defect repair in the rat mandible with bone morphogenic protein 5 and prostaglandin E1. Arch Otolaryngol Head Neck Surg 129, 1125, 2003.
    • (2003) Arch. Otolaryngol. Head Neck Surg. , vol.129 , pp. 1125
    • Arosarena, O.A.1    Collins, W.L.2
  • 40
    • 58249119459 scopus 로고    scopus 로고
    • Micro-computed tomography assessment of fracture healing: Relationships among callus structure, composition, and mechanical function
    • Morgan, E. F., Mason, Z. D., Chien, K. B., Pfeiffer, A. J., Barnes, G. L., Einhorn, T. A., and Gerstenfeld, L. C. Micro-computed tomography assessment of fracture healing: relationships among callus structure, composition, and mechanical function. Bone 44, 335, 2009.
    • (2009) Bone , vol.44 , pp. 335
    • Morgan, E.F.1    Mason, Z.D.2    Chien, K.B.3    Pfeiffer, A.J.4    Barnes, G.L.5    Einhorn, T.A.6    Gerstenfeld, L.C.7
  • 45
    • 40749112395 scopus 로고    scopus 로고
    • Reconstruction of mandibular continuity defects with bone morphogenetic protein-2 (rhBMP-2)
    • Herford, A. S., and Boyne, P. J. Reconstruction of mandibular continuity defects with bone morphogenetic protein-2 (rhBMP-2). J Oral Maxillofac Surg 66, 616, 2008.
    • (2008) J. Oral. Maxillofac. Surg. , vol.66 , pp. 616
    • Herford, A.S.1    Boyne, P.J.2
  • 46
    • 45149105632 scopus 로고    scopus 로고
    • Off-label use of recombinant human bone morphogenetic protein-2 (rhBMP-2) for reconstruction of mandibular bone defects in humans
    • Carter, T. G., Brar, P. S., Tolas, A., and Beirne, O. R. Off-label use of recombinant human bone morphogenetic protein-2 (rhBMP-2) for reconstruction of mandibular bone defects in humans. J Oral Maxillofac Surg 66, 1417, 2008.
    • (2008) J. Oral. Maxillofac. Surg. , vol.66 , pp. 1417
    • Carter, T.G.1    Brar, P.S.2    Tolas, A.3    Beirne, O.R.4
  • 47
    • 0032482163 scopus 로고    scopus 로고
    • Sustained release emphasizing recombinant human bone morphogenetic protein-2
    • Winn, S. R., Uludag, H., and Hollinger, J. O. Sustained release emphasizing recombinant human bone morphogenetic protein-2. Adv Drug Deliv Rev 31, 303, 1998.
    • (1998) Adv. Drug Deliv. Rev. , vol.31 , pp. 303
    • Winn, S.R.1    Uludag, H.2    Hollinger, J.O.3
  • 48
    • 0035929385 scopus 로고    scopus 로고
    • A mathematical framework to study the effects of growth factor influences on fracture healing
    • Bailon-Plaza, A., and van der Meulen, M. C. A mathematical framework to study the effects of growth factor influences on fracture healing. J Theor Biol 212, 191, 2001.
    • (2001) J. Theor Biol. , vol.212 , pp. 191
    • Bailon-Plaza, A.1    Van Der Meulen, M.C.2
  • 50
    • 33947178806 scopus 로고    scopus 로고
    • Enhancement of ectopic bone formation by bone morphogenetic protein-2 released from a heparin-conjugated poly (L-lactic-co-glycolic acid) scaffold
    • Jeon, O., Song, S. J., Kang, S. W., Putnam, A. J., and Kim, B. S. Enhancement of ectopic bone formation by bone morphogenetic protein-2 released from a heparin-conjugated poly (L-lactic-co-glycolic acid) scaffold. Biomaterials 28, 2763, 2007.
    • (2007) Biomaterials , vol.28 , pp. 2763
    • Jeon, O.1    Song, S.J.2    Kang, S.W.3    Putnam, A.J.4    Kim, B.S.5
  • 52


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.