Platelet activation receptor CLEC-2 regulates blood/lymphatic vessel separation by inhibiting proliferation, migration, and tube formation of lymphatic endothelial cells

Journal of Biological Chemistry

Volumn 287, Issue 26, 2012, Pages 22241-22252

  Osada, Makoto ^a   Inoue, Osamu ^a   Ding, Guo ^b   Shirai, Toshiaki ^a   Ichise, Hirotake ^c   Hirayama, Kazuyoshi ^a   Takano, Katsuhiro ^a   Yatomi, Yutaka ^d   Hirashima, Masanori ^b   Fujii, Hideki ^a   Suzuki Inoue, Katsue ^a   Ozaki, Yukio ^a  

^a UNIVERSITY OF YAMANASHI   (Japan)

^b KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED PLATELETS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; LEC; LYMPHANGIOGENESIS; MISCONNECTION; PLATELET ACTIVATION; PLATELET FACTOR-4; SUPERNATANTS; TRANSFORMING GROWTH FACTORS; TUBE FORMATION; TUMOR METASTASIS;

ELECTROCHEMICAL CELLS; ENDOTHELIAL CELLS; SEPARATION; TUBES (COMPONENTS);

PLATELETS;

BONE MORPHOGENETIC PROTEIN 9; C TYPE LECTIN LIKE RECEPTOR 2; LECTIN; THROMBOCYTE FACTOR 4; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BLOOD VESSEL; CELL GRANULE; CELL GROWTH; CELL PROLIFERATION; COCULTURE; CONTROLLED STUDY; EMBRYO; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; LYMPH VESSEL; LYMPHANGIOGENESIS; MIGRATION INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; THROMBOCYTE; THROMBOCYTE ACTIVATION; TUBE FORMATION; UMBILICAL VEIN ENDOTHELIAL CELL;

ANIMALS; BLOOD PLATELETS; CELL MOVEMENT; CELL PROLIFERATION; CROSSES, GENETIC; ENDOTHELIAL CELLS; EXONS; FLOW CYTOMETRY; GROWTH DIFFERENTIATION FACTOR 2; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LECTINS, C-TYPE; LYMPHATIC VESSELS; MEMBRANE GLYCOPROTEINS; MICE; MICE, TRANSGENIC; PLATELET ACTIVATION;

EID: 84862702605     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.329987     Document Type: Article

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