-
1
-
-
0036273081
-
A clinical armamentarium of marine derived anti-cancer compounds
-
Pomponi S A
-
Jimeno J M. A clinical armamentarium of marine derived anti-cancer compounds, Anticancer Drugs, 13 (2002) (suppl 1): S15-19.Pomponi S A
-
(2002)
Anticancer Drugs
, vol.13
, Issue.SUPPL. 1
-
-
Jimeno, J.M.1
-
2
-
-
0033066481
-
-
The bioprocess-technological potential of the sea
-
The bioprocess-technological potential of the sea. J Biotechnol., 70 (1999) 5-13
-
(1999)
J Biotechnol
, vol.70
, pp. 5-13
-
-
-
3
-
-
41349099586
-
Marine Molecular Biology: An Emerging Field of Biological Sciences
-
Narsinh L, Thakur A, Roopesh Jain, Filipe Natalio, Bojan Hamer, Archana N T, Werner E G, Müller, Marine molecular biology: An emerging field of biological sciences. Biotechnol Adv., 26 (2008) 233-24
-
(2008)
Biotechnol Adv
, vol.26
, pp. 233-324
-
-
Narsinh, L.1
Thakur, A.2
Jain, R.3
Natalio, F.4
Hamer, B.5
Archana, N.T.6
Werner, E.G.7
-
5
-
-
0030937882
-
Coral reefs forests, and thermal vents: The worldwide exploration of nature for novel antitumor agents
-
Cragg G M, Newman D J, Weiss R B, Coral reefs, forests, and thermal vents: The worldwide exploration of nature for novel antitumor agents. Semin Oncol., 24 (1997) 156-63
-
(1997)
Semin Oncol
, vol.24
, pp. 156-163
-
-
Cragg, G.M.1
Newman, D.J.2
Weiss, R.B.3
-
6
-
-
0033066481
-
The bioprocess-technological potential of the sea
-
Pomponi A S. The bioprocess-technological potential of the sea. J Biotechnol 70 (1999) 5-13
-
(1999)
J Biotechnol
, vol.70
, pp. 5-13
-
-
Pomponi, A.S.1
-
7
-
-
0025850593
-
Summary of the workshop on drug development, biologic diversity, and economic growth
-
Schweitzer J, Handley F G, Edwards J, Summary of the workshop on drug development, biologic diversity, and economic growth. J Natl Cancer Inst., 83 (1991) 1294-98
-
(1991)
J Natl Cancer Inst
, vol.83
, pp. 1294-1298
-
-
Schweitzer, J.1
Handley, F.G.2
Edwards, J.3
-
8
-
-
0033981511
-
Antitumor compounds from tunicates
-
Rinehart K L, Antitumor compounds from tunicates. Med Res Rev., 20 (2000) 1-27
-
(2000)
Med Res Rev
, vol.20
, pp. 1-27
-
-
Rinehart, K.L.1
-
9
-
-
84898884517
-
-
Molecular biology in marine science. Scientific questions, technological approaches and practical implications. Committee on Molecular Marine Biology, Ocean Studies Board, National Research Council. Washington, D.C. National Academy Press
-
Molecular biology in marine science. Scientific questions, technological approaches and practical implications. Committee on Molecular Marine Biology, Ocean Studies Board, National Research Council. Washington, D.C. National Academy Press; 1994 (http://www.nap.edu/catalog.php?record_id=9119#toc)
-
(1994)
-
-
-
10
-
-
25844502482
-
Plant-based anticancer molecules: A chemical and biological profile of some important leads
-
Vandana Srivastava, Arvind Singh Negi,. Kumar J K, Gupta M M, Suman P, Khanuja S, Plant-based anticancer molecules: A chemical and biological profile of some important leads. Bio & Med Chem., 13 (2005) 5892-5908
-
(2005)
Bio & Med Chem
, vol.13
, pp. 5892-5908
-
-
Srivastava, V.1
Singh, A.2
Kumar, J.K.3
Gupta, M.M.4
Suman, P.5
Khanuja, S.6
-
11
-
-
14844320177
-
Marine natural products
-
Blunt J W, Copp B R, Munro M H G, Northcote P T, Prinsep M R. Marine natural products. Nat Prod Rep., 22 (2005) 15-61
-
(2005)
Nat Prod Rep
, vol.22
, pp. 15-61
-
-
Blunt, J.W.1
Copp, B.R.2
Munro, M.H.G.3
Northcote, P.T.4
Prinsep, M.R.5
-
12
-
-
0036007872
-
Marine natural products
-
Faulkner J. Marine natural products. Nat Prod Rep., 19 (2002) 1-48
-
(2002)
Nat Prod Rep
, vol.19
, pp. 1-48
-
-
Faulkner, J.1
-
13
-
-
4344650390
-
Marine natural products and related compounds in clinical and advanced preclinical trials
-
Newman D J, Cragg G M. Marine natural products and related compounds in clinical and advanced preclinical trials. J Nat Prod., 67 (2004) 1216-38
-
(2004)
J Nat Prod
, vol.67
, pp. 1216-1238
-
-
Newman, D.J.1
Cragg, G.M.2
-
14
-
-
23944453589
-
Marine sponges as pharmacy
-
Sipkema D, Franssen M C, Osinga R, Tramper J, Wijffels R H. Marine sponges as pharmacy. Mar Biotechnol., 7 (2005) 142-62
-
(2005)
Mar Biotechnol
, vol.7
, pp. 142-162
-
-
Sipkema, D.1
Franssen, M.C.2
Osinga, R.3
Tramper, J.4
Wijffels, R.H.5
-
15
-
-
33748125863
-
Marine Pharmacology in 2003-4: Antitumor and cytotoxic compounds
-
Mayer A M S, Gustafson K R, Marine Pharmacology in 2003-4: Antitumor and cytotoxic compounds. Eur J Cancer., 43 (2006) 2241-70
-
(2006)
Eur J Cancer
, vol.43
, pp. 2241-2270
-
-
Mayer, A.M.S.1
Gustafson, K.R.2
-
16
-
-
34247550727
-
Marine pharmacology in 2003-4: Marine compounds with anthelmintic antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiplatelet, antiprotozoal, antituberculosis, and antiviral activities; affecting the cardiovascular, immune and nervous systems, and other miscellaneous mechanisms of action. Comp Biochem Physiol
-
Mayer A M S, Rodríguez A D, Berlinck R G S, Hamann M T. Marine pharmacology in 2003-4: marine compounds with anthelmintic antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiplatelet, antiprotozoal, antituberculosis, and antiviral activities; affecting the cardiovascular, immune and nervous systems, and other miscellaneous mechanisms of action. Comp Biochem Physiol, Toxicol Pharmacol., 145 (2007) 553-81
-
(2007)
Toxicol Pharmacol
, vol.145
, pp. 553-581
-
-
Mayer, A.M.S.1
Rodríguez, A.D.2
Berlinck, R.G.S.3
Hamann, M.T.4
-
17
-
-
33645888731
-
Marine peptides and related compounds in clinical trial
-
Rawat D S, Joshi M C, Joshi P, Atheaya H. Marine peptides and related compounds in clinical trial. Anti-Cancer Agents Med Chem., 6 (2006) 1-8
-
(2006)
Anti-Cancer Agents Med Chem
, vol.6
, pp. 1-8
-
-
Rawat, D.S.1
Joshi, M.C.2
Joshi, P.3
Atheaya, H.4
-
18
-
-
0038461995
-
Drugs from the deep:Marine natural products as drug candidates
-
Haefner B. Drugs from the deep:marine natural products as drug candidates. Drug Discov Today, 8 (2003) 536-44
-
(2003)
Drug Discov Today
, vol.8
, pp. 536-544
-
-
Haefner, B.1
-
19
-
-
0037073188
-
Microbial technologies for the discovery of novel bioactive metabolites
-
Donadio S, Monciardini P, Alduina R, Mazza P, Chiocchini C, Cavaletti L, Microbial technologies for the discovery of novel bioactive metabolites. J Biotechnol., 99 (2002) 187-98
-
(2002)
J Biotechnol
, vol.99
, pp. 187-198
-
-
Donadio, S.1
Monciardini, P.2
Alduina, R.3
Mazza, P.4
Chiocchini, C.5
Cavaletti, L.6
-
20
-
-
18844481269
-
Cloning the soil metagenome: A strategy for accessing the genetic and functional diversity of uncultured microorganisms
-
Rondon M R, August P R, Bettermann A D, Brady S F, Grossman T H, Liles M R, Cloning the soil metagenome: a strategy for accessing the genetic and functional diversity of uncultured microorganisms, Appl Environ Microbiol., 66 (2000) 2541-7
-
(2000)
Appl Environ Microbiol
, vol.66
, pp. 2541-2547
-
-
Rondon, M.R.1
August, P.R.2
Bettermann, A.D.3
Brady, S.F.4
Grossman, T.H.5
Liles, M.R.6
-
21
-
-
1842560595
-
Tapping into microbial diversity
-
Keller M, Zengler K, Tapping into microbial diversity. Nat Rev Microbiol., 2 (2004) 141-50
-
(2004)
Nat Rev Microbiol
, vol.2
, pp. 141-150
-
-
Keller, M.1
Zengler, K.2
-
22
-
-
11844262569
-
New Marine Derived Anticancer Therapeutics - A Journey from the Sea to Clinical Trials
-
Jimeno J, Faircloth G, Fernández Sousa-Faro J M, Scheuer P and Rinehart K. New Marine Derived Anticancer Therapeutics - A Journey from the Sea to Clinical Trials. Mar. Drugs, 1 (2004) 14-29
-
(2004)
Mar. Drugs
, vol.1
, pp. 14-29
-
-
Jimeno, J.1
Faircloth, G.2
Fernández Sousa-Faro, J.M.3
Scheuer, P.4
Rinehart, K.5
-
23
-
-
0030937882
-
Coral reefs, forests and thermal vents: The worldwide exploration of nature for novel antitumor agents
-
Craigg G M, Newman D J, Weiss R B, Coral reefs, forests and thermal vents: The worldwide exploration of nature for novel antitumor agents. Semin. Oncol, 24 (1997) 156-163
-
(1997)
Semin. Oncol
, vol.24
, pp. 156-163
-
-
Craigg, G.M.1
Newman, D.J.2
Weiss, R.B.3
-
24
-
-
3042617137
-
Advanced preclinical and clinical trials of natural products and related compounds from marine sources
-
Newman D J, Cragg G M. Advanced preclinical and clinical trials of natural products and related compounds from marine sources. Curr Med Chem., 11 (2004) 1693-1713
-
(2004)
Curr Med Chem
, vol.11
, pp. 1693-1713
-
-
Newman, D.J.1
Cragg, G.M.2
-
25
-
-
4344650390
-
Marine natural products and related compounds in clinical and advanced preclinical trials
-
Newman D J, Cragg G M. Marine natural products and related compounds in clinical and advanced preclinical trials. J Nat Prod., 67 (2004) 1216-1238
-
(2004)
J Nat Prod
, vol.67
, pp. 1216-1238
-
-
Newman, D.J.1
Cragg, G.M.2
-
27
-
-
19044394540
-
-
ed. Müller, W. E. G.), Springer- Verlag, Berlin
-
Proksch P, Ebel R., Edrada R A, Wray V and Steube K, In Marine Molecular Biotechnology (ed. Müller, W. E. G.), Springer- Verlag, Berlin, (2003) 117-142
-
(2003)
In Marine Molecular Biotechnology
, pp. 117-142
-
-
Proksch, P.1
Ebel, R.2
Edrada, R.A.3
Wray, V.4
Steube, K.5
-
28
-
-
71749104056
-
Anticancer drug discovery in the future: An evolutionary prospective
-
Xianghui Ma, Zhiwen Wang. Anticancer drug discovery in the future: an evolutionary prospective. Drug disco today 14 (23/24), (2009) 1137-1144
-
(2009)
Drug Disco Today
, vol.14
, Issue.23-24
, pp. 1137-1144
-
-
Ma, X.1
Wang, Z.2
-
29
-
-
0036488643
-
Natural products in cancer chemotherapy: Past, present and future
-
Mann J. Natural products in cancer chemotherapy: past, present and future. Nat Rev Cancer, 2 (2002) 143-148
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 143-148
-
-
Mann, J.1
-
30
-
-
0015211527
-
Plant antitumor agents V.I. The isolation and structure of taxol, a novel anti-leukemic and antitumor agent from Taxus breoifolia
-
Wani M C. Plant antitumor agents V.I. The isolation and structure of taxol, a novel anti-leukemic and antitumor agent from Taxus breoifolia. J Am Chem Soc., 93 (1971) 2325-2327
-
(1971)
J Am Chem Soc
, vol.93
, pp. 2325-2327
-
-
Wani, M.C.1
-
31
-
-
0035135713
-
Marine bioprospecting-trawling for treasure and pleasure
-
Capon R J. Marine bioprospecting-trawling for treasure and pleasure. Eur J Org Chem., 9 (2001) 633-645
-
(2001)
Eur J Org Chem
, vol.9
, pp. 633-645
-
-
Capon, R.J.1
-
32
-
-
0038461995
-
Drugs from the deep: Marine natural products as drug candidates
-
Haefner B. Drugs from the deep: marine natural products as drug candidates. Drug Discov Today, 8 (2003) 536-544
-
(2003)
Drug Discov Today
, vol.8
, pp. 536-544
-
-
Haefner, B.1
-
33
-
-
0038461995
-
Drugs from the deep: Marine natural products as drug candidates
-
Haefner, B. Drugs from the deep: Marine natural products as drug candidates. Drug Discov. Today, 8(12) (2003) 536
-
(2003)
Drug Discov. Today
, vol.8
, Issue.12
, pp. 536
-
-
Haefner, B.1
-
34
-
-
0031682217
-
Camptothecin and Taxol: Discovery to clinic
-
Wall M E. Camptothecin and Taxol: discovery to clinic. Med Res Rev., 18 (1998) 299-314
-
(1998)
Med Res Rev
, vol.18
, pp. 299-314
-
-
Wall, M.E.1
-
35
-
-
0346433524
-
Combrestatins: From natural product to drug discovery
-
Cirla A and Mann J. Combrestatins: from natural product to drug discovery. Nat Prod Rep., 20 (2003) 558-564
-
(2003)
Nat Prod Rep
, vol.20
, pp. 558-564
-
-
Cirla, A.1
Mann, J.2
-
36
-
-
0028033859
-
Biological activities of selected marine natural products
-
Konig G M, Wright A D, Sticher O, Angerhofer C K, Pezzuto J M. Biological activities of selected marine natural products. Planta Med., 60 (1994) 532-37
-
(1994)
Planta Med
, vol.60
, pp. 532-537
-
-
Konig, G.M.1
Wright, A.D.2
Sticher, O.3
Angerhofer, C.K.4
Pezzuto, J.M.5
-
37
-
-
0035137292
-
Marine natural products
-
Faulkner D J. Marine natural products. Nat Prod Rep., 18 (2001) 1-49
-
(2001)
Nat Prod Rep
, vol.18
, pp. 1-49
-
-
Faulkner, D.J.1
-
39
-
-
0034185943
-
Podophyllotoxin
-
Canel C. Podophyllotoxin. Phytochemistry, 54 (2000) 115-120
-
(2000)
Phytochemistry
, vol.54
, pp. 115-120
-
-
Canel, C.1
-
40
-
-
0000502679
-
The Vinca alkaloids: A new class of oncolytic agents
-
Johnson, I.S. et al. (1963). The Vinca alkaloids: a new class of oncolytic agents. Cancer Res. 23, 1390
-
(1963)
Cancer Res
, vol.23
, pp. 1390
-
-
Johnson, I.S.1
-
41
-
-
85111441699
-
Drugs and Cosmetics from the Sea
-
Anake Kijjoa and Pichan Sawangwong. Drugs and Cosmetics from the Sea. Mar Drugs, 2 (2004) 73-82
-
(2004)
Mar Drugs
, vol.2
, pp. 73-82
-
-
Kijjoa, A.1
Sawangwong, P.2
-
42
-
-
0035433799
-
Lopes and Gilberto Schwartsmann. Natural products in anticancer therapy
-
Adriana B, Rocha D A, Rafael M, Lopes and Gilberto Schwartsmann. Natural products in anticancer therapy. Current Opinion in Pharmacol., 1(2001) 364-369
-
(2001)
Current Opinion In Pharmacol
, vol.1
, pp. 364-369
-
-
Adriana, B.1
Rocha, D.A.2
Rafael, M.3
-
43
-
-
0033779370
-
Marine organisms and other novel natural sources of new anticancer drugs
-
Schwartsmann G. Marine organisms and other novel natural sources of new anticancer drugs. Ann Oncol., 11 (2000) 235-243
-
(2000)
Ann Oncol
, vol.11
, pp. 235-243
-
-
Schwartsmann, G.1
-
44
-
-
0039923005
-
Marine organisms as a source of new anticancer agents
-
Schwartsmann G, Rocha A B, Berlinck R, Jimeno J: Marine organisms as a source of new anticancer agents. Lancet Oncol., 2 (2001) 221-225
-
(2001)
Lancet Oncol
, vol.2
, pp. 221-225
-
-
Schwartsmann, G.1
Rocha, A.B.2
Berlinck, R.3
Jimeno, J.4
-
45
-
-
0033066481
-
The bioprocess-technological potential of the sea
-
Pomponi A S. The bioprocess-technological potential of the sea. J Biotechnol., 70 (1999) 5-13
-
(1999)
J Biotechnol
, vol.70
, pp. 5-13
-
-
Pomponi, A.S.1
-
46
-
-
0025850593
-
Summary of the workshop on drug development, biological diversity, and economic growth
-
Schweitzer J, Handley F G, Edwards J, Harris W F, Grever M R, Schepartz S A, Cragg G, Snader K, Bhat A. Summary of the workshop on drug development, biological diversity, and economic growth. J Natl Cancer Inst., 83 (1991) 1294-1298
-
(1991)
J Natl Cancer Inst
, vol.83
, pp. 1294-1298
-
-
Schweitzer, J.1
Handley, F.G.2
Edwards, J.3
Harris, W.F.4
Grever, M.R.5
Schepartz, S.A.6
Cragg, G.7
Snader, K.8
Bhat, A.9
-
47
-
-
0033981511
-
Antitumor compounds from tunicates
-
Rinehart K L. Antitumor compounds from tunicates. Med Res Rev., 20 (2000) 1-27
-
(2000)
Med Res Rev
, vol.20
, pp. 1-27
-
-
Rinehart, K.L.1
-
48
-
-
0023026034
-
The first marine compound entering clinical trials as an anti-neoplastic agent
-
Chun H G, Davies B, Hoth D, Suffness M, Plowman J, Flora K, Grieshaber C, Leyland-Jones B: Didemnin B. The first marine compound entering clinical trials as an anti-neoplastic agent. Invest New Drugs, 4 (1986) 279-284
-
(1986)
Invest New Drugs
, vol.4
, pp. 279-284
-
-
Chun, H.G.1
Davies, B.2
Hoth, D.3
Suffness, M.4
Plowman, J.5
Flora, K.6
Grieshaber, C.7
Leyland-Jones, B.8
Didemnin, B.9
-
49
-
-
77349101662
-
Aquaculture, Marine Sciences and Oceanography: A Confluence Connection
-
Halvorson H O. Aquaculture, Marine Sciences and Oceanography: A Confluence Connection. New Engl J Higher Ed Econ Dev, 13 (1998) 28-42
-
(1998)
New Engl J Higher Ed Econ Dev
, vol.13
, pp. 28-42
-
-
Halvorson, H.O.1
-
50
-
-
84898901414
-
-
Lazarovici P, Spira M E, Zlotkin Eliahu Eds, Alaken Inc.: Fort Collins, Colorado
-
Scheuer P J. Marine Metabolites as Drug Leads-Retrospect and Prospect: In Biochemical Aspects of Marine Pharmacology. Lazarovici P, Spira M E, Zlotkin Eliahu Eds, Alaken Inc.: Fort Collins, Colorado, (1996) 1-12
-
(1996)
Marine Metabolites As Drug Leads-Retrospect and Prospect: In Biochemical Aspects of Marine Pharmacology
, pp. 1-12
-
-
Scheuer, P.J.1
-
51
-
-
0023874315
-
Didemnins and Tunichlorin: Novel Natural Products from the Marine Tunicate Trididemnum solidum
-
Rinehart K L, Kishore V, Bible K C, Sakai R., Sullins D W, Li K M. Didemnins and Tunichlorin: Novel Natural Products from the Marine Tunicate Trididemnum solidum. J. Nat. Prod., 51 (1988) 1-21
-
(1988)
J. Nat. Prod
, vol.51
, pp. 1-21
-
-
Rinehart, K.L.1
Kishore, V.2
Bible, K.C.3
Sakai, R.4
Sullins, D.W.5
Li, K.M.6
-
52
-
-
0019470678
-
Structures of the didemnins, antiviral and cytotoxic depsipeptides from a Caribbean tunicate
-
Rinehart K, Gloer J, Cook J, Carter J, Mizsak S, Scahill T. Structures of the didemnins, antiviral and cytotoxic depsipeptides from a Caribbean tunicate. J Am Chem Soc 103 (1987) 1857-9
-
(1987)
J Am Chem Soc
, vol.103
, pp. 1857-1859
-
-
Rinehart, K.1
Gloer, J.2
Cook, J.3
Carter, J.4
Mizsak, S.5
Scahill, T.6
-
53
-
-
14844312905
-
Marine natural products as anticancer drugs
-
T Luke Simmons, Eric Andrianasolo, Kerry McPhail, Patricia Flatt, and William H, Gerwick. Marine natural products as anticancer drugs. Mol Cancer Ther., 4(2) (2005) 333-42
-
(2005)
Mol Cancer Ther
, vol.4
, Issue.2
, pp. 333-342
-
-
Simmons, T.L.1
Andrianasolo, E.2
McPhail, K.3
Flatt, P.4
William, H.5
Gerwick6
-
55
-
-
0033635276
-
Pharmaceutical development of anticancer agents derived from marine sources
-
Nuijen B, Bouma M, Manada C. Pharmaceutical development of anticancer agents derived from marine sources. Anticancer Drugs, 11 (2000) 793-811
-
(2000)
Anticancer Drugs
, vol.11
, pp. 793-811
-
-
Nuijen, B.1
Bouma, M.2
Manada, C.3
-
56
-
-
84898901414
-
-
Lazarovici P, Spira M E, Zlotkin Eliahu Eds, Alaken, Inc Fort Collins, Colorado
-
Scheuer P J. Marine Metabolites as Drug Leads-Retrospect and Prospect: In Biochemical Aspects of Marine Pharmacology. Lazarovici P, Spira M E, Zlotkin Eliahu Eds, Alaken, Inc Fort Collins, Colorado, (1996) 1-12
-
(1996)
Marine Metabolites As Drug Leads-Retrospect and Prospect: In Biochemical Aspects of Marine Pharmacology
, pp. 1-12
-
-
Scheuer, P.J.1
-
58
-
-
0008390132
-
-
Fusetani, N., Ed.; Karger AG: Basel
-
Yamada K Okija M, Kigoshi H, Suenaga K. Cytotoxic Substances from Opisthobranch Molluscs: In Drugs From The Sea; Fusetani, N., Ed.; Karger AG: Basel, (2000) 59-73
-
(2000)
Cytotoxic Substances From Opisthobranch Molluscs: In Drugs From the Sea
, pp. 59-73
-
-
Yamada, K.1
Okija, M.2
Kigoshi, H.3
Suenaga, K.4
-
59
-
-
0032925417
-
The dolastatins, a family of promising antineoplastic agents
-
Poncet J. The dolastatins, a family of promising antineoplastic agents. Curr Pharm Des., 5 (1999) 139-62
-
(1999)
Curr Pharm Des
, vol.5
, pp. 139-162
-
-
Poncet, J.1
-
60
-
-
0039923005
-
Marine organisms as a source of new anticancer agents
-
Gilberto Schwartsmann, Adriana Brondani da Rocha, Roberto GS, Berlinck and Jose Jimeno. Marine organisms as a source of new anticancer agents. Lancet Oncol., 2 (2001) 221-25
-
(2001)
Lancet Oncol
, vol.2
, pp. 221-225
-
-
Schwartsmann, G.1
da Rocha, A.B.2
Roberto, G.S.3
Berlinck4
Jimeno, J.5
-
61
-
-
0025352537
-
Dolastatin 10, A powerful cytostatic peptide derived from a marine animal. Inhibition of tubulin polymerization mediated through the vinca alkaloid binding domain
-
Bai R, Pettit G R, Hamel E. Dolastatin 10, a powerful cytostatic peptide derived from a marine animal. Inhibition of tubulin polymerization mediated through the vinca alkaloid binding domain. Biochem Pharmacol., 39 (1990) 1941-49
-
(1990)
Biochem Pharmacol
, vol.39
, pp. 1941-1949
-
-
Bai, R.1
Pettit, G.R.2
Hamel, E.3
-
62
-
-
0031912028
-
Dolastatin-10 induces polyploidy, telomeric associations and apoptosis in a murine melanoma cell line
-
Pathak S. Dolastatin-10 induces polyploidy, telomeric associations and apoptosis in a murine melanoma cell line. Oncol Rep., 5 (1998) 373-76
-
(1998)
Oncol Rep
, vol.5
, pp. 373-376
-
-
Pathak, S.1
-
63
-
-
0032611152
-
Clinical trials referral resource, Clinical trials of dolastatin-10
-
Wright J J, Blatner G, Cheson B D. Clinical trials referral resource, Clinical trials of dolastatin-10. Oncology, 3 (1999) 68-70
-
(1999)
Oncology
, vol.3
, pp. 68-70
-
-
Wright, J.J.1
Blatner, G.2
Cheson, B.D.3
-
64
-
-
0034005620
-
Novel marine-derived anticancer agents: A phase I clinical, pharmacological, and pharmacodynamic study of dolastatin 10 (NSC 376128) in patients with advanced solid tumors
-
Madden T, Tran H T, Beck D. Novel marine-derived anticancer agents: a phase I clinical, pharmacological, and pharmacodynamic study of dolastatin 10 (NSC 376128) in patients with advanced solid tumors. Clin Cancer Res., 6 (2000) 1293-301
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1293-1301
-
-
Madden, T.1
Tran, H.T.2
Beck, D.3
-
65
-
-
0032859724
-
The rational design of potential chemotherapeutic agents: Synthesis of bryostatin analogues
-
Wender P A, Hinkle K W, Koehler M F, Lippa B. The rational design of potential chemotherapeutic agents: synthesis of bryostatin analogues. Med Res Rev., 19 (1999) 388-407
-
(1999)
Med Res Rev
, vol.19
, pp. 388-407
-
-
Wender, P.A.1
Hinkle, K.W.2
Koehler, M.F.3
Lippa, B.4
-
66
-
-
0034093431
-
Phase II study of dolastatin-10 in patients with advanced non-small-cell lung cancer
-
Krug L M, Miller V A, Kalemkerian G P. Phase II study of dolastatin-10 in patients with advanced non-small-cell lung cancer. Ann Oncol., 11 (2000) 227-28
-
(2000)
Ann Oncol
, vol.11
, pp. 227-228
-
-
Krug, L.M.1
Miller, V.A.2
Kalemkerian, G.P.3
-
67
-
-
0020408957
-
Isolation and structure of bryostatin-1
-
Pettit G R. Isolation and structure of bryostatin-1. J Am Chem Soc., 104 (1982) 6846-48
-
(1982)
J Am Chem Soc
, vol.104
, pp. 6846-6848
-
-
Pettit, G.R.1
-
68
-
-
0023865665
-
Immunomodulating properties of a novel series of protein kinase C activators. The bryostatins
-
Trenn G. Immunomodulating properties of a novel series of protein kinase C activators. The bryostatins. J Immunol., 140 (1988) 433-39
-
(1988)
J Immunol
, vol.140
, pp. 433-439
-
-
Trenn, G.1
-
69
-
-
0030612225
-
Antitumor activity of TZT-1027, a novel dolastatin 10 derivative
-
Kobayashi M, Natsume T, Tamaoki S. Antitumor activity of TZT-1027, a novel dolastatin 10 derivative. Jpn J Cancer Re., 88 (1997) 316-27
-
(1997)
Jpn J Cancer Re
, vol.88
, pp. 316-327
-
-
Kobayashi, M.1
Natsume, T.2
Tamaoki, S.3
-
70
-
-
0026532012
-
Preclinical evaluation of bryostatin as an anticancer agent against several murine tumor cell lines: In vitro and in vivo activity
-
Hornung R L. Preclinical evaluation of bryostatin as an anticancer agent against several murine tumor cell lines: in vitro and in vivo activity. Cancer Res., 52 (1992) 101-07
-
(1992)
Cancer Res
, vol.52
, pp. 101-107
-
-
Hornung, R.L.1
-
71
-
-
0031982782
-
Phase I study of bryostatin-1 in patients with relapsed non-Hodgkińs lymphoma and chronic lymphocytic leukemia
-
Varterasian M.L. Phase I study of bryostatin-1 in patients with relapsed non-Hodgkińs lymphoma and chronic lymphocytic leukemia. J Clin Oncol., 16 (1998) 56-62
-
(1998)
J Clin Oncol
, vol.16
, pp. 56-62
-
-
Varterasian, M.L.1
-
72
-
-
0029084804
-
A phase I trial of bryostatin 1 in patients with advanced malignancies using a hour intravenous infusion
-
Jayson G C. A phase I trial of bryostatin 1 in patients with advanced malignancies using a hour intravenous infusion. Br J Cancer., 72 (1995) 461-68
-
(1995)
Br J Cancer
, vol.72
, pp. 461-468
-
-
Jayson, G.C.1
-
73
-
-
0027326957
-
A phase I study of intravenous bryostatin 1 in patients with advanced cancer
-
Prendiville J. A phase I study of intravenous bryostatin 1 in patients with advanced cancer. Br J Cancer, 68 (1993) 418-24
-
(1993)
Br J Cancer
, vol.68
, pp. 418-424
-
-
Prendiville, J.1
-
74
-
-
0031760304
-
A phase II study of bryostatin 1 in metastatic malignant melanoma
-
Propper D J, Macaulay V, Obyrne K J. A phase II study of bryostatin 1 in metastatic malignant melanoma. Br J Cancer, 78 (1998) 1337-41
-
(1998)
Br J Cancer
, vol.78
, pp. 1337-1341
-
-
Propper, D.J.1
Macaulay, V.2
Obyrne, K.J.3
-
75
-
-
0035225541
-
Nitrogen-containing metabolites from marine cyanobacteria
-
In: Cordell G, editor, San Diego: Academic Press
-
Gerwick W H, Tan L T, Sitachitta N. Nitrogen-containing metabolites from marine cyanobacteria. In: Cordell G, editor. The alkaloids. San Diego: Academic Press, (2001) 75-184
-
(2001)
The Alkaloids
, pp. 75-184
-
-
Gerwick, W.H.1
Tan, L.T.2
Sitachitta, N.3
-
76
-
-
0032822307
-
A new cyclic depsipeptide from the hawaiian green alga bryopsis species
-
Kan Y, Fujita T, Sakamoto B, A new cyclic depsipeptide from the hawaiian green alga bryopsis species. J Nat Prod., 62 (1999) 1169-72
-
(1999)
J Nat Prod
, vol.62
, pp. 1169-1172
-
-
Kan, Y.1
Fujita, T.2
Sakamoto, B.3
-
77
-
-
0033891960
-
Antitumor activity of cryptophycins: Effect of infusion time and combination studies
-
Menon K, Alvarez E, Forler P, Antitumor activity of cryptophycins: Effect of infusion time and combination studies. Cancer Chemother Pharmacol., 46 (2000) 142-49
-
(2000)
Cancer Chemother Pharmacol
, vol.46
, pp. 142-149
-
-
Menon, K.1
Alvarez, E.2
Forler, P.3
-
78
-
-
0029842550
-
Kahalalides: Bioactive peptides from a marine mollusk Elysia rufescens and its algal diet Bryopsis sp
-
Hamann M T, Otto C S, Scheuer P J. Kahalalides: bioactive peptides from a marine mollusk Elysia rufescens and its algal diet Bryopsis sp. J Org Chem., 61 (1996) 6594-660
-
(1996)
J Org Chem
, vol.61
, pp. 6594-6660
-
-
Hamann, M.T.1
Otto, C.S.2
Scheuer, P.J.3
-
79
-
-
0027296890
-
A bioactive depsipeptide from the sacoglossan mollusk Elysia rufescens and the green alga Bryopsis sp
-
Hamann M T, Scheuer P J. Kahalalide F: A bioactive depsipeptide from the sacoglossan mollusk Elysia rufescens and the green alga Bryopsis sp. J Am Chem Soc., 115 (1993) 5825-6
-
(1993)
J Am Chem Soc
, vol.115
, pp. 5825-5826
-
-
Hamann, M.T.1
Scheuer, P.J.2
Kahalalide, F.3
-
80
-
-
0035930006
-
Synthesis and structure determination of Kahalalide F
-
Lopez-Macia A, Jimenez J C, Royo M, Giralt E, Albericio F. Synthesis and structure determination of Kahalalide F. J Am Chem Soc., 123 (2001) 11398-401
-
(2001)
J Am Chem Soc
, vol.123
, pp. 11398-11401
-
-
Lopez-Macia, A.1
Jimenez, J.C.2
Royo, M.3
Giralt, E.4
Albericio, F.5
-
81
-
-
0010695085
-
Selective antitumor activity of Kahalalide F, a marine-derived cyclic depsipeptide
-
Faircloth G T, Smith B, Grant W, Selective antitumor activity of Kahalalide F, a marine-derived cyclic depsipeptide. Proc Am Assoc Cancer Res., 42 (2001) 1140
-
(2001)
Proc Am Assoc Cancer Res
, vol.42
, pp. 1140
-
-
Faircloth, G.T.1
Smith, B.2
Grant, W.3
-
82
-
-
0031028432
-
Natural products in drug discovery and development
-
Cragg G M, Newman D J, Snader K M, et al. Natural products in drug discovery and development. J Nat Prod., 60 (1997) 52-60
-
(1997)
J Nat Prod
, vol.60
, pp. 52-60
-
-
Cragg, G.M.1
Newman, D.J.2
Snader, K.M.3
-
83
-
-
0027420205
-
Anticancer drug screening and discovery in the 1990s: A European perspective
-
Schwartsmann G, Workmann P. Anticancer drug screening and discovery in the 1990s: A European perspective. Eur J Cancer., 29 (1993) 3-14
-
Eur J Cancer
, vol.29
, Issue.1993
, pp. 3-14
-
-
Schwartsmann, G.1
Workmann, P.2
-
84
-
-
0033779370
-
Marine organisms and other novel natural sources of new cancer drugs
-
Schwartsmann G. Marine organisms and other novel natural sources of new cancer drugs. Ann Oncol., 11 (2000) 235-43
-
(2000)
Ann Oncol
, vol.11
, pp. 235-243
-
-
Schwartsmann, G.1
-
85
-
-
0032968718
-
Discovery and development of anti-neoplastic agents from natural sources
-
Cragg G M, Newman D J. Discovery and development of anti-neoplastic agents from natural sources. Cancer Invest., 17 (1999) 153-63
-
(1999)
Cancer Invest
, vol.17
, pp. 153-163
-
-
Cragg, G.M.1
Newman, D.J.2
-
86
-
-
0030891357
-
Promising new agents under development by the Division of Cancer Treatment, Diagnosis and Centers of the National Cancer Institute
-
Christian M C, Pluda J M, Ho T C, Promising new agents under development by the Division of Cancer Treatment, Diagnosis and Centers of the National Cancer Institute. Semin Oncol., 24 (1997) 219-40
-
(1997)
Semin Oncol
, vol.24
, pp. 219-240
-
-
Christian, M.C.1
Pluda, J.M.2
Ho, T.C.3
-
87
-
-
0037865214
-
Marine natural products and their potential applications as anti-infective agents
-
Marwa Donia and Mark T Hamann. Marine natural products and their potential applications as anti-infective agents. Lancet Infect Dis., 3 (2003) 338-48
-
(2003)
Lancet Infect Dis
, vol.3
, pp. 338-348
-
-
Donia, M.1
Hamann, M.T.2
-
88
-
-
0002224261
-
Conotoxin MVIIA: From marine snail venom to analgesic drug
-
In: Fusetani N, ed., Basel: Karger
-
Olivera B M. Conotoxin MVIIA: from marine snail venom to analgesic drug. In: Fusetani N, ed. Drugs from the sea. Basel: Karger, (2000) 74-85
-
(2000)
Drugs From the Sea
, pp. 74-85
-
-
Olivera, B.M.1
-
89
-
-
0002829177
-
Aquacultural production of bryostatin 1 and ecteinascidin 743
-
In: Fusetani N, ed., Basel: Karger
-
Mendola D. Aquacultural production of bryostatin 1 and ecteinascidin 743. In: Fusetani N, ed. Drugs from the sea. Basel: Karger, (2000) 120-33
-
(2000)
Drugs From the Sea
, pp. 120-133
-
-
Mendola, D.1
-
90
-
-
0000393614
-
Electron microscope study of the association between some sponges and bacteria
-
Vacelet J, Donadey C. Electron microscope study of the association between some sponges and bacteria. J Exp Mar Ecol., 30 (1977) 301-14
-
(1977)
J Exp Mar Ecol
, vol.30
, pp. 301-314
-
-
Vacelet, J.1
Donadey, C.2
-
91
-
-
65049089754
-
Natural compounds for cancer treatment and prevention
-
Stefania Nobili, Donatella Lippib, Ewa Witortc, Martino Donninic, Letizia Bausi, Enrico Minia, Sergio Capaccioli. Natural compounds for cancer treatment and prevention. Pharmacol Res., 59 (2009) 365-378
-
(2009)
Pharmacol Res
, vol.59
, pp. 365-378
-
-
Nobili, S.1
Lippib, D.2
Witortc, E.3
Donninic, M.4
Bausi, L.5
Minia, E.6
Capaccioli, S.7
-
92
-
-
0038219974
-
Gustafson K R Marine pharmacology in 2000: Anti-tumour and cytotoxicity compounds
-
Mayer A M, Gustafson K R Marine pharmacology in 2000: anti-tumour and cytotoxicity compounds. Int J cancer, 105 (2003) 291-299
-
(2003)
Int J Cancer
, vol.105
, pp. 291-299
-
-
Mayer, A.M.1
-
93
-
-
0028280599
-
8-hydroxymanzamine A a beta-carboline alkaloids from a sponge, Pachypellina sp
-
Ichiba T, Corgiat J M, Scheuer P J, Kelly-Borges M. 8-hydroxymanzamine A, a beta-carboline alkaloids from a sponge, Pachypellina sp. J Nat Prod., 57 (1994) 168-170
-
(1994)
J Nat Prod
, vol.57
, pp. 168-170
-
-
Ichiba, T.1
Corgiat, J.M.2
Scheuer, P.J.3
Kelly-Borges, M.4
-
94
-
-
0029906190
-
Four new bioactive manzamine-type alkaloids from the Philippine marine sponges Xestopongia ashmorica
-
Edrada R A, Proksch P, Wray V, Witte L, Muller W E, Van Soest R W. Four new bioactive manzamine-type alkaloids from the Philippine marine sponges Xestopongia ashmorica. J Nat Prod., 59 (1996) 1056-1060
-
(1996)
J Nat Prod
, vol.59
, pp. 1056-1060
-
-
Edrada, R.A.1
Proksch, P.2
Wray, V.3
Witte, L.4
Muller, W.E.5
van Soest, R.W.6
-
95
-
-
0034081287
-
In vitro antimicrobial activity of the beta-carboline alkaloid manzamine A
-
Ang K K, Holmes M J, Higa T, Hamann M T, Kara U A (2000). In vitro antimicrobial activity of the beta-carboline alkaloid manzamine A. Antimicrob Agents Chemother., 44 (2000) 1645-1649
-
(2000)
Antimicrob Agents Chemother
, vol.44
, Issue.2000
, pp. 1645-1649
-
-
Ang, K.K.1
Holmes, M.J.2
Higa, T.3
Hamann, M.T.4
Kara, U.A.5
-
96
-
-
0034907394
-
Immunemediated parasite clearancein mice infected with Plasmodium berghei following treatment with manzamine A
-
Ang K K, Holmes M J, Higa T, Kara U A (2001). Immunemediated parasite clearancein mice infected with Plasmodium berghei following treatment with manzamine A. Parasitol Res., 87 (2001) 715-721
-
(2001)
Parasitol Res
, vol.87
, Issue.2001
, pp. 715-721
-
-
Ang, K.K.1
Holmes, M.J.2
Higa, T.3
Kara, U.A.4
-
97
-
-
3042643058
-
New manzamine alkaloids from an Indo-Pacific sponge. Pharmacokinetics, oral availability, and the significant activity of several manzamines against HIV-I, AIDS opportunistic infections and inflammatory diseases
-
Yousuf M, Hammond N L, Peng J, Wahyuono S, Mclntosh K A, Charman W N, Mayer A M, Hamann M T. New manzamine alkaloids from an Indo-Pacific sponge. Pharmacokinetics, oral availability, and the significant activity of several manzamines against HIV-I, AIDS opportunistic infections and inflammatory diseases. J Med Chem., 47 (2004) 3512-3517
-
(2004)
J Med Chem
, vol.47
, pp. 3512-3517
-
-
Yousuf, M.1
Hammond, N.L.2
Peng, J.3
Wahyuono, S.4
McLntosh, K.A.5
Charman, W.N.6
Mayer, A.M.7
Hamann, M.T.8
-
98
-
-
0034798577
-
Perspectives in cancer chemotherapy
-
doi:10.1158/0008-5472.CAN-08-1490
-
Garattini S, La Vecchia C. Perspectives in cancer chemotherapy. Eur J Cancer., 37 (2001) (Suppl 8):S128-47, doi:10.1158/0008-5472.CAN-08-1490
-
(2001)
Eur J Cancer
, vol.37
, Issue.SUPPL. 8
-
-
Garattini, S.1
la Vecchia, C.2
-
99
-
-
54249098684
-
Vitamin C antagonizes the cytotoxic effects of anti-neoplastic drugs
-
Heaney M L, Gardner J R, Karasavvas N, Golde D W, Scheinberg D A, Smith E A, et al. Vitamin C antagonizes the cytotoxic effects of anti-neoplastic drugs. Cancer Res., 68 (2008) 8031-8
-
(2008)
Cancer Res
, vol.68
, pp. 8031-8038
-
-
Heaney, M.L.1
Gardner, J.R.2
Karasavvas, N.3
Golde, D.W.4
Scheinberg, D.A.5
Smith, E.A.6
-
100
-
-
49649109597
-
C and cancer revisited
-
doi:10.1073/pnas.0806433105
-
Frei B, Lawson S. Vitamin C and cancer revisited. Proc Natl Acad Sci USA, 105 (2008) 11037-8, doi:10.1073/pnas.0806433105
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 11037-11038
-
-
Frei, B.1
Vitamin, L.S.2
-
101
-
-
0002256581
-
Symbiotic bacteria in sponges: Sources of bioactive substances
-
In: Fusetani N, editor, Switz: S. Karger A G
-
Faulkner D J, Harper M K, Haygood M G. Symbiotic bacteria in sponges: sources of bioactive substances. In: Fusetani N, editor. Drugs from the sea. Basel, Switz: S. Karger A G, (2000) 107-19
-
(2000)
Drugs From the Sea. Basel
, pp. 107-119
-
-
Faulkner, D.J.1
Harper, M.K.2
Haygood, M.G.3
-
102
-
-
0031868508
-
Cellular origin of chlorinated diketopiperazines in the dictyoceratid sponge Dysidea herbacea (Keller)
-
Flowers A, Garson M J, Webb R, Dumdei E, Charan R. Cellular origin of chlorinated diketopiperazines in the dictyoceratid sponge Dysidea herbacea (Keller). Cell Tissue Res., 292 (1998) 597-607
-
(1998)
Cell Tissue Res
, vol.292
, pp. 597-607
-
-
Flowers, A.1
Garson, M.J.2
Webb, R.3
Dumdei, E.4
Charan, R.5
-
103
-
-
12044249354
-
Cyanobacterial symbiont biosynthesis of chlorinated metabolites from Dysidea herbacea (Porifera)
-
Unson M D, Faulkner D J. Cyanobacterial symbiont biosynthesis of chlorinated metabolites from Dysidea herbacea (Porifera). Experientia., 49 (1993) 349-53
-
(1993)
Experientia
, vol.49
, pp. 349-353
-
-
Unson, M.D.1
Faulkner, D.J.2
-
104
-
-
0029969534
-
Barbamide, a chlorinated metabolite with molluscicidal activity from the Caribbean cyanobacterium Lyngbya majuscula
-
Orjala J O, Gerwick W H. Barbamide, a chlorinated metabolite with molluscicidal activity from the Caribbean cyanobacterium Lyngbya majuscula. J Nat Prod., 59 (1996) 427-30
-
(1996)
J Nat Prod
, vol.59
, pp. 427-430
-
-
Orjala, J.O.1
Gerwick, W.H.2
-
105
-
-
0642318239
-
A new marine derived compound induces oncosis in human prostate and breast cancer cells
-
Suarez Y, Gonzalez L, Cuadrado A, Berciano M., Lafarga M., Muñoz A, Kahalalide F, a new marine derived compound induces oncosis in human prostate and breast cancer cells. Mol. Cancer Therapeutics., (2003) 863-872
-
(2003)
Mol. Cancer Therapeutics
, pp. 863-872
-
-
Suarez, Y.1
Gonzalez, L.2
Cuadrado, A.3
Berciano, M.4
Lafarga, M.5
Muñoz, A.6
Kahalalide, F.7
-
106
-
-
32644462594
-
Aaptamine, a spongean alkaloid, activates p21 promoter in a p53-independent manner
-
Aoki S, Kong D, Suna H, Sowa Y, Sakai T, Setiawan A. Aaptamine, a spongean alkaloid, activates p21 promoter in a p53-independent manner. Biochem Biophys Res Commun., 342(1) (2006) 101-6
-
(2006)
Biochem Biophys Res Commun
, vol.342
, Issue.1
, pp. 101-106
-
-
Aoki, S.1
Kong, D.2
Suna, H.3
Sowa, Y.4
Sakai, T.5
Setiawan, A.6
-
107
-
-
33750683958
-
A functional role of intracellular loops of human multidrug resistance protein 1
-
(Tokyo)
-
Ren X Q, Furukawa T, Yamamoto M, Aoki S, Kobayashi M, Nakagawa M. A functional role of intracellular loops of human multidrug resistance protein 1. J Biochem., (Tokyo) 140(3) (2006) 313-8
-
(2006)
J Biochem.
, vol.140
, Issue.3
, pp. 313-318
-
-
Ren, X.Q.1
Furukawa, T.2
Yamamoto, M.3
Aoki, S.4
Kobayashi, M.5
Nakagawa, M.6
-
108
-
-
23144458156
-
Ascididemin and meridine stabilise G-quadruplexes and inhibit telomerase in vitro
-
Guittat L, De C A, Rosu F, Gabelica V, De P E, Delfourne E. Ascididemin and meridine stabilise G-quadruplexes and inhibit telomerase in vitro. Biochim Biophys Acta., 1724(3) (2005) 375-84
-
(2005)
Biochim Biophys Acta
, vol.1724
, Issue.3
, pp. 375-384
-
-
Guittat, L.1
De, C.A.2
Rosu, F.3
Gabelica, V.4
De, P.E.5
Delfourne, E.6
-
109
-
-
31444433185
-
Structure basis for antitumor effect of aplyronine a
-
Hirata K, Muraoka S, Suenaga K, Kuroda T, Kato K, Tanaka H, Structure basis for antitumor effect of aplyronine a. J Mol Biol., 356(4) (2006) 945-54
-
(2006)
J Mol Biol
, vol.356
, Issue.4
, pp. 945-954
-
-
Hirata, K.1
Muraoka, S.2
Suenaga, K.3
Kuroda, T.4
Kato, K.5
Tanaka, H.6
-
110
-
-
37749006846
-
Marine sponge-derived polymeric alkylpyridinium salts as a novel tumor chemotherapeutic targeting the cholinergic system in lung tumors
-
Paleari L, Trombino S, Falugi C, Gallus L, Carlone S, Angelini C, Marine sponge-derived polymeric alkylpyridinium salts as a novel tumor chemotherapeutic targeting the cholinergic system in lung tumors. Int J Oncol 29(6) (2006) 1381-8
-
(2006)
Int J Oncol
, vol.29
, Issue.6
, pp. 1381-1388
-
-
Paleari, L.1
Trombino, S.2
Falugi, C.3
Gallus, L.4
Carlone, S.5
Angelini, C.6
-
111
-
-
33645214617
-
Oxidation and inactivation of low molecular weight protein tyrosine phosphatase by the anticancer drug Aplidin
-
Taddei M L, Chiarugi P, Cuevas C, Ramponi G, Raugei G. Oxidation and inactivation of low molecular weight protein tyrosine phosphatase by the anticancer drug Aplidin. Int J Cancer., 118(8) (2006) 2082-8
-
(2006)
Int J Cancer
, vol.118
, Issue.8
, pp. 2082-2088
-
-
Taddei, M.L.1
Chiarugi, P.2
Cuevas, C.3
Ramponi, G.4
Raugei, G.5
-
112
-
-
33644526581
-
Overexpression of PKCepsilon sensitizes LNCaP human prostate cancer cells to induction of apoptosis by bryostatin 1
-
Powell C T, Yin L. Overexpression of PKCepsilon sensitizes LNCaP human prostate cancer cells to induction of apoptosis by bryostatin 1. Int J Cancer., 118(6) (2006) 1572-6
-
(2006)
Int J Cancer
, vol.118
, Issue.6
, pp. 1572-1576
-
-
Powell, C.T.1
Yin, L.2
-
113
-
-
33646085774
-
Bastadin 6, a spongean brominated tyrosine derivative, inhibits tumor angiogenesis by inducing selective apoptosis to endothelial cells
-
Aoki S, Cho S H, Ono M, Kuwano T, Nakao S, Kuwano M, Bastadin 6, a spongean brominated tyrosine derivative, inhibits tumor angiogenesis by inducing selective apoptosis to endothelial cells. Anticancer Drugs, 17(3) (2006) 269-78
-
(2006)
Anticancer Drugs
, vol.17
, Issue.3
, pp. 269-278
-
-
Aoki, S.1
Cho, S.H.2
Ono, M.3
Kuwano, T.4
Nakao, S.5
Kuwano, M.6
-
114
-
-
33644806057
-
Actin is the primary cellular receptor of bistramide A
-
Statsuk A V, Bai R, Baryza J L, Verma V A, Hamel E, Wender P A, Actin is the primary cellular receptor of bistramide A. Nat Chem Biol., 1(7) (2005) 383-8
-
(2005)
Nat Chem Biol
, vol.1
, Issue.7
, pp. 383-388
-
-
Statsuk, A.V.1
Bai, R.2
Baryza, J.L.3
Verma, V.A.4
Hamel, E.5
Wender, P.A.6
-
115
-
-
33645453004
-
Structure of bistramide A-actin complex at a 135 angstroms resolution
-
Rizvi S A, Tereshko V, Kossiakoff A A, Kozmin S A. Structure of bistramide A-actin complex at a 135 angstroms resolution. J Am Chem Soc., 128(12) (2006) 3882-3
-
(2006)
J Am Chem Soc
, vol.128
, Issue.12
, pp. 3882-3883
-
-
Rizvi, S.A.1
Tereshko, V.2
Kossiakoff, A.A.3
Kozmin, S.A.4
-
116
-
-
24344433558
-
Induction of endoplasmic reticulum stress and apoptosis by a marine prostanoid in human hepatocellular carcinoma
-
Chiang P C, Chien C L, Pan S L, Chen W P, Teng C M, Shen Y C, Induction of endoplasmic reticulum stress and apoptosis by a marine prostanoid in human hepatocellular carcinoma. J Hepatol., 43(4) (2005) 679-86
-
(2005)
J Hepatol
, vol.43
, Issue.4
, pp. 679-686
-
-
Chiang, P.C.1
Chien, C.L.2
Pan, S.L.3
Chen, W.P.4
Teng, C.M.5
Shen, Y.C.6
-
117
-
-
17844364586
-
Cephalostatin 1 inactivates Bcl-2 by hyperphosphorylation independent of M-phase arrest and DNA damage
-
Muller I M, Dirsch V M, Rudy A, Lopez-Anton N, Pettit G R, Vollmar A M. Cephalostatin 1 inactivates Bcl-2 by hyperphosphorylation independent of M-phase arrest and DNA damage. Mol Pharmacol., 67(5) (2005) 1684-9
-
(2005)
Mol Pharmacol
, vol.67
, Issue.5
, pp. 1684-1689
-
-
Muller, I.M.1
Dirsch, V.M.2
Rudy, A.3
Lopez-Anton, N.4
Pettit, G.R.5
Vollmar, A.M.6
-
118
-
-
33644946432
-
B, C and D, anti-angiogenic steroidal alkaloids, from the marine sponge Corticium simplex
-
Aoki S, Watanabe Y, Sanagawa M, Setiawan A, Kotoku N, Kobayashi M. Cortistatins A, B, C and D, anti-angiogenic steroidal alkaloids, from the marine sponge Corticium simplex. J Am Chem Soc., 128(10) (2006) 3148-9
-
(2006)
J Am Chem Soc
, vol.128
, Issue.10
, pp. 3148-3149
-
-
Aoki, S.1
Watanabe, Y.2
Sanagawa, M.3
Setiawan, A.4
Kotoku, N.5
Kobayashi, M.6
Cortistatins, A.7
-
119
-
-
27744476031
-
Tubulin assembly, taxoid site binding, and cellular effects of the microtubule-stabilizing agent dictyostatin
-
Madiraju C, Edler M C, Hamel E, Raccor B S, Balachandran R, Zhu G, Tubulin assembly, taxoid site binding, and cellular effects of the microtubule-stabilizing agent dictyostatin. Biochemistry; 44 (45) (2005) 15053-63
-
(2005)
Biochemistry
, vol.44
, Issue.45
, pp. 15053-15063
-
-
Madiraju, C.1
Edler, M.C.2
Hamel, E.3
Raccor, B.S.4
Balachandran, R.5
Zhu, G.6
-
120
-
-
33749370142
-
A photoaffinity analogue of discodermolide specifically labels a peptide in beta-tubulin
-
Xia S, Kenesky C S, Rucker P V, Smith III A B, Orr G A, Horwitz S B. A photoaffinity analogue of discodermolide specifically labels a peptide in beta-tubulin. Biochemistry, 45(39) (2006) 11762-75
-
(2006)
Biochemistry
, vol.45
, Issue.39
, pp. 11762-11775
-
-
Xia, S.1
Kenesky, C.S.2
Rucker, P.V.3
Smith III, A.B.4
Orr, G.A.5
Horwitz, S.B.6
-
121
-
-
27544493942
-
Selective effects of the anticancer drug Yondelis (ET-743) on cell-cycle promoters
-
Minuzzo M, Ceribelli M, Pitarque-Marti M, Borrelli S, Erba E, DiSilvio A, Selective effects of the anticancer drug Yondelis (ET-743) on cell-cycle promoters. Mol Pharmacol., 68(5) (2005) 1496-503
-
(2005)
Mol Pharmacol
, vol.68
, Issue.5
, pp. 1496-1503
-
-
Minuzzo, M.1
Ceribelli, M.2
Pitarque-Marti, M.3
Borrelli, S.4
Erba, E.5
Disilvio, A.6
-
122
-
-
23044479629
-
Kahalalide F induces necrosis-like cell death that involves depletion of ErbB3 and inhibition of Akt signaling
-
Janmaat ML, Rodriguez JA, Jimeno J, Kruyt FA, Giaccone G. Kahalalide F induces necrosis-like cell death that involves depletion of ErbB3 and inhibition of Akt signaling. Mol Pharmacol., 68(2) (2005) 502-10
-
(2005)
Mol Pharmacol
, vol.68
, Issue.2
, pp. 502-510
-
-
Janmaat, M.L.1
Rodriguez, J.A.2
Jimeno, J.3
Kruyt, F.A.4
Giaccone, G.5
-
123
-
-
22444444598
-
Inhibition of protein synthesis and activation of stress-activated protein kinases by onnamide A and theopederin B, antitumor marine natural products
-
Lee K H, Nishimura S, Matsunaga S, Fusetani N, Horinouchi S, Yoshida M. Inhibition of protein synthesis and activation of stress-activated protein kinases by onnamide A and theopederin B, antitumor marine natural products. Cancer Sci., 96(6) (2005) 357-64
-
(2005)
Cancer Sci
, vol.96
, Issue.6
, pp. 357-364
-
-
Lee, K.H.1
Nishimura, S.2
Matsunaga, S.3
Fusetani, N.4
Horinouchi, S.5
Yoshida, M.6
-
124
-
-
33751163059
-
Synergistic effects of peloruside A and laulimalide with taxoid site drugs, but not with each other, on tubulin assembly
-
Hamel E, Day B W, Miller J H, Jung M K, Northcote P T, Ghosh A K, Synergistic effects of peloruside A and laulimalide with taxoid site drugs, but not with each other, on tubulin assembly. Mol Pharmacol., 70(5) (2006) 1555-64
-
(2006)
Mol Pharmacol
, vol.70
, Issue.5
, pp. 1555-1564
-
-
Hamel, E.1
Day, B.W.2
Miller, J.H.3
Jung, M.K.4
Northcote, P.T.5
Ghosh, A.K.6
|