-
1
-
-
0035155735
-
Marine pharmacology in 1999: Antitumor and cytotoxic compounds
-
Mayer AMS, Lehmann VKB. Marine pharmacology in 1999: antitumor and cytotoxic compounds. Anticancer Res 2001;21:2489-500.
-
(2001)
Anticancer Res
, vol.21
, pp. 2489-2500
-
-
Mayer, A.M.S.1
Lehmann, V.K.B.2
-
2
-
-
0006500931
-
Marine pharmacology in 1998: Antitumor and cytotoxic compounds
-
Mayer AMS. Marine Pharmacology in 1998: antitumor and cytotoxic compounds. Pharmacologist 1999;41:159-64.
-
(1999)
Pharmacologist
, vol.41
, pp. 159-164
-
-
Mayer, A.M.S.1
-
3
-
-
0033775009
-
A phase I clinical and pharmacokinetic study of the dolastatin analogue cemadotin administered as a 5-day continuous intravenous infusion
-
Supko JG, Lynch TJ, Clark JW, et al. A phase I clinical and pharmacokinetic study of the dolastatin analogue cemadotin administered as a 5-day continuous intravenous infusion. Cancer Chemother Pharmacol 2000;46:319-28.
-
(2000)
Cancer Chemother Pharmacol
, vol.46
, pp. 319-328
-
-
Supko, J.G.1
Lynch, T.J.2
Clark, J.W.3
-
4
-
-
0034629308
-
Induction of apoptosis and inhibition of DNA topoisomerase-I in K-562 cells by a marine microalgal polysaccharide
-
Sogawa K, Yamada T, Sumida T, et al. Induction of apoptosis and inhibition of DNA topoisomerase-I in K-562 cells by a marine microalgal polysaccharide. Life Sci 2000;66:L227-31.
-
(2000)
Life Sci
, vol.66
-
-
Sogawa, K.1
Yamada, T.2
Sumida, T.3
-
5
-
-
0033952076
-
Different microtubule network alterations induced by pachymatismin, a new marine glycoprotein, on two prostatic cell lines
-
Sangrajrang S, Zidane M, Berda P, et al. Different microtubule network alterations induced by pachymatismin, a new marine glycoprotein, on two prostatic cell lines. Cancer Chemother Pharmacol 2000;45:120-6.
-
(2000)
Cancer Chemother Pharmacol
, vol.45
, pp. 120-126
-
-
Sangrajrang, S.1
Zidane, M.2
Berda, P.3
-
6
-
-
0033802875
-
Chronic exposure to bryostatin-1 increases the radiosensitivity of U937 leukaemia cells ectopically expressing Bcl-2 through a non-apoptotic mechanism
-
Cartee L, Davis C, Lin PS, et al. Chronic exposure to bryostatin-1 increases the radiosensitivity of U937 leukaemia cells ectopically expressing Bcl-2 through a non-apoptotic mechanism. Int J Radiat Biol 2000;76:1323-33.
-
(2000)
Int J Radiat Biol
, vol.76
, pp. 1323-1333
-
-
Cartee, L.1
Davis, C.2
Lin, P.S.3
-
7
-
-
0034006706
-
The in vivo effect of bryostatin-1 on paclitaxel-induced tumor growth, mitotic entry, and blood flow
-
Koutcher JA, Motwani M, Zakian KL, et al. The in vivo effect of bryostatin-1 on paclitaxel-induced tumor growth, mitotic entry, and blood flow. Clin Cancer Res 2000;6:1498-507.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1498-1507
-
-
Koutcher, J.A.1
Motwani, M.2
Zakian, K.L.3
-
8
-
-
0034486490
-
The addition of bryostatin 1 to cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) chemotherapy improves response in a CHOP-resistant human diffuse large cell lymphoma xenograft model
-
Mohammad RM, Wall NR, Dutcher JA, et al. The addition of bryostatin 1 to cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) chemotherapy improves response in a CHOP-resistant human diffuse large cell lymphoma xenograft model. Clin Cancer Res 2000;6:4950-6.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4950-4956
-
-
Mohammad, R.M.1
Wall, N.R.2
Dutcher, J.A.3
-
9
-
-
0034254971
-
A phase II trial of bryostatin-1 for patients with metastatic renal cell carcinoma
-
Pagliaro L, Daliani D, Amato R, et al. A phase II trial of bryostatin-1 for patients with metastatic renal cell carcinoma. Cancer 2000;89:615-8.
-
(2000)
Cancer
, vol.89
, pp. 615-618
-
-
Pagliaro, L.1
Daliani, D.2
Amato, R.3
-
10
-
-
12944249449
-
Phase II trial of bryostatin 1 in patients with relapsed low-grade non-Hodgkin's lymphoma and chronic lymphocytic leukemia
-
Varterasian ML, Mohammad RM, Shurafa MS, et al. Phase II trial of bryostatin 1 in patients with relapsed low-grade non-Hodgkin's lymphoma and chronic lymphocytic leukemia. Clin Cancer Res 2000;6:825-8.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 825-828
-
-
Varterasian, M.L.1
Mohammad, R.M.2
Shurafa, M.S.3
-
11
-
-
0034700298
-
Interaction of the anti-tumor compound cryptophycin-52 with tubulin
-
Panda D, Ananthnarayan V, Larson G, et al. Interaction of the anti-tumor compound cryptophycin-52 with tubulin. Biochemistry 2000;39:14121-7.
-
(2000)
Biochemistry
, vol.39
, pp. 14121-14127
-
-
Panda, D.1
Ananthnarayan, V.2
Larson, G.3
-
12
-
-
0033891960
-
Antitumor activity of cryptophycins: Effect of infusion time and combination studies
-
Menon K, Alvarez E, Forler P, et al. Antitumor activity of cryptophycins: effect of infusion time and combination studies. Cancer Chemother Pharmacol 2000;46:142-9.
-
(2000)
Cancer Chemother Pharmacol
, vol.46
, pp. 142-149
-
-
Menon, K.1
Alvarez, E.2
Forler, P.3
-
13
-
-
0033861796
-
Cryptophycin 52 and cryptophycin 55 in sequential and simultaneous combination treatment regimens in human tumor xenografts
-
Teicher BA, Forler P, Menon K, et al. Cryptophycin 52 and cryptophycin 55 in sequential and simultaneous combination treatment regimens in human tumor xenografts. In Vivo 2000;14:471-80.
-
(2000)
In Vivo
, vol.14
, pp. 471-480
-
-
Teicher, B.A.1
Forler, P.2
Menon, K.3
-
14
-
-
0034597581
-
Inhibition of protein synthesis by didemnins: Cell potency and SAR
-
Ahuja D, Geiger A, Ramanjulu JM, et al. Inhibition of protein synthesis by didemnins: cell potency and SAR. J Med Chem 2000;43:4212-8.
-
(2000)
J Med Chem
, vol.43
, pp. 4212-4218
-
-
Ahuja, D.1
Geiger, A.2
Ramanjulu, J.M.3
-
15
-
-
0034445547
-
Phase II trail of didemnin B in previously treated non-Hodgkin's lymphoma: An Eastern Cooperative Oncology Group (ECOG) Study
-
Kucuk O, Young ML, Habermann TM, et al. Phase II trail of didemnin B in previously treated non-Hodgkin's lymphoma: an Eastern Cooperative Oncology Group (ECOG) Study. Am J Clin Oncol 2000;23:273-7.
-
(2000)
Am J Clin Oncol
, vol.23
, pp. 273-277
-
-
Kucuk, O.1
Young, M.L.2
Habermann, T.M.3
-
16
-
-
0033941314
-
Pharmaceutical development of a parenteral lyophilized formulation of the novel antitumor agent aplidine
-
Nuijen B, Bouma M, Henrar RE, et al. Pharmaceutical development of a parenteral lyophilized formulation of the novel antitumor agent aplidine. PDA J Pharm Sci Technol 2000;54:193-208.
-
(2000)
PDA J Pharm Sci Technol
, vol.54
, pp. 193-208
-
-
Nuijen, B.1
Bouma, M.2
Henrar, R.E.3
-
17
-
-
18844469806
-
Taxol and discodermolide represent a synergistic drug combination in human carcinoma cell lines
-
Martello LA, McDaid HM, Regl DL, et al. Taxol and discodermolide represent a synergistic drug combination in human carcinoma cell lines. Clin Cancer Res 2000;6:1978-87.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1978-1987
-
-
Martello, L.A.1
McDaid, H.M.2
Regl, D.L.3
-
18
-
-
0034005620
-
Novel marine-derived anticancer agents: A phase I clinical, pharmacological, and pharmacodynamic study of dolastatin 10 (NSC 376128) in patients with advanced solid tumors
-
Madden T, Tran HT, Beck D, et al. Novel marine-derived anticancer agents: a phase I clinical, pharmacological, and pharmacodynamic study of dolastatin 10 (NSC 376128) in patients with advanced solid tumors. Clin Cancer Res 2000;6:1293-301.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1293-1301
-
-
Madden, T.1
Tran, H.T.2
Beck, D.3
-
19
-
-
0034612352
-
Ecteinascidin 743, a transcription-targeted chemotherapeutic that inhibits MDR1 activation
-
Jin S, Gorfajn B, Faircloth G, et al. Ecteinascidin 743, a transcription-targeted chemotherapeutic that inhibits MDR1 activation. Proc Natl Acad Sci USA 2000;97:6775-9.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 6775-6779
-
-
Jin, S.1
Gorfajn, B.2
Faircloth, G.3
-
20
-
-
0034612344
-
Interference of transcriptional activation by the antineoplastic drug ecteinascidin-743
-
Minuzzo M, Marchini S, Broggini M, et al. Interference of transcriptional activation by the antineoplastic drug ecteinascidin-743. Proc Natl Acad Sci USA 2000;97:6780-4.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 6780-6784
-
-
Minuzzo, M.1
Marchini, S.2
Broggini, M.3
-
21
-
-
0034676314
-
Increased DNA binding specificity for antitumor ecteinascidin 743 through protein DNA interactions?
-
Garcia-Nieto R, Manzanares I, Cuevas C, et al. Increased DNA binding specificity for antitumor ecteinascidin 743 through protein DNA interactions? J Med Chem 2000;43:4367-9.
-
(2000)
J Med Chem
, vol.43
, pp. 4367-4369
-
-
Garcia-Nieto, R.1
Manzanares, I.2
Cuevas, C.3
-
22
-
-
0041082631
-
Bending of DNA upon binding of ecteinascidin 743 and phthalascidin 650 studied by unrestrained molecular dynamics simulations
-
Garcia-Nieto R, Manzanares I, Cuevas C, et al. Bending of DNA upon binding of ecteinascidin 743 and phthalascidin 650 studied by unrestrained molecular dynamics simulations. J Am Chem Soc 2000;122:7172-82.
-
(2000)
J Am Chem Soc
, vol.122
, pp. 7172-7182
-
-
Garcia-Nieto, R.1
Manzanares, I.2
Cuevas, C.3
-
23
-
-
0034490073
-
Pharmacokinetics and pharmacodynamics of the novel marine-derived anticancer agent ecteinascidin 743 in a phase I dose-finding study
-
Van Kesteren C, Cvitkovic E, Taamma A, et al. Pharmacokinetics and pharmacodynamics of the novel marine-derived anticancer agent ecteinascidin 743 in a phase I dose-finding study. Clin Cancer Res 2000;6:4725-32.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4725-4732
-
-
Van Kesteren, C.1
Cvitkovic, E.2
Taamma, A.3
-
24
-
-
0034628224
-
Antimitotic diterpenes from Erythropodium caribaeorum test pharmacophore models for microtubule stabilization
-
Cinel B, Roberge M, Behrisch H, et al. Antimitotic diterpenes from Erythropodium caribaeorum test pharmacophore models for microtubule stabilization. Org Lett 2000;2:257-60.
-
(2000)
Org Lett
, vol.2
, pp. 257-260
-
-
Cinel, B.1
Roberge, M.2
Behrisch, H.3
-
25
-
-
0034665125
-
Cell-based screen for antimitotic agents and identification of analogues of rhizoxin, eleutherobin, and paclitaxel in natural extracts
-
Roberge M, Cinel B, Anderson HJ, et al. Cell-based screen for antimitotic agents and identification of analogues of rhizoxin, eleutherobin, and paclitaxel in natural extracts. Cancer Res 2000;60:5052-8.
-
(2000)
Cancer Res
, vol.60
, pp. 5052-5058
-
-
Roberge, M.1
Cinel, B.2
Anderson, H.J.3
-
26
-
-
0034569844
-
Mechanism of action of aragusterol a (YTA0040), a potent anti-tumor marine steroid targeting the G(1) phase of the cell cycle
-
Fukuoka K, Yamagishi T, Ichihara T, et al. Mechanism of action of aragusterol a (YTA0040), a potent anti-tumor marine steroid targeting the G(1) phase of the cell cycle. Int J Cancer 2000;88:810-9.
-
(2000)
Int J Cancer
, vol.88
, pp. 810-819
-
-
Fukuoka, K.1
Yamagishi, T.2
Ichihara, T.3
-
27
-
-
0034664192
-
Inhibition of topoisomerase II by the marine alkaloid ascididemin and induction of apoptosis in leukemia cells
-
Dassonneville L, Wattez N, Baldeyrou B, et al. Inhibition of topoisomerase II by the marine alkaloid ascididemin and induction of apoptosis in leukemia cells. Biochem Pharmacol 2000;60:527-37.
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 527-537
-
-
Dassonneville, L.1
Wattez, N.2
Baldeyrou, B.3
-
28
-
-
0034603455
-
Mechanism of action studies of cytotoxic marine alkaloids: Ascididemin exhibits thiol-dependent oxidative DNA cleavage
-
Matsumoto SS, Sidford MH, Holden JA, et al. Mechanism of action studies of cytotoxic marine alkaloids: ascididemin exhibits thiol-dependent oxidative DNA cleavage. Tetrahedron Lett 2000;41:1667-70.
-
(2000)
Tetrahedron Lett
, vol.41
, pp. 1667-1670
-
-
Matsumoto, S.S.1
Sidford, M.H.2
Holden, J.A.3
-
29
-
-
0034618674
-
Inhibition of cyclin-dependent kinase 4 (Cdk4) by fascaplysin, a marine natural product
-
Soni R, Muller L, Furet P, et al. Inhibition of cyclin-dependent kinase 4 (Cdk4) by fascaplysin, a marine natural product. Biochem Biophys Res Commun 2000;275:877-84.
-
(2000)
Biochem Biophys Res Commun
, vol.275
, pp. 877-884
-
-
Soni, R.1
Muller, L.2
Furet, P.3
-
30
-
-
0033764523
-
A new indanone from the marine cyanobacterium Lyngbya majuscula that inhibits hypoxia-induced activation of the VEGF promoter in Hep3B cells
-
Nagle DG, Zhou YD, Park PU, et al. A new indanone from the marine cyanobacterium Lyngbya majuscula that inhibits hypoxia-induced activation of the VEGF promoter in Hep3B cells. J Nat Prod 2000;63:1431-3.
-
(2000)
J Nat Prod
, vol.63
, pp. 1431-1433
-
-
Nagle, D.G.1
Zhou, Y.D.2
Park, P.U.3
-
31
-
-
0034092263
-
Isolation, structure determination, and biological activity of lyngbyabellin A from the marine cyanobacterium Lyngbya majuscula
-
Luesch H, Yoshida WY, Moore RE, et al. Isolation, structure determination, and biological activity of lyngbyabellin A from the marine cyanobacterium Lyngbya majuscula. J Nat Prod 2000;63:611-5.
-
(2000)
J Nat Prod
, vol.63
, pp. 611-615
-
-
Luesch, H.1
Yoshida, W.Y.2
Moore, R.E.3
-
32
-
-
0034517207
-
Induction of polyploidization by jaspamide in HL-60 cells
-
Nakazawa H, Kitano K, Cioca DP, et al. Induction of polyploidization by jaspamide in HL-60 cells. Acta Haematol 2000;104:65-71.
-
(2000)
Acta Haematol
, vol.104
, pp. 65-71
-
-
Nakazawa, H.1
Kitano, K.2
Cioca, D.P.3
-
33
-
-
0034708427
-
Melophlins A and B, novel tetramic acids reversing the phenotype of ras-transformed cells, from the marine sponge Melophlus sarassinorum
-
Aoki S, Higuchi K, Ye Y, et al. Melophlins A and B, novel tetramic acids reversing the phenotype of ras-transformed cells, from the marine sponge Melophlus sarassinorum. Tetrahedron 2000;56:1833-6.
-
(2000)
Tetrahedron
, vol.56
, pp. 1833-1836
-
-
Aoki, S.1
Higuchi, K.2
Ye, Y.3
-
34
-
-
0034725101
-
The marine compound spisulosine, an inhibitor of cell proliferation, promotes the disassembly of actin stress fibers
-
Cuadros R, de Garcini EM, Wandosell F, et al. The marine compound spisulosine, an inhibitor of cell proliferation, promotes the disassembly of actin stress fibers. Cancer Lett 2000;152:23-9.
-
(2000)
Cancer Lett
, vol.152
, pp. 23-29
-
-
Cuadros, R.1
De Garcini, E.M.2
Wandosell, F.3
-
35
-
-
0034604641
-
New cytotoxic manzamine alkaloids from a palaun sponge
-
Zhou BN, Slebodnick C, Johnson RK, et al. New cytotoxic manzamine alkaloids from a palaun sponge. Tetrahedron 2000;56:5781-4.
-
(2000)
Tetrahedron
, vol.56
, pp. 5781-5784
-
-
Zhou, B.N.1
Slebodnick, C.2
Johnson, R.K.3
-
36
-
-
0034612972
-
Ma'edamines A and B, cytotoxic bromotyrosine alkaloids with a unique 2(IH)pyrazinone ring from sponge Suberea sp.
-
Hirano K, Kubota T, Tsuda M, et al. Ma'edamines A and B, cytotoxic bromotyrosine alkaloids with a unique 2(IH)pyrazinone ring from sponge Suberea sp. Tetrahedron 2000;56:8107-10.
-
(2000)
Tetrahedron
, vol.56
, pp. 8107-8110
-
-
Hirano, K.1
Kubota, T.2
Tsuda, M.3
-
37
-
-
0034692370
-
Chondropsins A and B: Novel tumor cell growth-inhibitory macrolide lactams from the marine sponge Chondropsis sp.
-
Cantrell CL, Gustafson KR, Cecere MR, et al. Chondropsins A and B: novel tumor cell growth-inhibitory macrolide lactams from the marine sponge Chondropsis sp. J Am Chem Soc 2000;122:8825-9.
-
(2000)
J Am Chem Soc
, vol.122
, pp. 8825-8829
-
-
Cantrell, C.L.1
Gustafson, K.R.2
Cecere, M.R.3
-
38
-
-
0033945101
-
Antineoplastic agents 430: Isolation and structure of cribrostatins 3, 4, and 5 from the Republic of Maldives Cribrochalina species
-
Pettit GR, Knight JC, Collins JC, et al. Antineoplastic agents 430: isolation and structure of cribrostatins 3, 4, and 5 from the Republic of Maldives Cribrochalina species. J Nat Prod 2000;63:793-8.
-
(2000)
J Nat Prod
, vol.63
, pp. 793-798
-
-
Pettit, G.R.1
Knight, J.C.2
Collins, J.C.3
-
39
-
-
17544379500
-
Haligramides A and B, two new cytotoxic hexapeptides from the marine sponge Haliclona nigra
-
Rashid MA, Gustafson KR, Boswell JL, et al. Haligramides A and B, two new cytotoxic hexapeptides from the marine sponge Haliclona nigra. J Nat Prod 2000;63:956-9.
-
(2000)
J Nat Prod
, vol.63
, pp. 956-959
-
-
Rashid, M.A.1
Gustafson, K.R.2
Boswell, J.L.3
-
40
-
-
0034637608
-
Mangicols: Structures and biosynthesis of A new class of sesterterpene polyols from a marine fungus of the genus Fusarium
-
Renner MK, Jensen PR, Fenical W. Mangicols: structures and biosynthesis of A new class of sesterterpene polyols from a marine fungus of the genus Fusarium. J Org Chem 2000;65:4843-52.
-
(2000)
J Org Chem
, vol.65
, pp. 4843-4852
-
-
Renner, M.K.1
Jensen, P.R.2
Fenical, W.3
-
41
-
-
0034739423
-
N-methylsansalvamide, a cytotoxic cyclic depsipeptide from a marine fungus of the genus Fusarium
-
Cueto M, Jensen PR, Fenical W. N-methylsansalvamide, a cytotoxic cyclic depsipeptide from a marine fungus of the genus Fusarium. Phytochemistry 2000;55:223-6.
-
(2000)
Phytochemistry
, vol.55
, pp. 223-226
-
-
Cueto, M.1
Jensen, P.R.2
Fenical, W.3
-
42
-
-
0034719903
-
Neomarinone, and new cytotoxic marinone derivatives, produced by a marine filamentous bacterium (actinomycetales)
-
Hardt IH, Jensen PR, Fenical W. Neomarinone, and new cytotoxic marinone derivatives, produced by a marine filamentous bacterium (actinomycetales). Tetrahedron Lett 2000;41:2073-6.
-
(2000)
Tetrahedron Lett
, vol.41
, pp. 2073-2076
-
-
Hardt, I.H.1
Jensen, P.R.2
Fenical, W.3
-
43
-
-
0033635276
-
Pharmaceutical development of anticancer agents derived from marine sources
-
Nuijen B, Bouma M, Manada C, et al. Pharmaceutical development of anticancer agents derived from marine sources. Anti-Cancer Drugs 2000;11:793-811.
-
(2000)
Anti-Cancer Drugs
, vol.11
, pp. 793-811
-
-
Nuijen, B.1
Bouma, M.2
Manada, C.3
-
44
-
-
17544372748
-
Novel bioactive sulfated alkene and alkanes from the mediterranean ascidian Halocynthia papillosa
-
Aiello A, Carbonelli S, Esposito G, et al. Novel bioactive sulfated alkene and alkanes from the mediterranean ascidian Halocynthia papillosa. J Nat Prod 2000;63:1590-2.
-
(2000)
J Nat Prod
, vol.63
, pp. 1590-1592
-
-
Aiello, A.1
Carbonelli, S.2
Esposito, G.3
-
45
-
-
0034700812
-
Amaminols A and B, new bicyclic amino alcohols from an unidentified tunicate of the family Polyclinidae
-
Sata NU, Fusetani N. Amaminols A and B, new bicyclic amino alcohols from an unidentified tunicate of the family Polyclinidae. Tetrahedron Lett 2000;41:489-92.
-
(2000)
Tetrahedron Lett
, vol.41
, pp. 489-492
-
-
Sata, N.U.1
Fusetani, N.2
-
46
-
-
0034629561
-
Amphidinolide T. novel 19-membered macrolide from marine dinoflagellate Amphidinium sp.
-
Tsuda M, Endo T, Kobayashi J. Amphidinolide T, novel 19-membered macrolide from marine dinoflagellate Amphidinium sp. J Org Chem 2000;65:1349-52.
-
(2000)
J Org Chem
, vol.65
, pp. 1349-1352
-
-
Tsuda, M.1
Endo, T.2
Kobayashi, J.3
-
47
-
-
0034728137
-
Amphidinolide novel 14-membered macrolide from marine dinoflagellate Amphidinium sp.
-
Kubota T, Tsuda M, Kobayashi J. Amphidinolide V, novel 14-membered macrolide from marine dinoflagellate Amphidinium sp. Tetrahedron Lett 2000;41:713-6.
-
(2000)
Tetrahedron Lett
, vol.41
, pp. 713-716
-
-
Kubota, T.1
Tsuda, M.2
Kobayashi J. V3
-
48
-
-
0034701596
-
New cytotoxic isomalabaricane-type sesterterpenes from the New Caledonian marine sponge Rhabdastrella globostellata
-
Bourguet-Kondracki ML, Longeon A, Debitus C, et al. New cytotoxic isomalabaricane-type sesterterpenes from the New Caledonian marine sponge Rhabdastrella globostellata. Tetrahedron Lett 2000;41:3087-90.
-
(2000)
Tetrahedron Lett
, vol.41
, pp. 3087-3090
-
-
Bourguet-Kondracki, M.L.1
Longeon, A.2
Debitus, C.3
-
49
-
-
0034716543
-
Brassicolene, a novel cytotoxic diterpenoid from the Formosan soft coral Nephthea brassica
-
Duh CY, Wang SK, Weng YL. Brassicolene, a novel cytotoxic diterpenoid from the Formosan soft coral Nephthea brassica. Tetrahedron Lett 2000;41:1401-3.
-
(2000)
Tetrahedron Lett
, vol.41
, pp. 1401-1403
-
-
Duh, C.Y.1
Wang, S.K.2
Weng, Y.L.3
-
50
-
-
0033976362
-
Triterpene glycosides from the Far-Eastern sea cucumber Pentamera calcigera: 1, Monosulfated glycosides and cytotoxicity of their unsulfated derivatives
-
Avilov SA, Antonov AS, Drozdova OA, et al. Triterpene glycosides from the Far-Eastern sea cucumber Pentamera calcigera: 1, monosulfated glycosides and cytotoxicity of their unsulfated derivatives. J Nat Prod 2000;63:65-71.
-
(2000)
J Nat Prod
, vol.63
, pp. 65-71
-
-
Avilov, S.A.1
Antonov, A.S.2
Drozdova, O.A.3
-
51
-
-
0033791279
-
Colopsinols D and E, new polyhydroxyl linear carbon chain compounds from marine dinoflagellate Amphidinium sp.
-
Kubota T, Tsuda M, Takahashi M, et al. Colopsinols D and E, new polyhydroxyl linear carbon chain compounds from marine dinoflagellate Amphidinium sp. Chem Pharm Bull (Tokyo) 2000;48:1447-51.
-
(2000)
Chem Pharm Bull (Tokyo)
, vol.48
, pp. 1447-1451
-
-
Kubota, T.1
Tsuda, M.2
Takahashi, M.3
-
52
-
-
0034526129
-
Cytotoxic cembrenolides and steroids from the formosan soft coral Sarcophyton crassocaule
-
Duh CY, Wang SK, Chung SG, et al. Cytotoxic cembrenolides and steroids from the formosan soft coral Sarcophyton crassocaule. J Nat Prod 2000;63:1634-7.
-
(2000)
J Nat Prod
, vol.63
, pp. 1634-1637
-
-
Duh, C.Y.1
Wang, S.K.2
Chung, S.G.3
-
53
-
-
0033917818
-
Cytotoxic cembrenolide diterpenes from the formosan soft coral Lobophytum crassum
-
Duh CY, Wang SK, Huang BT, et al. Cytotoxic cembrenolide diterpenes from the formosan soft coral Lobophytum crassum. J Nat Prod 2000;63:884-5.
-
(2000)
J Nat Prod
, vol.63
, pp. 884-885
-
-
Duh, C.Y.1
Wang, S.K.2
Huang, B.T.3
-
54
-
-
0034080628
-
Hachijodines A-G: Seven new cytotoxic 3-alkylpyridine alkaloids from two marine sponges of the genera Xestospongia and Amphimedon
-
Tsukamoto S, Takahashi M, Matsunaga S, et al. Hachijodines A-G: seven new cytotoxic 3-alkylpyridine alkaloids from two marine sponges of the genera Xestospongia and Amphimedon. J Nat Prod 2000;63:682-4.
-
(2000)
J Nat Prod
, vol.63
, pp. 682-684
-
-
Tsukamoto, S.1
Takahashi, M.2
Matsunaga, S.3
-
55
-
-
0033952825
-
Chemistry of sponges: 19, Novel bioactive metabolites from Hamigera tarangaensis
-
Wellington KD, Cambie RC, Rutledge PS, et al. Chemistry of sponges: 19, novel bioactive metabolites from Hamigera tarangaensis. J Nat Prod 2000;63:79-85.
-
(2000)
J Nat Prod
, vol.63
, pp. 79-85
-
-
Wellington, K.D.1
Cambie, R.C.2
Rutledge, P.S.3
-
56
-
-
0001177687
-
Hermitamides A and B, toxic malyngamide-type natural products from the marine cyanobacterium Lyngbya majuscula
-
Tan LT, Okino T, Gerwick WH. Hermitamides A and B, toxic malyngamide-type natural products from the marine cyanobacterium Lyngbya majuscula. J Nat Prod 2000;63:952-5.
-
(2000)
J Nat Prod
, vol.63
, pp. 952-955
-
-
Tan, L.T.1
Okino, T.2
Gerwick, W.H.3
-
57
-
-
0034693342
-
Honulactones: New bishomoscalarane sesterterpenes from the Indonesian sponge Strepsichordaia aliena
-
Jimenez JI, Yoshida WY, Scheuer PJ, et al. Honulactones: new bishomoscalarane sesterterpenes from the Indonesian sponge Strepsichordaia aliena. J Org Chem 2000;65:6837-40.
-
(2000)
J Org Chem
, vol.65
, pp. 6837-6840
-
-
Jimenez, J.I.1
Yoshida, W.Y.2
Scheuer, P.J.3
-
58
-
-
0343238270
-
IB-96212, a novel cytotoxic macrolide produced by a marine Micromonospora: I, taxonomy, fermentation, isolation and biological activities
-
Fernandez-Chimeno RI, Canedo L, Espliego F, et al. IB-96212, a novel cytotoxic macrolide produced by a marine Micromonospora: I, taxonomy, fermentation, isolation and biological activities. J Antibiot (Tokyo) 2000;53:474-8.
-
(2000)
J Antibiot (Tokyo)
, vol.53
, pp. 474-478
-
-
Fernandez-Chimeno, R.I.1
Canedo, L.2
Espliego, F.3
-
59
-
-
0033921415
-
A cytotoxic lobane diterpene from the formosan soft coral Sinularia inelegans
-
Chai MC, Wang SK, Dai CF, et al. A cytotoxic lobane diterpene from the formosan soft coral Sinularia inelegans. J Nat Prod 2000;63:843-4.
-
(2000)
J Nat Prod
, vol.63
, pp. 843-844
-
-
Chai, M.C.1
Wang, S.K.2
Dai, C.F.3
-
60
-
-
0034622873
-
A new antitumor isoquinoline alkaloid from the marine nudibranch Jorunna funebris
-
Fontana A, Cavaliere P, Wahidulla S, et al. A new antitumor isoquinoline alkaloid from the marine nudibranch Jorunna funebris. Tetrahedron 2000;56:7305-8.
-
(2000)
Tetrahedron
, vol.56
, pp. 7305-7308
-
-
Fontana, A.1
Cavaliere, P.2
Wahidulla, S.3
-
61
-
-
0033753789
-
Malyngamides O and P from the sea hare Stylocheilus longicauda
-
Gallimore WA, Scheuer PJ. Malyngamides O and P from the sea hare Stylocheilus longicauda. J Nat Prod 2000;63:1422-4.
-
(2000)
J Nat Prod
, vol.63
, pp. 1422-1424
-
-
Gallimore, W.A.1
Scheuer, P.J.2
-
62
-
-
17544377633
-
Matemone, a new bioactive bromine-containing oxindole alkaloid from the Indian Ocean sponge lotrochota purpurea
-
Carletti I, Banaigs B, Amade P. Matemone, a new bioactive bromine-containing oxindole alkaloid from the Indian Ocean sponge lotrochota purpurea. J Nat Prod 2000;63:981-3.
-
(2000)
J Nat Prod
, vol.63
, pp. 981-983
-
-
Carletti, I.1
Banaigs, B.2
Amade, P.3
-
63
-
-
0033806562
-
Microcyclamide, a cytotoxic cyclic hexapeptide from the cyanobacterium Microcystis aeruginosa
-
Ishida K, Nakagawa H, Murakami M. Microcyclamide, a cytotoxic cyclic hexapeptide from the cyanobacterium Microcystis aeruginosa. J Nat Prod 2000;63:1315-7.
-
(2000)
J Nat Prod
, vol.63
, pp. 1315-1317
-
-
Ishida, K.1
Nakagawa, H.2
Murakami, M.3
-
64
-
-
0034595622
-
Microsclerodermins F-I, antitumor and antifungal cyclic peptides from the lithistid sponge Microscleroderma sp.
-
Qureshi A, Colin PL, Faulkner DJ. Microsclerodermins F-I, antitumor and antifungal cyclic peptides from the lithistid sponge Microscleroderma sp. Tetrahedron 2000;56:3679-85.
-
(2000)
Tetrahedron
, vol.56
, pp. 3679-3685
-
-
Qureshi, A.1
Colin, P.L.2
Faulkner, D.J.3
-
65
-
-
0034045487
-
Mycalamides C and D, cytotoxic compounds from the marine sponge Stylinos species
-
Simpson JS, Garson MJ, Blunt JW, et al. Mycalamides C and D, cytotoxic compounds from the marine sponge Stylinos species. J Nat Prod 2000;63:704-6.
-
(2000)
J Nat Prod
, vol.63
, pp. 704-706
-
-
Simpson, J.S.1
Garson, M.J.2
Blunt, J.W.3
-
66
-
-
0034092265
-
Mycalamide D, a new cytotoxic amide from the New Zealand marine sponge Mycale species
-
West LM, Northcote PT, Hood KA, et al. Mycalamide D, a new cytotoxic amide from the New Zealand marine sponge Mycale species. J Nat Prod 2000;63:707-9.
-
(2000)
J Nat Prod
, vol.63
, pp. 707-709
-
-
West, L.M.1
Northcote, P.T.2
Hood, K.A.3
-
67
-
-
0034634633
-
New diterpenoids from the octocoral Pachyclavularia violacea collected in Papua New Guinea
-
Xu L, Patrick BO, Roberge M, et al. New diterpenoids from the octocoral Pachyclavularia violacea collected in Papua New Guinea. Tetrahedron 2000;56:9031-7.
-
(2000)
Tetrahedron
, vol.56
, pp. 9031-9037
-
-
Xu, L.1
Patrick, B.O.2
Roberge, M.3
-
68
-
-
0033776514
-
Pellynol I, a new cytotoxic polyacetylene from the sponge Pellina sp.
-
Rashid MA, Gustafson KR, Boyd MR. Pellynol I, a new cytotoxic polyacetylene from the sponge Pellina sp. J Nat Prod 2000;14:387-92.
-
(2000)
J Nat Prod
, vol.14
, pp. 387-392
-
-
Rashid, M.A.1
Gustafson, K.R.2
Boyd, M.R.3
-
69
-
-
0034723214
-
Peloruside A: A potent cytotoxic macrolide isolated from the New Zealand marine sponge Mycale sp.
-
West LM, Northcote PT, Battershill CN. Peloruside A: a potent cytotoxic macrolide isolated from the New Zealand marine sponge Mycale sp. J Org Chem 2000;65:445-9.
-
(2000)
J Org Chem
, vol.65
, pp. 445-449
-
-
West, L.M.1
Northcote, P.T.2
Battershill, C.N.3
-
70
-
-
0034730648
-
Metabolites from the sponge Plakortis simplex: 3, Isolation and stereostructure of novel bioactive cycloperoxides and diol analogues
-
Fattorusso E, Taglialatela-Scafati O, Di Rosa M, et al. Metabolites from the sponge Plakortis simplex: 3, isolation and stereostructure of novel bioactive cycloperoxides and diol analogues. Tetrahedron 2000;56:7959-67.
-
(2000)
Tetrahedron
, vol.56
, pp. 7959-7967
-
-
Fattorusso, E.1
Taglialatela-Scafati, O.2
Di Rosa, M.3
-
71
-
-
0033914530
-
Pyrinodemins B-D, potent cytotoxic bis-pyridine alkaloids from marine sponge Amphimedon sp.
-
Hirano K, Kubota T, Tsuda M, et al. Pyrinodemins B-D, potent cytotoxic bis-pyridine alkaloids from marine sponge Amphimedon sp. Chem Pharm Bull (Tokyo) 2000;48:974-7.
-
(2000)
Chem Pharm Bull (Tokyo)
, vol.48
, pp. 974-977
-
-
Hirano, K.1
Kubota, T.2
Tsuda, M.3
-
72
-
-
0033753806
-
New cytotoxic sterol glycosides from the octocoral Carijoa (Telesto) riisei
-
Maia LF, Epifanio RA, Fenical W. New cytotoxic sterol glycosides from the octocoral Carijoa (Telesto) riisei. J Nat Prod 2000;63:1427-30.
-
(2000)
J Nat Prod
, vol.63
, pp. 1427-1430
-
-
Maia, L.F.1
Epifanio, R.A.2
Fenical, W.3
-
73
-
-
0034609141
-
New antiproliferative epoxysecosterols from Pseudopterogorgia americana
-
Naz S, Kerr RG, Narayanan R. New antiproliferative epoxysecosterols from Pseudopterogorgia americana. Tetrahedron Lett 2000;41:6035-40.
-
(2000)
Tetrahedron Lett
, vol.41
, pp. 6035-6040
-
-
Naz, S.1
Kerr, R.G.2
Narayanan, R.3
-
74
-
-
0033780101
-
4′-N-methyl-5′-hydroxy-staurosporine and 5′-hydroxystaurosporine, new indolocarbazole alkaloids from a marine Micromonospora sp. strain
-
Hernandez LM, Blanco JA, Baz JP, et al. 4′-N-methyl-5′-hydroxy-staurosporine and 5′-hydroxystaurosporine, new indolocarbazole alkaloids from a marine Micromonospora sp. strain. J Antibiot (Tokyo) 2000;53:895-902.
-
(2000)
J Antibiot (Tokyo)
, vol.53
, pp. 895-902
-
-
Hernandez, L.M.1
Blanco, J.A.2
Baz, J.P.3
-
75
-
-
0342614927
-
New isomalabaricane triterpenes from the marine sponge Stelletta globostellata that induce morphological changes in rat fibroblasts
-
Oku N, Matsunaga S, Wada S, et al. New isomalabaricane triterpenes from the marine sponge Stelletta globostellata that induce morphological changes in rat fibroblasts. J Nat Prod 2000;63:205-9.
-
(2000)
J Nat Prod
, vol.63
, pp. 205-209
-
-
Oku, N.1
Matsunaga, S.2
Wada, S.3
-
76
-
-
0034690799
-
New bioactive steroids from the Gorgonian Acalycigorgia Inermis
-
Rho J. New bioactive steroids from the Gorgonian Acalycigorgia Inermis. Bull Korean Chem Soc 2000;21:518-20.
-
(2000)
Bull Korean Chem Soc
, vol.21
, pp. 518-520
-
-
Rho, J.1
-
77
-
-
0033621674
-
A cytotoxic 5alpha,8alpha-epidioxy-sterol from a soft coral Sinularia species
-
Sheu JH, Chang KC, Duh CY. A cytotoxic 5alpha,8alpha-epidioxy-sterol from a soft coral Sinularia species. J Nat Prod 2000;63:149-51.
-
(2000)
J Nat Prod
, vol.63
, pp. 149-151
-
-
Sheu, J.H.1
Chang, K.C.2
Duh, C.Y.3
-
78
-
-
0033842160
-
Isolation of bioactive 5 alpha,8 alpha-epidioxy sterols from the marine sponge Luffariella cf. variabilis
-
Gauvin A, Smadja J, Aknin M, et al. Isolation of bioactive 5 alpha,8 alpha-epidioxy sterols from the marine sponge Luffariella cf. variabilis. Can J Chem 2000;78:986-92.
-
(2000)
Can J Chem
, vol.78
, pp. 986-992
-
-
Gauvin, A.1
Smadja, J.2
Aknin, M.3
-
79
-
-
0033989478
-
Isolation and structure elucidation of new cytotoxic steroids from the gorgonian Leptogorgia sarmentosa
-
Garrido L, Zubia E, Ortega MJ, et al. Isolation and structure elucidation of new cytotoxic steroids from the gorgonian Leptogorgia sarmentosa. Steroids 2000;65:85-8.
-
(2000)
Steroids
, vol.65
, pp. 85-88
-
-
Garrido, L.1
Zubia, E.2
Ortega, M.J.3
-
80
-
-
0034693489
-
16Beta-hydroxy-5alpha-cholestane-3,6-dione, a novel cytotoxic oxysterol from the red alga Jania rubens
-
Ktari L, Blond A, Guyot M. 16Beta-hydroxy-5alpha-cholestane-3,6-dione, a novel cytotoxic oxysterol from the red alga Jania rubens. Bioorg Med Chem Lett 2000;10:2563-5.
-
(2000)
Bioorg Med Chem Lett
, vol.10
, pp. 2563-2565
-
-
Ktari, L.1
Blond, A.2
Guyot, M.3
-
81
-
-
0033623905
-
7Alpha-hydroxytheonellasterol, a cytotoxic 4-methylene sterol from the Philippines sponge Theonella swinhoei
-
Qureshi A, Faulkner DJ. 7alpha-hydroxytheonellasterol, a cytotoxic 4-methylene sterol from the Philippines sponge Theonella swinhoei. J Nat Prod 2000;63:841-2.
-
(2000)
J Nat Prod
, vol.63
, pp. 841-842
-
-
Qureshi, A.1
Faulkner, D.J.2
-
82
-
-
0033760037
-
Stolonic acids A and B, new cytotoxic cyclic peroxides from an Indian Ocean ascidian Stolonica species
-
Davies-Coleman MT, Gustafson KR, Cantrell CL, et al. Stolonic acids A and B, new cytotoxic cyclic peroxides from an Indian Ocean ascidian Stolonica species. J Nat Prod 2000;63:1411-3.
-
(2000)
J Nat Prod
, vol.63
, pp. 1411-1413
-
-
Davies-Coleman, M.T.1
Gustafson, K.R.2
Cantrell, C.L.3
-
83
-
-
0034637454
-
Minor metabolites from the ascidian Stolonica socialis and cytotoxicity of stolonoxides
-
Duran R, Zubia E, Ortega MJ, et al. Minor metabolites from the ascidian Stolonica socialis and cytotoxicity of stolonoxides. Tetrahedron 2000;56:6031-7.
-
(2000)
Tetrahedron
, vol.56
, pp. 6031-6037
-
-
Duran, R.1
Zubia, E.2
Ortega, M.J.3
-
84
-
-
0034716024
-
Strongylodiols A, B and C, new cytotoxic acetylenic alcohols isolated from the Okinawan marine sponge of the genus Strongylophora as each enantiomeric mixture with a different ratio
-
Watanabe K, Tsuda Y, Yamane Y, et al. Strongylodiols A, B and C, new cytotoxic acetylenic alcohols isolated from the Okinawan marine sponge of the genus Strongylophora as each enantiomeric mixture with a different ratio. Tetrahedron Lett 2000;41:9271-6.
-
(2000)
Tetrahedron Lett
, vol.41
, pp. 9271-9276
-
-
Watanabe, K.1
Tsuda, Y.2
Yamane, Y.3
-
85
-
-
0034013012
-
Sulcatin, a novel antiproliferative N-methylpyridinium alkaloid from the ascidian Microcosmus vulgaris
-
Aiello A, Fattorusso E, Menna M, et al. Sulcatin, a novel antiproliferative N-methylpyridinium alkaloid from the ascidian Microcosmus vulgaris. J Nat Prod 2000;63:517-9.
-
(2000)
J Nat Prod
, vol.63
, pp. 517-519
-
-
Aiello, A.1
Fattorusso, E.2
Menna, M.3
-
86
-
-
0033961890
-
Tamandarins A and B: New cytotoxic depsipeptides from a brazilian ascidian of the family didemnidae
-
Vervoort H, Fenical W, Epifanio RA. Tamandarins A and B: new cytotoxic depsipeptides from a brazilian ascidian of the family didemnidae. J Org Chem 2000;65:782-92.
-
(2000)
J Org Chem
, vol.65
, pp. 782-792
-
-
Vervoort, H.1
Fenical, W.2
Epifanio, R.A.3
-
87
-
-
0033998276
-
A new bioactive triene aldehyde from the marine sponge Leucetta microraphis
-
Watanabe K, Tsuda Y, Iwashima M, et al. A new bioactive triene aldehyde from the marine sponge Leucetta microraphis. J Nat Prod 2000;63:258-60.
-
(2000)
J Nat Prod
, vol.63
, pp. 258-260
-
-
Watanabe, K.1
Tsuda, Y.2
Iwashima, M.3
|