Kahalalide K: A new cyclic depsipeptide from the Hawaiian green alga Bryopsis species

Journal of Natural Products

Volumn 62, Issue 8, 1999, Pages 1169-1172

  Kan, Yukiko ^a   Fujita, Tsuyoshi ^a   Sakamoto, Bryan ^b   Hokama, Yoshitsugi ^b   Nagai, Hiroshi ^a  

^a SUNTORY INSTITUTE FOR BIOORGANIC RESEARCH   (Japan)

^b UNIVERSITY OF HAWAII   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CYCLODEPSIPEPTIDE; KAHALALIDE K; UNCLASSIFIED DRUG;

ARTICLE; GREEN ALGA; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PROTON NUCLEAR MAGNETIC RESONANCE; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STEREOCHEMISTRY;

BRYOPSIS;

EID: 0032822307     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np990053y     Document Type: Article

References (17)

1. Hamann, M. T.; Scheuer, P. J. J. Am. Chem. Soc. 1993, 115, 5825-5826.
2. Hamann, M. T.; Otto, C. S.; Scheuer, P. J.; Dunbar, D. C. J. Org. Chem. 1996, 61, 6594-6600.
3. Goetz, G.; Nakao, Y.; Scheuer, P. J. J. Nat. Prod. 1997, 60, 562-567.
4. Willker, W.; Leibfritz, D.; Kerssebaum, R.; Bermel, W. Magn. Reson. Chem. 1993, 31, 287-292.
5. Shoji, J.; Kato, T.; Sagazaki, R. J. Antibiot. 1976, 29, 1268-1274; Shoji, J.; Kato, T. J. Antibiot. 1976, 29, 1275-1280; Shoji, J.; Kato, T.; Matsumoto, K.; Takahashi, Y.; Mayama, M. J. Antibiot. 1976, 29, 1281-1285.
6. Shoji, J.; Kato, T.; Sagazaki, R. J. Antibiot. 1976, 29, 1268-1274; Shoji, J.; Kato, T. J. Antibiot. 1976, 29, 1275-1280; Shoji, J.; Kato, T.; Matsumoto, K.; Takahashi, Y.; Mayama, M. J. Antibiot. 1976, 29, 1281-1285.
7. Shoji, J.; Kato, T.; Sagazaki, R. J. Antibiot. 1976, 29, 1268-1274; Shoji, J.; Kato, T. J. Antibiot. 1976, 29, 1275-1280; Shoji, J.; Kato, T.; Matsumoto, K.; Takahashi, Y.; Mayama, M. J. Antibiot. 1976, 29, 1281-1285.
8. Rietschel, E. T.; Luderitz, O.; Volk, W. A. J. Bacteriol. 1975, 122, 1180-1188.
9. Biemann, K. In Methods in Enzymology; McCloskey, J. A., Ed. Academic: New York, Vol. 193; pp 886-887.
10. Marfey, P. Carlsberg Res. Commun. 1984, 49, 591-596.
11. Kahalalides A and B (100 μg/mL) showed no cytotoxic effects on mouse neuroblastoma cells (CCL131). Kahalalides A and B (100 μg/mL) displayed no changes in growth or morphology of G. toxicus. The bioactivity of kahalalide G was not examined in this study.
12. Yasumoto, T.; Murata, M. Chem. Rev. 1993, 93, 1897-1909.
13. Shimizu, Y.; Shimizu, H.; Scheuer, P. J.; Hokama, Y.; Oyama, M.; Miyahara, J. T. Bull. Chem. Soc. Sci. Fish. 1982, 48, 811-813.
14. Sakamoto, B.; Hokama, Y.; Kan, Y.; Nagai, H. Submitted for publication.
15. Nagai, H.; Sakamoto, B. Unpublished observations.
16. Reese, M. T.; Gulavita, N. K.; Nakao, Y.; Hamann, M. T.; Yoshida, W. Y.; Coval, S. J.; Scheuer, P. J. J. Am. Chem. Soc. 1998, 118, 1181-1184.
17. Nakao, Y.; Yoshida, W. Y.; Szabo, C. M.; Baker, B. J.; Scheuer, P. J. J. Org. Chem. 1998, 63, 3272-3280.