Marine sponge-derived polymeric alkylpyridinium salts as a novel tumor chemotherapeutic targeting the cholinergic system in lung tumors

International Journal of Oncology

Volumn 29, Issue 6, 2006, Pages 1381-1388

  Paleari, Laura ^a   Trombino, Sonya ^b   Falugi, Carla ^b   Gallus, Lorenzo ^b   Carlone, Sebastiano ^a   Angelini, Cristiano ^b   Sepcic, Kristina ^c   Turk, Tom ^c   Faimali, Marco ^d   Noonan, Douglas M ^e   Albini, Adriana ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c UNIVERSITY OF LJUBLJANA   (Slovenia)

^d CNR   (Italy)

^e UNIVERSITY OF INSUBRIA   (Italy)

Author keywords

Alkylpyridinium salts; Cholinergic system; Lung tumors; Marine sponge

Indexed keywords

CHOLINESTERASE INHIBITOR; POLY APS; POLY-APS; POLYMER; PYRIDINIUM DERIVATIVE; VESICULAR ACETYLCHOLINE TRANSPORTER;

ADENOCARCINOMA; ANIMAL; APOPTOSIS; ARTICLE; C57BL MOUSE; CELL COMMUNICATION; CHEMISTRY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; HUMAN; ISOLATION AND PURIFICATION; LUNG NON SMALL CELL CANCER; LUNG TUMOR; METABOLISM; MOUSE; PATHOLOGY; SPONGE (PORIFERA);

ADENOCARCINOMA, CLEAR CELL; ANIMALS; APOPTOSIS; CARCINOMA, NON-SMALL-CELL LUNG; CELL COMMUNICATION; CHOLINESTERASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; LUNG NEOPLASMS; MICE; MICE, INBRED C57BL; POLYMERS; PORIFERA; PYRIDINIUM COMPOUNDS; VESICULAR ACETYLCHOLINE TRANSPORT PROTEINS;

EID: 37749006846     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.29.6.1381     Document Type: Article

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