메뉴 건너뛰기




Volumn 120, Issue 6, 2012, Pages 1237-1245

Migratory, and not lymphoid-resident, dendritic cells maintain peripheral self-tolerance and prevent autoimmunity via induction of iTreg cells

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; GAMMA INTERFERON; GLYCOPROTEIN P 15095; HERMES ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA; MACROPHAGE DERIVED CHEMOKINE;

EID: 84865277279     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-09-379776     Document Type: Article
Times cited : (70)

References (53)
  • 1
    • 20444485767 scopus 로고    scopus 로고
    • Cellular and genetic mechanisms of self tolerance and autoimmunity
    • DOI 10.1038/nature03724
    • Goodnow CC, Sprent J, Fazekas de St Groth B, Vinuesa CG. Cellular and genetic mechanisms of self tolerance and autoimmunity. Nature. 2005;435(7042):590-597. (Pubitemid 40825498)
    • (2005) Nature , vol.435 , Issue.7042 , pp. 590-597
    • Goodnow, C.C.1    Sprent, J.2    De St., G.B.F.3    Vinuesa, C.G.4
  • 2
    • 2442567829 scopus 로고    scopus 로고
    • Back to central tolerance
    • DOI 10.1016/S1074-7613(04)00111-6, PII S1074761304001116
    • Mathis D, Benoist C. Back to central tolerance. Immunity. 2004;20(5):509-516. (Pubitemid 38638121)
    • (2004) Immunity , vol.20 , Issue.5 , pp. 509-516
    • Mathis, D.1    Benoist, C.2
  • 3
    • 70349231487 scopus 로고    scopus 로고
    • Induction of peripheral CD4+ T-cell tolerance and CD8+ T-cell cross-tolerance by dendritic cells
    • Lutz MB, Kurts C. Induction of peripheral CD4+ T-cell tolerance and CD8+ T-cell cross-tolerance by dendritic cells. Eur J Immunol. 2009;39(9):2325-2330.
    • (2009) Eur J Immunol , vol.39 , Issue.9 , pp. 2325-2330
    • Lutz, M.B.1    Kurts, C.2
  • 5
    • 74049164847 scopus 로고    scopus 로고
    • Regulatory T cells exert checks and balances on self tolerance and autoimmunity
    • Wing K, Sakaguchi S. Regulatory T cells exert checks and balances on self tolerance and autoimmunity. Nat Immunol. 2010;11(1):7-13.
    • (2010) Nat Immunol , vol.11 , Issue.1 , pp. 7-13
    • Wing, K.1    Sakaguchi, S.2
  • 6
    • 29244435493 scopus 로고    scopus 로고
    • Inducing and expanding regulatory T cell populations by foreign antigen
    • DOI 10.1038/ni1265, PII N1265
    • Kretschmer K, Apostolou I, Hawiger D, Khazaie K, Nussenzweig MC, von Boehmer H. Inducing and expanding regulatory T-cell populations by foreign antigen. Nat Immunol. 2005;6(12):1219-1227. (Pubitemid 43045633)
    • (2005) Nature Immunology , vol.6 , Issue.12 , pp. 1219-1227
    • Kretschmer, K.1    Apostolou, I.2    Hawiger, D.3    Khazaie, K.4    Nussenzweig, M.C.5    Von, B.H.6
  • 7
    • 51349095960 scopus 로고    scopus 로고
    • Tuning microenvironments: Induction of regulatory T cells by dendritic cells
    • Belkaid Y, Oldenhove G. Tuning microenvironments: induction of regulatory T cells by dendritic cells. Immunity. 2008;29(3):362-371.
    • (2008) Immunity , vol.29 , Issue.3 , pp. 362-371
    • Belkaid, Y.1    Oldenhove, G.2
  • 8
    • 65549123867 scopus 로고    scopus 로고
    • Natural and adaptive foxp3+ regulatory T cells: More of the same or a division of labor?
    • Curotto de Lafaille MA, Lafaille JJ. Natural and adaptive foxp3+ regulatory T cells: more of the same or a division of labor? Immunity. 2009;30(5):626-635.
    • (2009) Immunity , vol.30 , Issue.5 , pp. 626-635
    • Curotto De Lafaille, M.A.1    Lafaille, J.J.2
  • 9
    • 63149172076 scopus 로고    scopus 로고
    • Dendritic cells as controllers of antigen-specific Foxp3+ regulatory T cells
    • Yamazaki S, Steinman RM. Dendritic cells as controllers of antigen-specific Foxp3+ regulatory T cells. J Dermatol Sci. 2009;54(2):69-75.
    • (2009) J Dermatol Sci , vol.54 , Issue.2 , pp. 69-75
    • Yamazaki, S.1    Steinman, R.M.2
  • 11
  • 13
    • 77950408684 scopus 로고    scopus 로고
    • Skin-draining lymph nodes contain dermis-derived CD103(-) dendritic cells that constitutively produce retinoic acid and induce Foxp3(+) regulatory T cells
    • Guilliams M, Crozat K, Henri S, et al. Skin-draining lymph nodes contain dermis-derived CD103(-) dendritic cells that constitutively produce retinoic acid and induce Foxp3(+) regulatory T cells. Blood. 2010;115(10):1958-1968.
    • (2010) Blood , vol.115 , Issue.10 , pp. 1958-1968
    • Guilliams, M.1    Crozat, K.2    Henri, S.3
  • 15
    • 0030045373 scopus 로고    scopus 로고
    • Ig-specific T cell receptor-transgenic T cells are not deleted in the thymus and are functional in vivo
    • DOI 10.1084/jem.183.1.203
    • Granucci F, Rescigno M, Marconi G, Foti M, Ricciardi-Castagnoli P. Ig-specific T cell receptor-transgenic T cells are not deleted in the thymus and are functional in vivo. J Exp Med. 1996; 183(1):203-213. (Pubitemid 26028760)
    • (1996) Journal of Experimental Medicine , vol.183 , Issue.1 , pp. 203-213
    • Granucci, F.1    Rescigno, M.2    Marconi, G.3    Foti, M.4    Ricciardi-Castagnoli, P.5
  • 16
    • 0028233838 scopus 로고
    • Production of soluble MHC class II proteins with covalently bound single peptides
    • DOI 10.1038/369151a0
    • Kozono H, White J, Clements J, Marrack P, Kappler J. Production of soluble MHC class II proteins with covalently bound single peptides. Nature. 1994;369(6476):151-154. (Pubitemid 24153438)
    • (1994) Nature , vol.369 , Issue.6476 , pp. 151-154
    • Kozono, H.1    White, J.2    Clements, J.3    Marrack, P.4    Kappler, J.5
  • 17
    • 0022549802 scopus 로고
    • Regulated expression of human (A)γ-, β-, and hybrid βγ-globin genes in transgenic mice: Manipulation of the developmental expression patterns
    • Kollias G, Wrighton N, Hurst J, Grosveld F. Regulated expression of human A gamma-, beta-, and hybrid gamma beta-globin genes in transgenic mice: manipulation of the developmental expression patterns. Cell. 1986;46(1):89-94. (Pubitemid 16027828)
    • (1986) Cell , vol.46 , Issue.1 , pp. 89-94
    • Kollias, G.1    Wrighton, N.2    Hurst, J.3    Grosveld, F.4
  • 18
    • 33646048351 scopus 로고    scopus 로고
    • Induction of peripheral T cell tolerance by antigen-presenting B cells. I. Relevance of antigen presentation persistence
    • Raimondi G, Zanoni I, Citterio S, Ricciardi-Castagnoli P, Granucci F. Induction of peripheral T-cell tolerance by antigen-presenting B cells: I. Relevance of antigen presentation persistence. J Immunol. 2006;176(7):4012-4020. (Pubitemid 44264379)
    • (2006) Journal of Immunology , vol.176 , Issue.7 , pp. 4012-4020
    • Raimondi, G.1    Zanoni, I.2    Citterio, S.3    Ricciardi-Castagnoli, P.4    Granucci, F.5
  • 21
    • 28744458859 scopus 로고    scopus 로고
    • Bioconductor: Open software development for computational biology and bioinformatics
    • Gentleman RC, Carey VJ, Bates DM, et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol. 2004;5(10):R80.
    • (2004) Genome Biol , vol.5 , Issue.10
    • Gentleman, R.C.1    Carey, V.J.2    Bates, D.M.3
  • 23
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical bayes methods for assessing differential expression in microarray experiments
    • Article3
    • Smyth GK. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol. 2004;3:Article3.
    • (2004) Stat Appl Genet Mol Biol , vol.3
    • Smyth, G.K.1
  • 25
    • 0031058466 scopus 로고    scopus 로고
    • Targeted expression of major histocompatibility complex (MHC) class II molecules demonstrates that dendritic cells can induce negative but not positive selection of thymocytes in vivo
    • DOI 10.1084/jem.185.3.541
    • Brocker T, Riedinger M, Karjalainen K. Targeted expression of major histocompatibility complex (MHC) class II molecules demonstrates that dendritic cells can induce negative but not positive selection of thymocytes in vivo. J Exp Med. 1997;185(3):541-550. (Pubitemid 27078372)
    • (1997) Journal of Experimental Medicine , vol.185 , Issue.3 , pp. 541-550
    • Brocker, T.1    Riedinger, M.2    Karjalainen, K.3
  • 26
    • 0030727150 scopus 로고    scopus 로고
    • Survival of mature CD4 T lymphocytes is dependent on major histocompatibility complex class II-expressing dendritic cells
    • DOI 10.1084/jem.186.8.1223
    • Brocker T. Survival of mature CD4 T lymphocytes is dependent on major histocompatibility complex class II-expressing dendritic cells. J Exp Med. 1997;186(8):1223-1232. (Pubitemid 27469017)
    • (1997) Journal of Experimental Medicine , vol.186 , Issue.8 , pp. 1223-1232
    • Brocker, T.1
  • 27
    • 58149280443 scopus 로고    scopus 로고
    • Lymph-migrating, tissue-derived dendritic cells are minor constituents within steady-state lymph nodes
    • Jakubzick C, Bogunovic M, Bonito AJ, Kuan EL, Merad M, Randolph GJ. Lymph-migrating, tissue-derived dendritic cells are minor constituents within steady-state lymph nodes. J Exp Med. 2008;205(12):2839-2850.
    • (2008) J Exp Med , vol.205 , Issue.12 , pp. 2839-2850
    • Jakubzick, C.1    Bogunovic, M.2    Bonito, A.J.3    Kuan, E.L.4    Merad, M.5    Randolph, G.J.6
  • 28
    • 76249088374 scopus 로고    scopus 로고
    • Thymus-blood protein interactions are highly effective in negative selection and regulatory T cell induction
    • Atibalentja DF, Byersdorfer CA, Unanue ER. Thymus-blood protein interactions are highly effective in negative selection and regulatory T cell induction. J Immunol. 2009;183(12):7909-7918.
    • (2009) J Immunol , vol.183 , Issue.12 , pp. 7909-7918
    • Atibalentja, D.F.1    Byersdorfer, C.A.2    Unanue, E.R.3
  • 31
    • 70350478405 scopus 로고    scopus 로고
    • Retinoic acid can enhance conversion of naive into regulatory T cells independently of secreted cytokines
    • Nolting J, Daniel C, Reuter S, et al. Retinoic acid can enhance conversion of naive into regulatory T cells independently of secreted cytokines. J Exp Med. 2009;206(10):2131-2139.
    • (2009) J Exp Med , vol.206 , Issue.10 , pp. 2131-2139
    • Nolting, J.1    Daniel, C.2    Reuter, S.3
  • 32
    • 55549084247 scopus 로고    scopus 로고
    • Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells
    • Hill JA, Hall JA, Sun CM, et al. Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells. Immunity. 2008;29(5):758-770.
    • (2008) Immunity , vol.29 , Issue.5 , pp. 758-770
    • Hill, J.A.1    Hall, J.A.2    Sun, C.M.3
  • 33
    • 5644300399 scopus 로고    scopus 로고
    • Retinoic acid imprints gut-homing specificity on T cells
    • DOI 10.1016/j.immuni.2004.08.011, PII S107476130400247X
    • Iwata M, Hirakiyama A, Eshima Y, Kagechika H, Kato C, Song SY. Retinoic acid imprints gut-homing specificity on T cells. Immunity. 2004;21(4):527-538. (Pubitemid 39370508)
    • (2004) Immunity , vol.21 , Issue.4 , pp. 527-538
    • Iwata, M.1    Hirakiyama, A.2    Eshima, Y.3    Kagechika, H.4    Kato, C.5    Song, S.-Y.6
  • 34
    • 0032983330 scopus 로고    scopus 로고
    • Identification of a novel class of retinoic acid receptor beta-selective retinoid antagonists and their inhibitory effects on AP-1 activity and retinoic acid-induced apoptosis in human breast cancer cells
    • Li Y, Hashimoto Y, Agadir A, Kagechika H, Zhang X. Identification of a novel class of retinoic acid receptor beta-selective retinoid antagonists and their inhibitory effects on AP-1 activity and retinoic acid-induced apoptosis in human breast cancer cells. J Biol Chem. 1999;274(22):15360-15366.
    • (1999) J Biol Chem , vol.274 , Issue.22 , pp. 15360-15366
    • Li, Y.1    Hashimoto, Y.2    Agadir, A.3    Kagechika, H.4    Zhang, X.5
  • 37
    • 48249150707 scopus 로고    scopus 로고
    • In silico identified CCR4 antagonists target regulatory T cells and exert adjuvant activity in vaccination
    • Bayry J, Tchilian EZ, Davies MN, et al. In silico identified CCR4 antagonists target regulatory T cells and exert adjuvant activity in vaccination. Proc Natl Acad Sci U S A. 2008;105(29):10221-10226.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.29 , pp. 10221-10226
    • Bayry, J.1    Tchilian, E.Z.2    Davies, M.N.3
  • 38
    • 0030770508 scopus 로고    scopus 로고
    • Immunity causing blindness: Five different paths to herpes stromal keratitis
    • DOI 10.1016/S0167-5699(97)01114-6, PII S0167569997011146
    • Streilein JW, Dana MR, Ksander BR. Immunity causing blindness: five different paths to herpes stromal keratitis. Immunol Today. 1997;18(9):443-449. (Pubitemid 27381987)
    • (1997) Immunology Today , vol.18 , Issue.9 , pp. 443-449
    • Streilein, J.W.1    Dana, M.R.2    Ksander, B.R.3
  • 39
    • 0032570826 scopus 로고    scopus 로고
    • Molecular mimicry by herpes simplex virus-type 1: Autoimmune disease after viral infection
    • DOI 10.1126/science.279.5355.1344
    • Zhao ZS, Granucci F, Yeh L, Schaffer PA, Cantor H. Molecular mimicry by herpes simplex virus-type 1: autoimmune disease after viral infection. Science. 1998;279(5355):1344-1347. (Pubitemid 28119574)
    • (1998) Science , vol.279 , Issue.5355 , pp. 1344-1347
    • Zhao, Z.-S.1    Granucci, F.2    Yeh, L.3    Schaffer, P.A.4    Cantor, H.5
  • 40
    • 79955700323 scopus 로고    scopus 로고
    • In vivo depletion of FoxP3+ Tregs using the DEREG mouse model
    • Lahl K, Sparwasser T. In vivo depletion of FoxP3+ Tregs using the DEREG mouse model. Methods Mol Biol. 2011;707:157-172.
    • (2011) Methods Mol Biol , vol.707 , pp. 157-172
    • Lahl, K.1    Sparwasser, T.2
  • 41
    • 77954932467 scopus 로고    scopus 로고
    • Programming dendritic cells to induce T(H)2 and tolerogenic responses
    • Pulendran B, Tang H, Manicassamy S. Programming dendritic cells to induce T(H)2 and tolerogenic responses. Nat Iimmunol. 2010;11(8):647-655.
    • (2010) Nat Iimmunol , vol.11 , Issue.8 , pp. 647-655
    • Pulendran, B.1    Tang, H.2    Manicassamy, S.3
  • 42
    • 63649135273 scopus 로고    scopus 로고
    • GM-CSF and IL-4 synergistically trigger dendritic cells to acquire retinoic acid-producing capacity
    • Yokota A, Takeuchi H, Maeda N, et al. GM-CSF and IL-4 synergistically trigger dendritic cells to acquire retinoic acid-producing capacity. Int Immunol. 2009;21(4):361-377.
    • (2009) Int Immunol , vol.21 , Issue.4 , pp. 361-377
    • Yokota, A.1    Takeuchi, H.2    Maeda, N.3
  • 45
    • 58149177778 scopus 로고    scopus 로고
    • CD8+ CD205+ splenic dendritic cells are specialized to induce Foxp3+ regulatory T cells
    • Yamazaki S, Dudziak D, Heidkamp GF, et al. CD8+ CD205+ splenic dendritic cells are specialized to induce Foxp3+ regulatory T cells. J Immunol. 2008;181(10):6923-6933.
    • (2008) J Immunol , vol.181 , Issue.10 , pp. 6923-6933
    • Yamazaki, S.1    Dudziak, D.2    Heidkamp, G.F.3
  • 46
    • 79960369940 scopus 로고    scopus 로고
    • Prevention of type 1 diabetes in mice by tolerogenic vaccination with a strong agonist insulin mimetope
    • Daniel C, Weigmann B, Bronson R, von Boehmer H. Prevention of type 1 diabetes in mice by tolerogenic vaccination with a strong agonist insulin mimetope. J Exp Med. 2011;208(7):1501-1510.
    • (2011) J Exp Med , vol.208 , Issue.7 , pp. 1501-1510
    • Daniel, C.1    Weigmann, B.2    Bronson, R.3    Von Boehmer, H.4
  • 47
    • 64149088746 scopus 로고    scopus 로고
    • Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity
    • Manicassamy S, Ravindran R, Deng J, et al. Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity. Nat Med. 2009;15(4):401-409.
    • (2009) Nat Med , vol.15 , Issue.4 , pp. 401-409
    • Manicassamy, S.1    Ravindran, R.2    Deng, J.3
  • 48
    • 79960453738 scopus 로고    scopus 로고
    • A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity
    • Haribhai D, Williams JB, Jia S, et al. A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity. Immunity. 2011;35(1):109-122.
    • (2011) Immunity , vol.35 , Issue.1 , pp. 109-122
    • Haribhai, D.1    Williams, J.B.2    Jia, S.3
  • 51
    • 77955391804 scopus 로고    scopus 로고
    • TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo
    • Gottschalk RA, Corse E, Allison JP. TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo. J Exp Med. 2010;207(8):1701- 1711.
    • (2010) J Exp Med , vol.207 , Issue.8 , pp. 1701-1711
    • Gottschalk, R.A.1    Corse, E.2    Allison, J.P.3
  • 52
    • 44949265934 scopus 로고
    • Multiple levels of peripheral tolerance
    • Arnold B, Schonrich G, Hammerling GJ. Multiple levels of peripheral tolerance. Immunol Today. 1993;14(1):12-14. (Pubitemid 23028244)
    • (1993) Immunology Today , vol.14 , Issue.1 , pp. 12-14
    • Arnold, B.1    Schonrich, G.2    Hammerling, G.J.3
  • 53
    • 0028957496 scopus 로고
    • Anergy and exhaustion are independent mechanisms of peripheral T-cell tolerance
    • Rocha B, Grandien A, Freitas AA. Anergy and exhaustion are independent mechanisms of peripheral T-cell tolerance. J Exp Med. 1995;181(3):993-1003.
    • (1995) J Exp Med , vol.181 , Issue.3 , pp. 993-1003
    • Rocha, B.1    Grandien, A.2    Freitas, A.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.