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Volumn 183, Issue 1, 1996, Pages 203-213

Ig-specific T cell receptor-transgenic T cells are not deleted in the thymus and are functional in vivo

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN; T LYMPHOCYTE RECEPTOR;

EID: 0030045373     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.183.1.203     Document Type: Article
Times cited : (23)

References (43)
  • 1
    • 0020977755 scopus 로고
    • Cellular mechanisms of immunological tolerance
    • Nossal, G.J.V. 1983. Cellular mechanisms of immunological tolerance. Annu. Rev. Immunol. 1:33-62.
    • (1983) Annu. Rev. Immunol. , vol.1 , pp. 33-62
    • Nossal, G.J.V.1
  • 2
    • 0028151819 scopus 로고
    • Negative selection of lymphocytes
    • Nossal, G.J.V. 1994. Negative selection of lymphocytes. Cell. 76:229-239.
    • (1994) Cell , vol.76 , pp. 229-239
    • Nossal, G.J.V.1
  • 4
    • 0024307348 scopus 로고
    • Tolerance induction in double specific T cell receptor transgenic mice vanes with antigen
    • Pircher, H., K. Bürki, R. Lang, H. Hengartner, and R.M. Zinkernagel. 1989. Tolerance induction in double specific T cell receptor transgenic mice vanes with antigen. Nature (Lond.). 342:559-561.
    • (1989) Nature (Lond.) , vol.342 , pp. 559-561
    • Pircher, H.1    Bürki, K.2    Lang, R.3    Hengartner, H.4    Zinkernagel, R.M.5
  • 5
    • 0028032155 scopus 로고
    • Positive selection of lymphocytes
    • von Boehmer, H. 1994. Positive selection of lymphocytes. Cell 76:219-228.
    • (1994) Cell , vol.76 , pp. 219-228
    • Von Boehmer, H.1
  • 7
    • 0027468174 scopus 로고
    • Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity
    • Goverman, J., A. Woods, L. Larson, L.P. Weiner, L. Hood, and D.M. Zaller. 1993. Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity. Cell. 72:551-560.
    • (1993) Cell , vol.72 , pp. 551-560
    • Goverman, J.1    Woods, A.2    Larson, L.3    Weiner, L.P.4    Hood, L.5    Zaller, D.M.6
  • 8
    • 0027378612 scopus 로고
    • Following a diabetogenic T cell from genesis through pathogenesis
    • Katz, J.D., B. Wang, K. Haskins, C. Benoist, and D. Mathis. 1993. Following a diabetogenic T cell from genesis through pathogenesis. Cell. 74:1089-1100.
    • (1993) Cell , vol.74 , pp. 1089-1100
    • Katz, J.D.1    Wang, B.2    Haskins, K.3    Benoist, C.4    Mathis, D.5
  • 9
    • 0028102655 scopus 로고
    • High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice
    • Lafaille, J.J., K. Nagashima, M. Katsuki, and S. Tonegawa, 1994. High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice. Cell. 78:399-408.
    • (1994) Cell , vol.78 , pp. 399-408
    • Lafaille, J.J.1    Nagashima, K.2    Katsuki, M.3    Tonegawa, S.4
  • 11
    • 0025161357 scopus 로고
    • A peripheral mechanism preserves self-tolerance to a secreted protein in transgenic mice
    • Whiteley, P.J., N.J. Poindexter, C. Landon, and J.A. Kapp. 1990. A peripheral mechanism preserves self-tolerance to a secreted protein in transgenic mice. J. Immunol. 145:1376-1381.
    • (1990) J. Immunol. , vol.145 , pp. 1376-1381
    • Whiteley, P.J.1    Poindexter, N.J.2    Landon, C.3    Kapp, J.A.4
  • 12
    • 0024121508 scopus 로고
    • Alloreactive immune responses of transgenic mice expressing a foreign transplantation antigen in a soluble form
    • Arnold, B., O. Dill, G. Küblbeck, L. Jatsch, M.M. Simon, J. Tucker, and G. Hammerling. 1988. Alloreactive immune responses of transgenic mice expressing a foreign transplantation antigen in a soluble form. Proc. Natl. Acad. Sci. USA. 85: 2269-2273.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 2269-2273
    • Arnold, B.1    Dill, O.2    Küblbeck, G.3    Jatsch, L.4    Simon, M.M.5    Tucker, J.6    Hammerling, G.7
  • 13
    • 0027940262 scopus 로고
    • The mechanism of tolerance induction in MHC class II restricted T cells specific for a blood borne self antigen
    • Zal, T , A. Volkmann, and B. Stockinger. 1994. The mechanism of tolerance induction in MHC class II restricted T cells specific for a blood borne self antigen. J. Exp. Med. 180: 2089-2099.
    • (1994) J. Exp. Med. , vol.180 , pp. 2089-2099
    • Zal, T.1    Volkmann, A.2    Stockinger, B.3
  • 14
    • 0027458694 scopus 로고
    • Clonal deletion of specific thymocytes by an immunoglobulin idiotype
    • Bogen, B., Z. Dembic, and S. Weiss. 1993. Clonal deletion of specific thymocytes by an immunoglobulin idiotype. EMBO (Eur. Mol. Biol. Organ.) J. 12:357-363.
    • (1993) EMBO (Eur. Mol. Biol. Organ.) J. , vol.12 , pp. 357-363
    • Bogen, B.1    Dembic, Z.2    Weiss, S.3
  • 15
    • 0026586688 scopus 로고
    • Weak positive selection of transgenic T cell receptor-bearing thymocytes: Importance of major histocompatibihty complex class II, T cell receptor and CD4 surface molecule densities
    • Bogen, B., L. Gleditsch, S. Weiss, and Z. Dembic. 1992. Weak positive selection of transgenic T cell receptor-bearing thymocytes: importance of major histocompatibihty complex class II, T cell receptor and CD4 surface molecule densities. Eur. J. Immunol. 22:703-709.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 703-709
    • Bogen, B.1    Gleditsch, L.2    Weiss, S.3    Dembic, Z.4
  • 16
    • 0026451165 scopus 로고
    • B cells turn off virgin but not memory T cells
    • Fuchs, E.J., and P. Matzinger. 1992. B cells turn off virgin but not memory T cells. Science (Wash. DC). 258:1156-1159.
    • (1992) Science (Wash. DC) , vol.258 , pp. 1156-1159
    • Fuchs, E.J.1    Matzinger, P.2
  • 17
    • 0026031205 scopus 로고
    • MHC class II-restricted presentation of intracellular antigen
    • Weiss, S., and B. Bogen. 1991. MHC class II-restricted presentation of intracellular antigen. Cell. 64:767-776.
    • (1991) Cell , vol.64 , pp. 767-776
    • Weiss, S.1    Bogen, B.2
  • 18
    • 43949169661 scopus 로고
    • Do B cells drive the diversification of immune responses?
    • Mamula, M.J., and C.A. Janeway. 1993. Do B cells drive the diversification of immune responses? Immunol. Today. 14: 151-152.
    • (1993) Immunol. Today , vol.14 , pp. 151-152
    • Mamula, M.J.1    Janeway, C.A.2
  • 20
    • 0024212067 scopus 로고
    • Rapid production of full-length cDNAs from rare transcripts: Amplification using a single gene-specific oligonucleotide primer
    • Frohman, M.A., M.K. Dush, and G.R. Martin. 1988. Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer. Proc. Natl. Acad. Sci. USA. 85:8998-9002.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 8998-9002
    • Frohman, M.A.1    Dush, M.K.2    Martin, G.R.3
  • 23
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti, I., G. Migliorati, M.C. Pagliacci, F. Grignani, and C. Riccardi. 1991. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods. 139:271-279.
    • (1991) J. Immunol. Methods , vol.139 , pp. 271-279
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.5
  • 24
    • 0015198118 scopus 로고
    • Immunity in experimental salmonellosis. II. Basis for the avirulence and protective capacity of galE mutants of Salmonella typhimurium
    • Germanier, R., and E. Furer. 1971. Immunity in experimental salmonellosis. II. Basis for the avirulence and protective capacity of galE mutants of Salmonella typhimurium. Infect. Immun. 4:663-668.
    • (1971) Infect. Immun. , vol.4 , pp. 663-668
    • Germanier, R.1    Furer, E.2
  • 25
    • 0020333042 scopus 로고
    • Cloned T lymphocytes and monoclonal antibodies as probes for cell surface molecules active in T cell-mediated cytolysis
    • Sarmiento, M., D.P. Dialynas, D.W. Lancki, K.A. Wall, M.I. Lorber, M.R. Loken, and F.W. Fitch. 1982. Cloned T lymphocytes and monoclonal antibodies as probes for cell surface molecules active in T cell-mediated cytolysis. Immunol. Rev. 68:135-169.
    • (1982) Immunol. Rev. , vol.68 , pp. 135-169
    • Sarmiento, M.1    Dialynas, D.P.2    Lancki, D.W.3    Wall, K.A.4    Lorber, M.I.5    Loken, M.R.6    Fitch, F.W.7
  • 26
    • 0021052516 scopus 로고
    • Characterization of the murine T cell surface molecule designated L3T4, identified by the monoclonal antibody GK1.5: Similarities to the human Leu3/T4 molecule
    • Dialynas, D.P, Z.S. Quan, K.A. Wall, A. Pierres, J. Quintans, M.R. Loken, M. Pierres, and F.W. Fitck. 1983. Characterization of the murine T cell surface molecule designated L3T4, identified by the monoclonal antibody GK1.5: similarities to the human Leu3/T4 molecule. J. Immunol. 131:2445-2451.
    • (1983) J. Immunol. , vol.131 , pp. 2445-2451
    • Dialynas, D.P.1    Quan, Z.S.2    Wall, K.A.3    Pierres, A.4    Quintans, J.5    Loken, M.R.6    Pierres, M.7    Fitck, F.W.8
  • 28
    • 0004850959 scopus 로고
    • The enzyme-linked immunospot assay for detection of specific antibody-secreting cells: Methodology and applicability
    • D.M. Kemey and S.J. Challacombe, editors. John Wiley & Sons, Chichester and New York
    • Czerkinsky, C., L.A. Nilsson, A. Tarkowski, W.J. Koopman, J. Mestecky, and Ö. Ouchterlony. 1988. The enzyme-linked immunospot assay for detection of specific antibody-secreting cells: methodology and applicability. In Theoretical and Technical Aspects of ELISA and Other Solid Phase Immunoassay. D.M. Kemey and S.J. Challacombe, editors. John Wiley & Sons, Chichester and New York. 217-239.
    • (1988) Theoretical and Technical Aspects of ELISA and Other Solid Phase Immunoassay , pp. 217-239
    • Czerkinsky, C.1    Nilsson, L.A.2    Tarkowski, A.3    Koopman, W.J.4    Mestecky, J.5    Ouchterlony, Ö.6
  • 29
    • 0026048324 scopus 로고
    • + T cell clones of the Th1 subset selectively suppress the Igh-1b allotype in vivo
    • + T cell clones of the Th1 subset selectively suppress the Igh-1b allotype in vivo. Eur. J. Immunol. 21:2365-2371.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 2365-2371
    • Bartnes, K.1    Hannestad, K.2
  • 34
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavneli, Y., Y. Sherman, and S.A. Ben-Sasson. 1992. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119:493-501.
    • (1992) J. Cell Biol. , vol.119 , pp. 493-501
    • Gavneli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 35
    • 0024428184 scopus 로고
    • Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand
    • Berg, L.J., A.M. Pullen, B. Fazekas de St. Groth, D. Mathis, C. Benoist, and M.M. Davis. 1989. Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand. Cell. 58:1035-1046.
    • (1989) Cell , vol.58 , pp. 1035-1046
    • Berg, L.J.1    Pullen, A.M.2    Fazekas De St. Groth, B.3    Mathis, D.4    Benoist, C.5    Davis, M.M.6
  • 37
    • 0024454771 scopus 로고
    • Immunoglobulin-specific T-B cell interaction. I. Presentation of self immunoglobulin determinants by B lymphocytes
    • Rudensky, A.Y., and V.L. Yurin. 1989. Immunoglobulin-specific T-B cell interaction. I. Presentation of self immunoglobulin determinants by B lymphocytes. Eur. J. Immunol. 19: 1677-1683.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 1677-1683
    • Rudensky, A.Y.1    Yurin, V.L.2
  • 38
    • 0027451442 scopus 로고
    • Expression of two α chains on the surface of T cells in T cell receptor transgenic mice
    • Heath, W.R., and J.F A.P. Miller. 1993. Expression of two α chains on the surface of T cells in T cell receptor transgenic mice. J. Exp. Med. 178:1807-1811.
    • (1993) J. Exp. Med. , vol.178 , pp. 1807-1811
    • Heath, W.R.1    Miller, J.F.A.P.2
  • 39
    • 0025013368 scopus 로고
    • Presentation of endogenous immunoglobulin-recognizing T cell clones by thymic cells
    • Rudensky, A.Y., S.M. Mazel, and V.L. Yurin. 1990. Presentation of endogenous immunoglobulin-recognizing T cell clones by thymic cells. Eur. J. Immunol. 20:2235-2239.
    • (1990) Eur. J. Immunol. , vol.20 , pp. 2235-2239
    • Rudensky, A.Y.1    Mazel, S.M.2    Yurin, V.L.3
  • 40
    • 0018758477 scopus 로고
    • B-cell influences on the induction of allotype suppressor T cells
    • Black, S.J., and L.A. Herzenberg. 1979. B-cell influences on the induction of allotype suppressor T cells. J. Exp. Med. 150: 174-183.
    • (1979) J. Exp. Med. , vol.150 , pp. 174-183
    • Black, S.J.1    Herzenberg, L.A.2
  • 43
    • 0024434885 scopus 로고
    • Presentation of IgG2a antigens to class II-restricted T cells by stably transfected B lymphoma cells
    • Bikoff, E.K., and L.A. Eckhardt. 1989. Presentation of IgG2a antigens to class II-restricted T cells by stably transfected B lymphoma cells. Eur. J. Immunol. 19:1903-1909.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 1903-1909
    • Bikoff, E.K.1    Eckhardt, L.A.2


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