Structure of the Alk1 extracellular domain and characterization of its bone morphogenetic protein (BMP) binding properties

Biochemistry

Volumn 51, Issue 32, 2012, Pages 6328-6341

  Mahlawat, Pardeep ^a   Ilangovan, Udayar ^a   Biswas, Tanuka ^a   Sun, Lu Zhe ^a   Hinck, Andrew P ^a  

^a Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROPERTIES; BONE MORPHOGENETIC PROTEINS; EXTRACELLULAR DOMAINS; HYDROPHOBIC INTERFACE; MUTATIONAL ANALYSIS; N-TERMINALS; SIGNALING PROTEINS; TYPE II;

BINDING ENERGY;

PROTEINS;

ACTIVIN RECEPTOR LIKE KINASE 1; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 9; BONE MORPHOGENETIC PROTEIN RECEPTOR 1A; BONE MORPHOGENETIC PROTEIN RECEPTOR 1B; OSTEOGENIC PROTEIN 1;

AMINO TERMINAL SEQUENCE; ARTICLE; BETA SHEET; CARBON NUCLEAR MAGNETIC RESONANCE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; ENZYME STRUCTURE; HYDROPHOBICITY; MOLECULAR DYNAMICS; MOLECULAR MODEL; MUTATION; NITROGEN NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ACTIVIN RECEPTORS, TYPE II; AMINO ACID SEQUENCE; ANIMALS; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE I; BONE MORPHOGENETIC PROTEINS; GROWTH DIFFERENTIATION FACTORS; HUMANS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NIH 3T3 CELLS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; TRANSFECTION;

EID: 84865124878     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi300942x     Document Type: Article

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