Rapid structural fluctuations of the free HIV protease flaps in solution: Relationship to crystal structures and comparison with predictions of dynamics calculations

Protein Science

Volumn 11, Issue 2, 2002, Pages 221-232

  Freedberg, Darón I ^a   Ishima, Rieko ^a   Jacob, Jaison ^a   Wang, Yun Xing ^a   Kustanovich, Irina ^b   Louis, John M ^c   Torchia, Dennis A ^a,d  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^d NONE   (United States)

Author keywords

AIDS; Hydrogen bonds; NMR; Relaxation; Secondary structure

Indexed keywords

HYDROGEN; LIGAND; NITROGEN 15; PROTEINASE; VIRUS ENZYME;

ARTICLE; CALCULATION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME STRUCTURE; HUMAN IMMUNODEFICIENCY VIRUS; HYDROGEN BOND; MEASUREMENT; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; POINT MUTATION; PREDICTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SECONDARY STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY;

AMINO ACID SEQUENCE; BINDING SITES; HIV PROTEASE; HUMANS; HYDROGEN BONDING; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MATHEMATICAL COMPUTING; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN CONFORMATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 0036147844     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.33202     Document Type: Article

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