The Human Kinetochore Ska1 Complex Facilitates Microtubule Depolymerization-Coupled Motility

Developmental Cell

Volumn 16, Issue 3, 2009, Pages 374-385

  Welburn, Julie P I ^a   Grishchuk, Ekaterina L ^b   Backer, Chelsea B ^a   Wilson Kubalek, Elizabeth M ^c   Yates III, John R ^c   Cheeseman, Iain M ^a  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

CELLBIO

Indexed keywords

BINDING PROTEIN; SPINDLE AND KINETOCHORE ASSOCIATED PROTEIN 1; UNCLASSIFIED DRUG;

ARTICLE; CENTROMERE; CHROMOSOME SEGREGATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MICROTUBULE ASSEMBLY; MITOSIS SPINDLE; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN FUNCTION;

BASE SEQUENCE; CELL LINE; CHROMOSOMAL PROTEINS, NON-HISTONE; CHROMOSOME SEGREGATION; FUNGAL PROTEINS; HUMANS; KINETOCHORES; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSPHERES; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; MITOSIS; MODELS, BIOLOGICAL; MOVEMENT; MULTIPROTEIN COMPLEXES; PROTEIN BINDING; PROTEIN SUBUNITS; RNA, SMALL INTERFERING; SPECIES SPECIFICITY;

HARNESS; METAZOA; SACCHAROMYCETALES; VERTEBRATA;

EID: 61749084467     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devcel.2009.01.011     Document Type: Article

References (38)

1. Asbury C.L., Gestaut D.R., Powers A.F., Franck A.D., and Davis T.N. The Dam1 kinetochore complex harnesses microtubule dynamics to produce force and movement. Proc. Natl. Acad. Sci. USA 103 (2006) 9873-9878
2. Cantin G.T., Shock T.R., Park S.K., Madhani H.D., and Yates III J.R. Optimizing TiO2-based phosphopeptide enrichment for automated multidimensional liquid chromatography coupled to tandem mass spectrometry. Anal. Chem. 79 (2007) 4666-4673
3. Cheeseman I.M., and Desai A. A combined approach for the localization and tandem affinity purification of protein complexes from metazoans. Sci. STKE 2005 (2005) pl1
4. Cheeseman I.M., and Desai A. Molecular architecture of the kinetochore-microtubule interface. Nat. Rev. Mol. Cell Biol. 9 (2008) 33-46
5. Cheeseman I.M., Brew C., Wolyniak M., Desai A., Anderson S., Muster N., Yates J.R., Huffaker T.C., Drubin D.G., and Barnes G. Implication of a novel multiprotein Dam1p complex in outer kinetochore function. J. Cell Biol. 155 (2001) 1137-1146
6. Cheeseman I.M., Enquist-Newman M., Müller-Reichert T., Drubin D.G., and Barnes G. Mitotic spindle integrity and kinetochore function linked by the Duo1p/Dam1p complex. J. Cell Biol. 152 (2001) 197-212
7. Cheeseman I.M., Niessen S., Anderson S., Hyndman F., Yates III J.R., Oegema K., and Desai A. A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension. Genes Dev. 18 (2004) 2255-2268
8. Cheeseman I.M., Chappie J.S., Wilson-Kubalek E.M., and Desai A. The Conserved KMN network constitutes the core microtubule-binding site of the kinetochore. Cell 127 (2006) 983-997
9. Ciferri C., Pasqualato S., Screpanti E., Varetti G., Santaguida S., Dos Reis G., Maiolica A., Polka J., De Luca J.G., De Wulf P., et al. Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex. Cell 133 (2008) 427-439
10. DeLuca J.G., Moree B., Hickey J.M., Kilmartin J.V., and Salmon E.D. hNuf2 inhibition blocks stable kinetochore-microtubule attachment and induces mitotic cell death in HeLa cells. J. Cell Biol. 159 (2002) 549-555
11. DeLuca J.G., Gall W.E., Ciferri C., Cimini D., Musacchio A., and Salmon E.D. Kinetochore microtubule dynamics and attachment stability are regulated by Hec1. Cell 127 (2006) 969-982
12. Desai A., Rybina S., Muller-Reichert T., Shevchenko A., Shevchenko A., Hyman A., and Oegema K. KNL-1 directs assembly of the microtubule-binding interface of the kinetochore in C. elegans. Genes Dev. 17 (2003) 2421-2435
13. Emanuele M.J., and Stukenberg P.T. Xenopus Cep57 is a novel kinetochore component involved in microtubule attachment. Cell 130 (2007) 893-905
14. Grishchuk E.L., Molodtsov M.I., Ataullakhanov F.I., and McIntosh J.R. Force production by disassembling microtubules. Nature 438 (2005) 384-388
15. Grishchuk E.L., Efremov A.K., Volkov V.A., Spiridonov I.S., Gudimchuk N., Westermann S., Drubin D., Barnes G., McIntosh J.R., and Ataullakhanov F.I. The Dam1 ring binds microtubules strongly enough to be a processive as well as energy-efficient coupler for chromosome motion. Proc. Natl. Acad. Sci. USA 105 (2008) 15423-15428
16. Grishchuk E.L., Spiridonov I.S., Volkov V.A., Efremov A., Westermann S., Drubin D., Barnes G., Ataullakhanov F.I., and McIntosh J.R. Different assemblies of the DAM1 complex follow shortening microtubules by distinct mechanisms. Proc. Natl. Acad. Sci. USA 105 (2008) 6918-6923
17. Hanisch A., Sillje H.H., and Nigg E.A. Timely anaphase onset requires a novel spindle and kinetochore complex comprising Ska1 and Ska2. EMBO J. 25 (2006) 5504-5515
18. Hofmann C., Cheeseman I.M., Goode B.L., McDonald K.L., Barnes G., and Drubin D.G. Saccharomyces cerevisiae Duo1p and Dam1p, novel proteins involved in mitotic spindle function. J. Cell Biol. 143 (1998) 1029-1040
19. Janke C., Ortiz J., Tanaka T.U., Lechner J., and Schiebel E. Four new subunits of the Dam1-Duo1 complex reveal novel functions in sister kinetochore biorientation. EMBO J. 21 (2002) 181-193
20. Jones M.H., He X., Giddings T.H., and Winey M. Yeast Dam1p has a role at the kinetochore in assembly of the mitotic spindle. Proc. Natl. Acad. Sci. USA 98 (2001) 13675-13680
21. Kline S.L., Cheeseman I.M., Hori T., Fukagawa T., and Desai A. The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation. J. Cell Biol. 173 (2006) 9-17
22. Kops G.J., Kim Y., Weaver B.A., Mao Y., McLeod I., Yates III J.R., Tagaya M., and Cleveland D.W. ZW10 links mitotic checkpoint signaling to the structural kinetochore. J. Cell Biol. 169 (2005) 49-60
23. Li Y., Bachant J., Alcasabas A.A., Wang Y., Qin J., and Elledge S.J. The mitotic spindle is required for loading of the DASH complex onto the kinetochore. Genes Dev. 16 (2002) 183-197
24. Liu X., McLeod I., Anderson S., Yates III J.R., and He X. Molecular analysis of kinetochore architecture in fission yeast. EMBO J. 24 (2005) 2919-2930
25. McIntosh J.R., Grishchuk E.L., Morphew M.K., Efremov A.K., Zhudenkov K., Volkov V.A., Cheeseman I.M., Desai A., Mastronarde D.N., and Ataullakhanov F.I. Fibrils connect microtubule tips with kinetochores: a mechanism to couple tubulin dynamics to chromosome motion. Cell 135 (2008) 322-333
26. Miranda J.J., De Wulf P., Sorger P.K., and Harrison S.C. The yeast DASH complex forms closed rings on microtubules. Nat. Struct. Mol. Biol. 12 (2005) 138-143
27. Porter I.M., McClelland S.E., Khoudoli G.A., Hunter C.J., Andersen J.S., McAinsh A.D., Blow J.J., and Swedlow J.R. Bod1, a novel kinetochore protein required for chromosome biorientation. J. Cell Biol. 179 (2007) 187-197
28. Sanchez-Perez I., Renwick S.J., Crawley K., Karig I., Buck V., Meadows J.C., Franco-Sanchez A., Fleig U., Toda T., and Millar J.B. The DASH complex and Klp5/Klp6 kinesin coordinate bipolar chromosome attachment in fission yeast. EMBO J. 24 (2005) 2931-2943
29. Siegel L.M., and Monty K.J. Determination of molecular weights and frictional ratios of proteins in impure systems by use of gel filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases. Biochim. Biophys. Acta 112 (1966) 346-362
30. Steegmaier M., Yang B., Yoo J.S., Huang B., Shen M., Yu S., Luo Y., and Scheller R.H. Three novel proteins of the syntaxin/SNAP-25 family. J. Biol. Chem. 273 (1998) 34171-34179
31. Tan S. A modular polycistronic expression system for overexpressing protein complexes in Escherichia coli. Protein Expr. Purif. 21 (2001) 224-234
32. Tanaka T.U., and Desai A. Kinetochore-microtubule interactions: the means to the end. Curr. Opin. Cell Biol. 20 (2008) 53-63
33. Tanaka K., Kitamura E., Kitamura Y., and Tanaka T.U. Molecular mechanisms of microtubule-dependent kinetochore transport toward spindle poles. J. Cell Biol. 178 (2007) 269-281
34. Washburn M.P., Wolters D., and Yates III J.R. Large-scale analysis of the yeast proteome by multidimensional protein identification technology. Nat. Biotechnol. 19 (2001) 242-247
35. Wei R.R., Al-Bassam J., and Harrison S.C. The Ndc80/HEC1 complex is a contact point for kinetochore-microtubule attachment. Nat. Struct. Mol. Biol. 14 (2007) 54-59
36. Westermann S., Avila-Sakar A., Wang H.W., Niederstrasser H., Wong J., Drubin D.G., Nogales E., and Barnes G. Formation of a dynamic kinetochore- microtubule interface through assembly of the Dam1 ring complex. Mol. Cell 17 (2005) 277-290
37. Westermann S., Wang H.W., Avila-Sakar A., Drubin D.G., Nogales E., and Barnes G. The Dam1 kinetochore ring complex moves processively on depolymerizing microtubule ends. Nature 440 (2006) 565-569
38. Wilson-Kubalek E.M., Cheeseman I.M., Yoshioka C., Desai A., and Milligan R.A. Orientation and structure of the Ndc80 complex on the microtubule lattice. J. Cell Biol. 182 (2008) 1055-1061