Left-shifted Nav channels in injured bilayer: Primary targets for neuroprotective Nav antagonists?

Frontiers in Pharmacology

Volumn 3 FEB, Issue , 2012, Pages

  Morris, Catherine E ^a   Boucher, Pierre Alexandre ^b   Joós, Béla ^b  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b Université d Ottawa et Institut de Physique Ottawa Carleton   (Canada)

Author keywords

Modeling; Ranolazine; Riluzole; Simulation; Spinal; Traumatic brain injury

Indexed keywords

ARACHNID VENOM; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL DIHYDROPYRIDINE TYPE ANTAGONIST; CALPAIN; CINCHOCAINE; DIAZEPAM; DIHYDROPYRIDINE DERIVATIVE; F 15845; GUANINE NUCLEOTIDE BINDING PROTEIN; IBUPROFEN; INDACATEROL; MEXILETINE; MIDAZOLAM; PROPOFOL; RANOLAZINE; RILUZOLE; SALMETEROL; SODIUM CALCIUM EXCHANGE PROTEIN; SODIUM CHANNEL NAV1.2; SODIUM CHANNEL NAV1.5; SODIUM CHANNEL NAV1.6; TETRACAINE; TETRODOTOXIN; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL BLOCKING AGENT;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BINDING AFFINITY; BRAIN ISCHEMIA; CARPAL TUNNEL SYNDROME; CELL DAMAGE; CEREBROVASCULAR ACCIDENT; CHANNEL GATING; COLITIS; DIABETIC NEUROPATHY; DRUG ACTIVITY; DRUG BINDING; DRUG BIOAVAILABILITY; DRUG EFFICACY; DRUG POTENCY; DRUG POTENTIATION; ENCEPHALITIS; ENTROPY; EPILEPTIC STATE; EXCITOTOXICITY; HEART ARRHYTHMIA; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HUMAN; HYSTERESIS; LIPOPHILICITY; MEMBRANE BIOLOGY; MULTIPLE SCLEROSIS; MUSCULAR DYSTROPHY; MYELINATED NERVE; NAV CHANNEL LEAK; NERVE CELL; NERVE CELL EXCITABILITY; NERVE FIBER MEMBRANE; NEUROPATHIC PAIN; NEUROPROTECTION; NONHUMAN; POSITIVE FEEDBACK; PULPITIS; RANVIER NODE; REPERFUSION INJURY; SHIFT TO THE LEFT; SICK EXCITABLE CELL; SODIUM CURRENT; SPINAL CORD INJURY; TRAUMATIC BRAIN INJURY; UNSPECIFIED SIDE EFFECT;

EID: 84864842078     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2012.00019     Document Type: Article

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