Using ortholog sequence data to predict the functional relevance of mutations in G-protein-coupled receptors

FASEB Journal

Volumn 26, Issue 8, 2012, Pages 3273-3281

  Cöster, Maxi ^a   Wittkopf, Doreen ^a   Kreuchwig, Annika ^b   Kleinau, Gunnar ^c   Thor, Doreen ^a   Krause, Gerd ^b   Schöneberg, Torsten ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Evolution; Mutagenesis; Nucleotide receptor; Structure function relationship

Indexed keywords

G PROTEIN COUPLED RECEPTOR; PURINERGIC P2Y12 RECEPTOR;

AMINO ACID SUBSTITUTION; ARTICLE; GENE MUTATION; GENETIC VARIABILITY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; EVOLUTION, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; RECEPTORS, PURINERGIC P2Y12; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY, AMINO ACID;

VERTEBRATA;

EID: 84864780265     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.12-203737     Document Type: Article

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