Comparison of three GPCR structural templates for modeling of the P2Y 12 nucleotide receptor

Journal of Computer-Aided Molecular Design

Volumn 25, Issue 4, 2011, Pages 329-338

  Deflorian, Francesca ^a   Jacobson, Kenneth A ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Antithrombotic drugs; Docking; G protein coupled receptor; Homology modeling; Nucleotides; Purines

Indexed keywords

AROMATIC COMPOUNDS; CELL MEMBRANES; COVALENT BONDS; KETONES; LIGANDS; MUTAGENESIS; PROTEINS; SULFUR COMPOUNDS;

ANTITHROMBOTIC; ANTITHROMBOTIC DRUG; CHEMOKINE RECEPTORS; DIASTEREOISOMERS; DISULPHIDE BRIDGE; DOCKING; G PROTEIN COUPLED RECEPTORS; HOMOLOGY MODELING; PURINE; STRUCTURAL TEMPLATES;

NUCLEOTIDES;

ADENOSINE A2A RECEPTOR; ARGININE; CHEMOKINE RECEPTOR CXCR4; CLOPIDOGREL; G PROTEIN COUPLED RECEPTOR; LYSINE; PURINERGIC P2Y RECEPTOR AGONIST; PURINERGIC P2Y RECEPTOR ANTAGONIST; PURINERGIC P2Y12 RECEPTOR; RHODOPSIN; SULFONIC ACID DERIVATIVE;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING KINETICS; CELL SURFACE; CONTROLLED STUDY; COVALENT BOND; DIASTEREOISOMER; DISULFIDE BOND; DNA TEMPLATE; INTERMETHOD COMPARISON; ISOMER; MOLECULAR DOCKING; MOLECULAR MODEL; PREDICTION; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; STRUCTURAL HOMOLOGY; STRUCTURE ANALYSIS;

EID: 79956223090     PISSN: 0920654X     EISSN: 15734951     Source Type: Journal    
DOI: 10.1007/s10822-011-9423-3     Document Type: Article

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