Involvement of the V2 vasopressin receptor in adaptation to limited water supply

PLoS ONE

Volumn 4, Issue 5, 2009, Pages

  Böselt, Iris ^a   Römpler, Holger ^a,b   Hermsdorf, Thomas ^a   Thor, Doreen ^a   Busch, Wibke ^a,c   Schulz, Angela ^a   Schöneberg, Torsten ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b HARVARD UNIVERSITY   (United States)

^c HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH UFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

VASOPRESSIN V2 RECEPTOR; VASOPRESSIN RECEPTOR;

ARTICLE; GENE MUTATION; GENETIC CONSERVATION; HABITUAL ADAPTATION; HOMEOSTASIS; HUMAN; KIDNEY CONCENTRATING CAPACITY; KIDNEY FUNCTION; MARSUPIAL; NEUROHYPOPHYSIS; NONHUMAN; PROTEIN FUNCTION; URINE OSMOLALITY; WATER ABSORPTION; WATER DEPRIVATION; WATER SUPPLY; ADAPTATION; ANIMAL; BIOLOGICAL MODEL; CELL STRAIN COS1; CERCOPITHECUS; ELECTROLYTE BALANCE; ENZYME LINKED IMMUNOSORBENT ASSAY; EXON; GENETICS; INTRON; MOLECULAR EVOLUTION; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; SITE DIRECTED MUTAGENESIS;

MAMMALIA; METATHERIA;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; BASE SEQUENCE; CERCOPITHECUS AETHIOPS; COS CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EVOLUTION, MOLECULAR; EXONS; HUMANS; INTRONS; MODELS, BIOLOGICAL; MUTAGENESIS, SITE-DIRECTED; RECEPTORS, VASOPRESSIN; WATER DEPRIVATION; WATER-ELECTROLYTE BALANCE;

EID: 65949118472     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0005573     Document Type: Article

References (57)

1. Liu AG, Seiffert ER, Simons EL (2008) Stable isotope evidence for an amphibious phase in early proboscidean evolution. Proc Natl Acad Sci U S A 105: 5786-5791.
2. Gaeth AP, Short RV, Renfree MB (1999) The developing renal, reproductive, and respiratory systems of the African elephant suggest an aquatic ancestry. Proc Natl Acad Sci U S A 96: 5555-5558.
3. Mbassa GK (1988) Mammalian renal modifications in dry environments. Vet Res Commun 12: 1-18.
4. Beuchat CA (1996) Structure and concentrating ability of the mammalian kidney: correlations with habitat. Am J Physiol 271: R157-179.
5. McCormick SD, Bradshaw D (2006) Hormonal control of salt and water balance in vertebrates. Gen Comp Endocrinol 147: 3-8.
6. Bradshaw D (2007) Environmental endocrinology. Gen Comp Endocrinol 152: 125-141.
7. Acher R (1996) Molecular evolution of fish neurohypophysial hormones: neutral and selective evolutionary mechanisms. Gen Comp Endocrinol 102: 157-172.
8. Suzuki M, Kubokawa K, Nagasawa H, Urano A (1995) Sequence analysis of vasotocin cDNAs of the lamprey, Lampetra japonica, and the hagfish, Eptatretus burgeri: evolution of cyclostome vasotocin precursors. J Mol Endocrinol 14: 67-77.
9. Acher R, Chauvet J, Chauvet MT, Rouille Y (1999) Unique evolution of neurohypophysial hormones in cartilaginous fishes: possible implications for urea-based osmoregulation. J Exp Zool 284: 475-484.
10. Gwee PC, Amemiya CT, Brenner S, Venkatesh B (2008) Sequence and organization of coelacanth neurohypophysial hormone genes: evolutionary history of the vertebrate neurohypophysial hormone gene locus. BMC Evol Biol 8: 93.
11. Takei Y, Kawakoshi A, Tsukada T, Yuge S, Ogoshi M, et al. (2006) Contribution of comparative fish studies to general endocrinology: structure and function of some osmoregulatory hormones. J Exp Zoolog A Comp Exp Biol 305: 787-798.
12. Perrott MN, Sainsbury RJ, Balment RJ (1993) Peptide hormone-stimulated second messenger production in the teleostean nephron. Gen Comp Endocrinol 89: 387-395.
13. Fujiwara TM, Bichet DG (2005) Molecular biology of hereditary diabetes insipidus. J Am Soc Nephrol 16: 2836-2846.
14. Luzius H, Jans DA, Grunbaum EG, Moritz A, Rascher W, et al. (1992) A low affinity vasopressin V2-receptor in inherited nephrogenic diabetes insipidus. J Recept Res 12: 351-368.
15. Schott HC 2nd, Bayly WM, Reed SM, Brobst DF (1993) Nephrogenic diabetes insipidus in sibling colts. J Vet Intern Med 7: 68-72.
16. Yun J, Schoneberg T, Liu J, Schulz A, Ecelbarger CA, et al. (2000) Generation and phenotype of mice harboring a nonsense mutation in the V2 vasopressin receptor gene. J Clin Invest 106: 1361-1371.
17. Pasel K, Schulz A, Timmermann K, Linnemann K, Hoeltzenbein M, et al. (2000) Functional characterization of the molecular defects causing nephrogenic diabetes insipidus in eight families. J Clin Endocrinol Metab 85: 1703-1710.
18. Schulz A, Sangkuhl K, Lennert T, Wigger M, Price DA, et al. (2002) Aminoglycoside pretreatment partially restores the function of truncated V(2) vasopressin receptors found in patients with nephrogenic diabetes insipidus. J Clin Endocrinol Metab 87: 5247-5257.
19. Feldman BJ, Rosenthal SM, Vargas GA, Fenwick RG, Huang EA, et al. (2005) Nephrogenic syndrome of inappropriate antidiuresis. N Engl J Med 352: 1884-1890.
20. Lefkowitz RJ, Cotecchia S, Samama P, Costa T (1993) Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins. Trends Pharmacol Sci 14: 303-307.
21. Sangkuhl K, Schulz A, Rompler H, Yun J, Wess J, et al. (2004) Aminoglycoside-mediated rescue of a disease-causing nonsense mutation in the V2 vasopressin receptor gene in vitro and in vivo. Hum Mol Genet 13: 893-903.
22. Sarmiento JM, Anazco CC, Campos DM, Prado GN, Navarro J, et al. (2004) Novel down-regulatory mechanism of the surface expression of the vasopressin V2 receptor by an alternative splice receptor variant. J Biol Chem 279: 47017-47023.
23. Firsov D, Mandon B, Morel A, Merot J, Le Maout S, et al. (1994) Molecular analysis of vasopressin receptors in the rat nephron. Evidence for alternative splicing of the V2 receptor. Pflugers Arch 429: 79-89.
24. Kamperis K, Siggaard C, Herlin T, Nathan E, Hertz JM, et al. (2000) A novel splicing mutation in the V2 vasopressin receptor. Pediatr Nephrol 15: 43-49.
25. Wildin RS, Cogdell DE, Valadez V (1998) AVPR2 variants and V2 vasopressin receptor function in nephrogenic diabetes insipidus. Kidney Int 54: 1909-1922.
26. Wildin RS, Antush MJ, Bennett RL, Schoof JM, Scott CR (1994) Heterogeneous AVPR2 gene mutations in congenital nephrogenic diabetes insipidus. Am J Hum Genet 55: 266-277.
27. Arthus MF, Lonergan M, Crumley MJ, Naumova AK, Morin D, et al. (2000) Report of 33 novel AVPR2 mutations and analysis of 117 families with X-linked nephrogenic diabetes insipidus. J Am Soc Nephrol 11: 1044-1054.
28. Seibold A, Brabet P, Rosenthal W, Birnbaumer M (1992) Structure and chromosomal localization of the human antidiuretic hormone receptor gene. Am J Hum Genet 51: 1078-1083.
29. Murasawa S, Matsubara H, Kijima K, Maruyama K, Mori Y, et al. (1995) Structure of the rat V1a vasopressin receptor gene and characterization of its promoter region and complete cDNA sequence of the 3′-end. J Biol Chem 270: 20042-20050.
30. Kubota Y, Kimura T, Hashimoto K, Tokugawa Y, Nobunaga K, et al. (1996) Structure and expression of the mouse oxytocin receptor gene. Mol Cell Endocrinol 124: 25-32.
31. Spanakis E, Milord E, Gragnoli C (2008) AVPR2 variants and mutations in nephrogenic diabetes insipidus: review and missense mutation significance. J Cell Physiol 217: 605-617.
32. Schulz A, Schoneberg T (2003) The structural evolution of a P2Y-like G-protein-coupled receptor. J Biol Chem 278: 35531-35541.
33. Staubert C, Tarnow P, Brumm H, Pitra C, Gudermann T, et al. (2007) Evolutionary aspects in evaluating mutations in the melanocortin 4 receptor. Endocrinology 148: 4642-4648.
34. Schoneberg T, Hermsdorf T, Engemaier E, Engel K, Liebscher I, et al. (2007) Structural and functional evolution of the P2Y(12)-like receptor group. Purinergic Signal 3: 255-268.
35. Schoneberg T, Yun J, Wenkert D, Wess J (1996) Functional rescue of mutant V2 vasopressin receptors causing nephrogenic diabetes insipidus by a co-expressed receptor polypeptide. Embo J 15: 1283-1291.
36. Pan Y, Wilson P, Gitschier J (1994) The effect of eight V2 vasopressin receptor mutations on stimulation of adenylyl cyclase and binding to vasopressin. J Biol Chem 269: 31933-31937.
37. Schulein R, Liebenhoff U, Muller H, Birnbaumer M, Rosenthal W (1996) Properties of the human arginine vasopressin V2 receptor after site-directed mutagenesis of its putative palmitoylation site. Biochem J 313(Pt 2): 611-616.
38. Schulein R, Hermosilla R, Oksche A, Dehe M, Wiesner B, et al. (1998) A dileucine sequence and an upstream glutamate residue in the intracellular carboxyl terminus of the vasopressin V2 receptor are essential for cell surface transport in COS.M6 cells. Mol Pharmacol 54: 525-535.
39. Krause G, Hermosilla R, Oksche A, Rutz C, Rosenthal W, et al. (2000) Molecular and conformational features of a transport-relevant domain in the C-terminal tail of the vasopressin V(2) receptor. Mol Pharmacol 57: 232-242.
40. Rovati GE, Capra V, Neubig RR (2007) The highly conserved DRY motif of class A G protein-coupled receptors: beyond the ground state. Mol Pharmacol 71: 959-964.
41. Wu S, Birnbaumer M, Guan Z (2008) Phosphorylation analysis of G protein-coupled receptor by mass spectrometry: identification of a phosphorylation site in V2 vasopressin receptor. Anal Chem 80: 6034-6037.
42. Innamorati G, Sadeghi H, Eberle AN, Birnbaumer M (1997) Phosphorylation of the V2 vasopressin receptor. J Biol Chem 272: 2486-2492.
43. Innamorati G, Sadeghi HM, Tran NT, Birnbaumer M (1998) A serine cluster prevents recycling of the V2 vasopressin receptor. Proc Natl Acad Sci U S A 95: 2222-2226.
44. Bichet DG (2008) Vasopressin receptor mutations in nephrogenic diabetes insipidus. Semin Nephrol 28: 245-251.
45. Ortiz RM (2001) Osmoregulation in marine mammals. J Exp Biol 204: 1831-1844.
46. King JM, Bradshaw SD (2008) Comparative water metabolism of Barrow Island macropodid marsupials: hormonal versus behavioural-dependent mechanisms of body water conservation. Gen Comp Endocrinol 155: 378-385.
47. Bradshaw SD, Morris KD, Bradshaw FJ (2001) Water and electrolyte homeostasis and kidney function of desert-dwelling marsupial wallabies in Western Australia. J Comp Physiol [B] 171: 22-32.
48. Dawson TJ, McTavish KJ, Munn AJ, Holloway J (2006) Water use and the thermoregulatory behaviour of kangaroos in arid regions: insights into the colonisation of arid rangelands in Australia by the Eastern Grey Kangaroo (Macropus giganteus). J Comp Physiol [B] 176: 45-53.
49. Brownfield MS, Wunder BA (1976) Relative medullary area: a new structural index for estimating urinary concentrating capacity of mammals. Comp Biochem Physiol A Comp Physiol 55: 69-75.
50. Schmidt-Nielsen B, O'Dell R (1961) Structure and concentrating mechanism in the mammalian kidney. Am J Physiol 200: 1119-1124.
51. Beuchat CA (1990) Body size, medullary thickness, and urine concentrating ability in mammals. Am J Physiol 258: R298-308.
52. Adan RA, Kas MJ (2003) Inverse agonism gains weight. Trends Pharmacol Sci 24: 315-321.
53. Kleinau G, Jaeschke H, Mueller S, Worth CL, Paschke R, et al. (2008) Molecular and structural effects of inverse agonistic mutations on signaling of the thyrotropin receptor-a basally active GPCR. Cell Mol Life Sci 65: 3664-3676.
54. Adan RA (2006) Constitutive receptor activity series: endogenous inverse agonists and constitutive receptor activity in the melanocortin system. Trends Pharmacol Sci 27: 183-186.
55. Ballesteros JA, Weinstein H (1995) Integrated methods for the construction of three-dimensional models and computational probing of structure-function relations in G protein-coupled receptors. Methods Neurosci 25: 366-428.
56. Sangkuhl K, Rompler H, Busch W, Karges B, Schoneberg T (2005) Nephrogenic diabetes insipidus caused by mutation of Tyr205: a key residue of V2 vasopressin receptor function. Hum Mutat 25: 505.
57. Schoneberg T, Schulz A, Biebermann H, Gruters A, Grimm T, et al. (1998) V2 vasopressin receptor dysfunction in nephrogenic diabetes insipidus caused by different molecular mechanisms. Hum Mutat 12: 196-205.