Quantitative expression profiling of G-protein-coupled receptors (GPCRs) in metastatic melanoma: The constitutively active orphan GPCR GPR18 as novel drug target

Pigment Cell and Melanoma Research

Volumn 24, Issue 1, 2011, Pages 207-218

  Qin, Y ^a   Verdegaal, E M E ^a   Siderius, M ^b   Bebelman, J P ^b   Smit, M J ^b   Leurs, R ^b   Willemze, R ^a   Tensen, C P ^a   Osanto, S ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Drug targeting; G protein coupled receptors; Gene expression; Melanoma; Metastases; Neoplasm; Orphan receptors

Indexed keywords

CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR6; G PROTEIN COUPLED RECEPTOR;

ADULT; AGED; APOPTOSIS; ARTICLE; BRAIN METASTASIS; CELL SURVIVAL; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG TARGETING; FEMALE; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; HUMAN; MALE; MELANOMA; MELANOMA CELL; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE; TUMOR CELL; YEAST;

ADULT; AGED; ANTINEOPLASTIC AGENTS; CLUSTER ANALYSIS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GENES, NEOPLASM; HUMANS; MALE; MELANOMA; MIDDLE AGED; NEOPLASM METASTASIS; NEVUS; RECEPTORS, G-PROTEIN-COUPLED; RNA, SMALL INTERFERING; SACCHAROMYCES CEREVISIAE; TRANSFECTION;

EID: 78651434044     PISSN: 17551471     EISSN: 1755148X     Source Type: Journal    
DOI: 10.1111/j.1755-148X.2010.00781.x     Document Type: Article

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