Molecular mechanism of action for reversible P2Y12 antagonists

Biophysical Chemistry

Volumn 155, Issue 2-3, 2011, Pages 74-81

  Liu, Haibo ^a   Ge, Hu ^b   Peng, Yong ^a   Xiao, Peigen ^a   Xu, Jun ^b  

^a INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

ADP; Antagonists; P2Y12 receptor; Platelets aggregation

Indexed keywords

ADENOSINE DIPHOSPHATE; CANGRELOR; CLOPIDOGREL; PRASUGREL; PURINERGIC P2Y12 RECEPTOR; PURINERGIC P2Y12 RECEPTOR ANTAGONIST; PURINERGIC RECEPTOR BLOCKING AGENT; PURINERGIC RECEPTOR STIMULATING AGENT; TICAGRELOR; TICLOPIDINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CHEMICAL INTERACTION; DRUG STRUCTURE; HYDROGEN BOND; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SIMULATION;

AMINO ACID SEQUENCE; ANIMALS; HUMANS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PURINERGIC P2Y RECEPTOR AGONISTS; PURINERGIC P2Y RECEPTOR ANTAGONISTS; RECEPTORS, PURINERGIC P2Y12; SEQUENCE ALIGNMENT;

EID: 79955478695     PISSN: 03014622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bpc.2011.03.001     Document Type: Article

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